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The map label for this gene is ahpF [H]

Identifier: 183222355

GI number: 183222355

Start: 3121529

End: 3123088

Strand: Reverse

Name: ahpF [H]

Synonym: LEPBI_I3008

Alternate gene names: 183222355

Gene position: 3123088-3121529 (Counterclockwise)

Preceding gene: 183222356

Following gene: 183222352

Centisome position: 86.76

GC content: 39.29

Gene sequence:

>1560_bases
ATGTTAGATGAATCAACCAAACAACAAGTAAAACAATACTTTGAAAGGATTAAAAATCCAGTCAGCATTACATTGTATTC
TGGTGACCATGAAAAAAGGGAAGAGTTAGTTTCCTTTCTCAATGATATCGAATCATTGAGTCCAATGATATCAATCCAAC
ACTCAAGTGATGTCACTGATGGACTACGATTCACGATTATATCAAACGGAAATCCTACTGGAATCCATTTCTCAGGAATT
CCCATGGGACATGAATTTACTTCCTTCATACTAGCGATTTTACAATCCGGAGGTAATCCGATCAAATTGGAAGAAGGGAT
TCTTTCTGCGGTTTCCAAATTGAAAGGTGAGTTTCGGTTTGAAACATTTATTTCCCTTGATTGCCATAATTGCCCTGAGG
TTGTGCAAACTCTAAACAGCTTTGCTTTGGTGAATCCCAACATCTCCCACAACATGATCGACGGAGCGATGTATCCTGAA
TTGGTGAAAGAAAAAAATATCCAAGGTGTTCCTGCTGTATATTTGAACGGAGAACGTTTTTTAAGTGGAAAAGCAGAAGC
ATCGATCATTTTTGATAAACTTTTGGAATTATATACAATTCCCTCTGAGTCAGAATCTAGCGATGGTTTGGCGAATCCTT
CTGAAATTTATGATGTCACTGTCATTGGTGGTGGTCCATCTGGAGTGACTGCAGCCGTTTATGCCGCAAGAAAAGGACTT
AGAACTCTAGTGATTGCCGATCGATTGGGTGGACAAGTAAAAGATACTTTGGGTATCGAAAATATTATCTCAATTCCATA
TACAACTGGGCCTGAATTGATCCATGTCTTGGCTGACCAACTTGAAAAAAACCAAATCAAAAAGAAAGAAAATGTTCGGG
TTCAAAAAATAGAACAAGGACAAACAAAAATCATTCACTTGAACACTGGTGAGAAAATCCTTTCCAAAACTGTGATTTTG
TCTACTGGCGCAAAATGGAGAGAACTCAATGTTCCAGGTGAAAAGGAGTTCGTTGGAAAGGGCGTTGCTTATTGCCCTCA
CTGTGATGGTCCATTTTTTAAAGACAAAGATGTGGCTGTGATCGGTGGAGGAAACTCGGGAGTGGAAGCAGCTTTAGATT
TAAGTGGAATTGTGAAATCTGTCACTTTAGTTGAGTTTGGTGATAAATTAAACGCAGACAAGGTGTTATTGGATAAGGTG
GCAAGTTCTCCAAACATCAAAACTTTGGTCAAAGCGCAAACCACTGAAATTCAAACAGGTGTAGATAAAGTCACAGGGCT
TACCTACAAGGATCGAAATACAGAACAAGTATCAACGATTCCATTGGATGGAGTGTTTGTTCAGATCGGTCTTGTACCAA
ACAGTAGTTTTGTGAAAGACTTAGTGGCAACGAATCGGTTTGGAGAAATTTTGGTCGATGAAAAGTGTAAAACCAATGTG
GATGGAATCTTTGCTTGTGGGGATGTGACAAATACACCTTACAAACAAATTATCATTGCAATGGGAGAAGGGGCAAAGGC
GGCAATCAGCGCTTTTGAATATCTACTACACGCGGCCTAA

Upstream 100 bases:

>100_bases
GGAAACCAGGTAACACAACGTTAAAACCTGGTCTTGACTTGGTAGGAAAAATCTAAACAAAATTAGGCGGGCCTAGCCCG
CCTAAAACTAGGAGGAAGTT

Downstream 100 bases:

>100_bases
CCGAAGCCACTTTTCTACAGTCGCATACAGATGGGATGCGGAAATGGGTTTGGTTAAAAAATCGTCCATTCCCGATTCCA
TCGCAGAATCCTTTACAGCA

Product: alkyl hydroperoxide reductase subunit F

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MLDESTKQQVKQYFERIKNPVSITLYSGDHEKREELVSFLNDIESLSPMISIQHSSDVTDGLRFTIISNGNPTGIHFSGI
PMGHEFTSFILAILQSGGNPIKLEEGILSAVSKLKGEFRFETFISLDCHNCPEVVQTLNSFALVNPNISHNMIDGAMYPE
LVKEKNIQGVPAVYLNGERFLSGKAEASIIFDKLLELYTIPSESESSDGLANPSEIYDVTVIGGGPSGVTAAVYAARKGL
RTLVIADRLGGQVKDTLGIENIISIPYTTGPELIHVLADQLEKNQIKKKENVRVQKIEQGQTKIIHLNTGEKILSKTVIL
STGAKWRELNVPGEKEFVGKGVAYCPHCDGPFFKDKDVAVIGGGNSGVEAALDLSGIVKSVTLVEFGDKLNADKVLLDKV
ASSPNIKTLVKAQTTEIQTGVDKVTGLTYKDRNTEQVSTIPLDGVFVQIGLVPNSSFVKDLVATNRFGEILVDEKCKTNV
DGIFACGDVTNTPYKQIIIAMGEGAKAAISAFEYLLHAA

Sequences:

>Translated_519_residues
MLDESTKQQVKQYFERIKNPVSITLYSGDHEKREELVSFLNDIESLSPMISIQHSSDVTDGLRFTIISNGNPTGIHFSGI
PMGHEFTSFILAILQSGGNPIKLEEGILSAVSKLKGEFRFETFISLDCHNCPEVVQTLNSFALVNPNISHNMIDGAMYPE
LVKEKNIQGVPAVYLNGERFLSGKAEASIIFDKLLELYTIPSESESSDGLANPSEIYDVTVIGGGPSGVTAAVYAARKGL
RTLVIADRLGGQVKDTLGIENIISIPYTTGPELIHVLADQLEKNQIKKKENVRVQKIEQGQTKIIHLNTGEKILSKTVIL
STGAKWRELNVPGEKEFVGKGVAYCPHCDGPFFKDKDVAVIGGGNSGVEAALDLSGIVKSVTLVEFGDKLNADKVLLDKV
ASSPNIKTLVKAQTTEIQTGVDKVTGLTYKDRNTEQVSTIPLDGVFVQIGLVPNSSFVKDLVATNRFGEILVDEKCKTNV
DGIFACGDVTNTPYKQIIIAMGEGAKAAISAFEYLLHAA
>Mature_519_residues
MLDESTKQQVKQYFERIKNPVSITLYSGDHEKREELVSFLNDIESLSPMISIQHSSDVTDGLRFTIISNGNPTGIHFSGI
PMGHEFTSFILAILQSGGNPIKLEEGILSAVSKLKGEFRFETFISLDCHNCPEVVQTLNSFALVNPNISHNMIDGAMYPE
LVKEKNIQGVPAVYLNGERFLSGKAEASIIFDKLLELYTIPSESESSDGLANPSEIYDVTVIGGGPSGVTAAVYAARKGL
RTLVIADRLGGQVKDTLGIENIISIPYTTGPELIHVLADQLEKNQIKKKENVRVQKIEQGQTKIIHLNTGEKILSKTVIL
STGAKWRELNVPGEKEFVGKGVAYCPHCDGPFFKDKDVAVIGGGNSGVEAALDLSGIVKSVTLVEFGDKLNADKVLLDKV
ASSPNIKTLVKAQTTEIQTGVDKVTGLTYKDRNTEQVSTIPLDGVFVQIGLVPNSSFVKDLVATNRFGEILVDEKCKTNV
DGIFACGDVTNTPYKQIIIAMGEGAKAAISAFEYLLHAA

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone [H]

COG id: COG3634

COG function: function code O; Alkyl hydroperoxide reductase, large subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=522, Percent_Identity=44.2528735632184, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=35.6913183279743, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=30.5732484076433, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=29.746835443038, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 56246; Mature: 56246

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDESTKQQVKQYFERIKNPVSITLYSGDHEKREELVSFLNDIESLSPMISIQHSSDVTD
CCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
GLRFTIISNGNPTGIHFSGIPMGHEFTSFILAILQSGGNPIKLEEGILSAVSKLKGEFRF
CEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEE
ETFISLDCHNCPEVVQTLNSFALVNPNISHNMIDGAMYPELVKEKNIQGVPAVYLNGERF
EEEEEECCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCEE
LSGKAEASIIFDKLLELYTIPSESESSDGLANPSEIYDVTVIGGGPSGVTAAVYAARKGL
ECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCC
RTLVIADRLGGQVKDTLGIENIISIPYTTGPELIHVLADQLEKNQIKKKENVRVQKIEQG
EEEEEEHHCCCCHHHHCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
QTKIIHLNTGEKILSKTVILSTGAKWRELNVPGEKEFVGKGVAYCPHCDGPFFKDKDVAV
CEEEEEECCCHHHHHCEEEEECCCCEEEECCCCCHHHHCCCCEECCCCCCCCCCCCCEEE
IGGGNSGVEAALDLSGIVKSVTLVEFGDKLNADKVLLDKVASSPNIKTLVKAQTTEIQTG
EECCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHHC
VDKVTGLTYKDRNTEQVSTIPLDGVFVQIGLVPNSSFVKDLVATNRFGEILVDEKCKTNV
HHHHCCCEECCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHCCCCCCEEECCCCCCCC
DGIFACGDVTNTPYKQIIIAMGEGAKAAISAFEYLLHAA
CCEEEECCCCCCCHHEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDESTKQQVKQYFERIKNPVSITLYSGDHEKREELVSFLNDIESLSPMISIQHSSDVTD
CCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
GLRFTIISNGNPTGIHFSGIPMGHEFTSFILAILQSGGNPIKLEEGILSAVSKLKGEFRF
CEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEE
ETFISLDCHNCPEVVQTLNSFALVNPNISHNMIDGAMYPELVKEKNIQGVPAVYLNGERF
EEEEEECCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCEE
LSGKAEASIIFDKLLELYTIPSESESSDGLANPSEIYDVTVIGGGPSGVTAAVYAARKGL
ECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCC
RTLVIADRLGGQVKDTLGIENIISIPYTTGPELIHVLADQLEKNQIKKKENVRVQKIEQG
EEEEEEHHCCCCHHHHCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
QTKIIHLNTGEKILSKTVILSTGAKWRELNVPGEKEFVGKGVAYCPHCDGPFFKDKDVAV
CEEEEEECCCHHHHHCEEEEECCCCEEEECCCCCHHHHCCCCEECCCCCCCCCCCCCEEE
IGGGNSGVEAALDLSGIVKSVTLVEFGDKLNADKVLLDKVASSPNIKTLVKAQTTEIQTG
EECCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHHC
VDKVTGLTYKDRNTEQVSTIPLDGVFVQIGLVPNSSFVKDLVATNRFGEILVDEKCKTNV
HHHHCCCEECCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHCCCCCCEEECCCCCCCC
DGIFACGDVTNTPYKQIIIAMGEGAKAAISAFEYLLHAA
CCEEEECCCCCCCHHEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1917890; 2760020 [H]