Click here to switch to the map view.

The map label for this gene is lipB [H]

Identifier: 183221669

GI number: 183221669

Start: 2363877

End: 2364419

Strand: Reverse

Name: lipB [H]

Synonym: LEPBI_I2294

Alternate gene names: 183221669

Gene position: 2364419-2363877 (Counterclockwise)

Preceding gene: 183221673

Following gene: 183221668

Centisome position: 65.68

GC content: 43.83

Gene sequence:

>543_bases
ATGCTCTTTTTAGAACACAGTCCATGTTTGACAGGAGGCATAGGCGCGAAAGCGGAAAATCTTTTGGTTTCTAAGGAGAG
ACTTGAAACATTGGGAGTTCACCTTGTCACACTCCCGCGCGGTGGGGACTTTACAGCCCACGAACCAGGCCAAATCGTAG
GTTACCTCCACATCGATCTGAAAAAACGAAATTTGAGTTTGGGGGATTTTTTACGAAACTTAAACGAGAGTTTGGTGGTA
GCAGTGAAAAGAACTTGGGGCCTTACCTTGGTGGAAAATCCGAAAGCACCAGGTTTGTACACGGAAGGGACAAATAAAAA
ACTCATCTCGGAAGGTGTGTATGCCAAATCTTATTTTACAAGTTTTGGTTTTGCTTTGAATGGGATCAATACTCTTGGTA
CTTTTTCTTTGATCAATCCATGTGGGGCACGTGCCAGTGATATGATATCCCTTGAAGCACTTGGACTTTCGGAGGGATTC
AGGGAAAAACGAAAGGAATTTGTTTTGCAATTCTCCCGCCACTTCCTCTCACTTCTCCCTTAA

Upstream 100 bases:

>100_bases
CCATCAAAAAGGACTACCTTCCTATCTCTTTCCTTCGATTGTACCCTACCAAAGATACTTGGATTTCCAGGAAAATTCCA
GGAAAAATCGAAGGGAATCC

Downstream 100 bases:

>100_bases
ATTCGAATTTCTTACGGCATTTCTTCGGATTTGGCCGAAAAGTAAAAGGGGGATCCATGAAATATTCACGTTTTTTTCTA
TCGTTTCTACTCTTTTTTAT

Product: lipoyltransferase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MLFLEHSPCLTGGIGAKAENLLVSKERLETLGVHLVTLPRGGDFTAHEPGQIVGYLHIDLKKRNLSLGDFLRNLNESLVV
AVKRTWGLTLVENPKAPGLYTEGTNKKLISEGVYAKSYFTSFGFALNGINTLGTFSLINPCGARASDMISLEALGLSEGF
REKRKEFVLQFSRHFLSLLP

Sequences:

>Translated_180_residues
MLFLEHSPCLTGGIGAKAENLLVSKERLETLGVHLVTLPRGGDFTAHEPGQIVGYLHIDLKKRNLSLGDFLRNLNESLVV
AVKRTWGLTLVENPKAPGLYTEGTNKKLISEGVYAKSYFTSFGFALNGINTLGTFSLINPCGARASDMISLEALGLSEGF
REKRKEFVLQFSRHFLSLLP
>Mature_180_residues
MLFLEHSPCLTGGIGAKAENLLVSKERLETLGVHLVTLPRGGDFTAHEPGQIVGYLHIDLKKRNLSLGDFLRNLNESLVV
AVKRTWGLTLVENPKAPGLYTEGTNKKLISEGVYAKSYFTSFGFALNGINTLGTFSLINPCGARASDMISLEALGLSEGF
REKRKEFVLQFSRHFLSLLP

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Escherichia coli, GI87081767, Length=151, Percent_Identity=31.7880794701987, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 19765; Mature: 19765

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLEHSPCLTGGIGAKAENLLVSKERLETLGVHLVTLPRGGDFTAHEPGQIVGYLHIDL
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEEEEEEE
KKRNLSLGDFLRNLNESLVVAVKRTWGLTLVENPKAPGLYTEGTNKKLISEGVYAKSYFT
ECCCCCHHHHHHCCCHHEEEEEECCCCEEEEECCCCCCEEECCCCCHHHHCCCHHHHHHH
SFGFALNGINTLGTFSLINPCGARASDMISLEALGLSEGFREKRKEFVLQFSRHFLSLLP
HHHHHHCCCCHHHHHHHCCCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFLEHSPCLTGGIGAKAENLLVSKERLETLGVHLVTLPRGGDFTAHEPGQIVGYLHIDL
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEEEEEEE
KKRNLSLGDFLRNLNESLVVAVKRTWGLTLVENPKAPGLYTEGTNKKLISEGVYAKSYFT
ECCCCCHHHHHHCCCHHEEEEEECCCCEEEEECCCCCCEEECCCCCHHHHCCCHHHHHHH
SFGFALNGINTLGTFSLINPCGARASDMISLEALGLSEGFREKRKEFVLQFSRHFLSLLP
HHHHHHCCCCHHHHHHHCCCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA