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The map label for this gene is trpB [H]

Identifier: 187736187

GI number: 187736187

Start: 2065567

End: 2066790

Strand: Reverse

Name: trpB [H]

Synonym: Amuc_1700

Alternate gene names: 187736187

Gene position: 2066790-2065567 (Counterclockwise)

Preceding gene: 187736188

Following gene: 187736186

Centisome position: 77.58

GC content: 56.62

Gene sequence:

>1224_bases
ATGGATCTCCATACTTATTTACGCAATTTTCCAGACGCCCAGGGCCGTTTTGGCGAATACGGCGGCGTTTACCTGCCGGA
CGAGCTGGTTCCCGCTTTTGAAGAAATTACGGAAGCCTACCAGACGATAGCCCACTCCGCCCAGTTCATTAATGAATTGC
GGCGCATCCGCAAACAGTTTCAGGGACGTCCCACCCCAGTTTACCACTGCGAACGCCTTTCCCGCCACCTGGGCACCTCT
CAAATTTACCTGAAGAGGGAAGATTTGAACCATACAGGCGCCCATAAGCTCAACCATTGCATGGGGGAAGGCCTTCTGGC
CAAATACATGGGCAAGAAGCGCATTATCGCGGAAACGGGCGCAGGACAGCATGGCGTGGCGCTGGCTACAGCCGCCGCCT
TCTTCGGCCTGGAATGCGAAATTCACATGGGAGCGGTAGATATTGCCAAGCAGGCTCCGAATGTCACCCGCATGAAAATC
CTGGGTGCCAAGGTGGTTCCTGTCACGCACGGCCTCCAAAGCTTGAAGGAAGCTGTGGATTCCGCCTTTGAATCTTACCT
GAACAGTTATCAGGATTCCATTTACTGCATCGGTTCCGTGGTAGGCCCCCACCCTTTCCCGCAAATGGTGCGCGATTTCC
AAATGTGCATCGGCGTGGAAGCCCGGGAACAATTCCTGGAAATGACGGGACTTCTGCCGGACGCCGTCTGCGCCTGCGTG
GGCGGCGGCAGCAATTCCATGGGCATGTTTACCGCCTTCCTGGGAGACCCGCTGGATATCTATGGCGTAGAACCCCTCGG
CAAAGGTCCCAGGCTTGGGGATCATTCCGCCTCCATCACCTATGGACGCAAGGGCGTCCTGCACGGTTTTGAAAGCATCA
TGCTCCAGGATGAAGACGGTAATCCGGGACCGGTTCATTCCGTAGCCAGCGGCCTGGATTATCCTTCCGTAGGGCCGGAA
CACGCCTATCTGCACGACATCGGCCGCGTTAACTATGTCACCGCCACAGACGAGGAAGCCGTGGACGCCTTCTTCAAACT
TTCCCGTTACGAGGGGATCATTCCCGCTCTGGAAAGCTCCCACGCTATCGCGTATGCCATGAAGTGGGCACGGGAAAACA
GAGGAGGCGCCATTCTGGTAAACTGCTCCGGCCGCGGAGACAAGGATGTGGATTACGTCGTGGAGCATTACGGCTATGGG
GAAGACCACCAGTTCCCCGCCTGA

Upstream 100 bases:

>100_bases
TTTTTCTTTCCTTTCTTTTTTAAAAGGGCTTCCGGGGAGATTGTTTTTGCCTGAACTGTGGCATCGTGCTAAATACTGGC
AGTCACGAACGCAACAGACC

Downstream 100 bases:

>100_bases
TTGCCCTGCCTTTCCTCATTTTCGGCGTATGAAGGGTGCCGTCATCCTTCATACGCCATCCTTACGCAAGGCTCTTAACG
CAGCCACGCCACCTTTCCAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MDLHTYLRNFPDAQGRFGEYGGVYLPDELVPAFEEITEAYQTIAHSAQFINELRRIRKQFQGRPTPVYHCERLSRHLGTS
QIYLKREDLNHTGAHKLNHCMGEGLLAKYMGKKRIIAETGAGQHGVALATAAAFFGLECEIHMGAVDIAKQAPNVTRMKI
LGAKVVPVTHGLQSLKEAVDSAFESYLNSYQDSIYCIGSVVGPHPFPQMVRDFQMCIGVEAREQFLEMTGLLPDAVCACV
GGGSNSMGMFTAFLGDPLDIYGVEPLGKGPRLGDHSASITYGRKGVLHGFESIMLQDEDGNPGPVHSVASGLDYPSVGPE
HAYLHDIGRVNYVTATDEEAVDAFFKLSRYEGIIPALESSHAIAYAMKWARENRGGAILVNCSGRGDKDVDYVVEHYGYG
EDHQFPA

Sequences:

>Translated_407_residues
MDLHTYLRNFPDAQGRFGEYGGVYLPDELVPAFEEITEAYQTIAHSAQFINELRRIRKQFQGRPTPVYHCERLSRHLGTS
QIYLKREDLNHTGAHKLNHCMGEGLLAKYMGKKRIIAETGAGQHGVALATAAAFFGLECEIHMGAVDIAKQAPNVTRMKI
LGAKVVPVTHGLQSLKEAVDSAFESYLNSYQDSIYCIGSVVGPHPFPQMVRDFQMCIGVEAREQFLEMTGLLPDAVCACV
GGGSNSMGMFTAFLGDPLDIYGVEPLGKGPRLGDHSASITYGRKGVLHGFESIMLQDEDGNPGPVHSVASGLDYPSVGPE
HAYLHDIGRVNYVTATDEEAVDAFFKLSRYEGIIPALESSHAIAYAMKWARENRGGAILVNCSGRGDKDVDYVVEHYGYG
EDHQFPA
>Mature_407_residues
MDLHTYLRNFPDAQGRFGEYGGVYLPDELVPAFEEITEAYQTIAHSAQFINELRRIRKQFQGRPTPVYHCERLSRHLGTS
QIYLKREDLNHTGAHKLNHCMGEGLLAKYMGKKRIIAETGAGQHGVALATAAAFFGLECEIHMGAVDIAKQAPNVTRMKI
LGAKVVPVTHGLQSLKEAVDSAFESYLNSYQDSIYCIGSVVGPHPFPQMVRDFQMCIGVEAREQFLEMTGLLPDAVCACV
GGGSNSMGMFTAFLGDPLDIYGVEPLGKGPRLGDHSASITYGRKGVLHGFESIMLQDEDGNPGPVHSVASGLDYPSVGPE
HAYLHDIGRVNYVTATDEEAVDAFFKLSRYEGIIPALESSHAIAYAMKWARENRGGAILVNCSGRGDKDVDYVVEHYGYG
EDHQFPA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=377, Percent_Identity=49.6021220159151, Blast_Score=384, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=49.3472584856397, Blast_Score=371, Evalue=1e-104,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44604; Mature: 44604

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHTYLRNFPDAQGRFGEYGGVYLPDELVPAFEEITEAYQTIAHSAQFINELRRIRKQF
CCHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRPTPVYHCERLSRHLGTSQIYLKREDLNHTGAHKLNHCMGEGLLAKYMGKKRIIAETG
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCHHHHHHCCCCEEEEECC
AGQHGVALATAAAFFGLECEIHMGAVDIAKQAPNVTRMKILGAKVVPVTHGLQSLKEAVD
CCCCCHHHHHHHHHHCCEEEEECCHHHHHHCCCCCEEEEECCCEECHHHHHHHHHHHHHH
SAFESYLNSYQDSIYCIGSVVGPHPFPQMVRDFQMCIGVEAREQFLEMTGLLPDAVCACV
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHH
GGGSNSMGMFTAFLGDPLDIYGVEPLGKGPRLGDHSASITYGRKGVLHGFESIMLQDEDG
CCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEECCCHHHHHHHHHHEEECCCC
NPGPVHSVASGLDYPSVGPEHAYLHDIGRVNYVTATDEEAVDAFFKLSRYEGIIPALESS
CCCCHHHHHCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCC
HAIAYAMKWARENRGGAILVNCSGRGDKDVDYVVEHYGYGEDHQFPA
CHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDLHTYLRNFPDAQGRFGEYGGVYLPDELVPAFEEITEAYQTIAHSAQFINELRRIRKQF
CCHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGRPTPVYHCERLSRHLGTSQIYLKREDLNHTGAHKLNHCMGEGLLAKYMGKKRIIAETG
CCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCHHHHHHCCCCEEEEECC
AGQHGVALATAAAFFGLECEIHMGAVDIAKQAPNVTRMKILGAKVVPVTHGLQSLKEAVD
CCCCCHHHHHHHHHHCCEEEEECCHHHHHHCCCCCEEEEECCCEECHHHHHHHHHHHHHH
SAFESYLNSYQDSIYCIGSVVGPHPFPQMVRDFQMCIGVEAREQFLEMTGLLPDAVCACV
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHH
GGGSNSMGMFTAFLGDPLDIYGVEPLGKGPRLGDHSASITYGRKGVLHGFESIMLQDEDG
CCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEECCCHHHHHHHHHHEEECCCC
NPGPVHSVASGLDYPSVGPEHAYLHDIGRVNYVTATDEEAVDAFFKLSRYEGIIPALESS
CCCCHHHHHCCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCC
HAIAYAMKWARENRGGAILVNCSGRGDKDVDYVVEHYGYGEDHQFPA
CHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA