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The map label for this gene is dnaX2 [H]

Identifier: 183222818

GI number: 183222818

Start: 3598605

End: 3599537

Strand: Direct

Name: dnaX2 [H]

Synonym: LEPBI_I3479

Alternate gene names: 183222818

Gene position: 3598605-3599537 (Clockwise)

Preceding gene: 183222817

Following gene: NA

Centisome position: 99.97

GC content: 38.69

Gene sequence:

>933_bases
ATGGTCGATACTTCGTTTTCATTTGAGCAAGTGTCAGGCCAAGATGTAGCACTGACATACATAAAATCTTTTTTAAAAGA
TCGCTCGAAAATTCCAGGTTCCTTAATTTTTTACGGACCAGATGGGGTGGGGAAGTGGCTTGCCGCAGAACGTTTTGCAC
GACAAATCCTTTGTTTGGAAGGAACCTCTTGCGGTCATTGTGATTCCTGCCGTCAGTTCATGAGAGGAATCCATCCTGAC
TTCATTCAATTCCCAAGACGAAAGAACATTGCAATCGGGAAAGAAAAAGACCCTGAAGAGTTCACCATTCGATGGTTATT
ATCTGCACGGATCCCTTTCAAACCACACACTTCGGATTATCGAATCGTTCTTTTTCCTGAAGCAAATCGAATCAACAATG
AAGCCGAAACCACACTTTTAAAAACATTAGAAGAACCGCCTCCACATACAAAATTCATTCTGATAGTCAATGACCTACAT
AATTTAAAACAAACGATTGTTTCTCGTTCGGTTTGTATTCCTTTCCACTACCTCCCGCAGGATGAAATCAAAAAGATTCG
AAGGAATGAAATCGCGGAAGCAAAATTGTATTATGGTGGTTCCCTCAATCCGTTTGAAATTGCTGATGAATTTTTAGAAG
AGTGGCATGAGAATGTAAGGGAACATTGCCATGATTCCATTTTGCTATTCAAATTAGAAAATTGGGTGAGAGACCAACTC
GGTGAATTTCGTTCGAATAAAGAAGGACTCACTGGAATTGATTTTTTAGAAATGATTTGTTTGTTACTGCTTTATGAATA
CAGACAAAAAAACTTTGAAGCCAATGTGGGTAGGATTGAAGCCATCCTTGACTTTAAAATGAAACTCCATTACGAAATTC
CAGCTCTTGAGTATGTTCTTTTATCCCAACTTTTTTTAAGACTCGCCACATAA

Upstream 100 bases:

>100_bases
CGGACCTGTGACCAAAAAAATCCAATCTATCTTTTTTGAAACTGTACGTGGTGAAGATCCAAAGTATATGAATTGGCTCA
CTCCGGTTTATTAAATTAAA

Downstream 100 bases:

>100_bases
TTAAAAAATAAAAACGAAAGAGAATTGAAACCCTTTCTGAAAGCAAATGGATCTGTATCCATCAATCGATAGGAACCAAT
TATTGACCTTAATTGATCAT

Product: DNA polymerase III subunit gamma/tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVDTSFSFEQVSGQDVALTYIKSFLKDRSKIPGSLIFYGPDGVGKWLAAERFARQILCLEGTSCGHCDSCRQFMRGIHPD
FIQFPRRKNIAIGKEKDPEEFTIRWLLSARIPFKPHTSDYRIVLFPEANRINNEAETTLLKTLEEPPPHTKFILIVNDLH
NLKQTIVSRSVCIPFHYLPQDEIKKIRRNEIAEAKLYYGGSLNPFEIADEFLEEWHENVREHCHDSILLFKLENWVRDQL
GEFRSNKEGLTGIDFLEMICLLLLYEYRQKNFEANVGRIEAILDFKMKLHYEIPALEYVLLSQLFLRLAT

Sequences:

>Translated_310_residues
MVDTSFSFEQVSGQDVALTYIKSFLKDRSKIPGSLIFYGPDGVGKWLAAERFARQILCLEGTSCGHCDSCRQFMRGIHPD
FIQFPRRKNIAIGKEKDPEEFTIRWLLSARIPFKPHTSDYRIVLFPEANRINNEAETTLLKTLEEPPPHTKFILIVNDLH
NLKQTIVSRSVCIPFHYLPQDEIKKIRRNEIAEAKLYYGGSLNPFEIADEFLEEWHENVREHCHDSILLFKLENWVRDQL
GEFRSNKEGLTGIDFLEMICLLLLYEYRQKNFEANVGRIEAILDFKMKLHYEIPALEYVLLSQLFLRLAT
>Mature_310_residues
MVDTSFSFEQVSGQDVALTYIKSFLKDRSKIPGSLIFYGPDGVGKWLAAERFARQILCLEGTSCGHCDSCRQFMRGIHPD
FIQFPRRKNIAIGKEKDPEEFTIRWLLSARIPFKPHTSDYRIVLFPEANRINNEAETTLLKTLEEPPPHTKFILIVNDLH
NLKQTIVSRSVCIPFHYLPQDEIKKIRRNEIAEAKLYYGGSLNPFEIADEFLEEWHENVREHCHDSILLFKLENWVRDQL
GEFRSNKEGLTGIDFLEMICLLLLYEYRQKNFEANVGRIEAILDFKMKLHYEIPALEYVLLSQLFLRLAT

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=184, Percent_Identity=31.5217391304348, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 36202; Mature: 36202

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDTSFSFEQVSGQDVALTYIKSFLKDRSKIPGSLIFYGPDGVGKWLAAERFARQILCLE
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC
GTSCGHCDSCRQFMRGIHPDFIQFPRRKNIAIGKEKDPEEFTIRWLLSARIPFKPHTSDY
CCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
RIVLFPEANRINNEAETTLLKTLEEPPPHTKFILIVNDLHNLKQTIVSRSVCIPFHYLPQ
EEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCCEEEEECCCH
DEIKKIRRNEIAEAKLYYGGSLNPFEIADEFLEEWHENVREHCHDSILLFKLENWVRDQL
HHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
GEFRSNKEGLTGIDFLEMICLLLLYEYRQKNFEANVGRIEAILDFKMKLHYEIPALEYVL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCHHHHHH
LSQLFLRLAT
HHHHHHHHCC
>Mature Secondary Structure
MVDTSFSFEQVSGQDVALTYIKSFLKDRSKIPGSLIFYGPDGVGKWLAAERFARQILCLE
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC
GTSCGHCDSCRQFMRGIHPDFIQFPRRKNIAIGKEKDPEEFTIRWLLSARIPFKPHTSDY
CCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
RIVLFPEANRINNEAETTLLKTLEEPPPHTKFILIVNDLHNLKQTIVSRSVCIPFHYLPQ
EEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCCEEEEECCCH
DEIKKIRRNEIAEAKLYYGGSLNPFEIADEFLEEWHENVREHCHDSILLFKLENWVRDQL
HHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHH
GEFRSNKEGLTGIDFLEMICLLLLYEYRQKNFEANVGRIEAILDFKMKLHYEIPALEYVL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCHHHHHH
LSQLFLRLAT
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]