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The map label for this gene is yccK [H]

Identifier: 187735654

GI number: 187735654

Start: 1391587

End: 1392735

Strand: Direct

Name: yccK [H]

Synonym: Amuc_1160

Alternate gene names: 187735654

Gene position: 1391587-1392735 (Clockwise)

Preceding gene: 187735653

Following gene: 187735656

Centisome position: 52.23

GC content: 58.05

Gene sequence:

>1149_bases
ATGAGCATGTATAAACACTATTCTGACGGCCGCCGCCGCTTTCTCAAAATGTCCGCCTTGTTCGGTACGTCTGCGCTGAT
TTCTCCGGCCATTGCCCGGGCAGAGGGCGGGGGTGCCGATTCTCCGGAAAACGGCGGCTTTGCCGCCTCCCGGAGCCGGA
CGCTTGGCAAGGGCTCCTGTGCCTTGGAAGCTTCTCCCCTTGGCTTCGGAGTCATGGGAATGACCTACAACCGCAGCCAG
TCTCCCTCGCGTGAGCAGTGCATCCGGCTTCTTCATGAGGCCGTGGAGCGCGGAGTGACTCTTTTTGATACGGCCATCAT
CTACGGCCCCCTGAGCAATGAACTTCTGGCCGGGGAAGCTCTTTCCCCCTTCAGGGGGAAGATCAGCGTCACTACCAAGT
TCGGGCACGAAGTTATTAACGGAAAGGGGACGGGCCGCCAGGACAGCCGCCCGGAAACCATCCGGCGCTACTGCGACGAG
TCGCTGCGCCGTTTGAAGGTGGACGCTATTGAATTATTCTACCAGCACCGCTTTGATCCCAGGATTCCCGTTGAAGATGT
AGCGGGAACCATCTCCGAACTGGTCAAGGAAGGCAAGGTGCGGCGCTGGGGCATGTGCGAAGTCACTCCCGGTACAATTC
GCAGGGCCCACGCCGTCCATCCCCTGACAGCCATTCAGAGTGAGTACCATCTCATGCACCGGGATGTTGAAAACAATGGC
GTTCTGGATGTCTGCCGTGAACTGGGTATAGGCTTTGTCCCCTACAGCCCGCTCAACAGGGGATTCCTGGGGGGCTGCAT
CAATGAATACACGCAATTTGACCCGAACAACGACAACCGCCAGACCCTGCCGCGTTTCACGCCGGAGGCCATGAGAGCCA
ATATGCGTATTGTCAATATTCTGCAACAGTTTGGGAGGACGCGCGGCATGACTTCCTCCCAGGTTGCCCTGGGATGGCTG
CTGCAAAAGGCTCCTTATATCGTACCCATTCCCGGCACCACTAAACTGTCCCATCTGGAAGAAAACCTGCACACGCTTGA
TTTTACCTGCTCTCCGCAGGAGTGGGCGGAACTGGAGAACGCCGTAGCCGCCACACCCGTGACCGGAGCACGCTACAACG
CGGAACAGCAAAGGCAAGTAGGGCATTGA

Upstream 100 bases:

>100_bases
GGCGCTTCCTGAGATAAATTGTTGTATTCCCTTGTTGACTTCCAGTTGGTGGAACCCATATGCTCGGATGATATATCAAA
ATTTCAACCATCAACGTTTA

Downstream 100 bases:

>100_bases
CCCGATTTGTTTGCCGGGATAAACGGCAATCGCAACGGCGGCCTCCGCAGAACGTTCGTCAGGCGTTCCATACTATCCGG
AATTCCTTGTTGATTCCGTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSMYKHYSDGRRRFLKMSALFGTSALISPAIARAEGGGADSPENGGFAASRSRTLGKGSCALEASPLGFGVMGMTYNRSQ
SPSREQCIRLLHEAVERGVTLFDTAIIYGPLSNELLAGEALSPFRGKISVTTKFGHEVINGKGTGRQDSRPETIRRYCDE
SLRRLKVDAIELFYQHRFDPRIPVEDVAGTISELVKEGKVRRWGMCEVTPGTIRRAHAVHPLTAIQSEYHLMHRDVENNG
VLDVCRELGIGFVPYSPLNRGFLGGCINEYTQFDPNNDNRQTLPRFTPEAMRANMRIVNILQQFGRTRGMTSSQVALGWL
LQKAPYIVPIPGTTKLSHLEENLHTLDFTCSPQEWAELENAVAATPVTGARYNAEQQRQVGH

Sequences:

>Translated_382_residues
MSMYKHYSDGRRRFLKMSALFGTSALISPAIARAEGGGADSPENGGFAASRSRTLGKGSCALEASPLGFGVMGMTYNRSQ
SPSREQCIRLLHEAVERGVTLFDTAIIYGPLSNELLAGEALSPFRGKISVTTKFGHEVINGKGTGRQDSRPETIRRYCDE
SLRRLKVDAIELFYQHRFDPRIPVEDVAGTISELVKEGKVRRWGMCEVTPGTIRRAHAVHPLTAIQSEYHLMHRDVENNG
VLDVCRELGIGFVPYSPLNRGFLGGCINEYTQFDPNNDNRQTLPRFTPEAMRANMRIVNILQQFGRTRGMTSSQVALGWL
LQKAPYIVPIPGTTKLSHLEENLHTLDFTCSPQEWAELENAVAATPVTGARYNAEQQRQVGH
>Mature_381_residues
SMYKHYSDGRRRFLKMSALFGTSALISPAIARAEGGGADSPENGGFAASRSRTLGKGSCALEASPLGFGVMGMTYNRSQS
PSREQCIRLLHEAVERGVTLFDTAIIYGPLSNELLAGEALSPFRGKISVTTKFGHEVINGKGTGRQDSRPETIRRYCDES
LRRLKVDAIELFYQHRFDPRIPVEDVAGTISELVKEGKVRRWGMCEVTPGTIRRAHAVHPLTAIQSEYHLMHRDVENNGV
LDVCRELGIGFVPYSPLNRGFLGGCINEYTQFDPNNDNRQTLPRFTPEAMRANMRIVNILQQFGRTRGMTSSQVALGWLL
QKAPYIVPIPGTTKLSHLEENLHTLDFTCSPQEWAELENAVAATPVTGARYNAEQQRQVGH

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436962, Length=308, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=27.0967741935484, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI27436969, Length=305, Percent_Identity=25.2459016393443, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4504825, Length=305, Percent_Identity=25.2459016393443, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI27436971, Length=352, Percent_Identity=23.5795454545455, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=30.4615384615385, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1789375, Length=306, Percent_Identity=27.1241830065359, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1787674, Length=320, Percent_Identity=26.875, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=29.9363057324841, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788081, Length=301, Percent_Identity=22.5913621262458, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789199, Length=337, Percent_Identity=25.8160237388724, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI48994888, Length=303, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=332, Percent_Identity=25.9036144578313, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=337, Percent_Identity=27.299703264095, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=24.7491638795987, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=24.4094488188976, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=348, Percent_Identity=22.9885057471264, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=20.7100591715976, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42396; Mature: 42265

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMYKHYSDGRRRFLKMSALFGTSALISPAIARAEGGGADSPENGGFAASRSRTLGKGSC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ALEASPLGFGVMGMTYNRSQSPSREQCIRLLHEAVERGVTLFDTAIIYGPLSNELLAGEA
EEECCCCCEEEECEEECCCCCCCHHHHHHHHHHHHHCCCEEEEHHEEECCCCCCHHCCCC
LSPFRGKISVTTKFGHEVINGKGTGRQDSRPETIRRYCDESLRRLKVDAIELFYQHRFDP
CCCCCCEEEEEEHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIPVEDVAGTISELVKEGKVRRWGMCEVTPGTIRRAHAVHPLTAIQSEYHLMHRDVENNG
CCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
VLDVCRELGIGFVPYSPLNRGFLGGCINEYTQFDPNNDNRQTLPRFTPEAMRANMRIVNI
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LQQFGRTRGMTSSQVALGWLLQKAPYIVPIPGTTKLSHLEENLHTLDFTCSPQEWAELEN
HHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHEEEEECCHHHHHHHHH
AVAATPVTGARYNAEQQRQVGH
HHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
SMYKHYSDGRRRFLKMSALFGTSALISPAIARAEGGGADSPENGGFAASRSRTLGKGSC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ALEASPLGFGVMGMTYNRSQSPSREQCIRLLHEAVERGVTLFDTAIIYGPLSNELLAGEA
EEECCCCCEEEECEEECCCCCCCHHHHHHHHHHHHHCCCEEEEHHEEECCCCCCHHCCCC
LSPFRGKISVTTKFGHEVINGKGTGRQDSRPETIRRYCDESLRRLKVDAIELFYQHRFDP
CCCCCCEEEEEEHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIPVEDVAGTISELVKEGKVRRWGMCEVTPGTIRRAHAVHPLTAIQSEYHLMHRDVENNG
CCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
VLDVCRELGIGFVPYSPLNRGFLGGCINEYTQFDPNNDNRQTLPRFTPEAMRANMRIVNI
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LQQFGRTRGMTSSQVALGWLLQKAPYIVPIPGTTKLSHLEENLHTLDFTCSPQEWAELEN
HHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHEEEEECCHHHHHHHHH
AVAATPVTGARYNAEQQRQVGH
HHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]