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The map label for this gene is rsmH [H]

Identifier: 187735156

GI number: 187735156

Start: 763367

End: 764929

Strand: Direct

Name: rsmH [H]

Synonym: Amuc_0650

Alternate gene names: 187735156

Gene position: 763367-764929 (Clockwise)

Preceding gene: 187735155

Following gene: 187735157

Centisome position: 28.65

GC content: 64.17

Gene sequence:

>1563_bases
ATGCCCCCAGACTCCTCCATTACGCCCAATCCCCAGGCACGCCCCTGCGCAACGCTTGCATTGCGCCCGGGCTGGCTTGC
TTCCGGCCTGGGCGTCGGCGCCAGAACCGGGCTGCATGCGGAACTCACGGCTTATTCCATCGTTTTCTGGGGGCACGATG
CCCTTCCGGCGCAGGATATGGTTGCCTGGCAGCAGGAAAAGGCACGCCTCATGGCGGAGATGTCCCTGGCCGGGCAAAAG
GGCGCCTATGGCAAGCTGGGCGCATTGTCTTCCGGCCTGACCCGGGCTTTTGACGACCATATTGAGCTTTCTTTACGCGC
GGGCGCGGGTACGCACGTCCGCACGGAGGAGGTGCAGGCCCTGGCAAACGGGCTCGCGGAAGAAACGTCCTGCCGCGTGC
TGGCGTGGAGCGTCTGCCGCAACCATGTGCATGTGATTGCGGAGCTGACGGAGGAAAAAGGAGTGGATGAACTGGTCTGC
TCCTGGAAGGCGCTGGCCCCCTCCATGAACTGGGAAGACGCGTACCACACGGAAGCCCTGAAAGCCCGGGAAGCCGCGGC
CAGGGTAGACGCCCTGATTTCCGAACTGGGGGATGACGCCGCTGCCGCCGTTGATGCGGAAGCGGACGGGGCAGACTCCG
GAAACGGCTTCCGGCACATTACCGTGCTGCTGCATGAGACGGTGGACATGCTGAAGGCAGGACCCGGCAAATTCATCGTG
GACTGCACGCTTGGCGGAGGCGGCCATACGGAACTTCTGCTGGAGCAGGGAGCCACTGTCTGGGGCATTGACCGCGATGC
GGACGCCCGCCGCGCCGCCATGCTCAGGCTGGCGCGCTTCGGTTCCCGTTTCAAAGTCCTCGCCGGCAACTTCCAGGACG
TGGAAAGCATTCTTTCCCAGCAGGGGGTTTCCCGGGTGGACGGGCTGCTGGCGGACCTGGGCGTTTCCTCCCACCAGCTT
GACACCGCCTCCCGCGGCTTTTCCTTTAGGGAAGACGGCCCTCTGGACATGCGGATGGATACCCGCGCCGCTCTCTCTGC
CCGGAACCTGGTGAATGAGGCCCCGGAAGAAGAAATCGCAAATATCCTCTGGCAATTCGGCGAGGAACGCGCTTCCCGCG
CCATTGCCCGCGCCATGGTGAAAGCCCGTGCCCAGGCACCCATCACCACGACCGCACAGCTTGCCCGCATCGTGGAATCC
GTCCTGCCGCGCAAAGGAAGACAACACCCCGGCACCCGCACGTTCCAGGCCCTGAGAATAGCGGTCAACGGCGAGCTGGA
TGCCCTGGACGCTCTGCTGGATTCCTCCGTGCGTCTGCTCGGGCAGGGGGGGCGCATGGCCGTCATCACCTTCCACAGCC
TGGAAGACCGCAGGGTCAAGCAGTTCTTCGACCTCCGGAGCCGTCCGGAAATAGACCGCCCGGAATGGCCGGCACCCCGT
CCCAACCCGGATTACTGCTTCCGCCCGCTTTCCCGCAAACCCGTCACTGCGGGAGAAGAAGAACTTTCAACCAACCCCCG
TTCCCGCAGCGCCAAGTTGCGCGGCGTGGAAAAAATCATCTGA

Upstream 100 bases:

>100_bases
CGAATTGTGGGAACCCTCTCTCTACGAAGAAGTTTCCCGGCGTGAAAACGCCAGCATCTCCGACATCAACCAATCCTACG
GCATTCTCTAGCTTTCCTTC

Downstream 100 bases:

>100_bases
CCATCTCTCTTCCGCCACCGCCATGAAAAGATTCAAACAGCGTTTCACCGGCCACCAGATCAGCGTGAGCATGATCATGT
GGCTCATTGCCTTCGCCGCC

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MPPDSSITPNPQARPCATLALRPGWLASGLGVGARTGLHAELTAYSIVFWGHDALPAQDMVAWQQEKARLMAEMSLAGQK
GAYGKLGALSSGLTRAFDDHIELSLRAGAGTHVRTEEVQALANGLAEETSCRVLAWSVCRNHVHVIAELTEEKGVDELVC
SWKALAPSMNWEDAYHTEALKAREAAARVDALISELGDDAAAAVDAEADGADSGNGFRHITVLLHETVDMLKAGPGKFIV
DCTLGGGGHTELLLEQGATVWGIDRDADARRAAMLRLARFGSRFKVLAGNFQDVESILSQQGVSRVDGLLADLGVSSHQL
DTASRGFSFREDGPLDMRMDTRAALSARNLVNEAPEEEIANILWQFGEERASRAIARAMVKARAQAPITTTAQLARIVES
VLPRKGRQHPGTRTFQALRIAVNGELDALDALLDSSVRLLGQGGRMAVITFHSLEDRRVKQFFDLRSRPEIDRPEWPAPR
PNPDYCFRPLSRKPVTAGEEELSTNPRSRSAKLRGVEKII

Sequences:

>Translated_520_residues
MPPDSSITPNPQARPCATLALRPGWLASGLGVGARTGLHAELTAYSIVFWGHDALPAQDMVAWQQEKARLMAEMSLAGQK
GAYGKLGALSSGLTRAFDDHIELSLRAGAGTHVRTEEVQALANGLAEETSCRVLAWSVCRNHVHVIAELTEEKGVDELVC
SWKALAPSMNWEDAYHTEALKAREAAARVDALISELGDDAAAAVDAEADGADSGNGFRHITVLLHETVDMLKAGPGKFIV
DCTLGGGGHTELLLEQGATVWGIDRDADARRAAMLRLARFGSRFKVLAGNFQDVESILSQQGVSRVDGLLADLGVSSHQL
DTASRGFSFREDGPLDMRMDTRAALSARNLVNEAPEEEIANILWQFGEERASRAIARAMVKARAQAPITTTAQLARIVES
VLPRKGRQHPGTRTFQALRIAVNGELDALDALLDSSVRLLGQGGRMAVITFHSLEDRRVKQFFDLRSRPEIDRPEWPAPR
PNPDYCFRPLSRKPVTAGEEELSTNPRSRSAKLRGVEKII
>Mature_519_residues
PPDSSITPNPQARPCATLALRPGWLASGLGVGARTGLHAELTAYSIVFWGHDALPAQDMVAWQQEKARLMAEMSLAGQKG
AYGKLGALSSGLTRAFDDHIELSLRAGAGTHVRTEEVQALANGLAEETSCRVLAWSVCRNHVHVIAELTEEKGVDELVCS
WKALAPSMNWEDAYHTEALKAREAAARVDALISELGDDAAAAVDAEADGADSGNGFRHITVLLHETVDMLKAGPGKFIVD
CTLGGGGHTELLLEQGATVWGIDRDADARRAAMLRLARFGSRFKVLAGNFQDVESILSQQGVSRVDGLLADLGVSSHQLD
TASRGFSFREDGPLDMRMDTRAALSARNLVNEAPEEEIANILWQFGEERASRAIARAMVKARAQAPITTTAQLARIVESV
LPRKGRQHPGTRTFQALRIAVNGELDALDALLDSSVRLLGQGGRMAVITFHSLEDRRVKQFFDLRSRPEIDRPEWPAPRP
NPDYCFRPLSRKPVTAGEEELSTNPRSRSAKLRGVEKII

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=399, Percent_Identity=34.8370927318296, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI165377202, Length=249, Percent_Identity=36.144578313253, Blast_Score=139, Evalue=6e-33,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=42.1725239616613, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI62472493, Length=330, Percent_Identity=36.6666666666667, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI28571637, Length=330, Percent_Identity=36.6666666666667, Blast_Score=179, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 56437; Mature: 56305

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPDSSITPNPQARPCATLALRPGWLASGLGVGARTGLHAELTAYSIVFWGHDALPAQDM
CCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHH
VAWQQEKARLMAEMSLAGQKGAYGKLGALSSGLTRAFDDHIELSLRAGAGTHVRTEEVQA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
LANGLAEETSCRVLAWSVCRNHVHVIAELTEEKGVDELVCSWKALAPSMNWEDAYHTEAL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
KAREAAARVDALISELGDDAAAAVDAEADGADSGNGFRHITVLLHETVDMLKAGPGKFIV
HHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCEEE
DCTLGGGGHTELLLEQGATVWGIDRDADARRAAMLRLARFGSRFKVLAGNFQDVESILSQ
EEEECCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
QGVSRVDGLLADLGVSSHQLDTASRGFSFREDGPLDMRMDTRAALSARNLVNEAPEEEIA
CCHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCHHHHH
NILWQFGEERASRAIARAMVKARAQAPITTTAQLARIVESVLPRKGRQHPGTRTFQALRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEEE
AVNGELDALDALLDSSVRLLGQGGRMAVITFHSLEDRRVKQFFDLRSRPEIDRPEWPAPR
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
PNPDYCFRPLSRKPVTAGEEELSTNPRSRSAKLRGVEKII
CCCCHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PPDSSITPNPQARPCATLALRPGWLASGLGVGARTGLHAELTAYSIVFWGHDALPAQDM
CCCCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHH
VAWQQEKARLMAEMSLAGQKGAYGKLGALSSGLTRAFDDHIELSLRAGAGTHVRTEEVQA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
LANGLAEETSCRVLAWSVCRNHVHVIAELTEEKGVDELVCSWKALAPSMNWEDAYHTEAL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
KAREAAARVDALISELGDDAAAAVDAEADGADSGNGFRHITVLLHETVDMLKAGPGKFIV
HHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCEEE
DCTLGGGGHTELLLEQGATVWGIDRDADARRAAMLRLARFGSRFKVLAGNFQDVESILSQ
EEEECCCCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
QGVSRVDGLLADLGVSSHQLDTASRGFSFREDGPLDMRMDTRAALSARNLVNEAPEEEIA
CCHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCHHHHH
NILWQFGEERASRAIARAMVKARAQAPITTTAQLARIVESVLPRKGRQHPGTRTFQALRI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHEEEEEE
AVNGELDALDALLDSSVRLLGQGGRMAVITFHSLEDRRVKQFFDLRSRPEIDRPEWPAPR
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCC
PNPDYCFRPLSRKPVTAGEEELSTNPRSRSAKLRGVEKII
CCCCHHCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA