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The map label for this gene is kdpE [H]

Identifier: 187735330

GI number: 187735330

Start: 978169

End: 978867

Strand: Direct

Name: kdpE [H]

Synonym: Amuc_0828

Alternate gene names: 187735330

Gene position: 978169-978867 (Clockwise)

Preceding gene: 187735329

Following gene: 187735331

Centisome position: 36.72

GC content: 57.37

Gene sequence:

>699_bases
ATGAGCAACTTTCCTGCAGATATCCTGATTATTGACGATGAACGGCAGATACGCCGTCTTCTGAACCTGACGCTGACCGG
CGCAGGCTACCATGTCCGCGAGTGTGAAAACGGGCAGCTTGGCTTGAGTGAGACCGCTCTGAAGCGGCCGGATGCCATTA
TTCTGGATCTGGGGCTTCCGGACATTAACGGCTTGGAAGTGCTGAAACAGCTTCGGGAGTGGACTCAGGTTCCTATCCTG
ATTCTAACGGCTTGGGACAGGGAGGATGAAAAGGTGGATGCCTTGGATGCCGGGGCGGATGATTACTTGACCAAGCCGTT
CAGCGGCCGTGAATTGCTGGCGCGCCTGCGCGTGATGCTTCGGCGCAATCGTCCGGACCGTGAGCCGTCCGTATTCCGGC
TGGGTCCCATTGTCGTGGATCTGAGTTCCCGGCGCGTGGAGAAGGGGAAAGAGGAAATTCATTTAACCTCCAAAGAGTAC
GGAATTCTGCGCCTGCTTCTGCTCCATCAGGGCAAGGTGATGACCCACCGCCAGCTGCTCCGTGAAATTTGGGGTCCCCA
GCATGAGGAGGACACGCACTACCTGCGGGTGCACATTGCCCACCTGCGCCAAAAGCTGGGGGATTCCGATCCGGAAAACC
GCATTATTCGCGCGGAATCCGGCCTGGGTTACAGAATTGTGGCGGATGGAGCCGAGTAG

Upstream 100 bases:

>100_bases
GCCGTCTCCCTGGTTCCCGTTTCCGCCGGAACATGTTTCCGGCTTGTCCTTCCCCTGGTGGAGCACGATAGTGTTCCTGA
AGAGTAATTCCTCCTGCCTC

Downstream 100 bases:

>100_bases
CCCTTGTCCCAGTTTTACTGGGCTGGAAAAAATAGCGGCACATTATCTGCGGCAGCCGGAAAATATATTTTTTCATAACG
GTTGGAGAATGTGGCTTAAC

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSNFPADILIIDDERQIRRLLNLTLTGAGYHVRECENGQLGLSETALKRPDAIILDLGLPDINGLEVLKQLREWTQVPIL
ILTAWDREDEKVDALDAGADDYLTKPFSGRELLARLRVMLRRNRPDREPSVFRLGPIVVDLSSRRVEKGKEEIHLTSKEY
GILRLLLLHQGKVMTHRQLLREIWGPQHEEDTHYLRVHIAHLRQKLGDSDPENRIIRAESGLGYRIVADGAE

Sequences:

>Translated_232_residues
MSNFPADILIIDDERQIRRLLNLTLTGAGYHVRECENGQLGLSETALKRPDAIILDLGLPDINGLEVLKQLREWTQVPIL
ILTAWDREDEKVDALDAGADDYLTKPFSGRELLARLRVMLRRNRPDREPSVFRLGPIVVDLSSRRVEKGKEEIHLTSKEY
GILRLLLLHQGKVMTHRQLLREIWGPQHEEDTHYLRVHIAHLRQKLGDSDPENRIIRAESGLGYRIVADGAE
>Mature_231_residues
SNFPADILIIDDERQIRRLLNLTLTGAGYHVRECENGQLGLSETALKRPDAIILDLGLPDINGLEVLKQLREWTQVPILI
LTAWDREDEKVDALDAGADDYLTKPFSGRELLARLRVMLRRNRPDREPSVFRLGPIVVDLSSRRVEKGKEEIHLTSKEYG
ILRLLLLHQGKVMTHRQLLREIWGPQHEEDTHYLRVHIAHLRQKLGDSDPENRIIRAESGLGYRIVADGAE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=47.9820627802691, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=39.1111111111111, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=38.2882882882883, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=31.981981981982, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=36.322869955157, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=33.7552742616034, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=34.4036697247706, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=32.3275862068966, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=34.0909090909091, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=31.140350877193, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=31.1965811965812, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.0429184549356, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=35.8490566037736, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790299, Length=135, Percent_Identity=32.5925925925926, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=31.6239316239316, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26596; Mature: 26465

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFPADILIIDDERQIRRLLNLTLTGAGYHVRECENGQLGLSETALKRPDAIILDLGLP
CCCCCCEEEEECCHHHHHHHHHEEECCCCEEEEECCCCCCCCHHHHHCCCCEEEEECCCC
DINGLEVLKQLREWTQVPILILTAWDREDEKVDALDAGADDYLTKPFSGRELLARLRVML
CCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCCCHHHCCCCCCHHHHHHHHHHH
RRNRPDREPSVFRLGPIVVDLSSRRVEKGKEEIHLTSKEYGILRLLLLHQGKVMTHRQLL
HCCCCCCCCCEEEECCEEEECCHHHHHCCHHHEEECCCHHHHHHHHHHHCCCHHHHHHHH
REIWGPQHEEDTHYLRVHIAHLRQKLGDSDPENRIIRAESGLGYRIVADGAE
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEECCCC
>Mature Secondary Structure 
SNFPADILIIDDERQIRRLLNLTLTGAGYHVRECENGQLGLSETALKRPDAIILDLGLP
CCCCCEEEEECCHHHHHHHHHEEECCCCEEEEECCCCCCCCHHHHHCCCCEEEEECCCC
DINGLEVLKQLREWTQVPILILTAWDREDEKVDALDAGADDYLTKPFSGRELLARLRVML
CCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCCCHHHCCCCCCHHHHHHHHHHH
RRNRPDREPSVFRLGPIVVDLSSRRVEKGKEEIHLTSKEYGILRLLLLHQGKVMTHRQLL
HCCCCCCCCCEEEECCEEEECCHHHHHCCHHHEEECCCHHHHHHHHHHHCCCHHHHHHHH
REIWGPQHEEDTHYLRVHIAHLRQKLGDSDPENRIIRAESGLGYRIVADGAE
HHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]