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The map label for this gene is sspA [H]

Identifier: 183221291

GI number: 183221291

Start: 1999517

End: 2000188

Strand: Direct

Name: sspA [H]

Synonym: LEPBI_I1908

Alternate gene names: 183221291

Gene position: 1999517-2000188 (Clockwise)

Preceding gene: 183221290

Following gene: 183221292

Centisome position: 55.55

GC content: 38.24

Gene sequence:

>672_bases
ATGACAAAACCAACTCTTGTGAGCTTTAAACTTTGCCCTTACGTGCAACGTTCCGTGATCAACCTTTTAGAAAAAAAAGT
AGAGTATGAAATCAAATACATTGACCTAGCAAACAAACCAGATTGGTTTTTGAAAATTTCTCCTTTTGGAAGAGTACCAG
TACTCGTGGTAGGTGAGGAAGTACTGTTTGAATCGGCTGTCATCAACGAGTATTTAGATGAAACGAATCTACCTTCTCTC
CACCCTAAAGACCCATTACTAAAAGCGAAACATAGAGCCTGGGCAGAATTTGCCAGTGCTTTGTTAGTAGACCAATACGG
TTGGACCATGTCGAAGGAAGAAAGTGACTCCAATAAAAAAAAGGAAGAGATCCTTTCTAAATTCAAAATCCTCGAATCCA
TTTTACCAGAGCCAAAAAATGGCACCTTATTCTTTGCTGGTGAAACCAAACATCTCGTCGACACAGCCTATGCCCCGTTT
TTTATGAGAATGGAGTTTTTAAAAAACAAGGGAGTAGAATTTGATTTGGTGAGTGGTTTTCCAAAAGTACAAACTTGGAG
TGATACCTTACTTTCTTTGCCTTCTGTAAAGAATTCTGTTTTACCAGAAGTGCCAAAAGAATACATTGAATTTATCAAAG
CCCACAACTCATGGATGGGAGGAAAATTATAG

Upstream 100 bases:

>100_bases
AACAACACAGAAAAGTTTACTCAGTCCTTGGCCCTGAATTCAAAAAGGGATTACATGCCTTAGAAATGGACCTTTCCGCA
CCAAAAGGAGTCTAAATGAT

Downstream 100 bases:

>100_bases
GATGACCATTCCAGAAATCCAAAAAAAAATCGAAGAAGGATTACCAGGTTGTACTGTAGAAATTTTAGATCCCTACCGTG
ATGGTGTCCATATCAAAGCA

Product: putative glutathione S-transferase protein

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTKPTLVSFKLCPYVQRSVINLLEKKVEYEIKYIDLANKPDWFLKISPFGRVPVLVVGEEVLFESAVINEYLDETNLPSL
HPKDPLLKAKHRAWAEFASALLVDQYGWTMSKEESDSNKKKEEILSKFKILESILPEPKNGTLFFAGETKHLVDTAYAPF
FMRMEFLKNKGVEFDLVSGFPKVQTWSDTLLSLPSVKNSVLPEVPKEYIEFIKAHNSWMGGKL

Sequences:

>Translated_223_residues
MTKPTLVSFKLCPYVQRSVINLLEKKVEYEIKYIDLANKPDWFLKISPFGRVPVLVVGEEVLFESAVINEYLDETNLPSL
HPKDPLLKAKHRAWAEFASALLVDQYGWTMSKEESDSNKKKEEILSKFKILESILPEPKNGTLFFAGETKHLVDTAYAPF
FMRMEFLKNKGVEFDLVSGFPKVQTWSDTLLSLPSVKNSVLPEVPKEYIEFIKAHNSWMGGKL
>Mature_222_residues
TKPTLVSFKLCPYVQRSVINLLEKKVEYEIKYIDLANKPDWFLKISPFGRVPVLVVGEEVLFESAVINEYLDETNLPSLH
PKDPLLKAKHRAWAEFASALLVDQYGWTMSKEESDSNKKKEEILSKFKILESILPEPKNGTLFFAGETKHLVDTAYAPFF
MRMEFLKNKGVEFDLVSGFPKVQTWSDTLLSLPSVKNSVLPEVPKEYIEFIKAHNSWMGGKL

Specific function: Forms an equimolar complex with the RNA polymerase holoenzyme (RNAP) but not with the core enzyme [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4758484, Length=194, Percent_Identity=33.5051546391753, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI300360534, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI38016131, Length=195, Percent_Identity=29.7435897435897, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI300360569, Length=191, Percent_Identity=29.8429319371728, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI300360532, Length=194, Percent_Identity=30.4123711340206, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI300360567, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144449, Length=198, Percent_Identity=28.2828282828283, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193207701, Length=203, Percent_Identity=31.0344827586207, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115532656, Length=228, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532652, Length=228, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355775, Length=198, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21355763, Length=204, Percent_Identity=34.3137254901961, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355779, Length=229, Percent_Identity=33.1877729257642, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660979, Length=207, Percent_Identity=29.951690821256, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355765, Length=206, Percent_Identity=29.126213592233, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 25561; Mature: 25430

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPTLVSFKLCPYVQRSVINLLEKKVEYEIKYIDLANKPDWFLKISPFGRVPVLVVGEE
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCCCCEEEECHH
VLFESAVINEYLDETNLPSLHPKDPLLKAKHRAWAEFASALLVDQYGWTMSKEESDSNKK
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KEEILSKFKILESILPEPKNGTLFFAGETKHLVDTAYAPFFMRMEFLKNKGVEFDLVSGF
HHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PKVQTWSDTLLSLPSVKNSVLPEVPKEYIEFIKAHNSWMGGKL
CCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKPTLVSFKLCPYVQRSVINLLEKKVEYEIKYIDLANKPDWFLKISPFGRVPVLVVGEE
CCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCCCCEEEECHH
VLFESAVINEYLDETNLPSLHPKDPLLKAKHRAWAEFASALLVDQYGWTMSKEESDSNKK
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KEEILSKFKILESILPEPKNGTLFFAGETKHLVDTAYAPFFMRMEFLKNKGVEFDLVSGF
HHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PKVQTWSDTLLSLPSVKNSVLPEVPKEYIEFIKAHNSWMGGKL
CCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]