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The map label for this gene is fur [H]

Identifier: 183221703

GI number: 183221703

Start: 2401594

End: 2402073

Strand: Reverse

Name: fur [H]

Synonym: LEPBI_I2330

Alternate gene names: 183221703

Gene position: 2402073-2401594 (Counterclockwise)

Preceding gene: 183221704

Following gene: 183221702

Centisome position: 66.73

GC content: 35.83

Gene sequence:

>480_bases
TTGCAAAACGATCCAATTTCCTCCGAAGACACTAAAAAAGAAATGCTCGCCTTTGAGGAGTATCTCAAAGAAAAAGGTTT
AAAAATTACAAACCAACGTTTGTTAGTTGCGCAAAAGATTTTTTCTTCTCATAATCATTTTACTGCAGAAGGTTTGCTCG
ACGAACTGAAAGACAATAAAGACCGAATTTCTAAAGCGACCATTTATCGAATTTTGGCCATTATGGTGGAAGCGGGACTT
CTCGAAGAACACGATTTTGGAAAAGATTATAAATACTACGAACATATCATTGGGCATGAACACCATGATCATATCATTTG
TATGCAATGTGGTAGGACCGTAGAATTCATCGATGAAAGGATCGAAGAATTACAAAACAAAGCCGCTTCGGAAAATGGTT
TTACCATCACAGGCCATAGTTTGAATATTTTTGGCAATTGTACAAACTTTGCAACTTGCGAACATAAAAACAAAAAATAG

Upstream 100 bases:

>100_bases
AGGGTGATGGCTCTGAGAATTGCAGAAGAAGCAGAAAGAGCTTGGTATTATTCCATTTCTGGTGTATTGAATTAAGTTAC
GAATTTAGGAGATTTAACCC

Downstream 100 bases:

>100_bases
TGTCTTCTATTTTTAAAGAAGGTATTTACGATACAGGTTCTTATGCGAGGACTGGCACTTTAGATCTGAATGGCATCCAA
ATCCAAACTCCGATCTTTAT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQNDPISSEDTKKEMLAFEEYLKEKGLKITNQRLLVAQKIFSSHNHFTAEGLLDELKDNKDRISKATIYRILAIMVEAGL
LEEHDFGKDYKYYEHIIGHEHHDHIICMQCGRTVEFIDERIEELQNKAASENGFTITGHSLNIFGNCTNFATCEHKNKK

Sequences:

>Translated_159_residues
MQNDPISSEDTKKEMLAFEEYLKEKGLKITNQRLLVAQKIFSSHNHFTAEGLLDELKDNKDRISKATIYRILAIMVEAGL
LEEHDFGKDYKYYEHIIGHEHHDHIICMQCGRTVEFIDERIEELQNKAASENGFTITGHSLNIFGNCTNFATCEHKNKK
>Mature_159_residues
MQNDPISSEDTKKEMLAFEEYLKEKGLKITNQRLLVAQKIFSSHNHFTAEGLLDELKDNKDRISKATIYRILAIMVEAGL
LEEHDFGKDYKYYEHIIGHEHHDHIICMQCGRTVEFIDERIEELQNKAASENGFTITGHSLNIFGNCTNFATCEHKNKK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=37.5, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18401; Mature: 18401

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNDPISSEDTKKEMLAFEEYLKEKGLKITNQRLLVAQKIFSSHNHFTAEGLLDELKDNK
CCCCCCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHHCCH
DRISKATIYRILAIMVEAGLLEEHDFGKDYKYYEHIIGHEHHDHIICMQCGRTVEFIDER
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
IEELQNKAASENGFTITGHSLNIFGNCTNFATCEHKNKK
HHHHHHHHCCCCCCEEECCCEEEEECCCCCEECCCCCCC
>Mature Secondary Structure
MQNDPISSEDTKKEMLAFEEYLKEKGLKITNQRLLVAQKIFSSHNHFTAEGLLDELKDNK
CCCCCCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCCHHHHHHHHHCCH
DRISKATIYRILAIMVEAGLLEEHDFGKDYKYYEHIIGHEHHDHIICMQCGRTVEFIDER
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHH
IEELQNKAASENGFTITGHSLNIFGNCTNFATCEHKNKK
HHHHHHHHCCCCCCEEECCCEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200525 [H]