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The map label for this gene is hprK [H]

Identifier: 187736245

GI number: 187736245

Start: 2140726

End: 2141688

Strand: Reverse

Name: hprK [H]

Synonym: Amuc_1758

Alternate gene names: 187736245

Gene position: 2141688-2140726 (Counterclockwise)

Preceding gene: 187736249

Following gene: 187736244

Centisome position: 80.39

GC content: 59.71

Gene sequence:

>963_bases
ATGTTCAGCAAATCCAAAGTGAAGAAAGTGGATTTCGTCACCCTGTCCAAATTTTACGGCAAGTACAAGGAAGCCCTTCA
ACTGGAACTCATCAACAGCCCCGCCGGCCTCAGCCGCCACATCTGCGAACCCGCCCTCAACCGCCCCGGGCTGGCGATCG
CCGGCTTCTACTCCTACTTTGCCAACAAACGTATCCAGGTTTTCGGCTCCGCGGAGCTGGCCTATCTTCAAAAACTGCCG
GAAGGCATGCGCAAATCTCGCATTCAGCGCATGTTCCGGTGCGAGGTGCCGGGCATCGTCTTCTCCCGTGACAAAATTCC
CCCCCGGGAAATCGTGGAGCTGGCGGATGAAGCCGGCGTCTGCGTCTTCCGCACGAGCCTGGTGACCATGAAATTCGTCA
ACTCAGCCACCATCATTCTGGAAAACGAATTCGCGGAAAGCGTCACCCTGCACGGCTGCATGGTGGACGTGCGCGGAGTG
GGCGTCCTCATCCGCGGCAAGAGCGGCGTGGGGAAGAGTGAAACGGCCCTGGGCCTGATTGAACGCGGCGCGGCCCTCGT
GGCGGACGACATGGTGTACGTGCGCAACGTGGGCGGAGAACTGGTGGCCAGCGCTCCGGAAATGAGCCGCGGCTTCATGG
AGGTACGCGGCCTGGGCATCGTCAACATCACCACCCTTTTCGGCCTGAAATCCATCCGCCACAACAAGCGTCTGGACCTC
ATCGTCACCCTCATTCCCGCCAAGGACCAGGAAGAGCTGGACAGGCTTGGCCTGGAGCGGGAGGGGCTGGACGTCCTGGG
GGAAAAAGTGCTCCATGTTCAGCTTTCCGTGGCTCCCGGCAGGGATATTGCCAGGCTGGTGGAAGTAGCCGCCATGGACT
ATCATCTCAAGGACATGGGCATCGACATGGCCGGGGAGTTCAACCGCCGCCTCATGTCAAACTTCCAATCCTCCGAAAAC
TAG

Upstream 100 bases:

>100_bases
ATGCCGGAACGGGCCTTTTTTCAAAAAATGGAGCCCGCACATGGCGCCGGGAACAATATTTGATTGCTCTCGCGTGTGTT
TTGTTCCTTTATATAGGATT

Downstream 100 bases:

>100_bases
GACTGACAAAAAACTCTTGGAAAAAAACTTTAATTAGTGTACTTACCGTTGTAGCAACCGTTATCACCCCTTACTTCAAA
TTCCATGGTCACCAAGGAAC

Product: HPr kinase

Products: NA

Alternate protein names: HPrK/P; HPr kinase/phosphatase; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MFSKSKVKKVDFVTLSKFYGKYKEALQLELINSPAGLSRHICEPALNRPGLAIAGFYSYFANKRIQVFGSAELAYLQKLP
EGMRKSRIQRMFRCEVPGIVFSRDKIPPREIVELADEAGVCVFRTSLVTMKFVNSATIILENEFAESVTLHGCMVDVRGV
GVLIRGKSGVGKSETALGLIERGAALVADDMVYVRNVGGELVASAPEMSRGFMEVRGLGIVNITTLFGLKSIRHNKRLDL
IVTLIPAKDQEELDRLGLEREGLDVLGEKVLHVQLSVAPGRDIARLVEVAAMDYHLKDMGIDMAGEFNRRLMSNFQSSEN

Sequences:

>Translated_320_residues
MFSKSKVKKVDFVTLSKFYGKYKEALQLELINSPAGLSRHICEPALNRPGLAIAGFYSYFANKRIQVFGSAELAYLQKLP
EGMRKSRIQRMFRCEVPGIVFSRDKIPPREIVELADEAGVCVFRTSLVTMKFVNSATIILENEFAESVTLHGCMVDVRGV
GVLIRGKSGVGKSETALGLIERGAALVADDMVYVRNVGGELVASAPEMSRGFMEVRGLGIVNITTLFGLKSIRHNKRLDL
IVTLIPAKDQEELDRLGLEREGLDVLGEKVLHVQLSVAPGRDIARLVEVAAMDYHLKDMGIDMAGEFNRRLMSNFQSSEN
>Mature_320_residues
MFSKSKVKKVDFVTLSKFYGKYKEALQLELINSPAGLSRHICEPALNRPGLAIAGFYSYFANKRIQVFGSAELAYLQKLP
EGMRKSRIQRMFRCEVPGIVFSRDKIPPREIVELADEAGVCVFRTSLVTMKFVNSATIILENEFAESVTLHGCMVDVRGV
GVLIRGKSGVGKSETALGLIERGAALVADDMVYVRNVGGELVASAPEMSRGFMEVRGLGIVNITTLFGLKSIRHNKRLDL
IVTLIPAKDQEELDRLGLEREGLDVLGEKVLHVQLSVAPGRDIARLVEVAAMDYHLKDMGIDMAGEFNRRLMSNFQSSEN

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of 'Ser-46' in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorgani

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35413; Mature: 35413

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSKSKVKKVDFVTLSKFYGKYKEALQLELINSPAGLSRHICEPALNRPGLAIAGFYSYF
CCCCHHCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHCCCCCCEEHHHHHHHH
ANKRIQVFGSAELAYLQKLPEGMRKSRIQRMFRCEVPGIVFSRDKIPPREIVELADEAGV
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCE
CVFRTSLVTMKFVNSATIILENEFAESVTLHGCMVDVRGVGVLIRGKSGVGKSETALGLI
EEEHHHHHHHHHHCCEEEEEECCHHHHEEEEHEEEEECCEEEEEECCCCCCCCHHHHHHH
ERGAALVADDMVYVRNVGGELVASAPEMSRGFMEVRGLGIVNITTLFGLKSIRHNKRLDL
HCCCHHHHHCCCEEHHCCCHHEECCCHHHCCHHHHHCCCEEEHHHHHHHHHHHCCCCEEE
IVTLIPAKDQEELDRLGLEREGLDVLGEKVLHVQLSVAPGRDIARLVEVAAMDYHLKDMG
EEEEECCCCHHHHHHCCCCCCCHHHHCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
IDMAGEFNRRLMSNFQSSEN
CCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFSKSKVKKVDFVTLSKFYGKYKEALQLELINSPAGLSRHICEPALNRPGLAIAGFYSYF
CCCCHHCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHCCCCCCEEHHHHHHHH
ANKRIQVFGSAELAYLQKLPEGMRKSRIQRMFRCEVPGIVFSRDKIPPREIVELADEAGV
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCE
CVFRTSLVTMKFVNSATIILENEFAESVTLHGCMVDVRGVGVLIRGKSGVGKSETALGLI
EEEHHHHHHHHHHCCEEEEEECCHHHHEEEEHEEEEECCEEEEEECCCCCCCCHHHHHHH
ERGAALVADDMVYVRNVGGELVASAPEMSRGFMEVRGLGIVNITTLFGLKSIRHNKRLDL
HCCCHHHHHCCCEEHHCCCHHEECCCHHHCCHHHHHCCCEEEHHHHHHHHHHHCCCCEEE
IVTLIPAKDQEELDRLGLEREGLDVLGEKVLHVQLSVAPGRDIARLVEVAAMDYHLKDMG
EEEEECCCCHHHHHHCCCCCCCHHHHCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
IDMAGEFNRRLMSNFQSSEN
CCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10714994; 12359880 [H]