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The map label for this gene is mraY [H]

Identifier: 187735161

GI number: 187735161

Start: 770327

End: 771430

Strand: Direct

Name: mraY [H]

Synonym: Amuc_0655

Alternate gene names: 187735161

Gene position: 770327-771430 (Clockwise)

Preceding gene: 187735160

Following gene: 187735162

Centisome position: 28.92

GC content: 60.6

Gene sequence:

>1104_bases
ATGCATTCCGTTATTGAACAGTTCAGCCCCTCGGGGGCATTTGCAGAACCGGCAGGGAGGGCCCTCCTGGCCTGCCTGGT
TTCCTTTGCCCTGACCATGATATTCGCCCCGCGGGTCATCCGGGCGCTGATTTCCCTGAAAATCGGCCAGCCCATCAGGA
CGGCAGAAGAGGTGCACAAGCTGGCGGAACTCCACGGGGCCAAGGCGGGAACGCCCACCATGGGCGGCGTGCTGATCGTA
GGGTCCATGACGGCGGCTACCCTGTTGTGCGCCAGAATGGGCAATCCCTTTATCATTGCCTGCCTGATCGTCACCCTGGC
GCTGGGCCTGCTGGGATTCCGGGACGATTACCTGAAGGTGGCGAAAAAAACCTCGGACGGCATTTCCGCACGTAAAAAAC
TCCTCGTCCAGTTCCTGGCCGGCCTGGCCGGCGTCACCTTCCTGTACCTGTACCCGGAAGGCAATCCCCGCGTGGAACTT
CACGACTACATATCCTCCCTGTTCATTCCGTTCTATGGCCAGGTGAACCTGCCATGGTTCGTTTATATTCCTTTCGGCGT
CGTGGTGGTCATGTCCGCCTCCAATGCGGTGAACCTGACAGACGGCCTGGACGGCCTCGCCTCCGGCTGCTCCGTCGCCA
CGGGCATTACTTACGCCATCATTGCCGTCCTCTGCGGAAGCTGGCTGACGGCTGATTCCCTGGATATTCCCTTCCACCCC
GGCGCGGGAGAAATCAGCGTCTTCATGATGGCCCTGGTAGGGGCCTGTCTGGGCTTCCTCTGGCACAATTGCTACCCGGC
CAGGGTATTTATGGGAGACACCGGCTCCCTGGCCCTGGGCGGAGCGTTCGGCATGGCTGCCGTCTGCACGGCGCAGGAGC
TTCTCTTTATCGTCATCGGGGGCGTCTTCGTCATGGAGGCCGCGTCCGTCGTGCTGCAGGTAGGCAGCTACAAGCTGCGC
CACGGCAAACGCATCTTCGCCATGGCTCCCATCCACCACCATTTTGAACTCAAAGGCTGGAAGGAAACGCAGGTGATTGC
CCGCTTCTGGATGATCAGCCTCCTGCTGGCTTTCCTGGGCCTTTTCCTGATTACCACCGCCTGA

Upstream 100 bases:

>100_bases
GCAGCCATACGGCGCCGGGAGACATCGTCCTCTTCAAAGGCAGCCGCCTCGCCCGGATGGAGCAAGTCATGAACCTCACC
TTTCCGCCACAGTAAATTTT

Downstream 100 bases:

>100_bases
CAAACCACGAACATGCAGCTCAATAACCTCAACATCGCCGTTCTGGGAGCGGGAAGAAGCGGACGCGCCGCGGCGCGCCT
CGCCATAAAGCATGGCGCAC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MHSVIEQFSPSGAFAEPAGRALLACLVSFALTMIFAPRVIRALISLKIGQPIRTAEEVHKLAELHGAKAGTPTMGGVLIV
GSMTAATLLCARMGNPFIIACLIVTLALGLLGFRDDYLKVAKKTSDGISARKKLLVQFLAGLAGVTFLYLYPEGNPRVEL
HDYISSLFIPFYGQVNLPWFVYIPFGVVVVMSASNAVNLTDGLDGLASGCSVATGITYAIIAVLCGSWLTADSLDIPFHP
GAGEISVFMMALVGACLGFLWHNCYPARVFMGDTGSLALGGAFGMAAVCTAQELLFIVIGGVFVMEAASVVLQVGSYKLR
HGKRIFAMAPIHHHFELKGWKETQVIARFWMISLLLAFLGLFLITTA

