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The map label for this gene is yihQ [H]

Identifier: 183222551

GI number: 183222551

Start: 3322602

End: 3324836

Strand: Direct

Name: yihQ [H]

Synonym: LEPBI_I3206

Alternate gene names: 183222551

Gene position: 3322602-3324836 (Clockwise)

Preceding gene: 183222550

Following gene: 183222552

Centisome position: 92.3

GC content: 41.66

Gene sequence:

>2235_bases
ATGGTTTTTCGTTTTTTATCCCTTTGTTCACTATTTTTTTTCTTAGAATGTGCTTCGCATGTTCTCACTCCGATTCCCAT
CACGGAAGAAACCTACCAAGTCTCCAAACAAATCCAATGGATCCAAACACCAAACAAACTCATTCTCAAAAACACATCCT
TTGACCGAAACTTCATTGAACTTTCATTAAACGAACCATTCCTCACAGTCTCAGAAGTAAATACAATTTCCAAATACAGA
ATGGCTTCCTTTAAGTTCGAAGAATCGACCAAACGGACTTGTTCCGAACAAACAGTAGATTCCATCAAAAAAGAAACGGG
CAAAATCACAATCCAAGGGAAACTTTCCGGAAAAAATTGTGTGACCAATTACCAAGTATTGTTTCTCACAAAATCAGATA
CGGAACTTGAATTTAAAATTACTGTCTCAGATGAAACACTGAATCGCATCCATCTCGTTTATGCATCTCATCCGGAAGAA
AAAATTTTTGGCCTCGGGGAACAATTCACTTACGATGAATTCAAAGGGAAAAAACCATTTTTTTTCACAGAAGAACAAGG
GATCGGTCGGGGTGACCAACCCATCACAGCAGGCGCCAATTTACTTGCAGGCGCTGGTGGAAACGCGTATACAACGTATG
CTCCTATCCCCCACTACATCAGTTCTGAAAATCGATCCGTATTTTTTGAAAACAGTGGTTATGCGAAGTTTGATTTCAGT
GATGCACGAAAAACAAAAGTAGAATTTTGGGATTTCCAATCAGAAAAATCGGTCACAGGTACCATTTGGTTAGCAAGTTC
AGCCAAATCTCTGATTGAAACTTATACAAAAAAAACAGGTCGTTTTCCAAAATTACCTGACTGGGCTTATGGAACTTGGC
TAGGAATCCAAGGGGGAACTGAAAAAGTAACAACCATCGTCAAACAAGCGAAAGCTGCCGGTAACCCAGTCACCGCTCTT
TGGATCCAAGATTGGTGTGGTAGACGTGTCACAAATTTCGGGGACCAACTCAAATGGCGTTGGTATGCAGACGAAACCCT
TTACCCGGATTTTAAAAAATTCGTGAAATCAATGAATGATGAGAATGTACAGGTGTTAGGTTATATCAATTCCTTTTTAG
CCGATACCGATCCTAAAAAACCAGGTGATGATTTTACAAACCCACTCCTCACAGAAGCAAAATCCAAAGGATACCTTGTC
AAAAATGAAAAGGGAGAAGATTATCTCATCCAAACTGTCGGTTTTCCTGCTTACCTCATCGACCTCACAAACCCTGCCGC
AGTCAAATGGACAAAGGATCTCATCAAAAAGAATTTAATCGGAATGGGTTTATCCGGTTGGATGGCTGACTTTGGAGAAT
GGTTGCCCTATGATGCCAAACTCCATTCCGGAGTGGATGCAAAGATTTACCACAATCGTTACCCAGTCGACTGGGCACGG
ATCAACCGGGAAGCCATCAAAGAGTCAGGAATGGAAGGAAAAATTGTTTTTTTCACAAGAGCGGGATACAGTTATTCCAA
TGCTCATTCCACATTGTTTTGGGAAGGAGACCAAATGGTCAGTTTTGGAACGAATGATGGACTACCTTCCTCTATCGTTG
GACTCACAACATCGGGTATCAGTGGTTATGCGTTAAATCATAGCGACATTGGTGGATACACTACCATTTCCAATCCCTTA
AAAAACTACCATAGAACAAAGGAAGTATTACTCCGTTGGGCAGAAGTCTCTGCCTTCACACCAGTGTTTCGAACACACGA
GGGAAATCGTCCTCTTAAAAACTGGCAAGTGTATACCTACACAAAACCTGATGGTACAAAATCTCTTGGTGACGAAGATA
CCGTGCAACTCTTTGCCAAAATCGCAAGGATCCATTTTGCCTTAAAACCATATATCCAAAGTTTGGTGGAGGAAGCTTCT
AAAACAGGACTCCCCGTTGTAAGGCACAATGCCATAGTGGAACCAGAAGACAAAATTTTACTCCAATACAAATACCAATT
CTTTCTCGGAGATGACCTACTCGTCGCACCCGTTGTAGAATCCAACGAAATTGTTCAGGAAGTGTATCTCCCACGTGGGA
AGTGGTCTCATATTTGGACAGGAACCAATTTCGAAGGGAATCGGAAAATCCAAGTTTCCGCTCCCATAGGCAAACCACCA
GCCTTCATCCGAGTGGGTGGAAAGTCTGAAATGTTGATTCGGTCATCTCTCGAAAGCATTCGGAACAAACAGTAA

Upstream 100 bases:

>100_bases
AGCTCCAAGAGTCGGCGGGGTCGATCGCAAGAAAGTCTAAAAAAAGATTTACGAATCCTTTGACCATCGGTTCACTAAGC
TCTCGCTCTTGGAGGATCCG

Downstream 100 bases:

>100_bases
GGAAACACCAAATGAAATTTGCATTGATAGGTGATATCCATGGGTATTGGAACAAAGAGGACATCGAATATTTTAACGAG
TCCGATTACGATTTTTTATT

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MVFRFLSLCSLFFFLECASHVLTPIPITEETYQVSKQIQWIQTPNKLILKNTSFDRNFIELSLNEPFLTVSEVNTISKYR
MASFKFEESTKRTCSEQTVDSIKKETGKITIQGKLSGKNCVTNYQVLFLTKSDTELEFKITVSDETLNRIHLVYASHPEE
KIFGLGEQFTYDEFKGKKPFFFTEEQGIGRGDQPITAGANLLAGAGGNAYTTYAPIPHYISSENRSVFFENSGYAKFDFS
DARKTKVEFWDFQSEKSVTGTIWLASSAKSLIETYTKKTGRFPKLPDWAYGTWLGIQGGTEKVTTIVKQAKAAGNPVTAL
WIQDWCGRRVTNFGDQLKWRWYADETLYPDFKKFVKSMNDENVQVLGYINSFLADTDPKKPGDDFTNPLLTEAKSKGYLV
KNEKGEDYLIQTVGFPAYLIDLTNPAAVKWTKDLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWAR
INREAIKESGMEGKIVFFTRAGYSYSNAHSTLFWEGDQMVSFGTNDGLPSSIVGLTTSGISGYALNHSDIGGYTTISNPL
KNYHRTKEVLLRWAEVSAFTPVFRTHEGNRPLKNWQVYTYTKPDGTKSLGDEDTVQLFAKIARIHFALKPYIQSLVEEAS
KTGLPVVRHNAIVEPEDKILLQYKYQFFLGDDLLVAPVVESNEIVQEVYLPRGKWSHIWTGTNFEGNRKIQVSAPIGKPP
AFIRVGGKSEMLIRSSLESIRNKQ

Sequences:

>Translated_744_residues
MVFRFLSLCSLFFFLECASHVLTPIPITEETYQVSKQIQWIQTPNKLILKNTSFDRNFIELSLNEPFLTVSEVNTISKYR
MASFKFEESTKRTCSEQTVDSIKKETGKITIQGKLSGKNCVTNYQVLFLTKSDTELEFKITVSDETLNRIHLVYASHPEE
KIFGLGEQFTYDEFKGKKPFFFTEEQGIGRGDQPITAGANLLAGAGGNAYTTYAPIPHYISSENRSVFFENSGYAKFDFS
DARKTKVEFWDFQSEKSVTGTIWLASSAKSLIETYTKKTGRFPKLPDWAYGTWLGIQGGTEKVTTIVKQAKAAGNPVTAL
WIQDWCGRRVTNFGDQLKWRWYADETLYPDFKKFVKSMNDENVQVLGYINSFLADTDPKKPGDDFTNPLLTEAKSKGYLV
KNEKGEDYLIQTVGFPAYLIDLTNPAAVKWTKDLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWAR
INREAIKESGMEGKIVFFTRAGYSYSNAHSTLFWEGDQMVSFGTNDGLPSSIVGLTTSGISGYALNHSDIGGYTTISNPL
KNYHRTKEVLLRWAEVSAFTPVFRTHEGNRPLKNWQVYTYTKPDGTKSLGDEDTVQLFAKIARIHFALKPYIQSLVEEAS
KTGLPVVRHNAIVEPEDKILLQYKYQFFLGDDLLVAPVVESNEIVQEVYLPRGKWSHIWTGTNFEGNRKIQVSAPIGKPP
AFIRVGGKSEMLIRSSLESIRNKQ
>Mature_744_residues
MVFRFLSLCSLFFFLECASHVLTPIPITEETYQVSKQIQWIQTPNKLILKNTSFDRNFIELSLNEPFLTVSEVNTISKYR
MASFKFEESTKRTCSEQTVDSIKKETGKITIQGKLSGKNCVTNYQVLFLTKSDTELEFKITVSDETLNRIHLVYASHPEE
KIFGLGEQFTYDEFKGKKPFFFTEEQGIGRGDQPITAGANLLAGAGGNAYTTYAPIPHYISSENRSVFFENSGYAKFDFS
DARKTKVEFWDFQSEKSVTGTIWLASSAKSLIETYTKKTGRFPKLPDWAYGTWLGIQGGTEKVTTIVKQAKAAGNPVTAL
WIQDWCGRRVTNFGDQLKWRWYADETLYPDFKKFVKSMNDENVQVLGYINSFLADTDPKKPGDDFTNPLLTEAKSKGYLV
KNEKGEDYLIQTVGFPAYLIDLTNPAAVKWTKDLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWAR
INREAIKESGMEGKIVFFTRAGYSYSNAHSTLFWEGDQMVSFGTNDGLPSSIVGLTTSGISGYALNHSDIGGYTTISNPL
KNYHRTKEVLLRWAEVSAFTPVFRTHEGNRPLKNWQVYTYTKPDGTKSLGDEDTVQLFAKIARIHFALKPYIQSLVEEAS
KTGLPVVRHNAIVEPEDKILLQYKYQFFLGDDLLVAPVVESNEIVQEVYLPRGKWSHIWTGTNFEGNRKIQVSAPIGKPP
AFIRVGGKSEMLIRSSLESIRNKQ

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=447, Percent_Identity=23.2662192393736, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI66346737, Length=353, Percent_Identity=26.3456090651558, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI88900491, Length=380, Percent_Identity=25, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI38202257, Length=380, Percent_Identity=25, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310115361, Length=260, Percent_Identity=25.7692307692308, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI221316699, Length=260, Percent_Identity=25.7692307692308, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367323, Length=666, Percent_Identity=39.9399399399399, Blast_Score=460, Evalue=1e-130,
Organism=Escherichia coli, GI2367256, Length=576, Percent_Identity=22.5694444444444, Blast_Score=149, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17560798, Length=273, Percent_Identity=26.007326007326, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560800, Length=273, Percent_Identity=26.007326007326, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71991189, Length=321, Percent_Identity=25.5451713395639, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319706, Length=548, Percent_Identity=22.4452554744526, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650054, Length=389, Percent_Identity=23.3933161953728, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 84245; Mature: 84245

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFRFLSLCSLFFFLECASHVLTPIPITEETYQVSKQIQWIQTPNKLILKNTSFDRNFIE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEECCCEEEEECCCCCCCEEE
LSLNEPFLTVSEVNTISKYRMASFKFEESTKRTCSEQTVDSIKKETGKITIQGKLSGKNC
EECCCCEEEHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
VTNYQVLFLTKSDTELEFKITVSDETLNRIHLVYASHPEEKIFGLGEQFTYDEFKGKKPF
EEEEEEEEEEECCCEEEEEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCHHHHCCCCCE
FFTEEQGIGRGDQPITAGANLLAGAGGNAYTTYAPIPHYISSENRSVFFENSGYAKFDFS
EEECCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCCHHHCCCCCEEEEECCCEEEEECC
DARKTKVEFWDFQSEKSVTGTIWLASSAKSLIETYTKKTGRFPKLPDWAYGTWLGIQGGT
CCCCCEEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCH
EKVTTIVKQAKAAGNPVTALWIQDWCGRRVTNFGDQLKWRWYADETLYPDFKKFVKSMND
HHHHHHHHHHHHCCCCEEEEEEHHHCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCC
ENVQVLGYINSFLADTDPKKPGDDFTNPLLTEAKSKGYLVKNEKGEDYLIQTVGFPAYLI
CCEEEEEEHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCEEEEECCCCEEEE
DLTNPAAVKWTKDLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWAR
ECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCCHHHH
INREAIKESGMEGKIVFFTRAGYSYSNAHSTLFWEGDQMVSFGTNDGLPSSIVGLTTSGI
HCHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHEEEECCC
SGYALNHSDIGGYTTISNPLKNYHRTKEVLLRWAEVSAFTPVFRTHEGNRPLKNWQVYTY
CCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEE
TKPDGTKSLGDEDTVQLFAKIARIHFALKPYIQSLVEEASKTGLPVVRHNAIVEPEDKIL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEECCCCCEE
LQYKYQFFLGDDLLVAPVVESNEIVQEVYLPRGKWSHIWTGTNFEGNRKIQVSAPIGKPP
EEEEEEEEECCCEEEEEECCCHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEECCCCCCC
AFIRVGGKSEMLIRSSLESIRNKQ
CEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFRFLSLCSLFFFLECASHVLTPIPITEETYQVSKQIQWIQTPNKLILKNTSFDRNFIE
CHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEECCCEEEEECCCCCCCEEE
LSLNEPFLTVSEVNTISKYRMASFKFEESTKRTCSEQTVDSIKKETGKITIQGKLSGKNC
EECCCCEEEHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
VTNYQVLFLTKSDTELEFKITVSDETLNRIHLVYASHPEEKIFGLGEQFTYDEFKGKKPF
EEEEEEEEEEECCCEEEEEEEECCCCCCEEEEEEECCCHHHHHCCCCCCCHHHHCCCCCE
FFTEEQGIGRGDQPITAGANLLAGAGGNAYTTYAPIPHYISSENRSVFFENSGYAKFDFS
EEECCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCCHHHCCCCCEEEEECCCEEEEECC
DARKTKVEFWDFQSEKSVTGTIWLASSAKSLIETYTKKTGRFPKLPDWAYGTWLGIQGGT
CCCCCEEEEEECCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCH
EKVTTIVKQAKAAGNPVTALWIQDWCGRRVTNFGDQLKWRWYADETLYPDFKKFVKSMND
HHHHHHHHHHHHCCCCEEEEEEHHHCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCC
ENVQVLGYINSFLADTDPKKPGDDFTNPLLTEAKSKGYLVKNEKGEDYLIQTVGFPAYLI
CCEEEEEEHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCEEEEECCCCEEEE
DLTNPAAVKWTKDLIKKNLIGMGLSGWMADFGEWLPYDAKLHSGVDAKIYHNRYPVDWAR
ECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHCCCCCEEEECCCCCCHHHH
INREAIKESGMEGKIVFFTRAGYSYSNAHSTLFWEGDQMVSFGTNDGLPSSIVGLTTSGI
HCHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHEEEECCC
SGYALNHSDIGGYTTISNPLKNYHRTKEVLLRWAEVSAFTPVFRTHEGNRPLKNWQVYTY
CCEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEEE
TKPDGTKSLGDEDTVQLFAKIARIHFALKPYIQSLVEEASKTGLPVVRHNAIVEPEDKIL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEECCCCCEE
LQYKYQFFLGDDLLVAPVVESNEIVQEVYLPRGKWSHIWTGTNFEGNRKIQVSAPIGKPP
EEEEEEEEECCCEEEEEECCCHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEECCCCCCC
AFIRVGGKSEMLIRSSLESIRNKQ
CEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]