| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is greA [H]
Identifier: 183221706
GI number: 183221706
Start: 2404562
End: 2407327
Strand: Reverse
Name: greA [H]
Synonym: LEPBI_I2333
Alternate gene names: 183221706
Gene position: 2407327-2404562 (Counterclockwise)
Preceding gene: 183221707
Following gene: 183221704
Centisome position: 66.88
GC content: 39.15
Gene sequence:
>2766_bases ATGCCTGAGACTATTACCGAAGACAAATCAAACAAAATTGCCGACAACGACAAACTCACACCTCTATTTAATGAGGAAAT TTATGTTCGTGCTGATGCAGGAACGGTTCCCGTTTCTAAATTCAAAATCTTTGACGATGTCATTGATGCATACAAGGCAG AAAATCGTCTAGCGGAAGCTAAACAAAAAATTGAAGACCATTTCAAAGAACACCCTGAGTCAATCTCCGCCAAATACATG TTAATGATCATATCTTTCATGGAAGATTCCATGGGAGATGCGAATTTGGTGAAGAACATTTTGGATTCTTTCAAAGCTCA TGCGAAATGGACGATCATTGAATACATAACTGATTCTATTTTACGTTTTGGTGACCATAGACTTGCGCTTCGTGTGAAAG CGGAAGCTCTCGATAAACTCAAGAAAAACAAAGAACTCAAAGTTGTACTTGAAAAATTAGCCAAACAAGACCGCAAAAAC CCAGAGATCGCAAAGAAGTACGGATTCTCCATTATGGAAGAAGACAAACCGAAAGCGATGTCTTATCTCAAACTTGCCGT TGAGATGTATGCAAAAAATAAAGAATACGTTCCGATGGAAGAGATTTGGCCTACCATCGTTCAAAACAATTATGAAGATG TTTCCTTCTTCGATAAAATTGAACGGATCTTACTTGGACAAAGAGAAAAAACTCGGTTAGTCGGTCTATTATACCCAATT GTAGAACCATTCAAAGCAATGGAAGATTGGGATCATGTCATCTATTTTCTAAAGAAAATATTAGAACACGAGCCTGCTTC ACAAAAAGCAAGAAACGAACTCATCCGTTCTTACAAACAAAAATATGTAGCCCATTCACTTTTGGAAGATTTCCTCAAGA TGAGTGAACTTGGTAACAACCGTAAACCGGTCAAACTTTGTATCACAAACTTTGAACGAAACATCGTGTTTGATACTGGT AACTATGTGATGCATAGAAACTGGGGTGTGGGTAAAATCACATCCATCTCTCAAACGGGAGATTCTATCTTTGTTGATTT TGAAGAAAAGAAAGACCACAAACTTTCCATCCAAATGGCAATCACTTCCTTGAAGCCTCTCAAGAAAGACCATATTTGGG TGCAACACTTTGAAGACAGACAAGGTATCAATACTATGTTTGCTGAGAACTTACCTGAGTTCTTAAAACAACTTCTGAAA TCTTACGACAACCGAATGATCATCGGTGACATGAAGAACGAACTCATTGGAACCTTCCTGAAACAAGAGGAATGGTCTAA GTGGTGGGCAAAGGTAAAATCGGTTCTGAAAAAAGAAGCGAACATTGGAATGAATCCGAAGAAAAAGGATGAAGTGGTAT ACCACGAAAAACCAATCACTCACTCTGAAACCCTCACTCAAAAATTCCAAGCTAGTAATGATGCGAATAAAAAATTAGAA ATCGCAATGGAAGCAGTGCGCGATTCTGATGAAGCTGCGGAAGCGGGTGAGTTTTTTATCTCTCATTATGTGGAAGAAGA ATCGGCTCGTGACATCATTCGTAAAATTTCTGCTTATCTATACTTGGAAGAAGCAGGAAAGGCGTGGCCAACAGAAGAAT TTTCGCATAAAATCAGAGAACCTGAATTAAAAACCCTAATCCAAACTCTAACAAAAGAGGATGCTCTCAAAATTTCAAAG GCATTGGAAAACACGGATATCAAAAAAGGTTTCAAAGACCTGATTCGATCGCACCACCCAGAAGCGATCAATATCCTCAT CGGACTTCTTTTTGAAGTGCCAGTGAAGGTAAACAGGTCTGTTTTCCAAAACTTGGTTGCTGATGAAAAGTATGCAGAAC TCAATTTGTTTTTCGAAACGGTTTGTAACAAATCCAAAGAAAACCCTGAAGTTTTCCTTTGGGTGGCAAAATCCATTCTT TCTCATACCTGGAAATTTGATTGGCTAAAAGTCAGTGAAGAAGACCTCGTACTGCGAGTGTTCCGAATCTTAAAACCACT TGCCAAAATTGAAGACAAAGGAACTAAACTCAAAAACCAAGCGATGGACATTTTGTTCGGAAAAGACAATAGTCTTCTCC GCGACATTTTAACCAATGCGGATGATGAGTATGTTCGGAAACTATTTGCTCTTTTCAAAGAAGTCCCTTATGTGACAGAC TTAGAAAAAGACCAATTGTATGCTCTTATCAACGAACTGAAACCAAATATTGTTTGGGACGAGTATGACTCTGAAGAAGA TGCAGACGATGATCCATTGGCAAATCTTCCACACGATGTGGTGCTTGTCACAAGACGCGCGTTTAATGCTAAAAAACTTG AATTTGAACATTTAGTGAATGTGGAAATGGCGGAAAACTCTCGTGATATCGGTGAGGCCCAAGAAAAAGGGGACTTACGT GAAAACGCAGAATACAAAGCGGCGATGGAAAAACAAGCACAGCTCCAAGCGGCCATCAAACGTTTAGAAGCTGAACTCAA AAGTGCTCGAATTTTAGATTTAAGTGATGTCAAAACAGAAAAAGTAGGGATCGGAACCACTGTGCGTTTGAAAAACAAAC AAACTGGTGAGTCTGTCACTTACTCGATCTTAGGTGCATGGGATGCTGATACTGAAAAAAATATCATCTCTTACCAATCA CCGCTCGCAAAATCCTTACTTGGAAAACACACAGGAAACGAAGCAACACTTGTCTTTGGTTCTACAGAAACAGTTTACGA AGTTTTGGATATTGCCCGTTACTCAATGACTGGACAGGAAGCCTGA
Upstream 100 bases:
>100_bases GGACTGTTCTTTTCGCGGATTCATCGCTAAATTTACCGTAACAACTTTATAGGAACTATGAACACCCTTTATTGGAAATA CGAAGAGGGAGATTCTTTTC
Downstream 100 bases:
>100_bases AGAAGGTCTTCCTTCCAACCATTTGTAGAAATTAGATCCACAAACGGTTCGGAACTATTTCCGGCAAAATCAGAGGCCTT AACTTCCAAAAGAAGATAAG
Product: fused transcript cleavage factor/unknown domain fusion protein
Products: NA
Alternate protein names: Transcript cleavage factor greA [H]
Number of amino acids: Translated: 921; Mature: 920
Protein sequence:
>921_residues MPETITEDKSNKIADNDKLTPLFNEEIYVRADAGTVPVSKFKIFDDVIDAYKAENRLAEAKQKIEDHFKEHPESISAKYM LMIISFMEDSMGDANLVKNILDSFKAHAKWTIIEYITDSILRFGDHRLALRVKAEALDKLKKNKELKVVLEKLAKQDRKN PEIAKKYGFSIMEEDKPKAMSYLKLAVEMYAKNKEYVPMEEIWPTIVQNNYEDVSFFDKIERILLGQREKTRLVGLLYPI VEPFKAMEDWDHVIYFLKKILEHEPASQKARNELIRSYKQKYVAHSLLEDFLKMSELGNNRKPVKLCITNFERNIVFDTG NYVMHRNWGVGKITSISQTGDSIFVDFEEKKDHKLSIQMAITSLKPLKKDHIWVQHFEDRQGINTMFAENLPEFLKQLLK SYDNRMIIGDMKNELIGTFLKQEEWSKWWAKVKSVLKKEANIGMNPKKKDEVVYHEKPITHSETLTQKFQASNDANKKLE IAMEAVRDSDEAAEAGEFFISHYVEEESARDIIRKISAYLYLEEAGKAWPTEEFSHKIREPELKTLIQTLTKEDALKISK ALENTDIKKGFKDLIRSHHPEAINILIGLLFEVPVKVNRSVFQNLVADEKYAELNLFFETVCNKSKENPEVFLWVAKSIL SHTWKFDWLKVSEEDLVLRVFRILKPLAKIEDKGTKLKNQAMDILFGKDNSLLRDILTNADDEYVRKLFALFKEVPYVTD LEKDQLYALINELKPNIVWDEYDSEEDADDDPLANLPHDVVLVTRRAFNAKKLEFEHLVNVEMAENSRDIGEAQEKGDLR ENAEYKAAMEKQAQLQAAIKRLEAELKSARILDLSDVKTEKVGIGTTVRLKNKQTGESVTYSILGAWDADTEKNIISYQS PLAKSLLGKHTGNEATLVFGSTETVYEVLDIARYSMTGQEA
Sequences:
>Translated_921_residues MPETITEDKSNKIADNDKLTPLFNEEIYVRADAGTVPVSKFKIFDDVIDAYKAENRLAEAKQKIEDHFKEHPESISAKYM LMIISFMEDSMGDANLVKNILDSFKAHAKWTIIEYITDSILRFGDHRLALRVKAEALDKLKKNKELKVVLEKLAKQDRKN PEIAKKYGFSIMEEDKPKAMSYLKLAVEMYAKNKEYVPMEEIWPTIVQNNYEDVSFFDKIERILLGQREKTRLVGLLYPI VEPFKAMEDWDHVIYFLKKILEHEPASQKARNELIRSYKQKYVAHSLLEDFLKMSELGNNRKPVKLCITNFERNIVFDTG NYVMHRNWGVGKITSISQTGDSIFVDFEEKKDHKLSIQMAITSLKPLKKDHIWVQHFEDRQGINTMFAENLPEFLKQLLK SYDNRMIIGDMKNELIGTFLKQEEWSKWWAKVKSVLKKEANIGMNPKKKDEVVYHEKPITHSETLTQKFQASNDANKKLE IAMEAVRDSDEAAEAGEFFISHYVEEESARDIIRKISAYLYLEEAGKAWPTEEFSHKIREPELKTLIQTLTKEDALKISK ALENTDIKKGFKDLIRSHHPEAINILIGLLFEVPVKVNRSVFQNLVADEKYAELNLFFETVCNKSKENPEVFLWVAKSIL SHTWKFDWLKVSEEDLVLRVFRILKPLAKIEDKGTKLKNQAMDILFGKDNSLLRDILTNADDEYVRKLFALFKEVPYVTD LEKDQLYALINELKPNIVWDEYDSEEDADDDPLANLPHDVVLVTRRAFNAKKLEFEHLVNVEMAENSRDIGEAQEKGDLR ENAEYKAAMEKQAQLQAAIKRLEAELKSARILDLSDVKTEKVGIGTTVRLKNKQTGESVTYSILGAWDADTEKNIISYQS PLAKSLLGKHTGNEATLVFGSTETVYEVLDIARYSMTGQEA >Mature_920_residues PETITEDKSNKIADNDKLTPLFNEEIYVRADAGTVPVSKFKIFDDVIDAYKAENRLAEAKQKIEDHFKEHPESISAKYML MIISFMEDSMGDANLVKNILDSFKAHAKWTIIEYITDSILRFGDHRLALRVKAEALDKLKKNKELKVVLEKLAKQDRKNP EIAKKYGFSIMEEDKPKAMSYLKLAVEMYAKNKEYVPMEEIWPTIVQNNYEDVSFFDKIERILLGQREKTRLVGLLYPIV EPFKAMEDWDHVIYFLKKILEHEPASQKARNELIRSYKQKYVAHSLLEDFLKMSELGNNRKPVKLCITNFERNIVFDTGN YVMHRNWGVGKITSISQTGDSIFVDFEEKKDHKLSIQMAITSLKPLKKDHIWVQHFEDRQGINTMFAENLPEFLKQLLKS YDNRMIIGDMKNELIGTFLKQEEWSKWWAKVKSVLKKEANIGMNPKKKDEVVYHEKPITHSETLTQKFQASNDANKKLEI AMEAVRDSDEAAEAGEFFISHYVEEESARDIIRKISAYLYLEEAGKAWPTEEFSHKIREPELKTLIQTLTKEDALKISKA LENTDIKKGFKDLIRSHHPEAINILIGLLFEVPVKVNRSVFQNLVADEKYAELNLFFETVCNKSKENPEVFLWVAKSILS HTWKFDWLKVSEEDLVLRVFRILKPLAKIEDKGTKLKNQAMDILFGKDNSLLRDILTNADDEYVRKLFALFKEVPYVTDL EKDQLYALINELKPNIVWDEYDSEEDADDDPLANLPHDVVLVTRRAFNAKKLEFEHLVNVEMAENSRDIGEAQEKGDLRE NAEYKAAMEKQAQLQAAIKRLEAELKSARILDLSDVKTEKVGIGTTVRLKNKQTGESVTYSILGAWDADTEKNIISYQSP LAKSLLGKHTGNEATLVFGSTETVYEVLDIARYSMTGQEA
Specific function: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary
COG id: COG1747
COG function: function code S; Uncharacterized N-terminal domain of the transcription elongation factor GreA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 GRAD2 (greA associated 2) domain [H]
Homologues:
Organism=Escherichia coli, GI87082225, Length=152, Percent_Identity=34.8684210526316, Blast_Score=86, Evalue=8e-18,
Paralogues:
None
Copy number: 259 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018151 - InterPro: IPR011990 - InterPro: IPR006359 - InterPro: IPR001437 - InterPro: IPR022691 [H]
Pfam domain/function: PF01272 GreA_GreB; PF03449 GreA_GreB_N [H]
EC number: NA
Molecular weight: Translated: 106389; Mature: 106258
Theoretical pI: Translated: 5.89; Mature: 5.89
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPETITEDKSNKIADNDKLTPLFNEEIYVRADAGTVPVSKFKIFDDVIDAYKAENRLAEA CCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH KQKIEDHFKEHPESISAKYMLMIISFMEDSMGDANLVKNILDSFKAHAKWTIIEYITDSI HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH LRFGDHRLALRVKAEALDKLKKNKELKVVLEKLAKQDRKNPEIAKKYGFSIMEEDKPKAM HHHCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCCHHCCCCHHHH SYLKLAVEMYAKNKEYVPMEEIWPTIVQNNYEDVSFFDKIERILLGQREKTRLVGLLYPI HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH VEPFKAMEDWDHVIYFLKKILEHEPASQKARNELIRSYKQKYVAHSLLEDFLKMSELGNN HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC RKPVKLCITNFERNIVFDTGNYVMHRNWGVGKITSISQTGDSIFVDFEEKKDHKLSIQMA CCCCEEEEECCCCEEEEECCCEEEECCCCCCCCCEECCCCCEEEEEECCCCCCEEEEEEE ITSLKPLKKDHIWVQHFEDRQGINTMFAENLPEFLKQLLKSYDNRMIIGDMKNELIGTFL HHHHCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH KQEEWSKWWAKVKSVLKKEANIGMNPKKKDEVVYHEKPITHSETLTQKFQASNDANKKLE HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHH IAMEAVRDSDEAAEAGEFFISHYVEEESARDIIRKISAYLYLEEAGKAWPTEEFSHKIRE HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC PELKTLIQTLTKEDALKISKALENTDIKKGFKDLIRSHHPEAINILIGLLFEVPVKVNRS CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH VFQNLVADEKYAELNLFFETVCNKSKENPEVFLWVAKSILSHTWKFDWLKVSEEDLVLRV HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCEEEECHHHHHHHH FRILKPLAKIEDKGTKLKNQAMDILFGKDNSLLRDILTNADDEYVRKLFALFKEVPYVTD HHHHHHHHHHHHCCCHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC LEKDQLYALINELKPNIVWDEYDSEEDADDDPLANLPHDVVLVTRRAFNAKKLEFEHLVN CCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHEEEEHHHCCCHHCCHHHHHC VEMAENSRDIGEAQEKGDLRENAEYKAAMEKQAQLQAAIKRLEAELKSARILDLSDVKTE HHHHCCCCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHCCCHH KVGIGTTVRLKNKQTGESVTYSILGAWDADTEKNIISYQSPLAKSLLGKHTGNEATLVFG HCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC STETVYEVLDIARYSMTGQEA CHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure PETITEDKSNKIADNDKLTPLFNEEIYVRADAGTVPVSKFKIFDDVIDAYKAENRLAEA CCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH KQKIEDHFKEHPESISAKYMLMIISFMEDSMGDANLVKNILDSFKAHAKWTIIEYITDSI HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH LRFGDHRLALRVKAEALDKLKKNKELKVVLEKLAKQDRKNPEIAKKYGFSIMEEDKPKAM HHHCCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCCHHCCCCHHHH SYLKLAVEMYAKNKEYVPMEEIWPTIVQNNYEDVSFFDKIERILLGQREKTRLVGLLYPI HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH VEPFKAMEDWDHVIYFLKKILEHEPASQKARNELIRSYKQKYVAHSLLEDFLKMSELGNN HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC RKPVKLCITNFERNIVFDTGNYVMHRNWGVGKITSISQTGDSIFVDFEEKKDHKLSIQMA CCCCEEEEECCCCEEEEECCCEEEECCCCCCCCCEECCCCCEEEEEECCCCCCEEEEEEE ITSLKPLKKDHIWVQHFEDRQGINTMFAENLPEFLKQLLKSYDNRMIIGDMKNELIGTFL HHHHCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHH KQEEWSKWWAKVKSVLKKEANIGMNPKKKDEVVYHEKPITHSETLTQKFQASNDANKKLE HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHH IAMEAVRDSDEAAEAGEFFISHYVEEESARDIIRKISAYLYLEEAGKAWPTEEFSHKIRE HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC PELKTLIQTLTKEDALKISKALENTDIKKGFKDLIRSHHPEAINILIGLLFEVPVKVNRS CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHH VFQNLVADEKYAELNLFFETVCNKSKENPEVFLWVAKSILSHTWKFDWLKVSEEDLVLRV HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCCCCEEEECHHHHHHHH FRILKPLAKIEDKGTKLKNQAMDILFGKDNSLLRDILTNADDEYVRKLFALFKEVPYVTD HHHHHHHHHHHHCCCHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC LEKDQLYALINELKPNIVWDEYDSEEDADDDPLANLPHDVVLVTRRAFNAKKLEFEHLVN CCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHEEEEHHHCCCHHCCHHHHHC VEMAENSRDIGEAQEKGDLRENAEYKAAMEKQAQLQAAIKRLEAELKSARILDLSDVKTE HHHHCCCCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHCCCHH KVGIGTTVRLKNKQTGESVTYSILGAWDADTEKNIISYQSPLAKSLLGKHTGNEATLVFG HCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC STETVYEVLDIARYSMTGQEA CHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9403685 [H]