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The map label for this gene is dacC [H]

Identifier: 187918466

GI number: 187918466

Start: 639525

End: 640475

Strand: Direct

Name: dacC [H]

Synonym: BH0605

Alternate gene names: 187918466

Gene position: 639525-640475 (Clockwise)

Preceding gene: 187918463

Following gene: 187918467

Centisome position: 69.34

GC content: 29.34

Gene sequence:

>951_bases
ATGAAAATTGTCTTTACTATTCTAAGCTTTTTAATTTTATTTAGTATATTTGGTAAGCTTTTCTCAATTGATTTATTTGA
TATTGAGAGAGTAACTGAAGATGCTAAATCAGTTGTTTTGATTGATTATGATACTAAACGTATTTTTTATGCCAAAAATC
CAAATTTAGTTTTTCCACCAGCATCGCTTACTAAGCTTGTTACTATTTATACTGCTTTAGTTGAGGCAAGAAAAAAAAAT
ATAGATTTAAAGACTATTGTTCCTATTAGCAGTGCCGCATCGTATTATAATCTGCCTTTAGGTTCTTCATTAATGTTTTT
AGAAGAGGGTCATAAGGTGAATTTTGAGGAGTTGCTTAAAGGTCTTGTGATTTCTTCAGGTAATGATGCTGCTATTGCAA
TTGCTGAATTTATAGTTGGGAAGAATTTAAGCAATTTTGTTAATTTAATGAATATTAATGTTTTAAACTTGGGACTTGTA
AATATGAATTTTGTTGATACATCGGGTTATTGCAATGGTAATCAGATCACAGCATTAGAAATGGCATTGTTTGCAAGAAC
TTACATAGAGGAATTTGAATTTATGCTTGCTATACATTCTCTTAAAGATTTTATTTATCCAAGGTCTGAAAATTTAGGCA
ATACTTCTTCTTCAAAGATGTTAAATTTAAAACAAGAGAATAGAAATGTTTTGATATTTAATTATCCTTATGCTGATGGA
TTAAAAACCGGTTATATTAAGACATCTGGTTTAAATTTAGTCGCTACAGCCAAAAAAGATGATATAAGATTAATAGCGGT
TGTCTTGGGGGTTAATAAGGGAATTAATAGCGTTGGAGAGAAAAAGCGTGCCTTAATTGCACAGAAATTATTTGAATATG
GCTTTAGTAATTATTCTCGATTTCCTTTCATTGGTAAAATTAGAAAAAAGATCTATAATGGGACATGGTAA

Upstream 100 bases:

>100_bases
AATGAAATCATAAAAATTCATAATAAGATATGCGCTCCTTTTTAGATTTACCATTTAATTTTATAACAAATTTTTATACA
ATAACACATAATATTGCTTT

Downstream 100 bases:

>100_bases
ATATTTCTTTTAAAAAGCTTTTTAATCTTTTTTTTGAAGAGATACAGTTTAAGGCAGTAGAGTCTAGTATAAAAGCATTA
ATTGCTCCACTTGAAAATAA

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKIVFTILSFLILFSIFGKLFSIDLFDIERVTEDAKSVVLIDYDTKRIFYAKNPNLVFPPASLTKLVTIYTALVEARKKN
IDLKTIVPISSAASYYNLPLGSSLMFLEEGHKVNFEELLKGLVISSGNDAAIAIAEFIVGKNLSNFVNLMNINVLNLGLV
NMNFVDTSGYCNGNQITALEMALFARTYIEEFEFMLAIHSLKDFIYPRSENLGNTSSSKMLNLKQENRNVLIFNYPYADG
LKTGYIKTSGLNLVATAKKDDIRLIAVVLGVNKGINSVGEKKRALIAQKLFEYGFSNYSRFPFIGKIRKKIYNGTW

Sequences:

