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The map label for this gene is aatA [H]

Identifier: 183221904

GI number: 183221904

Start: 2631001

End: 2632218

Strand: Reverse

Name: aatA [H]

Synonym: LEPBI_I2543

Alternate gene names: 183221904

Gene position: 2632218-2631001 (Counterclockwise)

Preceding gene: 183221905

Following gene: 183221903

Centisome position: 73.12

GC content: 42.94

Gene sequence:

>1218_bases
ATGAAACTTGTAGCAAAACGACTCGATGTCGTAGAACCTTCTCCCACTCTCGCGATCACGGCGAAAGCCAATCAGTTAAA
AGCGAGTGGCCTTGATGTGGTTGGATTTGGAGCAGGGGAACCTGACTTTGATACACCAAATCATATCAAAGAAGCTGCTA
AAAAAGCGATGGACCAAGGGAAAACAAAATACACTCCCGTGAGTGGAACTGTTTCCCTAAAAGATGCCATCATTAAAAAG
TTTGAAACTGAAAATGGTTTAAAATACGAAAAAAACCAAATCATTGTCGGAACAGGTGGGAAACAGGTTCTCTACAATTT
TTTTATGGCGACTCTCAATCCTGGTGATGAAGTGATCATCCCAGCGCCGTATTGGGTAAGTTATGCGGACATCGTTCGAT
TGGCAGAAGGGACACCCGTGATTGTAGCTACTGATATTTCCAGTGGATTTAAAATCACAGCGGAACAATTGGAAAAAGCC
ATCACACCCAAAACCAAAGTGTTTATTTTTAACTCTCCTTCCAATCCAACAGGAGCCGCTTACACTCGTTCCGATGTGGA
AGCACTTGTAAAGGTTTTGGAACCAAAAGACATCATCACTGTCTCCGATGATATCTACGAAAAAATCATCTATGATGGAT
TGGAATTTGTGAATCCTGCGATGATCTCAGCTAAGATGAAGGAAAAAACCTTTGTCATCAATGGAGTGTCCAAAGCCTAT
TCCATGACAGGATGGAGGATTGGATACGGGGCAGGCAATGCCGAGATTGTGAAAAACATGGATACCATGCAAGGCCAATC
CACAAGTAACGCTTCTTCCATTTCCCAAGCGGCGGCTGAAGCGGCTCTAACTGGAGACCAAACACCAGTAGCGGAAATGC
TAAAGGCTTTTGACAAACGTAGAAAACTCATCGTGGGGTTACTCCGTGAGATCCCTGGGGTGGAATGCCGGATGCCAGAA
GGTGCTTTTTATGCATTTCCATATATGACAGGTGTGTATGAAATGCCTGGATTCAAAAAACTTCTCGCTGAAACAAAAGA
AACTTCTTATTCCAAACTTTTTTGTGATGTCCTCCTCGAGAAATACAATGTGGCAGCAGTGCCAGGAATTGCCTTCGGAG
ATGACAAAGCCATTCGTTTGTCGTATGCGTTAGGTGAAAAAGACATTGAAAAAGGTGTCTCTCGCATCAAACAAATGGTA
GAGGATTTACAAAAATAA

Upstream 100 bases:

>100_bases
AACTCTTCCTCACCGAACAAGGGTATGAATACGAAATTTATACTTTGGACCAGTTCAAAGAAACGGTTCCAGAAGAATCA
CTCACGAAATAGAGGACAAA

Downstream 100 bases:

>100_bases
AATGAAACCTGTCCCTTTACTGAAATATCTTGGTAGAGGGGCAAAGTTCACGGAAAAATTGTGGCGATCATATAGATATG
ATTGGAATTCGCAGAAGAGA

Product: aspartate aminotransferase A

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKLVAKRLDVVEPSPTLAITAKANQLKASGLDVVGFGAGEPDFDTPNHIKEAAKKAMDQGKTKYTPVSGTVSLKDAIIKK
FETENGLKYEKNQIIVGTGGKQVLYNFFMATLNPGDEVIIPAPYWVSYADIVRLAEGTPVIVATDISSGFKITAEQLEKA
ITPKTKVFIFNSPSNPTGAAYTRSDVEALVKVLEPKDIITVSDDIYEKIIYDGLEFVNPAMISAKMKEKTFVINGVSKAY
SMTGWRIGYGAGNAEIVKNMDTMQGQSTSNASSISQAAAEAALTGDQTPVAEMLKAFDKRRKLIVGLLREIPGVECRMPE
GAFYAFPYMTGVYEMPGFKKLLAETKETSYSKLFCDVLLEKYNVAAVPGIAFGDDKAIRLSYALGEKDIEKGVSRIKQMV
EDLQK

Sequences:

>Translated_405_residues
MKLVAKRLDVVEPSPTLAITAKANQLKASGLDVVGFGAGEPDFDTPNHIKEAAKKAMDQGKTKYTPVSGTVSLKDAIIKK
FETENGLKYEKNQIIVGTGGKQVLYNFFMATLNPGDEVIIPAPYWVSYADIVRLAEGTPVIVATDISSGFKITAEQLEKA
ITPKTKVFIFNSPSNPTGAAYTRSDVEALVKVLEPKDIITVSDDIYEKIIYDGLEFVNPAMISAKMKEKTFVINGVSKAY
SMTGWRIGYGAGNAEIVKNMDTMQGQSTSNASSISQAAAEAALTGDQTPVAEMLKAFDKRRKLIVGLLREIPGVECRMPE
GAFYAFPYMTGVYEMPGFKKLLAETKETSYSKLFCDVLLEKYNVAAVPGIAFGDDKAIRLSYALGEKDIEKGVSRIKQMV
EDLQK
>Mature_405_residues
MKLVAKRLDVVEPSPTLAITAKANQLKASGLDVVGFGAGEPDFDTPNHIKEAAKKAMDQGKTKYTPVSGTVSLKDAIIKK
FETENGLKYEKNQIIVGTGGKQVLYNFFMATLNPGDEVIIPAPYWVSYADIVRLAEGTPVIVATDISSGFKITAEQLEKA
ITPKTKVFIFNSPSNPTGAAYTRSDVEALVKVLEPKDIITVSDDIYEKIIYDGLEFVNPAMISAKMKEKTFVINGVSKAY
SMTGWRIGYGAGNAEIVKNMDTMQGQSTSNASSISQAAAEAALTGDQTPVAEMLKAFDKRRKLIVGLLREIPGVECRMPE
GAFYAFPYMTGVYEMPGFKKLLAETKETSYSKLFCDVLLEKYNVAAVPGIAFGDDKAIRLSYALGEKDIEKGVSRIKQMV
EDLQK

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=419, Percent_Identity=24.3436754176611, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881279, Length=419, Percent_Identity=24.3436754176611, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713254, Length=310, Percent_Identity=28.0645161290323, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI56713256, Length=315, Percent_Identity=27.9365079365079, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI169881281, Length=416, Percent_Identity=22.1153846153846, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=23.0569948186528, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI4885351, Length=373, Percent_Identity=21.1796246648794, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=24.8704663212435, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788722, Length=406, Percent_Identity=28.3251231527094, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788627, Length=322, Percent_Identity=27.3291925465839, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787710, Length=209, Percent_Identity=23.9234449760766, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=264, Percent_Identity=28.030303030303, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=264, Percent_Identity=28.030303030303, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=348, Percent_Identity=26.1494252873563, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=22.1354166666667, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=24.3107769423559, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6320317, Length=286, Percent_Identity=22.7272727272727, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28573069, Length=340, Percent_Identity=25.8823529411765, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24646114, Length=340, Percent_Identity=25.8823529411765, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573067, Length=340, Percent_Identity=25.8823529411765, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573065, Length=340, Percent_Identity=25.8823529411765, Blast_Score=128, Evalue=8e-30,
Organism=Drosophila melanogaster, GI18859735, Length=323, Percent_Identity=21.9814241486068, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24641770, Length=369, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641760, Length=369, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641768, Length=369, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641766, Length=369, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641764, Length=369, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45551451, Length=369, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44127; Mature: 44127

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVAKRLDVVEPSPTLAITAKANQLKASGLDVVGFGAGEPDFDTPNHIKEAAKKAMDQG
CCCHHHHCCCCCCCCCEEEEECCCHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
KTKYTPVSGTVSLKDAIIKKFETENGLKYEKNQIIVGTGGKQVLYNFFMATLNPGDEVII
CCEECCCCCCCHHHHHHHHHHCCCCCCEEECCEEEEECCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYADIVRLAEGTPVIVATDISSGFKITAEQLEKAITPKTKVFIFNSPSNPTGAA
CCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCC
YTRSDVEALVKVLEPKDIITVSDDIYEKIIYDGLEFVNPAMISAKMKEKTFVINGVSKAY
EEHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEECHHHHH
SMTGWRIGYGAGNAEIVKNMDTMQGQSTSNASSISQAAAEAALTGDQTPVAEMLKAFDKR
HCCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RKLIVGLLREIPGVECRMPEGAFYAFPYMTGVYEMPGFKKLLAETKETSYSKLFCDVLLE
HHHHHHHHHHCCCCEEECCCCCEEECHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
KYNVAAVPGIAFGDDKAIRLSYALGEKDIEKGVSRIKQMVEDLQK
HCCEEECCCEEECCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLVAKRLDVVEPSPTLAITAKANQLKASGLDVVGFGAGEPDFDTPNHIKEAAKKAMDQG
CCCHHHHCCCCCCCCCEEEEECCCHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
KTKYTPVSGTVSLKDAIIKKFETENGLKYEKNQIIVGTGGKQVLYNFFMATLNPGDEVII
CCEECCCCCCCHHHHHHHHHHCCCCCCEEECCEEEEECCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYADIVRLAEGTPVIVATDISSGFKITAEQLEKAITPKTKVFIFNSPSNPTGAA
CCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCC
YTRSDVEALVKVLEPKDIITVSDDIYEKIIYDGLEFVNPAMISAKMKEKTFVINGVSKAY
EEHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEECHHHHH
SMTGWRIGYGAGNAEIVKNMDTMQGQSTSNASSISQAAAEAALTGDQTPVAEMLKAFDKR
HCCCEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RKLIVGLLREIPGVECRMPEGAFYAFPYMTGVYEMPGFKKLLAETKETSYSKLFCDVLLE
HHHHHHHHHHCCCCEEECCCCCEEECHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
KYNVAAVPGIAFGDDKAIRLSYALGEKDIEKGVSRIKQMVEDLQK
HCCEEECCCEEECCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]