Sequences:

>Translated_367_residues
MHSVIEQFSPSGAFAEPAGRALLACLVSFALTMIFAPRVIRALISLKIGQPIRTAEEVHKLAELHGAKAGTPTMGGVLIV
GSMTAATLLCARMGNPFIIACLIVTLALGLLGFRDDYLKVAKKTSDGISARKKLLVQFLAGLAGVTFLYLYPEGNPRVEL
HDYISSLFIPFYGQVNLPWFVYIPFGVVVVMSASNAVNLTDGLDGLASGCSVATGITYAIIAVLCGSWLTADSLDIPFHP
GAGEISVFMMALVGACLGFLWHNCYPARVFMGDTGSLALGGAFGMAAVCTAQELLFIVIGGVFVMEAASVVLQVGSYKLR
HGKRIFAMAPIHHHFELKGWKETQVIARFWMISLLLAFLGLFLITTA
>Mature_367_residues
MHSVIEQFSPSGAFAEPAGRALLACLVSFALTMIFAPRVIRALISLKIGQPIRTAEEVHKLAELHGAKAGTPTMGGVLIV
GSMTAATLLCARMGNPFIIACLIVTLALGLLGFRDDYLKVAKKTSDGISARKKLLVQFLAGLAGVTFLYLYPEGNPRVEL
HDYISSLFIPFYGQVNLPWFVYIPFGVVVVMSASNAVNLTDGLDGLASGCSVATGITYAIIAVLCGSWLTADSLDIPFHP
GAGEISVFMMALVGACLGFLWHNCYPARVFMGDTGSLALGGAFGMAAVCTAQELLFIVIGGVFVMEAASVVLQVGSYKLR
HGKRIFAMAPIHHHFELKGWKETQVIARFWMISLLLAFLGLFLITTA

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=44.3213296398892, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39222; Mature: 39222

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSVIEQFSPSGAFAEPAGRALLACLVSFALTMIFAPRVIRALISLKIGQPIRTAEEVHK
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LAELHGAKAGTPTMGGVLIVGSMTAATLLCARMGNPFIIACLIVTLALGLLGFRDDYLKV
HHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHH
AKKTSDGISARKKLLVQFLAGLAGVTFLYLYPEGNPRVELHDYISSLFIPFYGQVNLPWF
HHHCCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCCEE
VYIPFGVVVVMSASNAVNLTDGLDGLASGCSVATGITYAIIAVLCGSWLTADSLDIPFHP
EEEHHHHHEEEECCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GAGEISVFMMALVGACLGFLWHNCYPARVFMGDTGSLALGGAFGMAAVCTAQELLFIVIG
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHH
GVFVMEAASVVLQVGSYKLRHGKRIFAMAPIHHHFELKGWKETQVIARFWMISLLLAFLG
HHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHH
LFLITTA
HHHHHCC
>Mature Secondary Structure
MHSVIEQFSPSGAFAEPAGRALLACLVSFALTMIFAPRVIRALISLKIGQPIRTAEEVHK
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LAELHGAKAGTPTMGGVLIVGSMTAATLLCARMGNPFIIACLIVTLALGLLGFRDDYLKV
HHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHH
AKKTSDGISARKKLLVQFLAGLAGVTFLYLYPEGNPRVELHDYISSLFIPFYGQVNLPWF
HHHCCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCCEE
VYIPFGVVVVMSASNAVNLTDGLDGLASGCSVATGITYAIIAVLCGSWLTADSLDIPFHP
EEEHHHHHEEEECCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GAGEISVFMMALVGACLGFLWHNCYPARVFMGDTGSLALGGAFGMAAVCTAQELLFIVIG
CCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHH
GVFVMEAASVVLQVGSYKLRHGKRIFAMAPIHHHFELKGWKETQVIARFWMISLLLAFLG
HHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHH
LFLITTA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA