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The map label for this gene is dtd

Identifier: 187735479

GI number: 187735479

Start: 1167149

End: 1167601

Strand: Direct

Name: dtd

Synonym: Amuc_0978

Alternate gene names: 187735479

Gene position: 1167149-1167601 (Clockwise)

Preceding gene: 187735478

Following gene: 187735485

Centisome position: 43.81

GC content: 57.62

Gene sequence:

>453_bases
GTGAGGCTGGTTATTCAGCGTGTCAGTAAGGCCGCCGTTCATATCGGCGGTGTTTGTGCGGGGGCCGTGGGGCCCGGTCT
GCTGATTCTGGCGGGCATTGAAGAGGCGGATACGGAAGAAGATGTGCGCTGGCTCGCCAACAAGGCGGCGGCCATGCGCA
TTTTTTCCGACGCGGACGGAAAGATGAATCTTTCCGTAAGGGAAGTGAGTGGAAGCGTGTTGGTGGTGAGCCAGTTTACG
CTGCATGCCTCCACCCGGAAAGGGAACAGGCCCTCTTTCATCCGCGCCGCGAGGCCTGAGCGGGCCATTCCCCTGTATGA
GCTGTTTAAGAAGGAATTGGCGTCTTTGCTGGAAGGCAGGGTGGAAAGCGGCGAATTCGGCGCGGATATGCAGGTTTCCC
TGATTAACGACGGCCCGGTGACTATTTTCATGGATTCCAGGAAAAGGGAATGA

Upstream 100 bases:

>100_bases
CGCCTGGGTTTTATCTGAGCCGGCAGGACTGCAATGAACTGGCCATGCTGACCAGGCCGGGAACGAAGGTGACTATCCTG
AGGGGGAAAGGAGAGGAACC

Downstream 100 bases:

>100_bases
GAGAAAGGATCTTATATATTTAACTTTGCCCCGGTTTCCTGCTTTCTCTCTATCTCCATATAAACATAGAAAAATATTGC
CGATAGATCTGTTGCTCCTC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRLVIQRVSKAAVHIGGVCAGAVGPGLLILAGIEEADTEEDVRWLANKAAAMRIFSDADGKMNLSVREVSGSVLVVSQFT
LHASTRKGNRPSFIRAARPERAIPLYELFKKELASLLEGRVESGEFGADMQVSLINDGPVTIFMDSRKRE

Sequences:

>Translated_150_residues
MRLVIQRVSKAAVHIGGVCAGAVGPGLLILAGIEEADTEEDVRWLANKAAAMRIFSDADGKMNLSVREVSGSVLVVSQFT
LHASTRKGNRPSFIRAARPERAIPLYELFKKELASLLEGRVESGEFGADMQVSLINDGPVTIFMDSRKRE
>Mature_150_residues
MRLVIQRVSKAAVHIGGVCAGAVGPGLLILAGIEEADTEEDVRWLANKAAAMRIFSDADGKMNLSVREVSGSVLVVSQFT
LHASTRKGNRPSFIRAARPERAIPLYELFKKELASLLEGRVESGEFGADMQVSLINDGPVTIFMDSRKRE

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=39.1891891891892, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=50.6944444444444, Blast_Score=143, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=37.0860927152318, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.2162162162162, Blast_Score=109, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=41.4965986394558, Blast_Score=113, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_AKKM8 (B2UQS5)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877591.1
- ProteinModelPortal:   B2UQS5
- SMR:   B2UQS5
- GeneID:   6274163
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0978
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16283; Mature: 16283

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVIQRVSKAAVHIGGVCAGAVGPGLLILAGIEEADTEEDVRWLANKAAAMRIFSDADG
CHHHHHHHHHHHHHHCCEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLSVREVSGSVLVVSQFTLHASTRKGNRPSFIRAARPERAIPLYELFKKELASLLEGR
EEEEEEEECCCCEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCC
VESGEFGADMQVSLINDGPVTIFMDSRKRE
CCCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRLVIQRVSKAAVHIGGVCAGAVGPGLLILAGIEEADTEEDVRWLANKAAAMRIFSDADG
CHHHHHHHHHHHHHHCCEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLSVREVSGSVLVVSQFTLHASTRKGNRPSFIRAARPERAIPLYELFKKELASLLEGR
EEEEEEEECCCCEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCC
VESGEFGADMQVSLINDGPVTIFMDSRKRE
CCCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA