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The map label for this gene is yggB [C]

Identifier: 187918319

GI number: 187918319

Start: 477478

End: 478344

Strand: Direct

Name: yggB [C]

Synonym: BH0453

Alternate gene names: 187918319

Gene position: 477478-478344 (Clockwise)

Preceding gene: 187918312

Following gene: 187918321

Centisome position: 51.77

GC content: 30.22

Gene sequence:

>867_bases
ATGAATGAACAGTTAGGAACATTGAATTTATTTAAAGAAATATCTATTTTTCAGGATTATATTAATACAATTTTTGAAAC
GGTACTAGGTTATGGATTAAAAGTTTTAGTAGCACTATTAGTGTGGTACATTTTAAGGTTTGTTATTAAGAGGATGGGTA
AGTTTTTTTTTAAGGCTTTTGAAAAATCTAAGTTGGAGACGAAGCTAGATTCTACTGTTCTTAATTTTTTTAAGTCATTT
TTTGCAGTGATGACAGATATGGTGTTAATTCTGGTGATTTTGCCTTATCTTGGTGTTCCTACGACTTCTGTTTTTGCTAT
ATTTGGATCTCTAGGTCTTGCAGTTGGTCTTGCTGCTCAAGGAATTTTATCTAACTTTGTTAGTGGATTTATTGTTCTAA
ATTCCAATTTTTTTAAAATCGGCGATCACATTAGCTGTGATGATGTTGAGGGTGAGGTAAATGATATTCAGATATTTTTT
ACTACACTTAAGACTGTAGATGGTAAGATTATTAAGATTCCAAATAGTAAGTTTACAAGTACATCAGTTACTAATTTTTC
TGCAAATCCTAAAAGGAGGATTGCATTCAGTTTTCAAGTGCCTTATGATACAGATATTGATGTTCTTAAAAGCAAGATAG
AAAATTTGGCATTCTCAGTTAATAGGGAACAATATGGTGTTAAGGATCCCAGTGTTATTGTAAAGGAATATACGCCTTAT
TACGTAGTCATGCAAGTTAGATGTTTTGTAAAGACTGAGTTTTTTTGGGATTTTCAATATTTCATAGCAGAAAATATTAA
AGGTATTTTAAGTGATATGGGAATAAAATTTCCCATTCATATTGTGGATTTTAGCAAATTGCATTAA

Upstream 100 bases:

>100_bases
TGTGATAGGTGCTTTTGTATATTAATTTTTTGTTTTGGAGCTGAGTATTTTAAGATTGTATTTTCCTATTATTTTTTTAT
ACTATTAACCATGGTAGCTT

Downstream 100 bases:

>100_bases
TATCTTGAGTTGTTAATGATTTCGGAATAATACTGTTCAATTTTTTCTATAAAGAGTGAGCTTGAAAACATCATAGACGT
TTCTTCTGTGGTTCTTTTTA

Product: mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNEQLGTLNLFKEISIFQDYINTIFETVLGYGLKVLVALLVWYILRFVIKRMGKFFFKAFEKSKLETKLDSTVLNFFKSF
FAVMTDMVLILVILPYLGVPTTSVFAIFGSLGLAVGLAAQGILSNFVSGFIVLNSNFFKIGDHISCDDVEGEVNDIQIFF
TTLKTVDGKIIKIPNSKFTSTSVTNFSANPKRRIAFSFQVPYDTDIDVLKSKIENLAFSVNREQYGVKDPSVIVKEYTPY
YVVMQVRCFVKTEFFWDFQYFIAENIKGILSDMGIKFPIHIVDFSKLH

Sequences:

>Translated_288_residues
MNEQLGTLNLFKEISIFQDYINTIFETVLGYGLKVLVALLVWYILRFVIKRMGKFFFKAFEKSKLETKLDSTVLNFFKSF
FAVMTDMVLILVILPYLGVPTTSVFAIFGSLGLAVGLAAQGILSNFVSGFIVLNSNFFKIGDHISCDDVEGEVNDIQIFF
TTLKTVDGKIIKIPNSKFTSTSVTNFSANPKRRIAFSFQVPYDTDIDVLKSKIENLAFSVNREQYGVKDPSVIVKEYTPY
YVVMQVRCFVKTEFFWDFQYFIAENIKGILSDMGIKFPIHIVDFSKLH
>Mature_288_residues
MNEQLGTLNLFKEISIFQDYINTIFETVLGYGLKVLVALLVWYILRFVIKRMGKFFFKAFEKSKLETKLDSTVLNFFKSF
FAVMTDMVLILVILPYLGVPTTSVFAIFGSLGLAVGLAAQGILSNFVSGFIVLNSNFFKIGDHISCDDVEGEVNDIQIFF
TTLKTVDGKIIKIPNSKFTSTSVTNFSANPKRRIAFSFQVPYDTDIDVLKSKIENLAFSVNREQYGVKDPSVIVKEYTPY
YVVMQVRCFVKTEFFWDFQYFIAENIKGILSDMGIKFPIHIVDFSKLH

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=253, Percent_Identity=33.201581027668, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787591, Length=146, Percent_Identity=32.8767123287671, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786670, Length=177, Percent_Identity=23.728813559322, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014
- InterPro:   IPR008910 [H]

Pfam domain/function: PF00924 MS_channel; PF05552 TM_helix [H]

EC number: NA

Molecular weight: Translated: 32838; Mature: 32838

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQLGTLNLFKEISIFQDYINTIFETVLGYGLKVLVALLVWYILRFVIKRMGKFFFKAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKSKLETKLDSTVLNFFKSFFAVMTDMVLILVILPYLGVPTTSVFAIFGSLGLAVGLAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GILSNFVSGFIVLNSNFFKIGDHISCDDVEGEVNDIQIFFTTLKTVDGKIIKIPNSKFTS
HHHHHHHHEEEEECCCEEECCCCCCCCCCCCCCCHHEEHEEEHHHCCCEEEECCCCCCCC
TSVTNFSANPKRRIAFSFQVPYDTDIDVLKSKIENLAFSVNREQYGVKDPSVIVKEYTPY
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCHHCCCCCCCHHHCCCCCE
YVVMQVRCFVKTEFFWDFQYFIAENIKGILSDMGIKFPIHIVDFSKLH
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MNEQLGTLNLFKEISIFQDYINTIFETVLGYGLKVLVALLVWYILRFVIKRMGKFFFKAF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKSKLETKLDSTVLNFFKSFFAVMTDMVLILVILPYLGVPTTSVFAIFGSLGLAVGLAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GILSNFVSGFIVLNSNFFKIGDHISCDDVEGEVNDIQIFFTTLKTVDGKIIKIPNSKFTS
HHHHHHHHEEEEECCCEEECCCCCCCCCCCCCCCHHEEHEEEHHHCCCEEEECCCCCCCC
TSVTNFSANPKRRIAFSFQVPYDTDIDVLKSKIENLAFSVNREQYGVKDPSVIVKEYTPY
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEECCCHHCCCCCCCHHHCCCCCE
YVVMQVRCFVKTEFFWDFQYFIAENIKGILSDMGIKFPIHIVDFSKLH
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]