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The map label for this gene is pkn1 [H]

Identifier: 187735490

GI number: 187735490

Start: 1185518

End: 1186723

Strand: Reverse

Name: pkn1 [H]

Synonym: Amuc_0993

Alternate gene names: 187735490

Gene position: 1186723-1185518 (Counterclockwise)

Preceding gene: 187735491

Following gene: 187735488

Centisome position: 44.54

GC content: 61.36

Gene sequence:

>1206_bases
ATGCGCGGCATTTTCCTTGTTTCCTGCTTTCTGGGAGGAAGCGTCCTGCTGGCCGGGTGCCGGGAAGAAAATAATTCCCC
CCGCCCGGCCACGGAAGATGCCGCGCGCATTACCAGCGCACGCCAGTGGGGAGAAAGCCGATCCGCGCTGCAAAAACGGG
AACTGGACCGCGCTGCCGGTCCTGCCCTTCCCATTCCGGATGACCTGCCGTCCCGGGAGCTGGTCGGCACGACGCGCCAA
ATCCATCAGCTCATTGAAGCTTCCGGAAATCCGGCACGTTTTGAATCCTACACGGAAACGGTTCCCGCGGCGGGAGCTTC
CCTGCGCATGGTCGCCATACCGGGAGGAACGTTCCTCATGGGGAGTACCGCGGAAGAGCCGCACCGGAAACCGGACGAAG
GACCGCAGCATAAAGTGAGCATCTCTCCCTTCTGGATCTCGGAAACGGAAATCCCCTGGGAACTTTATACGGCCTTCATG
GAAAACGGGCGTCCGCGCGCCAAGGACGGTCAGCTTCTGGAGGAACAGCCGGATGACGAACTGTGGGACTCCGTTACGCA
GCCTACCGCCCCCTACACCGCCATGAACCTGGGCATGGGTCACGGCTATGAACACGGTCTGCCCGCCATCTCCATGTCCC
ACCACGCCGCCAGCAAATTCTGCGAATGGCTGAGCGCCCAGACCGGGCATTACTACCGCCTGCCCACGGAGGCGGAATGG
GAATACGCCTGCCGGGCCGGCTCCCCCGGCGCCTATTCTTACGGAAACGGGGAAGCCTCTCTGGACCAGTACGCCTGGTA
CTGGAACAACTCCAATGACCGCTACCAGAAAACAGGCTCTAAAAAACCAAATAAGTGGGGACTCCGGGACATGCACGGAA
ATGTGGCGGAATGGGTTTTGGACTCTTACGTTCCGGATGCCTACGGCAAACGGAGCGGCTTGCCCGCGAAAGACCCCCTG
GTCATCATCCCCGGCGCCCCTCACATCGTTCGCGGCGGTTCGTGGGAAGACGACCCGGACAGCCTGAGAAGCGCTGCGCG
CCGCGCCAGCACCCCTGCCTGGAACCGTCAGGATCCTCAAAACCCTAAAAGCATCTGGTACCTGACGGACGGAGGCATGA
TCGGGTTCCGCGTGGTGCGCCCCATGAACATTCCGGACGTTATGACGATGCACCGCCTCTGGAATTTCTCCAAGGGGGAG
CCGTAA

Upstream 100 bases:

>100_bases
CGGCCTTCCTTGCCTCTGACGATGCCCGTTACATCACCGGGCAGGTCATTGCCTGCGACGGAGGCATGACGATGTAGGGC
ATTCCGGTTTTCACCATTCC

Downstream 100 bases:

>100_bases
AGAACAACCCTTCATGATCATTGCATTAAGAACGGAACATGTCACGAGAGAAGCGCTCTGGAACTATTTCGTCCCCGGCT
GCAATGAACATTACCTGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGESRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQ
IHQLIEASGNPARFESYTETVPAAGASLRMVAIPGGTFLMGSTAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFM
ENGRPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEW
EYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPL
VIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGE
P

Sequences:

>Translated_401_residues
MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGESRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQ
IHQLIEASGNPARFESYTETVPAAGASLRMVAIPGGTFLMGSTAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFM
ENGRPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEW
EYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPL
VIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGE
P
>Mature_401_residues
MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGESRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQ
IHQLIEASGNPARFESYTETVPAAGASLRMVAIPGGTFLMGSTAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFM
ENGRPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEW
EYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPL
VIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGE
P

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=280, Percent_Identity=26.7857142857143, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194248088, Length=290, Percent_Identity=25.5172413793103, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 44572; Mature: 44572

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGESRSALQKRELDRAAG
CCCEEEEHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAAGASLRMVAIPGGTFLM
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEE
GSTAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGRPRAKDGQLLEEQPDDE
CCCCCCCCCCCCCCCCCEEEECEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCHH
LWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEW
HHHHHCCCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEECCCCCCC
EYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVL
HHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCHHHCCCHHHHHH
DSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQ
HHHCCCHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC
NPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGEP
CCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGESRSALQKRELDRAAG
CCCEEEEHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAAGASLRMVAIPGGTFLM
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEE
GSTAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGRPRAKDGQLLEEQPDDE
CCCCCCCCCCCCCCCCCEEEECEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCHH
LWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEW
HHHHHCCCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEECCCCCCC
EYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVL
HHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCHHHCCCHHHHHH
DSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQ
HHHCCCHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC
NPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGEP
CCCEEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]