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The map label for this gene is oxaA [H]

Identifier: 187735748

GI number: 187735748

Start: 1512812

End: 1514698

Strand: Reverse

Name: oxaA [H]

Synonym: Amuc_1254

Alternate gene names: 187735748

Gene position: 1514698-1512812 (Counterclockwise)

Preceding gene: 187735749

Following gene: 187735746

Centisome position: 56.86

GC content: 55.11

Gene sequence:

>1887_bases
ATGGATCGCACAGCATGGATCATCATAGGCATCTGCGCCGCCCTTCTGGGCCTGAATATTTACATGGGCAACAATAAAAA
GGCTGAAACCGCCCCCATTCCCGCACCGCAGGCGGCTGCCGCCGCAGCCAATGCCCCGGTTGCCGGCGTCCGCCCCGGAG
CCGGAACCTCCGCCCCGGAACAGGCCTCCGTCAACAAAGCCCTTGAAGAAGACAAAACCGCCCCGATCACTCTGGTAGCC
ACGCAGGAAGTGAACGGGAGGCAGGAACCCTTCATCACTTACACGTTCAACCGCATAGGGGGTTCCATCGGTACGGTTAC
CCTGCACAACGATATTGTGGACTCCCAAAAAGTCGCGGACCATAATATCACGATTAACGAAGCCCAGCAACGGGGCATCG
GAGAACTCGTTTTCAACATGGACGCCACCCAGGATCCTTCCTATGACAACACCGTGTATAAGGAAGCGAAACGCACGGCG
GACTCCGTAACCCTGGAAGGCTATGACCCCGCACGGCAGCTTTTCATCTCAAAAACGTACACCCTGCACCCCGTCAAAAA
TCTGGAAGGGGAAGTATTGCCCGGCAGCAAATATCTCATTCGCCTGACCGTCTCCCTGCTCAATAAATCTCCCAATGTCC
AGGATCTGCGCTACATGGGCATCTTCGGCGGGAGCGCCTATCCTATCGCCAAAAGCGAACCAAAAGATACCTACACCCAT
TTCTTTTACCATGCAGACGGCTCCCTGGAACAGGAAGTGCCTTCCTATTTCACAGGCGGCTTTTTCAGCAGTGCCAAGGC
CCGCGTCCTGGAAGGCCCTCTCCAGGACCTGACTTATGCCGGCGTCATGAGCCAGTATTACGCCACCATCCTTCTTCCCC
AGGACCAGTCCAGGGGGTCCACCGTGTACGCCACCCGCCAGGAATTTCCTTTGACGCATGAAGGCAACACCCTGGTGCCC
GGCGTCACCGTGGCCATGGGAATCCCCAATCTGACCATGGCCCCCAATGAAATCAAGACGCTCACCTACGATATTTACAC
CGGCCCCAAATTCAACGCCTACCTGCGTGACCTGAATCTTTCCTATCCCGCCATCAGCGATATCATGGCATACGGCTGGC
TCGTATTTCTGAGCGTTCCGATGAACTGGCTGCTCAACCTCTTCCACGGATGGTTCGGCAACTGGGGCGTGGCCATCATC
TGCATGACCATCGTTGTCCGTGCTCTCATCTGGCCGCTGCACAAAAAATCCTATATGGCCATGAAACGCATGTCCCTGGT
TCAGCCGGAGATGGTCAAACTCAAGGAGAAATATCCGGACGACCCTCAGAAGGTGAACATGGAAATGATGAAGCTGTACC
AGAAATACGGCATCAACCCGGCCAGCGGCTGCGTCCCCATGCTTATCCAGATTCCCATTTTCTTTGCCTTTTACCGTGTG
CTCCAGTATTCCGCAGAACTGAGGGGGCAGCCCTTCTGCCTGTGGATGACGGACCTTTCCCTGCCTGATACCGTGGGCCA
CCTGTTCGGCGTTCCAATCAATATTCTGCCTCTCATCATGGCCGTAACCATGATTATCCAGATGAGGATGACGCCTCAGG
CGGGGGAACGCTCCCAGCGCATTATTATGAACCTGATGCCTGTGATGTTCTTCCTGTTCTGTTACAATTTCGCTTCCGCC
CTGGCCCTGTACTGGACCACGCAGAATTTGATCTCCATAGGACAAACGGCCCTTATCCGCCGCTTGCCCATGCCCGTGCT
TTCCCCCGCCAAAAAGAAAAAGTCGGGCTTTTTCCAAAAGATGATGGAGCAGCAGCGTGCGGCCCTGGAAGAACAGCAGC
GCAAAGCTAAAGGCCGCAACATGCGCAATATAACGCCTAAAAAGTAG

