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The map label for this gene is mcpC [H]

Identifier: 183221649

GI number: 183221649

Start: 2342066

End: 2343190

Strand: Direct

Name: mcpC [H]

Synonym: LEPBI_I2274

Alternate gene names: 183221649

Gene position: 2342066-2343190 (Clockwise)

Preceding gene: 183221648

Following gene: 183221650

Centisome position: 65.06

GC content: 36.36

Gene sequence:

>1125_bases
ATGGATGATAATTATTCAAATTCGGGGATGCGAAAGCTCAAAGAACTAATAGATTCCTTTGGTGAAAGATCAAAAGAAAT
TGGTTCTGTTGCTTCGTCCATCCAACAAGTTGCCAAACAGACCAACTTACTCGCATTAAATGCCTCAATTGAAGCAGCAA
GAGCTGGTGAACATGGTAGAGGTTTTGAAATTGTCGCAAACGAAGTCACTAAATTATCATTTCAAACTTCAGAAGCCACT
AAAAAAATATCTGAAATTTTATCCAGGATCAATTTAGAAAATTCAGAAGCCAATGCAGACGTATTGGAAATGGAAAAACA
ATCCATCATAGAATATGCAGAATTATGGACAAATAATATAGCCAAAGAGCTTGAATCAAAATTTTATATCATGGCTACAT
CTTTATATGGGCTCAAATTTTTAATCCAAAGTTTGGTTCATGCCAATATTGGTATGAAACGAGAACACCTACTTTTAATT
TTACAAGAATATCTCATTCAAAATGAACAACAGTTAGCTTACGCAATCTGCTGCGAACCCAATGTAATAGATGAAAAAGA
CCACGAATATGCTGGGAAAGAAGGACATGACCCCAATGGAAGGTTTGTGCCTTACTGCCATCGACACACAGGAAGAATTT
CCATTGAACCATTACAAGGGTACGACGTTCCAGGAGAAAATGGATGGTATATTTTACCACGTGACCTTGGAGAAGATGTA
ATGATGGAACCTTACGATTATCCAATTGAAGGAAAAACGGTAAAGATGACAAGTCTTATGACAAATTTATTCCTTCATTC
AAAATTTGCAGGAATTTTAGGAGCAGACTTTTCACTGGAACAATTACAAAAGGAATTATCTCCCAAAAGATTATTTGGAA
TGGGGACAACTTCTCTTGTGACCTTCGAAGGCAATTTTGCATCTCATCCTGAGATTGAAAAATTAGGAACGAAAGTTGAC
GGGCTTTCAGCTGATGGAATGGATGCGATCCAAAAAGGAGAAAGTTATACTCATGTTGACACAAATCAAATCGTCCGAAT
CTTAAAACCAGTCCGAATTGGCCAGAGCAAACGACCATGGAGTATCCTTGTAGAATTTAATATTATTGCTGTTTTGAAAA
AGTAA

Upstream 100 bases:

>100_bases
CGAGAAACTATTTCGATTGCAACAAGCTGGATATCAATAAGGATCAATTGAACTCCGATATTCAATATAGACCAAAATCT
GATTTAGGGATGGCGATGGA

Downstream 100 bases:

>100_bases
TTCGTCTAAAGGATAATGGATAAAGCACAAGAAGAACAATTGGAATCTCAGATTGTCACTTTGTATCAAGAGAAAGATGA
ACTCGAAGCTGAACTTGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDDNYSNSGMRKLKELIDSFGERSKEIGSVASSIQQVAKQTNLLALNASIEAARAGEHGRGFEIVANEVTKLSFQTSEAT
KKISEILSRINLENSEANADVLEMEKQSIIEYAELWTNNIAKELESKFYIMATSLYGLKFLIQSLVHANIGMKREHLLLI
LQEYLIQNEQQLAYAICCEPNVIDEKDHEYAGKEGHDPNGRFVPYCHRHTGRISIEPLQGYDVPGENGWYILPRDLGEDV
MMEPYDYPIEGKTVKMTSLMTNLFLHSKFAGILGADFSLEQLQKELSPKRLFGMGTTSLVTFEGNFASHPEIEKLGTKVD
GLSADGMDAIQKGESYTHVDTNQIVRILKPVRIGQSKRPWSILVEFNIIAVLKK

Sequences:

>Translated_374_residues
MDDNYSNSGMRKLKELIDSFGERSKEIGSVASSIQQVAKQTNLLALNASIEAARAGEHGRGFEIVANEVTKLSFQTSEAT
KKISEILSRINLENSEANADVLEMEKQSIIEYAELWTNNIAKELESKFYIMATSLYGLKFLIQSLVHANIGMKREHLLLI
LQEYLIQNEQQLAYAICCEPNVIDEKDHEYAGKEGHDPNGRFVPYCHRHTGRISIEPLQGYDVPGENGWYILPRDLGEDV
MMEPYDYPIEGKTVKMTSLMTNLFLHSKFAGILGADFSLEQLQKELSPKRLFGMGTTSLVTFEGNFASHPEIEKLGTKVD
GLSADGMDAIQKGESYTHVDTNQIVRILKPVRIGQSKRPWSILVEFNIIAVLKK
>Mature_374_residues
MDDNYSNSGMRKLKELIDSFGERSKEIGSVASSIQQVAKQTNLLALNASIEAARAGEHGRGFEIVANEVTKLSFQTSEAT
KKISEILSRINLENSEANADVLEMEKQSIIEYAELWTNNIAKELESKFYIMATSLYGLKFLIQSLVHANIGMKREHLLLI
LQEYLIQNEQQLAYAICCEPNVIDEKDHEYAGKEGHDPNGRFVPYCHRHTGRISIEPLQGYDVPGENGWYILPRDLGEDV
MMEPYDYPIEGKTVKMTSLMTNLFLHSKFAGILGADFSLEQLQKELSPKRLFGMGTTSLVTFEGNFASHPEIEKLGTKVD
GLSADGMDAIQKGESYTHVDTNQIVRILKPVRIGQSKRPWSILVEFNIIAVLKK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=78, Percent_Identity=46.1538461538462, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789453, Length=101, Percent_Identity=35.6435643564356, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787690, Length=65, Percent_Identity=50.7692307692308, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788194, Length=60, Percent_Identity=55, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI2367378, Length=64, Percent_Identity=48.4375, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 42022; Mature: 42022

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNYSNSGMRKLKELIDSFGERSKEIGSVASSIQQVAKQTNLLALNASIEAARAGEHGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCC
GFEIVANEVTKLSFQTSEATKKISEILSRINLENSEANADVLEMEKQSIIEYAELWTNNI
CHHHHHHHHHHHEECHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AKELESKFYIMATSLYGLKFLIQSLVHANIGMKREHLLLILQEYLIQNEQQLAYAICCEP
HHHHHCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCC
NVIDEKDHEYAGKEGHDPNGRFVPYCHRHTGRISIEPLQGYDVPGENGWYILPRDLGEDV
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEECCCCCCCC
MMEPYDYPIEGKTVKMTSLMTNLFLHSKFAGILGADFSLEQLQKELSPKRLFGMGTTSLV
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHEECCCCCEEE
TFEGNFASHPEIEKLGTKVDGLSADGMDAIQKGESYTHVDTNQIVRILKPVRIGQSKRPW
EEECCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCCCEECCHHHHHHHHHHHHCCCCCCCE
SILVEFNIIAVLKK
EEEEEEEEEEEECC
>Mature Secondary Structure
MDDNYSNSGMRKLKELIDSFGERSKEIGSVASSIQQVAKQTNLLALNASIEAARAGEHGR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCC
GFEIVANEVTKLSFQTSEATKKISEILSRINLENSEANADVLEMEKQSIIEYAELWTNNI
CHHHHHHHHHHHEECHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AKELESKFYIMATSLYGLKFLIQSLVHANIGMKREHLLLILQEYLIQNEQQLAYAICCEP
HHHHHCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCC
NVIDEKDHEYAGKEGHDPNGRFVPYCHRHTGRISIEPLQGYDVPGENGWYILPRDLGEDV
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEECCCCCCCC
MMEPYDYPIEGKTVKMTSLMTNLFLHSKFAGILGADFSLEQLQKELSPKRLFGMGTTSLV
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHEECCCCCEEE
TFEGNFASHPEIEKLGTKVDGLSADGMDAIQKGESYTHVDTNQIVRILKPVRIGQSKRPW
EEECCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCCCEECCHHHHHHHHHHHHCCCCCCCE
SILVEFNIIAVLKK
EEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]