>Translated_316_residues
MKIVFTILSFLILFSIFGKLFSIDLFDIERVTEDAKSVVLIDYDTKRIFYAKNPNLVFPPASLTKLVTIYTALVEARKKN
IDLKTIVPISSAASYYNLPLGSSLMFLEEGHKVNFEELLKGLVISSGNDAAIAIAEFIVGKNLSNFVNLMNINVLNLGLV
NMNFVDTSGYCNGNQITALEMALFARTYIEEFEFMLAIHSLKDFIYPRSENLGNTSSSKMLNLKQENRNVLIFNYPYADG
LKTGYIKTSGLNLVATAKKDDIRLIAVVLGVNKGINSVGEKKRALIAQKLFEYGFSNYSRFPFIGKIRKKIYNGTW
>Mature_316_residues
MKIVFTILSFLILFSIFGKLFSIDLFDIERVTEDAKSVVLIDYDTKRIFYAKNPNLVFPPASLTKLVTIYTALVEARKKN
IDLKTIVPISSAASYYNLPLGSSLMFLEEGHKVNFEELLKGLVISSGNDAAIAIAEFIVGKNLSNFVNLMNINVLNLGLV
NMNFVDTSGYCNGNQITALEMALFARTYIEEFEFMLAIHSLKDFIYPRSENLGNTSSSKMLNLKQENRNVLIFNYPYADG
LKTGYIKTSGLNLVATAKKDDIRLIAVVLGVNKGINSVGEKKRALIAQKLFEYGFSNYSRFPFIGKIRKKIYNGTW

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=298, Percent_Identity=33.8926174496644, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082022, Length=279, Percent_Identity=34.0501792114695, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786851, Length=269, Percent_Identity=34.5724907063197, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 35479; Mature: 35479

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVFTILSFLILFSIFGKLFSIDLFDIERVTEDAKSVVLIDYDTKRIFYAKNPNLVFPP
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECCCEEEEECCCCEEECC
ASLTKLVTIYTALVEARKKNIDLKTIVPISSAASYYNLPLGSSLMFLEEGHKVNFEELLK
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCCCCEEEEEECCCCCCHHHHHH
GLVISSGNDAAIAIAEFIVGKNLSNFVNLMNINVLNLGLVNMNFVDTSGYCNGNQITALE
HHEECCCCCHHHHHHHHHHCCCHHHHHHHHEEEEEEEEEEEEEEEECCCCCCCCEEHHHH
MALFARTYIEEFEFMLAIHSLKDFIYPRSENLGNTSSSKMLNLKQENRNVLIFNYPYADG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCEEEEECCCCCC
LKTGYIKTSGLNLVATAKKDDIRLIAVVLGVNKGINSVGEKKRALIAQKLFEYGFSNYSR
CCCCEEEECCCEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
FPFIGKIRKKIYNGTW
CCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIVFTILSFLILFSIFGKLFSIDLFDIERVTEDAKSVVLIDYDTKRIFYAKNPNLVFPP
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECCCEEEEECCCCEEECC
ASLTKLVTIYTALVEARKKNIDLKTIVPISSAASYYNLPLGSSLMFLEEGHKVNFEELLK
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCCCCEEEEEECCCCCCHHHHHH
GLVISSGNDAAIAIAEFIVGKNLSNFVNLMNINVLNLGLVNMNFVDTSGYCNGNQITALE
HHEECCCCCHHHHHHHHHHCCCHHHHHHHHEEEEEEEEEEEEEEEECCCCCCCCEEHHHH
MALFARTYIEEFEFMLAIHSLKDFIYPRSENLGNTSSSKMLNLKQENRNVLIFNYPYADG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCEEEEECCCCCC
LKTGYIKTSGLNLVATAKKDDIRLIAVVLGVNKGINSVGEKKRALIAQKLFEYGFSNYSR
CCCCEEEECCCEEEEECCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
FPFIGKIRKKIYNGTW
CCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]