Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 183222389

GI number: 183222389

Start: 3156727

End: 3157902

Strand: Reverse

Name: crp [C]

Synonym: LEPBI_I3043

Alternate gene names: 183222389

Gene position: 3157902-3156727 (Counterclockwise)

Preceding gene: 183222394

Following gene: 183222383

Centisome position: 87.73

GC content: 42.6

Gene sequence:

>1176_bases
ATGAGTCATATCAAAGTCCATTTGGCAACGACGGAAGAAGATCGTAATAAAATTTACCACCTCCGTTACGATATCTATGT
TCAAGAAATGAACAGAGTCCAAGAATATGCGGACCATTCGACAAAAATGATTAAGGAACCGTTTGATGAAACGGGCCATC
TTTTTCTTGCGGAAACCGAAGAAGGGGAGATCATCGGGACCGTTCGCATCAACTTTCGTAAAGATGGGAGTTTGGAATGT
GAAGAGCTTTATGAAATGGAACTCTTCCGCCCCTTCTATCCTGACAAGGTCTCCATGTCGACCAAACTGATGGTGAAACG
TGAATACCGTCATACTGCTGCAGCCAGTATGCTTTGTATGAAGATCTACGAACATGCAAGGGAAAACGGGATCGTCATCG
ATTTTATAGATACCAATCCACACTTGGTGCGTTTGTACAACCAAGTTGGGTACAGAATGTACAAAAAGAACATCCACCAT
CCGGAATACGGCATTGTGATCCCGATGGTATTTTTGTTAGATGATAATGAATACCTAAAACAGATCCATTCACCTTTTCT
ACGTTTGGCGAAGAGATTCACTGCAGGTACTGAGCTTTCTCATCTCTTTGAAACCAAATTTCCTGACTATAAAGACATAA
GGCCTCTCTTCTCCATGGAAGGGGATGATGTTTGGCAAAATATCGTTCATGATATGATGCTCCCTCCGAGCCAGTTTCTC
TCGTTTTTACGAGGGTTTACGGAAGAAGAATCCAAAAAACTTTTATCCATGCTTGATTTAATTGATTATGAAGATGGTGA
CATCGTCTTCCACCAAAACCAAGAAAGCCAAGGATTGTTTTGTGTTTTAGATGGGAGTGTGGAAGTGGTTGTGAACCGCG
AGGATGGTGTGCGTTCGACGATCTCCATTTTAAACCAAGGGGAGATCTTTGGGGAACTGGGCTTTGTGGCAAAATCAAAT
CGTAATGCAGACATCATCGTGCGAGACCATGCGAAACTTCTCATCCTCACACCAAATGAATTTCAAAAATTAGAAATCCA
AAGTCCCACTTTGGCCATCAAACTTTTGACCAATTTGTTTGTCATCCTTGCGCAGAGATTCAATGAAATGTCACGCCGCA
TGCTCGAATTTAGAAGGTTGTACGAGATGGGCGGAGCTTCGAGAAGAGGGGAGTGA

Upstream 100 bases:

>100_bases
TTATATTTCGTTTTAGTAAATGCGGAAAATTAACTGATAACGTCATACATTTTGCATAAATTGCAAATGATTTTTCAAAT
TTTTAAGGAGGACGGCAAGT

Downstream 100 bases:

>100_bases
GGAAAGTGGTTTAGGAAATTTCCAAAACCACTTGGTCCCAAAGTTTTTTAAAATTGGAAAGGGATTTTGACTGCCAAGAA
ACGTTGAGGGAACCTTTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: None

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSHIKVHLATTEEDRNKIYHLRYDIYVQEMNRVQEYADHSTKMIKEPFDETGHLFLAETEEGEIIGTVRINFRKDGSLEC
EELYEMELFRPFYPDKVSMSTKLMVKREYRHTAAASMLCMKIYEHARENGIVIDFIDTNPHLVRLYNQVGYRMYKKNIHH
PEYGIVIPMVFLLDDNEYLKQIHSPFLRLAKRFTAGTELSHLFETKFPDYKDIRPLFSMEGDDVWQNIVHDMMLPPSQFL
SFLRGFTEEESKKLLSMLDLIDYEDGDIVFHQNQESQGLFCVLDGSVEVVVNREDGVRSTISILNQGEIFGELGFVAKSN
RNADIIVRDHAKLLILTPNEFQKLEIQSPTLAIKLLTNLFVILAQRFNEMSRRMLEFRRLYEMGGASRRGE

Sequences:

>Translated_391_residues
MSHIKVHLATTEEDRNKIYHLRYDIYVQEMNRVQEYADHSTKMIKEPFDETGHLFLAETEEGEIIGTVRINFRKDGSLEC
EELYEMELFRPFYPDKVSMSTKLMVKREYRHTAAASMLCMKIYEHARENGIVIDFIDTNPHLVRLYNQVGYRMYKKNIHH
PEYGIVIPMVFLLDDNEYLKQIHSPFLRLAKRFTAGTELSHLFETKFPDYKDIRPLFSMEGDDVWQNIVHDMMLPPSQFL
SFLRGFTEEESKKLLSMLDLIDYEDGDIVFHQNQESQGLFCVLDGSVEVVVNREDGVRSTISILNQGEIFGELGFVAKSN
RNADIIVRDHAKLLILTPNEFQKLEIQSPTLAIKLLTNLFVILAQRFNEMSRRMLEFRRLYEMGGASRRGE
>Mature_390_residues
SHIKVHLATTEEDRNKIYHLRYDIYVQEMNRVQEYADHSTKMIKEPFDETGHLFLAETEEGEIIGTVRINFRKDGSLECE
ELYEMELFRPFYPDKVSMSTKLMVKREYRHTAAASMLCMKIYEHARENGIVIDFIDTNPHLVRLYNQVGYRMYKKNIHHP
EYGIVIPMVFLLDDNEYLKQIHSPFLRLAKRFTAGTELSHLFETKFPDYKDIRPLFSMEGDDVWQNIVHDMMLPPSQFLS
FLRGFTEEESKKLLSMLDLIDYEDGDIVFHQNQESQGLFCVLDGSVEVVVNREDGVRSTISILNQGEIFGELGFVAKSNR
NADIIVRDHAKLLILTPNEFQKLEIQSPTLAIKLLTNLFVILAQRFNEMSRRMLEFRRLYEMGGASRRGE

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45814; Mature: 45683

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHIKVHLATTEEDRNKIYHLRYDIYVQEMNRVQEYADHSTKMIKEPFDETGHLFLAETE
CCEEEEEEEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
EGEIIGTVRINFRKDGSLECEELYEMELFRPFYPDKVSMSTKLMVKREYRHTAAASMLCM
CCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KIYEHARENGIVIDFIDTNPHLVRLYNQVGYRMYKKNIHHPEYGIVIPMVFLLDDNEYLK
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCHHHHH
QIHSPFLRLAKRFTAGTELSHLFETKFPDYKDIRPLFSMEGDDVWQNIVHDMMLPPSQFL
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCHHHCCCCHHHHHHHHHHHCCCHHHHH
SFLRGFTEEESKKLLSMLDLIDYEDGDIVFHQNQESQGLFCVLDGSVEVVVNREDGVRST
HHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCEEEEEECCCCHHHH
ISILNQGEIFGELGFVAKSNRNADIIVRDHAKLLILTPNEFQKLEIQSPTLAIKLLTNLF
HHHHHCCCHHHHHCCEEECCCCCEEEEECCCEEEEECCCCCEEEEECCCHHHHHHHHHHH
VILAQRFNEMSRRMLEFRRLYEMGGASRRGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SHIKVHLATTEEDRNKIYHLRYDIYVQEMNRVQEYADHSTKMIKEPFDETGHLFLAETE
CEEEEEEEECCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
EGEIIGTVRINFRKDGSLECEELYEMELFRPFYPDKVSMSTKLMVKREYRHTAAASMLCM
CCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KIYEHARENGIVIDFIDTNPHLVRLYNQVGYRMYKKNIHHPEYGIVIPMVFLLDDNEYLK
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCHHHHH
QIHSPFLRLAKRFTAGTELSHLFETKFPDYKDIRPLFSMEGDDVWQNIVHDMMLPPSQFL
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHCCHHHCCCCHHHHHHHHHHHCCCHHHHH
SFLRGFTEEESKKLLSMLDLIDYEDGDIVFHQNQESQGLFCVLDGSVEVVVNREDGVRST
HHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEECCCEEEEEECCCCHHHH
ISILNQGEIFGELGFVAKSNRNADIIVRDHAKLLILTPNEFQKLEIQSPTLAIKLLTNLF
HHHHHCCCHHHHHCCEEECCCCCEEEEECCCEEEEECCCCCEEEEECCCHHHHHHHHHHH
VILAQRFNEMSRRMLEFRRLYEMGGASRRGE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA