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The map label for this gene is nusG [H]

Identifier: 187735541

GI number: 187735541

Start: 1248961

End: 1249530

Strand: Reverse

Name: nusG [H]

Synonym: Amuc_1046

Alternate gene names: 187735541

Gene position: 1249530-1248961 (Counterclockwise)

Preceding gene: 187735542

Following gene: 187735540

Centisome position: 46.9

GC content: 58.07

Gene sequence:

>570_bases
ATGCCCAGTACCCCAGAGCCTCACGAACAATGGTATGTCCTTCACGTCCTCTCCGGACAGGAAAACAGCGTTCGTGACCG
CATCATCCGCAAGGCGAAGGACGCCGAGCTTTCCGACTTCATTTACCGGGTGGAAGTCCCCACGGAACTTATTTCCGAAG
TGCGCAACGGCAAAAAAACGGAACGTCACAGCAAACTCTTTCCCGGGTATGTTTATGCCAACATGTACCTGCTGGAAGCG
GACGGCACCCTGAACAAGGACCTTTGGTACTTTATCCAGCAAATTGACGGTGTCATCAGCATTGCCGGCTCCCGCAACGC
CCCCCTCCCCATGCGCAAGCGCGAGGTGGAAGACCTTCTGCCCCTGTTGGATGCGGAAGCCGTCGCCGCCCGTCCCAAGG
TGGAATTCGCCGTCGGCGACCCTGTGCGCGTGTGCGAAGGCCCGTTCCAGAGCCAGGAAGGCACCATCGAAGAAATCGAC
CCGGAAAAGGGCAAGCTGCGTGTCAGTGTCTCCATTTTTGGCCGCGCCACGCCTGTGGACCTGGAATACTGGCAGGTGGA
AAAAGCCTGA

Upstream 100 bases:

>100_bases
GCGCGTTTGTTGCATCGTTCGACATCTTTCTTCACAGCGTGGTCAACTATCTCATCCAGTTGGCAATCTAGTTTTACTCT
CCCCACTTCTTTCTCCGATC

Downstream 100 bases:

>100_bases
ATCTTCTTTGCGTCTCCCCCCATCAGTCCCCTTCCCGTTTATTTTCTCCGCTAACAAAGCAAAACCATGGCAAAAGAAAT
AACCAAAATCATCAAGCTCC

Product: NusG antitermination factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MPSTPEPHEQWYVLHVLSGQENSVRDRIIRKAKDAELSDFIYRVEVPTELISEVRNGKKTERHSKLFPGYVYANMYLLEA
DGTLNKDLWYFIQQIDGVISIAGSRNAPLPMRKREVEDLLPLLDAEAVAARPKVEFAVGDPVRVCEGPFQSQEGTIEEID
PEKGKLRVSVSIFGRATPVDLEYWQVEKA

Sequences:

>Translated_189_residues
MPSTPEPHEQWYVLHVLSGQENSVRDRIIRKAKDAELSDFIYRVEVPTELISEVRNGKKTERHSKLFPGYVYANMYLLEA
DGTLNKDLWYFIQQIDGVISIAGSRNAPLPMRKREVEDLLPLLDAEAVAARPKVEFAVGDPVRVCEGPFQSQEGTIEEID
PEKGKLRVSVSIFGRATPVDLEYWQVEKA
>Mature_188_residues
PSTPEPHEQWYVLHVLSGQENSVRDRIIRKAKDAELSDFIYRVEVPTELISEVRNGKKTERHSKLFPGYVYANMYLLEAD
GTLNKDLWYFIQQIDGVISIAGSRNAPLPMRKREVEDLLPLLDAEAVAARPKVEFAVGDPVRVCEGPFQSQEGTIEEIDP
EKGKLRVSVSIFGRATPVDLEYWQVEKA

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=184, Percent_Identity=38.5869565217391, Blast_Score=130, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 21485; Mature: 21353

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTPEPHEQWYVLHVLSGQENSVRDRIIRKAKDAELSDFIYRVEVPTELISEVRNGKKT
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHEEEEEECCHHHHHHHHCCCCH
ERHSKLFPGYVYANMYLLEADGTLNKDLWYFIQQIDGVISIAGSRNAPLPMRKREVEDLL
HHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHH
PLLDAEAVAARPKVEFAVGDPVRVCEGPFQSQEGTIEEIDPEKGKLRVSVSIFGRATPVD
HHHCCHHHHCCCCEEEEECCCHHHCCCCCCCCCCCHHHCCCCCCEEEEEEEEECCCCCCC
LEYWQVEKA
CEEEEEECC
>Mature Secondary Structure 
PSTPEPHEQWYVLHVLSGQENSVRDRIIRKAKDAELSDFIYRVEVPTELISEVRNGKKT
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHEEEEEECCHHHHHHHHCCCCH
ERHSKLFPGYVYANMYLLEADGTLNKDLWYFIQQIDGVISIAGSRNAPLPMRKREVEDLL
HHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHH
PLLDAEAVAARPKVEFAVGDPVRVCEGPFQSQEGTIEEIDPEKGKLRVSVSIFGRATPVD
HHHCCHHHHCCCCEEEEECCCHHHCCCCCCCCCCCHHHCCCCCCEEEEEEEEECCCCCCC
LEYWQVEKA
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]