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The map label for this gene is lytA [H]

Identifier: 187933828

GI number: 187933828

Start: 3413183

End: 3414967

Strand: Reverse

Name: lytA [H]

Synonym: CLL_A3257

Alternate gene names: 187933828

Gene position: 3414967-3413183 (Counterclockwise)

Preceding gene: 187932886

Following gene: 187934651

Centisome position: 89.86

GC content: 34.79

Gene sequence:

>1785_bases
ATGTTTAATAGAGCAAACAAAGCAACAGCTTTATTAGTAGCTGCGGCTGCTGTAATATCATTAGTTCCAGCTACTGGAGT
TAGTGCTGCTGATTATAAGAGAATAGAATCTAAAGATGGTACTGTATATAATGCGGTAGCTTACAAGAATGGATCTTTCG
TTATCGATGGTAATGTTAAAGATGAAGATACAGAAGCTGTATACTTCTTAAATGAAGGAAAATACTCTGAATTAGAAGAT
ATCGATACTGGAGCAGATTTCGATGGAACATACGGAGAAAAATATCTTTCTGTTGATGGTGGAGATTACTACGTTGATTT
AACAAACGGTAAAGTAACAGATAATGATGTAAAAGAAGATACAAGAGATGAAGTTGCTACAACTTTAAGAAAGAAAATCA
GAAACAATGCTGATGACAGATTTAAAGATCATGATTCATTAAAAGAGTCTTCATTAAAAGAAATGGCTGGAAACAAATTC
GGCGAAACTTGGTATGAAACTACTTATAAATCTGAAGAAGCTACAAATGGTGAAGCAGCTGAAACTGCATTAAATGTTTA
TACTGATGCAAAAGGTAACTACATAGATGCAGATTACAACTTAGGAAAAATCAAAGTAAAAGTTTCAAACGGAGAAACTA
CTAGCTCAGCTGTAACAGTTGACAATACTGATGATCAATTTGATGGATTAGCTAAAAATGATTTATCAGCTAATGTTTCA
AATGCAAAAGTAATAGGACAAGATTCTAACAACATATATAGAACAGCAACTATAACAGTTAATGCTGGAACTAACACTGT
TGTTGAAATCAATGGAAAAGAAGTAACTGTTGATGGAAAGACTTTCAAATCTGAAGACGGAAATAAAACAGTATCATTTG
AAGTTATTCAAAAGATATCTAAAGCTCAAGCTTCAGGAGATATCGATGGAGCTAAATATGCTAAAACTGTAACTAACTAC
GTTATAGCTGATGAAGATGCTAAAGCTGAAACTTTACTTGCTGATGCTGAATATAGCATAGTTGGTGGAAAAATTATAGC
TCATACATTTGCTTCAGAAAAAGTAAATGCTCAAACTATCGAATTCAAAACAAGCAGAGGATTCAATTACATTGATACTA
AAGAAGCTGATGAAGAAGAAGCTGTAGCTGTTGAAATTGATGCTGATGGAAACCTTTGGAGATTAGATTCAGGATTTGTT
TACAAATTCGATAACAAAGATGATTGGGATAAAGTTTACAAAGTAGACGGATCAATGGACAAAATGTCAGTTTACAACAA
AGACAACATGGTTGTTTGGAATGAAAGTGACGAAGTTTACTCAGTAATCGGAGCTAAAGATGAAGAAGAAAAGCCAGAAG
TAACAACTGGATGGGCTCAAGCTGAAGATGGAACTTGGAGTTACACTAAAGAAGATGGAACTAAAGCTACTGGATGGTTA
AACTTAAACGGTACTTGGTACTTCTTAGATGCAGCTGGAATCATGCAAACTGGTTGGATAAACGATAACGGAACTTGGTA
CTTAACTAATGGTTCAGGTGCTATGCAAACTGGATGGCAAAACGTTAATGGTACTTGGTACTTTATGCAAGGATCAGGAG
CAATGAAAACTGGTTGGATAAACGATAACGGAACTTGGTACTACACTAACGCTTCAGGTGCTATGCAAACTGGATGGTTA
AATGACAATGGTACTTGGTACTACTTAGATGGTTCAGGAAAAATGCTTTCAAACACAACTGTTAATGGTTATGTTTTAGG
AGCTAACGGAGCTTGGATCAGATAA

Upstream 100 bases:

>100_bases
ATTCCACAAAAACTCAAGAAAAGATTTTAAAATAACTCAAGAAGAAATTTTAAAATACTAAAGACAAAGAAATTTAAGTG
GAAAACTAGGAGGAAAAAAT

Downstream 100 bases:

