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The map label for this gene is murG [H]

Identifier: 187735165

GI number: 187735165

Start: 774741

End: 775865

Strand: Direct

Name: murG [H]

Synonym: Amuc_0659

Alternate gene names: 187735165

Gene position: 774741-775865 (Clockwise)

Preceding gene: 187735164

Following gene: 187735166

Centisome position: 29.08

GC content: 59.82

Gene sequence:

>1125_bases
ATGACTGAACCCTCTCTCAAACATCCCTCCCTGAACATCGTGATCGCCTGCGGCGGCACGGGGGGGCACCTTTTTCCCGG
CATAGCCGTAGCCCAGGAACTTAAAAAGCGCGGCCACCGCGTCACGCTCCTCATCTCCCAGAAGAAAGTGGACGCCCAGG
CCAGCAAAAATTACGGGGATCTTGACTTCCGCACCATTGAGGCCATCGCGATGCCCAAAATCCCATCCCTGTCCCTGCTG
GGGTTCGGCGTCAGGCTGTACAAAGCCATCCGTTTCAGCCGCCATCTTCTGGACGAGGTGGAAGCGGACGTCGTCATCGG
CATGGGAGGATTCACTTCATTCCCTCCCGTTTACGCCGCCCACCGCAAGGGAATCCGCACCTACGTGCACGATTCCAACG
CGCTGCCCGGAAAGGCCAACCGCATGACCGCCAAATGCTGCACGAACGTGCTGCTGGGCATTGAGGAAGCCAGGCACTAC
TTCAATCCCGCCAAATGCATTGTCACCGGCACTCCGGTACGCCAGGAAATGGTGGCCCGGAAAGACAAAAACGAAGCCAG
GGCGGAGCTCAACCTGCCCCAGGACCGCCGCGTGGCCCTGGTAATGGGCGGTTCCCAGGGGGCCAGGAATCTGAATTCCC
TAGTCATTGAAGCCGCCCGGCAATGCGCAGACCTGTGCGACTTTCTCATCATCACCGGCTCCGCGGACTTTGCACGCGTC
AGCCAGCTGACGGCGGACATGCCCCACGTGCACGTCATTGAATTCTGTTCCGCCATGGCTGCCGCTTATGCCGCAGCGGA
TGTGGTCATTTCCCGTTCCGGGGCGTCCAGCCTTACGGAACTGGCCCATATGGGGAAGGCCGCCCTGCTGGTTCCCTACC
CCTTCGCCGCAGACGATCACCAGGCACACAACGCACGCGTTTTCGCGGCCCACGGCGCGGCGCGCATGATGCGTGAAAAC
ACCCTCACGCCGGACGATATTGCGGCTTTCCTGAATGAAGTACTCAAGGATTCCTCCCTGCTGGCCTCCATGAATGAATG
TGCTTTACGTCTGGACATGCCTGATGCAGTATCCCGCATCGCCAATGTCATTGAACATACGGACCATGCAGCCTCCCATG
ATTGA

Upstream 100 bases:

>100_bases
CCGCCCTGGGCATGCTCACCAGCATCCAGAGGTTTTCCACCGGCGCCCAGCCCAATTGTGAAATCACCCGCAAAGACGAA
CGCTCCATTGACGTAAGATT

Downstream 100 bases:

>100_bases
AACCTTACGCAAAAGACTGACAGACAGGGAACACCCGGCACGCCTACATCTCATCGGGGTAGCCGGGTCAGGCATGTCCG
GCCTGGCGCTCATGCTGATG

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTEPSLKHPSLNIVIACGGTGGHLFPGIAVAQELKKRGHRVTLLISQKKVDAQASKNYGDLDFRTIEAIAMPKIPSLSLL
GFGVRLYKAIRFSRHLLDEVEADVVIGMGGFTSFPPVYAAHRKGIRTYVHDSNALPGKANRMTAKCCTNVLLGIEEARHY
FNPAKCIVTGTPVRQEMVARKDKNEARAELNLPQDRRVALVMGGSQGARNLNSLVIEAARQCADLCDFLIITGSADFARV
SQLTADMPHVHVIEFCSAMAAAYAAADVVISRSGASSLTELAHMGKAALLVPYPFAADDHQAHNARVFAAHGAARMMREN
TLTPDDIAAFLNEVLKDSSLLASMNECALRLDMPDAVSRIANVIEHTDHAASHD

Sequences:

>Translated_374_residues
MTEPSLKHPSLNIVIACGGTGGHLFPGIAVAQELKKRGHRVTLLISQKKVDAQASKNYGDLDFRTIEAIAMPKIPSLSLL
GFGVRLYKAIRFSRHLLDEVEADVVIGMGGFTSFPPVYAAHRKGIRTYVHDSNALPGKANRMTAKCCTNVLLGIEEARHY
FNPAKCIVTGTPVRQEMVARKDKNEARAELNLPQDRRVALVMGGSQGARNLNSLVIEAARQCADLCDFLIITGSADFARV
SQLTADMPHVHVIEFCSAMAAAYAAADVVISRSGASSLTELAHMGKAALLVPYPFAADDHQAHNARVFAAHGAARMMREN
TLTPDDIAAFLNEVLKDSSLLASMNECALRLDMPDAVSRIANVIEHTDHAASHD
>Mature_373_residues
TEPSLKHPSLNIVIACGGTGGHLFPGIAVAQELKKRGHRVTLLISQKKVDAQASKNYGDLDFRTIEAIAMPKIPSLSLLG
FGVRLYKAIRFSRHLLDEVEADVVIGMGGFTSFPPVYAAHRKGIRTYVHDSNALPGKANRMTAKCCTNVLLGIEEARHYF
NPAKCIVTGTPVRQEMVARKDKNEARAELNLPQDRRVALVMGGSQGARNLNSLVIEAARQCADLCDFLIITGSADFARVS
QLTADMPHVHVIEFCSAMAAAYAAADVVISRSGASSLTELAHMGKAALLVPYPFAADDHQAHNARVFAAHGAARMMRENT
LTPDDIAAFLNEVLKDSSLLASMNECALRLDMPDAVSRIANVIEHTDHAASHD

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=369, Percent_Identity=34.6883468834688, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 40415; Mature: 40284

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPSLKHPSLNIVIACGGTGGHLFPGIAVAQELKKRGHRVTLLISQKKVDAQASKNYGD
CCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHCCCCCC
LDFRTIEAIAMPKIPSLSLLGFGVRLYKAIRFSRHLLDEVEADVVIGMGGFTSFPPVYAA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHH
HRKGIRTYVHDSNALPGKANRMTAKCCTNVLLGIEEARHYFNPAKCIVTGTPVRQEMVAR
HHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
KDKNEARAELNLPQDRRVALVMGGSQGARNLNSLVIEAARQCADLCDFLIITGSADFARV
CCCCHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHH
SQLTADMPHVHVIEFCSAMAAAYAAADVVISRSGASSLTELAHMGKAALLVPYPFAADDH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCEEEECCCCCCCCC
QAHNARVFAAHGAARMMRENTLTPDDIAAFLNEVLKDSSLLASMNECALRLDMPDAVSRI
CCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEEECCHHHHHHH
ANVIEHTDHAASHD
HHHHHHCCCCCCCC
>Mature Secondary Structure 
TEPSLKHPSLNIVIACGGTGGHLFPGIAVAQELKKRGHRVTLLISQKKVDAQASKNYGD
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHCCCCCC
LDFRTIEAIAMPKIPSLSLLGFGVRLYKAIRFSRHLLDEVEADVVIGMGGFTSFPPVYAA
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHH
HRKGIRTYVHDSNALPGKANRMTAKCCTNVLLGIEEARHYFNPAKCIVTGTPVRQEMVAR
HHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
KDKNEARAELNLPQDRRVALVMGGSQGARNLNSLVIEAARQCADLCDFLIITGSADFARV
CCCCHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHH
SQLTADMPHVHVIEFCSAMAAAYAAADVVISRSGASSLTELAHMGKAALLVPYPFAADDH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCCCEEEECCCCCCCCC
QAHNARVFAAHGAARMMRENTLTPDDIAAFLNEVLKDSSLLASMNECALRLDMPDAVSRI
CCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEEECCHHHHHHH
ANVIEHTDHAASHD
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA