Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 183222817

GI number: 183222817

Start: 3597675

End: 3598598

Strand: Direct

Name: ilvE [H]

Synonym: LEPBI_I3478

Alternate gene names: 183222817

Gene position: 3597675-3598598 (Clockwise)

Preceding gene: 183222815

Following gene: 183222818

Centisome position: 99.94

GC content: 41.02

Gene sequence:

>924_bases
ATGGCTCAGAATTCATTCCCTTATACATACTTTGAAGGTAAAATTGTTCCTTCCGAAGACGCAAAAGTCAGTGTCCAAAC
CCATGCCTTACAATATGGTACAGGAGTTTTTGGTGGAATCAGAGGTTACTACAACGAAGCCAAACAAAATCTTTATGTCT
TTCGATTGCCAGAACACTGCAAACGACTTGTGAACTCCACAAAGATCATGCAACTTCAAATCAAAATCACTCCGGAAGAA
ATCCAAACCATCATCTTGGATCTACTTCGAAAAAACGAAGCTAAACAAAATGTATACTTAAGACCTTTCATTTATACATC
AGCCTTACAACTTTCGCCTCGATTCCATGATGTGAAAGCTGACATCACTGTGTATGCTCTGAAACTCGATGACTATCTTG
ATACACAAAATGGGCTCACAACCATGGTGTCCTCTTGGCAAAGATTTTCTGATAACCAAATCCCCACTCTTTCGAAAGTG
AGTGGTGGGTATGTGAATTCAGCACTTGCCAAATCGGAAGCGGTTCAAAATGGAATGGATGAAGCCATCTTTCTCGATGC
AAGAGGGTTTGTATCAGAAGGTTCTGCCGAAAATCTTTTTATCGTTCGTGATGGAGTGATCCATACACCAACCATTCCCT
CTTCGATCTTAGAAGGGATCACAAGAAGGAGCATCATTCAAATCGCAAAGGACCTTGGATACCAAGTGATCGAAAGAGAC
ATCGCAAGATCCGAACTGTATATTGCGGATGAATTATTTTTTTCCGGGACTGGTGTGCAGGTAGCTTGGGTGAAAGAAGT
AGATCGCCGAGTGATTGGAAATGGAACCATCGGACCTGTGACCAAAAAAATCCAATCTATCTTTTTTGAAACTGTACGTG
GTGAAGATCCAAAGTATATGAATTGGCTCACTCCGGTTTATTAA

Upstream 100 bases:

>100_bases
GAACGATATCAAAACCATCGGCCTATGCTTCGAGAGAAAAAAAGATAAAATTCATTTTCTAATTTCGAAACTCTTAAAGA
TTGGAAGGATAGGAATCTCA

Downstream 100 bases:

>100_bases
ATTAAAATGGTCGATACTTCGTTTTCATTTGAGCAAGTGTCAGGCCAAGATGTAGCACTGACATACATAAAATCTTTTTT
AAAAGATCGCTCGAAAATTC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAQNSFPYTYFEGKIVPSEDAKVSVQTHALQYGTGVFGGIRGYYNEAKQNLYVFRLPEHCKRLVNSTKIMQLQIKITPEE
IQTIILDLLRKNEAKQNVYLRPFIYTSALQLSPRFHDVKADITVYALKLDDYLDTQNGLTTMVSSWQRFSDNQIPTLSKV
SGGYVNSALAKSEAVQNGMDEAIFLDARGFVSEGSAENLFIVRDGVIHTPTIPSSILEGITRRSIIQIAKDLGYQVIERD
IARSELYIADELFFSGTGVQVAWVKEVDRRVIGNGTIGPVTKKIQSIFFETVRGEDPKYMNWLTPVY

Sequences:

>Translated_307_residues
MAQNSFPYTYFEGKIVPSEDAKVSVQTHALQYGTGVFGGIRGYYNEAKQNLYVFRLPEHCKRLVNSTKIMQLQIKITPEE
IQTIILDLLRKNEAKQNVYLRPFIYTSALQLSPRFHDVKADITVYALKLDDYLDTQNGLTTMVSSWQRFSDNQIPTLSKV
SGGYVNSALAKSEAVQNGMDEAIFLDARGFVSEGSAENLFIVRDGVIHTPTIPSSILEGITRRSIIQIAKDLGYQVIERD
IARSELYIADELFFSGTGVQVAWVKEVDRRVIGNGTIGPVTKKIQSIFFETVRGEDPKYMNWLTPVY
>Mature_306_residues
AQNSFPYTYFEGKIVPSEDAKVSVQTHALQYGTGVFGGIRGYYNEAKQNLYVFRLPEHCKRLVNSTKIMQLQIKITPEEI
QTIILDLLRKNEAKQNVYLRPFIYTSALQLSPRFHDVKADITVYALKLDDYLDTQNGLTTMVSSWQRFSDNQIPTLSKVS
GGYVNSALAKSEAVQNGMDEAIFLDARGFVSEGSAENLFIVRDGVIHTPTIPSSILEGITRRSIIQIAKDLGYQVIERDI
ARSELYIADELFFSGTGVQVAWVKEVDRRVIGNGTIGPVTKKIQSIFFETVRGEDPKYMNWLTPVY

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=311, Percent_Identity=41.4790996784566, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34641; Mature: 34510

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQNSFPYTYFEGKIVPSEDAKVSVQTHALQYGTGVFGGIRGYYNEAKQNLYVFRLPEHC
CCCCCCCEEEECCEEECCCCCEEEEEEHEEECCCCHHHHHHHHHHHHHCCEEEEECCHHH
KRLVNSTKIMQLQIKITPEEIQTIILDLLRKNEAKQNVYLRPFIYTSALQLSPRFHDVKA
HHHHCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHHCCCCHHEEEC
DITVYALKLDDYLDTQNGLTTMVSSWQRFSDNQIPTLSKVSGGYVNSALAKSEAVQNGMD
CEEEEEEEECCHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCC
EAIFLDARGFVSEGSAENLFIVRDGVIHTPTIPSSILEGITRRSIIQIAKDLGYQVIERD
CEEEEECCCCCCCCCCCCEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IARSELYIADELFFSGTGVQVAWVKEVDRRVIGNGTIGPVTKKIQSIFFETVRGEDPKYM
HHHHHEEEEHHHEECCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHH
NWLTPVY
CCCCCCC
>Mature Secondary Structure 
AQNSFPYTYFEGKIVPSEDAKVSVQTHALQYGTGVFGGIRGYYNEAKQNLYVFRLPEHC
CCCCCCEEEECCEEECCCCCEEEEEEHEEECCCCHHHHHHHHHHHHHCCEEEEECCHHH
KRLVNSTKIMQLQIKITPEEIQTIILDLLRKNEAKQNVYLRPFIYTSALQLSPRFHDVKA
HHHHCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHHCCCCHHEEEC
DITVYALKLDDYLDTQNGLTTMVSSWQRFSDNQIPTLSKVSGGYVNSALAKSEAVQNGMD
CEEEEEEEECCHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCC
EAIFLDARGFVSEGSAENLFIVRDGVIHTPTIPSSILEGITRRSIIQIAKDLGYQVIERD
CEEEEECCCCCCCCCCCCEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
IARSELYIADELFFSGTGVQVAWVKEVDRRVIGNGTIGPVTKKIQSIFFETVRGEDPKYM
HHHHHEEEEHHHEECCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHH
NWLTPVY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]