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The map label for this gene is malL [H]

Identifier: 183221659

GI number: 183221659

Start: 2349878

End: 2351329

Strand: Reverse

Name: malL [H]

Synonym: LEPBI_I2284

Alternate gene names: 183221659

Gene position: 2351329-2349878 (Counterclockwise)

Preceding gene: 183221661

Following gene: 183221658

Centisome position: 65.32

GC content: 36.85

Gene sequence:

>1452_bases
ATGGAAAACAAGATGGAATGGTGGAAACAAACTTCAATTTACCAGATTTACCCTTGGTCATTTCAGGATTCGAACGGGGA
TGGGATCGGTGATTTAGCGGGAATCCTTGGGCGTTTGGACGAGATTCAAGAATTAGGAGTTGAAACCATTTGGTTTTCTC
CTTTTTACCGAAGTCCAGGTGAGGACTTTGGTTATGATATTTCGGATTACACAACCATAGATCCAAGGTTTGGCACGATG
GCGGACACTGAACGGCTCATCAAAGAAATCCACAAACGAAAGATGAAAGTGGTCCTCGATATGGTGATGAACCACACTTC
AGACAAACACCCTTGGTTTTTGGAATCTAAGTCCTCTACTTCAAATCCGAAACGTGATTTTTACATTTGGAGAAAGGGTA
CAAAAAAACCACCCAATAATTGGATCTCCATGGTAGGCAAATCAGGATGGAATTACGATCCACAGACAGAAGAATACTAT
TACAGCAATTTTTTATCCTTCCAACCAGACCTAAATTATCGAAATCCTAAAGTCAAACAAACTATGTTGAAAGTTCTAGA
CTTTTGGTTACAAAAAGGCGTGGATGGATTTCGTCTTGATATCTTCAATTCAATTTATAAAGATGAAAGTTTTCGCGACA
ATCCATTTAGTTTACGTTTTTTCCCAACACCAGATAACCACGATGAGGCTTTTTTTCAAAAAAAGAAATACAACTTAAAC
TTATCGGAATCTTTTACGTTTGCCAAAGAAGTTCGAAAACACATTTCTAAATACAAACAAAAACCTTTCCTCATCGGTGA
AGTGAGTGGATCTGACACTATACTCAAATCATTTTTAGGAGAAAAATTAGATGGTCTCAATTTAGTATTCCAATTTGAAC
TGATCCATTTTCAATACAAATCAAAGTTCTTTCGAAATCTACTGGAAAAAAATGAAACCATATTTCCGAGTCCTTACACA
CCTACCTATGTATTAGGAAATCATGACCAGAGGCGTTATATAGATCGGTTAGGTGGAGACCAAAGGAAAGCAAAACTATT
AGCCTGTTTTCAGTTTATGGCAAGGGGAGTTCCGATCGTTTATTATGGTGAAGAAATAGGACTGAGAGAAGGAAAAATTT
CCAATTTTAAGGGCAAAGATCCAATTGCGAAAATGAATTCATTTGTTCCTTTATTTTTAAGTAATTTACTTGGGATTTAT
ATCAATCGTGACAATTGTCGTCTGCCAATGTTATGGGATGATTCGAAATATGGTGGATTCACAACGGGTGTACCTTGGTT
ACCGATCGGATCCATCAATCCAAAGAATACAGTATTGGAACAAAAAAAAACATTCAGACTCATTATGGAAACATTACCAA
ACTCTATTCCAACTACGAAAAAAATGGAAGGTGATCAGAGAGGGAAGTTTGAGAACAATTCCAACAGAGAAAGACGATGT
TCTGTGTTTTGA

Upstream 100 bases:

>100_bases
TGATTTTTTCTTTATCCATTGCTACCTGCTTGTATAAAGAACAGAAATTCGGTGATTAGGTAAGAAGCAACTGAAATAAC
AAAGGGGTGATAGAAAAGTC

Downstream 100 bases:

>100_bases
ACGTAGTCTGAAAGAAAACACGTTACGTGTGTTTTTAAACTTTGGAACAAAAGAAGTGCGTTTGACCTCCTTAGGAAAAG
GAAACGATTTGTATGTATTT

Product: putative O-glycosyl hydrolase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MENKMEWWKQTSIYQIYPWSFQDSNGDGIGDLAGILGRLDEIQELGVETIWFSPFYRSPGEDFGYDISDYTTIDPRFGTM
ADTERLIKEIHKRKMKVVLDMVMNHTSDKHPWFLESKSSTSNPKRDFYIWRKGTKKPPNNWISMVGKSGWNYDPQTEEYY
YSNFLSFQPDLNYRNPKVKQTMLKVLDFWLQKGVDGFRLDIFNSIYKDESFRDNPFSLRFFPTPDNHDEAFFQKKKYNLN
LSESFTFAKEVRKHISKYKQKPFLIGEVSGSDTILKSFLGEKLDGLNLVFQFELIHFQYKSKFFRNLLEKNETIFPSPYT
PTYVLGNHDQRRYIDRLGGDQRKAKLLACFQFMARGVPIVYYGEEIGLREGKISNFKGKDPIAKMNSFVPLFLSNLLGIY
INRDNCRLPMLWDDSKYGGFTTGVPWLPIGSINPKNTVLEQKKTFRLIMETLPNSIPTTKKMEGDQRGKFENNSNRERRC
SVF

Sequences:

>Translated_483_residues
MENKMEWWKQTSIYQIYPWSFQDSNGDGIGDLAGILGRLDEIQELGVETIWFSPFYRSPGEDFGYDISDYTTIDPRFGTM
ADTERLIKEIHKRKMKVVLDMVMNHTSDKHPWFLESKSSTSNPKRDFYIWRKGTKKPPNNWISMVGKSGWNYDPQTEEYY
YSNFLSFQPDLNYRNPKVKQTMLKVLDFWLQKGVDGFRLDIFNSIYKDESFRDNPFSLRFFPTPDNHDEAFFQKKKYNLN
LSESFTFAKEVRKHISKYKQKPFLIGEVSGSDTILKSFLGEKLDGLNLVFQFELIHFQYKSKFFRNLLEKNETIFPSPYT
PTYVLGNHDQRRYIDRLGGDQRKAKLLACFQFMARGVPIVYYGEEIGLREGKISNFKGKDPIAKMNSFVPLFLSNLLGIY
INRDNCRLPMLWDDSKYGGFTTGVPWLPIGSINPKNTVLEQKKTFRLIMETLPNSIPTTKKMEGDQRGKFENNSNRERRC
SVF
>Mature_483_residues
MENKMEWWKQTSIYQIYPWSFQDSNGDGIGDLAGILGRLDEIQELGVETIWFSPFYRSPGEDFGYDISDYTTIDPRFGTM
ADTERLIKEIHKRKMKVVLDMVMNHTSDKHPWFLESKSSTSNPKRDFYIWRKGTKKPPNNWISMVGKSGWNYDPQTEEYY
YSNFLSFQPDLNYRNPKVKQTMLKVLDFWLQKGVDGFRLDIFNSIYKDESFRDNPFSLRFFPTPDNHDEAFFQKKKYNLN
LSESFTFAKEVRKHISKYKQKPFLIGEVSGSDTILKSFLGEKLDGLNLVFQFELIHFQYKSKFFRNLLEKNETIFPSPYT
PTYVLGNHDQRRYIDRLGGDQRKAKLLACFQFMARGVPIVYYGEEIGLREGKISNFKGKDPIAKMNSFVPLFLSNLLGIY
INRDNCRLPMLWDDSKYGGFTTGVPWLPIGSINPKNTVLEQKKTFRLIMETLPNSIPTTKKMEGDQRGKFENNSNRERRC
SVF

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=451, Percent_Identity=32.1507760532151, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI61744475, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI65506891, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI61744477, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI61744479, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI61744481, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=9e-11,
Organism=Homo sapiens, GI61744483, Length=206, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790687, Length=473, Percent_Identity=34.2494714587738, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1786604, Length=369, Percent_Identity=23.8482384823848, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=37.3626373626374, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=474, Percent_Identity=26.3713080168776, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32565753, Length=392, Percent_Identity=27.2959183673469, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6322245, Length=475, Percent_Identity=35.5789473684211, Blast_Score=254, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6321726, Length=472, Percent_Identity=33.4745762711864, Blast_Score=234, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6319776, Length=488, Percent_Identity=34.8360655737705, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6321731, Length=488, Percent_Identity=34.6311475409836, Blast_Score=233, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6324416, Length=471, Percent_Identity=32.484076433121, Blast_Score=233, Evalue=6e-62,
Organism=Saccharomyces cerevisiae, GI6322241, Length=471, Percent_Identity=32.484076433121, Blast_Score=233, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6322021, Length=471, Percent_Identity=32.484076433121, Blast_Score=233, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24586591, Length=444, Percent_Identity=35.1351351351351, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI221330053, Length=465, Percent_Identity=34.4086021505376, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24583747, Length=448, Percent_Identity=37.2767857142857, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24583749, Length=448, Percent_Identity=37.2767857142857, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24583745, Length=474, Percent_Identity=33.3333333333333, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586593, Length=460, Percent_Identity=35.6521739130435, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24586589, Length=447, Percent_Identity=35.1230425055928, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586587, Length=446, Percent_Identity=33.6322869955157, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586597, Length=478, Percent_Identity=32.0083682008368, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24586599, Length=453, Percent_Identity=33.9955849889625, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI45549022, Length=464, Percent_Identity=33.6206896551724, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI281360393, Length=403, Percent_Identity=33.4987593052109, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 56728; Mature: 56728

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKMEWWKQTSIYQIYPWSFQDSNGDGIGDLAGILGRLDEIQELGVETIWFSPFYRSPG
CCCHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCC
EDFGYDISDYTTIDPRFGTMADTERLIKEIHKRKMKVVLDMVMNHTSDKHPWFLESKSST
CCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SNPKRDFYIWRKGTKKPPNNWISMVGKSGWNYDPQTEEYYYSNFLSFQPDLNYRNPKVKQ
CCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHH
TMLKVLDFWLQKGVDGFRLDIFNSIYKDESFRDNPFSLRFFPTPDNHDEAFFQKKKYNLN
HHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCC
LSESFTFAKEVRKHISKYKQKPFLIGEVSGSDTILKSFLGEKLDGLNLVFQFELIHFQYK
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEHHHHHHH
SKFFRNLLEKNETIFPSPYTPTYVLGNHDQRRYIDRLGGDQRKAKLLACFQFMARGVPIV
HHHHHHHHHCCCEECCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
YYGEEIGLREGKISNFKGKDPIAKMNSFVPLFLSNLLGIYINRDNCRLPMLWDDSKYGGF
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCE
TTGVPWLPIGSINPKNTVLEQKKTFRLIMETLPNSIPTTKKMEGDQRGKFENNSNRERRC
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SVF
CCC
>Mature Secondary Structure
MENKMEWWKQTSIYQIYPWSFQDSNGDGIGDLAGILGRLDEIQELGVETIWFSPFYRSPG
CCCHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCCC
EDFGYDISDYTTIDPRFGTMADTERLIKEIHKRKMKVVLDMVMNHTSDKHPWFLESKSST
CCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SNPKRDFYIWRKGTKKPPNNWISMVGKSGWNYDPQTEEYYYSNFLSFQPDLNYRNPKVKQ
CCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHH
TMLKVLDFWLQKGVDGFRLDIFNSIYKDESFRDNPFSLRFFPTPDNHDEAFFQKKKYNLN
HHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCC
LSESFTFAKEVRKHISKYKQKPFLIGEVSGSDTILKSFLGEKLDGLNLVFQFELIHFQYK
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEHHHHHHH
SKFFRNLLEKNETIFPSPYTPTYVLGNHDQRRYIDRLGGDQRKAKLLACFQFMARGVPIV
HHHHHHHHHCCCEECCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
YYGEEIGLREGKISNFKGKDPIAKMNSFVPLFLSNLLGIYINRDNCRLPMLWDDSKYGGF
EECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCE
TTGVPWLPIGSINPKNTVLEQKKTFRLIMETLPNSIPTTKKMEGDQRGKFENNSNRERRC
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SVF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120057; 8370659; 9193006 [H]