>100_bases
TTTAAATTAAGCTTTTTATCATATTTAGATTATATATATTAGGTACTCCCCATATGGGAGTACCTTTTTTGTCCAAGCTG
GTGACTGTGACCAGCTTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: Cell wall hydrolase; Mucopeptide aminohydrolase; Murein hydrolase; N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MFNRANKATALLVAAAAVISLVPATGVSAADYKRIESKDGTVYNAVAYKNGSFVIDGNVKDEDTEAVYFLNEGKYSELED
IDTGADFDGTYGEKYLSVDGGDYYVDLTNGKVTDNDVKEDTRDEVATTLRKKIRNNADDRFKDHDSLKESSLKEMAGNKF
GETWYETTYKSEEATNGEAAETALNVYTDAKGNYIDADYNLGKIKVKVSNGETTSSAVTVDNTDDQFDGLAKNDLSANVS
NAKVIGQDSNNIYRTATITVNAGTNTVVEINGKEVTVDGKTFKSEDGNKTVSFEVIQKISKAQASGDIDGAKYAKTVTNY
VIADEDAKAETLLADAEYSIVGGKIIAHTFASEKVNAQTIEFKTSRGFNYIDTKEADEEEAVAVEIDADGNLWRLDSGFV
YKFDNKDDWDKVYKVDGSMDKMSVYNKDNMVVWNESDEVYSVIGAKDEEEKPEVTTGWAQAEDGTWSYTKEDGTKATGWL
NLNGTWYFLDAAGIMQTGWINDNGTWYLTNGSGAMQTGWQNVNGTWYFMQGSGAMKTGWINDNGTWYYTNASGAMQTGWL
NDNGTWYYLDGSGKMLSNTTVNGYVLGANGAWIR

Sequences:

>Translated_594_residues
MFNRANKATALLVAAAAVISLVPATGVSAADYKRIESKDGTVYNAVAYKNGSFVIDGNVKDEDTEAVYFLNEGKYSELED
IDTGADFDGTYGEKYLSVDGGDYYVDLTNGKVTDNDVKEDTRDEVATTLRKKIRNNADDRFKDHDSLKESSLKEMAGNKF
GETWYETTYKSEEATNGEAAETALNVYTDAKGNYIDADYNLGKIKVKVSNGETTSSAVTVDNTDDQFDGLAKNDLSANVS
NAKVIGQDSNNIYRTATITVNAGTNTVVEINGKEVTVDGKTFKSEDGNKTVSFEVIQKISKAQASGDIDGAKYAKTVTNY
VIADEDAKAETLLADAEYSIVGGKIIAHTFASEKVNAQTIEFKTSRGFNYIDTKEADEEEAVAVEIDADGNLWRLDSGFV
YKFDNKDDWDKVYKVDGSMDKMSVYNKDNMVVWNESDEVYSVIGAKDEEEKPEVTTGWAQAEDGTWSYTKEDGTKATGWL
NLNGTWYFLDAAGIMQTGWINDNGTWYLTNGSGAMQTGWQNVNGTWYFMQGSGAMKTGWINDNGTWYYTNASGAMQTGWL
NDNGTWYYLDGSGKMLSNTTVNGYVLGANGAWIR
>Mature_594_residues
MFNRANKATALLVAAAAVISLVPATGVSAADYKRIESKDGTVYNAVAYKNGSFVIDGNVKDEDTEAVYFLNEGKYSELED
IDTGADFDGTYGEKYLSVDGGDYYVDLTNGKVTDNDVKEDTRDEVATTLRKKIRNNADDRFKDHDSLKESSLKEMAGNKF
GETWYETTYKSEEATNGEAAETALNVYTDAKGNYIDADYNLGKIKVKVSNGETTSSAVTVDNTDDQFDGLAKNDLSANVS
NAKVIGQDSNNIYRTATITVNAGTNTVVEINGKEVTVDGKTFKSEDGNKTVSFEVIQKISKAQASGDIDGAKYAKTVTNY
VIADEDAKAETLLADAEYSIVGGKIIAHTFASEKVNAQTIEFKTSRGFNYIDTKEADEEEAVAVEIDADGNLWRLDSGFV
YKFDNKDDWDKVYKVDGSMDKMSVYNKDNMVVWNESDEVYSVIGAKDEEEKPEVTTGWAQAEDGTWSYTKEDGTKATGWL
NLNGTWYFLDAAGIMQTGWINDNGTWYLTNGSGAMQTGWQNVNGTWYFMQGSGAMKTGWINDNGTWYYTNASGAMQTGWL
NDNGTWYYLDGSGKMLSNTTVNGYVLGANGAWIR

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR018337 [H]

Pfam domain/function: PF01510 Amidase_2; PF01473 CW_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 65195; Mature: 65195

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNRANKATALLVAAAAVISLVPATGVSAADYKRIESKDGTVYNAVAYKNGSFVIDGNVK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEEECCCEEEECCCC
DEDTEAVYFLNEGKYSELEDIDTGADFDGTYGEKYLSVDGGDYYVDLTNGKVTDNDVKED
CCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCEEEEEECCCEECCCCCCHH
TRDEVATTLRKKIRNNADDRFKDHDSLKESSLKEMAGNKFGETWYETTYKSEEATNGEAA
HHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCHH
ETALNVYTDAKGNYIDADYNLGKIKVKVSNGETTSSAVTVDNTDDQFDGLAKNDLSANVS
HEEEEEEECCCCCEEECCCCCEEEEEEECCCCCCCCEEEECCCCCHHCCCCCCCCCCCCC
NAKVIGQDSNNIYRTATITVNAGTNTVVEINGKEVTVDGKTFKSEDGNKTVSFEVIQKIS
CEEEEECCCCCEEEEEEEEEECCCCEEEEECCCEEEECCCEEECCCCCEEEEHHHHHHHH
KAQASGDIDGAKYAKTVTNYVIADEDAKAETLLADAEYSIVGGKIIAHTFASEKVNAQTI
HHHCCCCCCHHHHHHHHHEEEEECCCCCCEEEEECCCEEEECCEEEEEECCCCCCCCEEE
EFKTSRGFNYIDTKEADEEEAVAVEIDADGNLWRLDSGFVYKFDNKDDWDKVYKVDGSMD
EEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCEEEEECCCCCCCCEEEECCCCC
KMSVYNKDNMVVWNESDEVYSVIGAKDEEEKPEVTTGWAQAEDGTWSYTKEDGTKATGWL
EEEEECCCCEEEECCCCCEEEEECCCCCCCCCCEEECEEECCCCCEEEECCCCCEEEEEE
NLNGTWYFLDAAGIMQTGWINDNGTWYLTNGSGAMQTGWQNVNGTWYFMQGSGAMKTGWI
EECCEEEEEECCCEEEECEECCCCEEEEECCCCCEECCCCCCCEEEEEEECCCCEEEEEE
NDNGTWYYTNASGAMQTGWLNDNGTWYYLDGSGKMLSNTTVNGYVLGANGAWIR
CCCCCEEEECCCCCEEECEECCCCEEEEECCCCCEEECCEEEEEEECCCCCCCC
>Mature Secondary Structure
MFNRANKATALLVAAAAVISLVPATGVSAADYKRIESKDGTVYNAVAYKNGSFVIDGNVK
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEEECCCEEEECCCC
DEDTEAVYFLNEGKYSELEDIDTGADFDGTYGEKYLSVDGGDYYVDLTNGKVTDNDVKED
CCCCCEEEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCEEEEEECCCEECCCCCCHH
TRDEVATTLRKKIRNNADDRFKDHDSLKESSLKEMAGNKFGETWYETTYKSEEATNGEAA
HHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCHH
ETALNVYTDAKGNYIDADYNLGKIKVKVSNGETTSSAVTVDNTDDQFDGLAKNDLSANVS
HEEEEEEECCCCCEEECCCCCEEEEEEECCCCCCCCEEEECCCCCHHCCCCCCCCCCCCC
NAKVIGQDSNNIYRTATITVNAGTNTVVEINGKEVTVDGKTFKSEDGNKTVSFEVIQKIS
CEEEEECCCCCEEEEEEEEEECCCCEEEEECCCEEEECCCEEECCCCCEEEEHHHHHHHH
KAQASGDIDGAKYAKTVTNYVIADEDAKAETLLADAEYSIVGGKIIAHTFASEKVNAQTI
HHHCCCCCCHHHHHHHHHEEEEECCCCCCEEEEECCCEEEECCEEEEEECCCCCCCCEEE
EFKTSRGFNYIDTKEADEEEAVAVEIDADGNLWRLDSGFVYKFDNKDDWDKVYKVDGSMD
EEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCEEEEECCCCCCCCEEEECCCCC
KMSVYNKDNMVVWNESDEVYSVIGAKDEEEKPEVTTGWAQAEDGTWSYTKEDGTKATGWL
EEEEECCCCEEEECCCCCEEEEECCCCCCCCCCEEECEEECCCCCEEEECCCCCEEEEEE
NLNGTWYFLDAAGIMQTGWINDNGTWYLTNGSGAMQTGWQNVNGTWYFMQGSGAMKTGWI
EECCEEEEEECCCEEEECEECCCCEEEEECCCCCEECCCCCCCEEEEEEECCCCEEEEEE
NDNGTWYYTNASGAMQTGWLNDNGTWYYLDGSGKMLSNTTVNGYVLGANGAWIR
CCCCCEEEECCCCCEEECEECCCCEEEEECCCCCEEECCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2875013; 11463916 [H]