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The map label for this gene is bepF [H]

Identifier: 187736508

GI number: 187736508

Start: 2462442

End: 2463578

Strand: Direct

Name: bepF [H]

Synonym: Amuc_2029

Alternate gene names: 187736508

Gene position: 2462442-2463578 (Clockwise)

Preceding gene: 187736507

Following gene: 187736509

Centisome position: 92.43

GC content: 55.94

Gene sequence:

>1137_bases
ATGAAAAAACACACGCATCATCGGAAGGCGCCCCTCCGCCTGCTGGCCGGTTCCGGCCTGCTTTTTTCCCTGTTTGTTCC
GGGTTATTCCCAAGGAACGCCGGGAGGGGCTGCAGCCAAACCCAGTACCGTACTCGTCCAGAAAGCCGCCGCTATTGACA
GCGCGGTGAACAAGAAGTACATCGGCCAGGTGGAAGCCATTGACCGGGTGACTGTGCAGCCCCGCGTCTCCGGCAACATC
GTAGCCACCCGTTTCCGGGAAGGAAAGGTCGTGAAGAAGGGGGATCTCCTGTTCGAAATTGAGGATACGCGCTACAGGGC
GGCTGTGGAGGAAGCGGTAGCCAAAAAGGCCCAGCTTGAAGCCAAACTGCTTTACGCAAAAAATAGTTTTGAACGCTATA
ACAGGTTGCTGGCCTCCAAATCCGTCTCCATGGACACGGTGGAAAACGCCAAGAGCACCATGCATGCCCTGGAAGCGGAA
ATCCAGTCCGCAAACGCCGCCATTACGGTAGCGAAGGACGATCTTAACTATACCAGGCTCACGGCTCCCATCACGGGCCG
CACAGGCCGCGTCACCTTTTCCACGGGCAATTACATCACCCCCACCTCCGGTTCCCTGGTGACCATTACAGGCATCGATG
AAGTGTACGTGAAGTTCCCTATCAGCGAACGCGATTTCCTTTCCCTGTTCGGTACCCAGGAAAATATGAAGAAAGACGCC
CTTGTGTCCGTCAACCTCGCCAACGGCAAGGCATACGACCAGCCGGGCAGGATTTTCATGACGGACAATACCGTCCAGAC
GACCACGGACACCCTGAATGTCTGGGCAAAATTCCCCAATCCGGAAGACGTGCTGACGCCCGGCGGCGTAGTCACGGTTA
ATCTTTCCAAGAAAAACGTGGACCGCTTCCCGGCTGCCAACATTTCCTCCGTGATGCACGATGCCTACAAGAGCTACGTT
TACATCGTCAACGACCAGGGCGTCGTGGAACGCCGGGACGTTACGCTGGGCAACACGGTCAATAATGAACAGTGTTTCAG
TTCCGGCGTTAAGGAAGGGGAAGTCGTCATCATCGACGGCATGCACAAGGTGCGTCCCGGCGCCAAGGTGAATCCGGTAT
ATTCCGTTCAAAACTGA

Upstream 100 bases:

>100_bases
ACTGGATACCCTGTTCAGCACTCTGTCGCAAGAGGACAAGGAGAATTTCTGCCGTATTGTGGATACCCTTTACAACCACG
TTTACAGTAAATAATACCAT

Downstream 100 bases:

>100_bases
GCTACCCATGATTGCGGACCTGTTTATCAAACGCCCCAAATTCGCCATCGTCATCGCCATCCTGATGATGCTGGCTGGCG
GCATCTGCCTGAACCAGCTC

Product: efflux transporter, RND family, MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKKHTHHRKAPLRLLAGSGLLFSLFVPGYSQGTPGGAAAKPSTVLVQKAAAIDSAVNKKYIGQVEAIDRVTVQPRVSGNI
VATRFREGKVVKKGDLLFEIEDTRYRAAVEEAVAKKAQLEAKLLYAKNSFERYNRLLASKSVSMDTVENAKSTMHALEAE
IQSANAAITVAKDDLNYTRLTAPITGRTGRVTFSTGNYITPTSGSLVTITGIDEVYVKFPISERDFLSLFGTQENMKKDA
LVSVNLANGKAYDQPGRIFMTDNTVQTTTDTLNVWAKFPNPEDVLTPGGVVTVNLSKKNVDRFPAANISSVMHDAYKSYV
YIVNDQGVVERRDVTLGNTVNNEQCFSSGVKEGEVVIIDGMHKVRPGAKVNPVYSVQN

Sequences:

>Translated_378_residues
MKKHTHHRKAPLRLLAGSGLLFSLFVPGYSQGTPGGAAAKPSTVLVQKAAAIDSAVNKKYIGQVEAIDRVTVQPRVSGNI
VATRFREGKVVKKGDLLFEIEDTRYRAAVEEAVAKKAQLEAKLLYAKNSFERYNRLLASKSVSMDTVENAKSTMHALEAE
IQSANAAITVAKDDLNYTRLTAPITGRTGRVTFSTGNYITPTSGSLVTITGIDEVYVKFPISERDFLSLFGTQENMKKDA
LVSVNLANGKAYDQPGRIFMTDNTVQTTTDTLNVWAKFPNPEDVLTPGGVVTVNLSKKNVDRFPAANISSVMHDAYKSYV
YIVNDQGVVERRDVTLGNTVNNEQCFSSGVKEGEVVIIDGMHKVRPGAKVNPVYSVQN
>Mature_378_residues
MKKHTHHRKAPLRLLAGSGLLFSLFVPGYSQGTPGGAAAKPSTVLVQKAAAIDSAVNKKYIGQVEAIDRVTVQPRVSGNI
VATRFREGKVVKKGDLLFEIEDTRYRAAVEEAVAKKAQLEAKLLYAKNSFERYNRLLASKSVSMDTVENAKSTMHALEAE
IQSANAAITVAKDDLNYTRLTAPITGRTGRVTFSTGNYITPTSGSLVTITGIDEVYVKFPISERDFLSLFGTQENMKKDA
LVSVNLANGKAYDQPGRIFMTDNTVQTTTDTLNVWAKFPNPEDVLTPGGVVTVNLSKKNVDRFPAANISSVMHDAYKSYV
YIVNDQGVVERRDVTLGNTVNNEQCFSSGVKEGEVVIIDGMHKVRPGAKVNPVYSVQN

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=316, Percent_Identity=31.3291139240506, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082036, Length=335, Percent_Identity=28.955223880597, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789665, Length=388, Percent_Identity=28.8659793814433, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786668, Length=320, Percent_Identity=30.3125, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081796, Length=328, Percent_Identity=25.609756097561, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081951, Length=137, Percent_Identity=29.9270072992701, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789637, Length=142, Percent_Identity=30.2816901408451, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41208; Mature: 41208

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKHTHHRKAPLRLLAGSGLLFSLFVPGYSQGTPGGAAAKPSTVLVQKAAAIDSAVNKKY
CCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHH
IGQVEAIDRVTVQPRVSGNIVATRFREGKVVKKGDLLFEIEDTRYRAAVEEAVAKKAQLE
CCCCHHCEEEEECCCCCCCEEEEEECCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHH
AKLLYAKNSFERYNRLLASKSVSMDTVENAKSTMHALEAEIQSANAAITVAKDDLNYTRL
EEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEE
TAPITGRTGRVTFSTGNYITPTSGSLVTITGIDEVYVKFPISERDFLSLFGTQENMKKDA
EEEECCCCCEEEECCCCEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHCCHHCCCCCE
LVSVNLANGKAYDQPGRIFMTDNTVQTTTDTLNVWAKFPNPEDVLTPGGVVTVNLSKKNV
EEEEEECCCCCCCCCCEEEEECCCEEEECCEEEEEEECCCCCCCCCCCCEEEEEECCCCC
DRFPAANISSVMHDAYKSYVYIVNDQGVVERRDVTLGNTVNNEQCFSSGVKEGEVVIIDG
CCCCCCHHHHHHHHHHHCEEEEECCCCCEEECCEEECCCCCCHHHHHCCCCCCCEEEEEC
MHKVRPGAKVNPVYSVQN
CHHCCCCCCCCCEEECCC
>Mature Secondary Structure
MKKHTHHRKAPLRLLAGSGLLFSLFVPGYSQGTPGGAAAKPSTVLVQKAAAIDSAVNKKY
CCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHH
IGQVEAIDRVTVQPRVSGNIVATRFREGKVVKKGDLLFEIEDTRYRAAVEEAVAKKAQLE
CCCCHHCEEEEECCCCCCCEEEEEECCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHH
AKLLYAKNSFERYNRLLASKSVSMDTVENAKSTMHALEAEIQSANAAITVAKDDLNYTRL
EEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEE
TAPITGRTGRVTFSTGNYITPTSGSLVTITGIDEVYVKFPISERDFLSLFGTQENMKKDA
EEEECCCCCEEEECCCCEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHCCHHCCCCCE
LVSVNLANGKAYDQPGRIFMTDNTVQTTTDTLNVWAKFPNPEDVLTPGGVVTVNLSKKNV
EEEEEECCCCCCCCCCEEEEECCCEEEECCEEEEEEECCCCCCCCCCCCEEEEEECCCCC
DRFPAANISSVMHDAYKSYVYIVNDQGVVERRDVTLGNTVNNEQCFSSGVKEGEVVIIDG
CCCCCCHHHHHHHHHHHCEEEEECCCCCEEECCEEECCCCCCHHHHHCCCCCCCEEEEEC
MHKVRPGAKVNPVYSVQN
CHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]