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The map label for this gene is ttuB [H]

Identifier: 186476011

GI number: 186476011

Start: 1402165

End: 1403439

Strand: Reverse

Name: ttuB [H]

Synonym: Bphy_1252

Alternate gene names: 186476011

Gene position: 1403439-1402165 (Counterclockwise)

Preceding gene: 186476012

Following gene: 186476010

Centisome position: 40.34

GC content: 63.29

Gene sequence:

>1275_bases
ATGCCCTCATCGCTCGCGATTCGCCGTTGGTGGACGATCATGCCGATCGTCTTCATCACCTACAGCCTCGCCTATCTCGA
CCGCGCGAATTACGGCTTCGCGGCCGCCGCCGGCATCAATCAGGATCTCGGCATCAGCAAAGGACTGTCGTCGCTGATCG
GCGCGCTGTTCTTTCTCGGCTACTTTTTCTTCCAGATTCCCGGCGCGATCTACGCCGAACGCAAGAGCGTCAAGAAGCTC
GTGTTCTGGAGCCTCGTTCTGTGGGGCGGCTGCGCGGCGCTGACGGGCGTCGTCAGCAACATTCCATCGTTGATGGTCAT
CCGCTTCCTGCTCGGCGTCGTCGAGGCGGCTGTGATGCCCGCGATGCTGATCTTCATCAGCAACTGGTTCACGAAGCGCG
AGCGCTCGCGTGCCAACACCTTCCTGATTCTCGGCAACCCCGTGACGGTGCTGTGGATGTCGGTCGTGTCGGGCTATCTG
GTGCATTCGTTTGGCTGGCGCCACATGTTCATCGCGGAAGGCTTGCCTGCGATCGTCTGGGCCGTGTGCTGGTGGTTCAT
CGTGAAAGACAAACCGGAGCAGGTGTCGTGGCTGTCGGAGGCGGACAAGAAACAGCTCGCCGACACGCTGCGCGCGGAGC
AGTCCGCCATCAAGCCGGTGCGCAACTACGCCGAGGCGTTCCGCTCGTCGGCCGTGGTCAAGCTGTGCGCGCAGTACTTC
TGCTGGAGCATCGGCGTGTATGGCTTCGTGCTGTGGCTGCCGTCCATCCTGAAGAACGGCTCGTCGCTCGGCATGGTCGA
AACAGGCTGGCTGTCGGCGCTGCCGTATCTGGCTGCGACGATCGCGATGCTCGCGGCGTCGTGGGCGTCGGATAAACTCA
GCAACCGGCGCGCGTTCGTCTGGCCGTTCCTGCTGATCGGCGCGCTGGCTTTCGCGGGCTCGTACGCGCTCGGCTCGACG
CACTTCTGGATGTCGTACGCGCTGCTCGTCGTTGCGGGCGCCGCGATGTACGCGCCCTATGGACCGTTCTTCGCGATCGT
GCCGGAACTGCTACCGAAGAACGTCGCGGGCGGCGCGATGGCGCTGATCAACAGCATGGGCGCGCTCGGCTCGTTCGTCG
GCTCGTATGTGGTCGGCTATCTGAACGGCGCGACGGGCTCGCCTGCTGCATCATATGCGTTCATGAGCGTCGCGTTGCTT
GCCGCCGTAGTCCTGACGCTTGCCGTCAAGCCGCAGCCGATGCAGACTCCGACACTCGCCACTCAAGGAAAGTGA

Upstream 100 bases:

>100_bases
CGAGAACAACAAGATGCACGGCCGCACGCTTGCAACGACGCAAAACGCGCGGCTCGACAGCACATCGACCGACCGCTTCA
GCAAGATACAGGAGACAACC

Downstream 100 bases:

>100_bases
ATCGATGAAGCGAAAGATCGTCGCATACAAGCCGCTGCCGGATGACGTGCTCTCGTATCTTAAGCAGCATGCCGACGTCG
TGCAGGCGGACGCCGCGCAG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MPSSLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERKSVKKL
VFWSLVLWGGCAALTGVVSNIPSLMVIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYL
VHSFGWRHMFIAEGLPAIVWAVCWWFIVKDKPEQVSWLSEADKKQLADTLRAEQSAIKPVRNYAEAFRSSAVVKLCAQYF
CWSIGVYGFVLWLPSILKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKLSNRRAFVWPFLLIGALAFAGSYALGST
HFWMSYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYVVGYLNGATGSPAASYAFMSVALL
AAVVLTLAVKPQPMQTPTLATQGK

Sequences:

>Translated_424_residues
MPSSLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERKSVKKL
VFWSLVLWGGCAALTGVVSNIPSLMVIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYL
VHSFGWRHMFIAEGLPAIVWAVCWWFIVKDKPEQVSWLSEADKKQLADTLRAEQSAIKPVRNYAEAFRSSAVVKLCAQYF
CWSIGVYGFVLWLPSILKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKLSNRRAFVWPFLLIGALAFAGSYALGST
HFWMSYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYVVGYLNGATGSPAASYAFMSVALL
AAVVLTLAVKPQPMQTPTLATQGK
>Mature_423_residues
PSSLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERKSVKKLV
FWSLVLWGGCAALTGVVSNIPSLMVIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYLV
HSFGWRHMFIAEGLPAIVWAVCWWFIVKDKPEQVSWLSEADKKQLADTLRAEQSAIKPVRNYAEAFRSSAVVKLCAQYFC
WSIGVYGFVLWLPSILKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKLSNRRAFVWPFLLIGALAFAGSYALGSTH
FWMSYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYVVGYLNGATGSPAASYAFMSVALLA
AVVLTLAVKPQPMQTPTLATQGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=26.1224489795918, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI9945322, Length=252, Percent_Identity=25, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI154350196, Length=367, Percent_Identity=25.0681198910082, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI9966811, Length=392, Percent_Identity=22.1938775510204, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI148743791, Length=194, Percent_Identity=20.6185567010309, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=369, Percent_Identity=27.9132791327913, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=24.7058823529412, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=23.2346241457859, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789515, Length=428, Percent_Identity=25.2336448598131, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367379, Length=292, Percent_Identity=25, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082404, Length=363, Percent_Identity=24.5179063360882, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=360, Percent_Identity=24.7222222222222, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533554, Length=360, Percent_Identity=24.7222222222222, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17552542, Length=320, Percent_Identity=24.6875, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=439, Percent_Identity=25.5125284738041, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560030, Length=274, Percent_Identity=21.1678832116788, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=255, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554962, Length=332, Percent_Identity=24.0963855421687, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=196, Percent_Identity=26.0204081632653, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=177, Percent_Identity=23.1638418079096, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193205400, Length=238, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=173, Percent_Identity=23.6994219653179, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=400, Percent_Identity=23.75, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=251, Percent_Identity=24.3027888446215, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=251, Percent_Identity=24.3027888446215, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=226, Percent_Identity=24.7787610619469, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550460, Length=409, Percent_Identity=24.9388753056235, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=24.6418338108883, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24655255, Length=360, Percent_Identity=25.8333333333333, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24584153, Length=396, Percent_Identity=22.7272727272727, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573299, Length=310, Percent_Identity=25.1612903225806, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24583789, Length=360, Percent_Identity=21.9444444444444, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573708, Length=260, Percent_Identity=25.7692307692308, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573707, Length=260, Percent_Identity=25.7692307692308, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24655271, Length=413, Percent_Identity=23.728813559322, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20130135, Length=406, Percent_Identity=23.8916256157635, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648416, Length=271, Percent_Identity=25.4612546125461, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356189, Length=271, Percent_Identity=25.4612546125461, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641682, Length=373, Percent_Identity=23.8605898123324, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653727, Length=383, Percent_Identity=25.3263707571802, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI62484226, Length=298, Percent_Identity=25.1677852348993, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19922400, Length=239, Percent_Identity=23.8493723849372, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24654215, Length=239, Percent_Identity=23.8493723849372, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920686, Length=364, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639764, Length=297, Percent_Identity=21.5488215488215, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24658674, Length=282, Percent_Identity=22.3404255319149, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46103; Mature: 45972

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure 
PSSLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]