Upstream 100 bases:

>100_bases
GATCAGGTTATGATCCCGTGCCCCCGGCGCGCCACCCACGCTGAACAATTACCTTTCTTTCCCTTTCCTTTCACCAACTC
CAATCAAGCTATATCACATT

Downstream 100 bases:

>100_bases
GAATCCCTGCTCTGCCTTCCGTCTCCGCAAGTGCGTCCGCCCCCGCGGCCGCACTTTTTCATGGAAAGGCGCAGGAAAAA
ATATTCTGCCGGCGCAAGCC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MDRTAWIIIGICAALLGLNIYMGNNKKAETAPIPAPQAAAAAANAPVAGVRPGAGTSAPEQASVNKALEEDKTAPITLVA
TQEVNGRQEPFITYTFNRIGGSIGTVTLHNDIVDSQKVADHNITINEAQQRGIGELVFNMDATQDPSYDNTVYKEAKRTA
DSVTLEGYDPARQLFISKTYTLHPVKNLEGEVLPGSKYLIRLTVSLLNKSPNVQDLRYMGIFGGSAYPIAKSEPKDTYTH
FFYHADGSLEQEVPSYFTGGFFSSAKARVLEGPLQDLTYAGVMSQYYATILLPQDQSRGSTVYATRQEFPLTHEGNTLVP
GVTVAMGIPNLTMAPNEIKTLTYDIYTGPKFNAYLRDLNLSYPAISDIMAYGWLVFLSVPMNWLLNLFHGWFGNWGVAII
CMTIVVRALIWPLHKKSYMAMKRMSLVQPEMVKLKEKYPDDPQKVNMEMMKLYQKYGINPASGCVPMLIQIPIFFAFYRV
LQYSAELRGQPFCLWMTDLSLPDTVGHLFGVPINILPLIMAVTMIIQMRMTPQAGERSQRIIMNLMPVMFFLFCYNFASA
LALYWTTQNLISIGQTALIRRLPMPVLSPAKKKKSGFFQKMMEQQRAALEEQQRKAKGRNMRNITPKK

Sequences:

>Translated_628_residues
MDRTAWIIIGICAALLGLNIYMGNNKKAETAPIPAPQAAAAAANAPVAGVRPGAGTSAPEQASVNKALEEDKTAPITLVA
TQEVNGRQEPFITYTFNRIGGSIGTVTLHNDIVDSQKVADHNITINEAQQRGIGELVFNMDATQDPSYDNTVYKEAKRTA
DSVTLEGYDPARQLFISKTYTLHPVKNLEGEVLPGSKYLIRLTVSLLNKSPNVQDLRYMGIFGGSAYPIAKSEPKDTYTH
FFYHADGSLEQEVPSYFTGGFFSSAKARVLEGPLQDLTYAGVMSQYYATILLPQDQSRGSTVYATRQEFPLTHEGNTLVP
GVTVAMGIPNLTMAPNEIKTLTYDIYTGPKFNAYLRDLNLSYPAISDIMAYGWLVFLSVPMNWLLNLFHGWFGNWGVAII
CMTIVVRALIWPLHKKSYMAMKRMSLVQPEMVKLKEKYPDDPQKVNMEMMKLYQKYGINPASGCVPMLIQIPIFFAFYRV
LQYSAELRGQPFCLWMTDLSLPDTVGHLFGVPINILPLIMAVTMIIQMRMTPQAGERSQRIIMNLMPVMFFLFCYNFASA
LALYWTTQNLISIGQTALIRRLPMPVLSPAKKKKSGFFQKMMEQQRAALEEQQRKAKGRNMRNITPKK
>Mature_628_residues
MDRTAWIIIGICAALLGLNIYMGNNKKAETAPIPAPQAAAAAANAPVAGVRPGAGTSAPEQASVNKALEEDKTAPITLVA
TQEVNGRQEPFITYTFNRIGGSIGTVTLHNDIVDSQKVADHNITINEAQQRGIGELVFNMDATQDPSYDNTVYKEAKRTA
DSVTLEGYDPARQLFISKTYTLHPVKNLEGEVLPGSKYLIRLTVSLLNKSPNVQDLRYMGIFGGSAYPIAKSEPKDTYTH
FFYHADGSLEQEVPSYFTGGFFSSAKARVLEGPLQDLTYAGVMSQYYATILLPQDQSRGSTVYATRQEFPLTHEGNTLVP
GVTVAMGIPNLTMAPNEIKTLTYDIYTGPKFNAYLRDLNLSYPAISDIMAYGWLVFLSVPMNWLLNLFHGWFGNWGVAII
CMTIVVRALIWPLHKKSYMAMKRMSLVQPEMVKLKEKYPDDPQKVNMEMMKLYQKYGINPASGCVPMLIQIPIFFAFYRV
LQYSAELRGQPFCLWMTDLSLPDTVGHLFGVPINILPLIMAVTMIIQMRMTPQAGERSQRIIMNLMPVMFFLFCYNFASA
LALYWTTQNLISIGQTALIRRLPMPVLSPAKKKKSGFFQKMMEQQRAALEEQQRKAKGRNMRNITPKK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=268, Percent_Identity=25, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790140, Length=321, Percent_Identity=34.8909657320872, Blast_Score=190, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321002, Length=250, Percent_Identity=26.4, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662345, Length=236, Percent_Identity=27.5423728813559, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356443, Length=236, Percent_Identity=27.5423728813559, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 70184; Mature: 70184

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTAWIIIGICAALLGLNIYMGNNKKAETAPIPAPQAAAAAANAPVAGVRPGAGTSAPE
CCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
QASVNKALEEDKTAPITLVATQEVNGRQEPFITYTFNRIGGSIGTVTLHNDIVDSQKVAD
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEHHHHCCCEEEEEEECCCCCCHHHCC
HNITINEAQQRGIGELVFNMDATQDPSYDNTVYKEAKRTADSVTLEGYDPARQLFISKTY
CCCEECHHHHCCCHHEEEECCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHCCE
TLHPVKNLEGEVLPGSKYLIRLTVSLLNKSPNVQDLRYMGIFGGSAYPIAKSEPKDTYTH
EECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
FFYHADGSLEQEVPSYFTGGFFSSAKARVLEGPLQDLTYAGVMSQYYATILLPQDQSRGS
EEEECCCCHHHHHHHHHCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCCCC
TVYATRQEFPLTHEGNTLVPGVTVAMGIPNLTMAPNEIKTLTYDIYTGPKFNAYLRDLNL
EEEEECCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCC
SYPAISDIMAYGWLVFLSVPMNWLLNLFHGWFGNWGVAIICMTIVVRALIWPLHKKSYMA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKRMSLVQPEMVKLKEKYPDDPQKVNMEMMKLYQKYGINPASGCVPMLIQIPIFFAFYRV
HHHHHHCCHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LQYSAELRGQPFCLWMTDLSLPDTVGHLFGVPINILPLIMAVTMIIQMRMTPQAGERSQR
HHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IIMNLMPVMFFLFCYNFASALALYWTTQNLISIGQTALIRRLPMPVLSPAKKKKSGFFQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
MMEQQRAALEEQQRKAKGRNMRNITPKK
HHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDRTAWIIIGICAALLGLNIYMGNNKKAETAPIPAPQAAAAAANAPVAGVRPGAGTSAPE
CCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
QASVNKALEEDKTAPITLVATQEVNGRQEPFITYTFNRIGGSIGTVTLHNDIVDSQKVAD
HHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEHHHHCCCEEEEEEECCCCCCHHHCC
HNITINEAQQRGIGELVFNMDATQDPSYDNTVYKEAKRTADSVTLEGYDPARQLFISKTY
CCCEECHHHHCCCHHEEEECCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHCCE
TLHPVKNLEGEVLPGSKYLIRLTVSLLNKSPNVQDLRYMGIFGGSAYPIAKSEPKDTYTH
EECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
FFYHADGSLEQEVPSYFTGGFFSSAKARVLEGPLQDLTYAGVMSQYYATILLPQDQSRGS
EEEECCCCHHHHHHHHHCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCCCC
TVYATRQEFPLTHEGNTLVPGVTVAMGIPNLTMAPNEIKTLTYDIYTGPKFNAYLRDLNL
EEEEECCCCCCCCCCCEECCCEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCC
SYPAISDIMAYGWLVFLSVPMNWLLNLFHGWFGNWGVAIICMTIVVRALIWPLHKKSYMA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKRMSLVQPEMVKLKEKYPDDPQKVNMEMMKLYQKYGINPASGCVPMLIQIPIFFAFYRV
HHHHHHCCHHHHHHHHHCCCCHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LQYSAELRGQPFCLWMTDLSLPDTVGHLFGVPINILPLIMAVTMIIQMRMTPQAGERSQR
HHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IIMNLMPVMFFLFCYNFASALALYWTTQNLISIGQTALIRRLPMPVLSPAKKKKSGFFQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
MMEQQRAALEEQQRKAKGRNMRNITPKK
HHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA