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The map label for this gene is gatR

Identifier: 187732335

GI number: 187732335

Start: 1039880

End: 1040653

Strand: Direct

Name: gatR

Synonym: SbBS512_E1148

Alternate gene names: 187732335

Gene position: 1039880-1040653 (Clockwise)

Preceding gene: 187733813

Following gene: 187730403

Centisome position: 22.53

GC content: 46.51

Gene sequence:

>774_bases
ATGAATTCATTCGAGCGAAGGAATAAGATCATCCAATTAGTGAATGAACAGGGAACCGTGCTTGTTCAGGATCTGGCGGG
AGTATTTGCTGCCTCGGAAGCGACAATCCGTGCCGATTTGCGCTTTCTCGAACAAAAAGGCGTGGTTACGCGCTTTCATG
GCGGTGCGGCGAAAATAATGTCCGGTAATAGTGAAACCGAGACCCAGGAAGTCGGGTTTAAAGAGCGATTTCAGCTCGCC
AGCGCGCCAAAAAACAGAATAGCGCAGGCGGCAGTCAAAATGATCCATGAAGGGATGACCGTTATTCTCGACAGCGGAAG
TACCACAATGCTTATCGCCGAAGGATTAATGACCGCTAAAAATATCACGGTGATTACCAACAGTCTCCCGGCAGCGTTTG
CCCTTTCCGAAAATAAAGACATTACTCTGGTCGTCTGTGGTGGCACGGTCCGCCATAAAACGCGCTCGATGCATGGTTCC
ATTGCCGAGCGTTCATTGCAGGATATTAATGCCGATTTAATGTTTGTCGGTGCTGATGGTATTGATGCGGTTAATGGTAT
TACGACCTTTAATGAAGGTTATTCGATTAGCGGTGCGATGGTCACCGCCGCTAATAAAGTGATTGCCGTTCTCGATTCAT
CGAAATTTAACCGTCGCGGTTTTAATCAGGTACTGCCAATCGAAAAAATTGACATTATTATTACCGATGATGCTGTATCA
GAGGTGGATAAACTGGCATTGCAGAAGACACGGGTAAAATTAATTACGGTGTAG

Upstream 100 bases:

>100_bases
CGGGCCAGCGTGATGCTGGCCCGGTATTGTGCAAAACAGATCATTCACCAATGGTCCCCCTTCGTTTACACTAGCCACAA
TTGAATATGGGTAAATGACG

Downstream 100 bases:

>100_bases
TATTGTTCTGTATGCCGGATAAGGTATTTACACCTCATCCGGCATTACGGATTCTCCCTGGTTCAAGAGAGAATAGTTTG
ATTAACGCAATAATGGACAA

Product: galactitol utilization operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLA
SAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAVS
EVDKLALQKTRVKLITV

Sequences:

>Translated_257_residues
MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLA
SAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAVS
EVDKLALQKTRVKLITV
>Mature_257_residues
MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLA
SAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAVS
EVDKLALQKTRVKLITV

Specific function: Repressor of the gat operon for galacticol transport and metabolism

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=37.7952755905512, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=39.0625, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=31.25, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=32.4894514767932, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787540, Length=259, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=29.1139240506329, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=24.901185770751, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790753, Length=255, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790635, Length=242, Percent_Identity=26.8595041322314, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GATR_ECOLI (P36930)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X79837
- EMBL:   D12598
- EMBL:   X64217
- EMBL:   X64218
- ProteinModelPortal:   P36930
- EchoBASE:   EB2081
- EcoGene:   EG12162
- BioCyc:   EcoCyc:PD00338
- BioCyc:   EcoCyc:PD02366
- Genevestigator:   P36930
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 27727; Mature: 27727

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIM
CCCHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEEEE
SGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAK
CCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHCCC
NITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGADG
CEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAVS
CCHHCCEEECCCCCEECCEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECHHHH
EVDKLALQKTRVKLITV
HHHHHHHHHHEEEEEEC
>Mature Secondary Structure
MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIM
CCCHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEEEE
SGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAK
CCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHCCC
NITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGADG
CEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
IDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAVS
CCHHCCEEECCCCCEECCEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECHHHH
EVDKLALQKTRVKLITV
HHHHHHHHHHEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252