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The map label for this gene is yfeA [H]

Identifier: 183221266

GI number: 183221266

Start: 1974642

End: 1976312

Strand: Direct

Name: yfeA [H]

Synonym: LEPBI_I1882

Alternate gene names: 183221266

Gene position: 1974642-1976312 (Clockwise)

Preceding gene: 183221263

Following gene: 183221268

Centisome position: 54.86

GC content: 38.78

Gene sequence:

>1671_bases
TTGAACGAAAAACCTTACATCTTATGCATCGATGATGAATTCTTTATTCTTTGGAATCTCAAGGAACAATTGAAAAAAGT
TTTTGGCACAAGTTTTACGATCGAAACCGCTGAAAGTGCGGAAGCGGCGAAGGAAATCATCAAAGAAATTGATACGGCAA
ATGCCGATTTATGTGTGGTGATCTGTGATCATGTGATGCCCGGTCAAAAAGGGGACGAATTTCTCATTGAAATGCAAAAA
ACCCATCCCCGCACAAAAAAAATCATGTTAACGGGACAAGCCCCCGCCCAGGCCATAGGGAATGCACTGAACCATGGTTG
TTTGTATCGTTACCTTTCGAAACCATGGGATGCTCATGACTTAGAGCTCACCATCAAACAAGCAATTGATGCCTATTTCC
AAGAAAAATCCTTAGAAGAAAAAAACAAAGAATTAGCAGACACTCTCTATTACCATCGGGATACCAAATACCCTAATTTT
GAATCCTTAGTGAAAGAACTAAAGGGAAATAACCTATCCAATACCAACCAATCGATATTACTCCTGAAAATCGTCACTTT
CCCAACCATCATCAAGACCTTTGGAATCGAAGTGTACAGAAAAATCTTTCGAAAGGTATTACAACTCCTTTCCGTCCATT
TACAAAATGAACACAAGGTCTTTCATTTATATTCTGATGAAATCGCAATTTTATCAAATCTATCAGAGCAAGCGTTAGTC
GATGCAGTCCGAAGTTTTCGAATGATCTTAAAATCTGATGAATTTTTCTTAGATGGTGTTGGATTCCATTTGGACTGCCG
TTATGCTTCCGCATCTGGCCAAGAGGATTGTTATTATAAAGCCAAACTGGCACTCTTCCAAGCAGAATTCCAAAACACAA
TGGACTTCGTCTCGTACACAGAAGATTTGTCTACCGACCACCATTTACAAAATTTCCAAGTCAGCCAAAAGATCCACACC
GCCATTAGCCAAAAAAATATAATCCCTTACTTCCAAGGAATTTTGGACAACCAAACCAAAGAAATACGAAAGTTTGAATG
TTTGGCGCGGATTCGAGACCGAGATACCATCTTAACTCCCGATGTATTTCTAAAACTTGCAAAAGTCACCGGAAGCATTC
GAATGATCGGATTACAAATGATAGATGAATCGATGCAGTATTTCTCCAATCATCCATACGATTTTTCTATCAACTTGACC
GAATCGGAATTGGAATACAAAAGTTTTAGCAAATGGGTGGAATCAAGACTCTCGCAATACAAAATTGATCCGACTCGGGT
CACGTTTGAGATCTTAGAAGACATTAGTTTTTCAGAACACAAACATAGTTTGTCTACAATTAAGGACTTAAAAACCATTG
GTTGCCAAATTGCGATCGATGATTTTGGAGTTCAGTATTCCAATTTATCTCGTTTATTGGAATTCAATCCTGATTTTCTA
AAAATCGATGGAAAGTTTATCAAAAACCTCCCTGAAAACAAAACGGCTTATCTTCTTGTCCAGGGGATTGTTGAACTTGC
TCGTGGGATTGGAGCCAAAGTAGTAGCTGAGTTTGTGGATCGCCCCGCCATACAAGACTTAGTGGAATCCTTGGGAATTG
AATATTCCCAAGGTTATCTGTTTATGAAACCTTCTGCTGCGATTCCAGAAGCATCTAGTTTAAAGTTGTAA

Upstream 100 bases:

>100_bases
CGGCTTGATTAGATAGAATTGGTAGAAATTGTCAACTGGAAATAATTCTTGCATAATCTGGAGATTCAGATTCATTTGAG
ACGCTTCTCCAGGTATCCCA

Downstream 100 bases:

>100_bases
GGTCACACCAAAGTTCACTTGCCGGAAGGGACCAGGTTGGATCCCTTCTGGGAGTCTTGAAGAAATGTATTTTCTATCCT
GTAAGTTTTTGCCCGAAACA

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNEKPYILCIDDEFFILWNLKEQLKKVFGTSFTIETAESAEAAKEIIKEIDTANADLCVVICDHVMPGQKGDEFLIEMQK
THPRTKKIMLTGQAPAQAIGNALNHGCLYRYLSKPWDAHDLELTIKQAIDAYFQEKSLEEKNKELADTLYYHRDTKYPNF
ESLVKELKGNNLSNTNQSILLLKIVTFPTIIKTFGIEVYRKIFRKVLQLLSVHLQNEHKVFHLYSDEIAILSNLSEQALV
DAVRSFRMILKSDEFFLDGVGFHLDCRYASASGQEDCYYKAKLALFQAEFQNTMDFVSYTEDLSTDHHLQNFQVSQKIHT
AISQKNIIPYFQGILDNQTKEIRKFECLARIRDRDTILTPDVFLKLAKVTGSIRMIGLQMIDESMQYFSNHPYDFSINLT
ESELEYKSFSKWVESRLSQYKIDPTRVTFEILEDISFSEHKHSLSTIKDLKTIGCQIAIDDFGVQYSNLSRLLEFNPDFL
KIDGKFIKNLPENKTAYLLVQGIVELARGIGAKVVAEFVDRPAIQDLVESLGIEYSQGYLFMKPSAAIPEASSLKL

Sequences:

>Translated_556_residues
MNEKPYILCIDDEFFILWNLKEQLKKVFGTSFTIETAESAEAAKEIIKEIDTANADLCVVICDHVMPGQKGDEFLIEMQK
THPRTKKIMLTGQAPAQAIGNALNHGCLYRYLSKPWDAHDLELTIKQAIDAYFQEKSLEEKNKELADTLYYHRDTKYPNF
ESLVKELKGNNLSNTNQSILLLKIVTFPTIIKTFGIEVYRKIFRKVLQLLSVHLQNEHKVFHLYSDEIAILSNLSEQALV
DAVRSFRMILKSDEFFLDGVGFHLDCRYASASGQEDCYYKAKLALFQAEFQNTMDFVSYTEDLSTDHHLQNFQVSQKIHT
AISQKNIIPYFQGILDNQTKEIRKFECLARIRDRDTILTPDVFLKLAKVTGSIRMIGLQMIDESMQYFSNHPYDFSINLT
ESELEYKSFSKWVESRLSQYKIDPTRVTFEILEDISFSEHKHSLSTIKDLKTIGCQIAIDDFGVQYSNLSRLLEFNPDFL
KIDGKFIKNLPENKTAYLLVQGIVELARGIGAKVVAEFVDRPAIQDLVESLGIEYSQGYLFMKPSAAIPEASSLKL
>Mature_556_residues
MNEKPYILCIDDEFFILWNLKEQLKKVFGTSFTIETAESAEAAKEIIKEIDTANADLCVVICDHVMPGQKGDEFLIEMQK
THPRTKKIMLTGQAPAQAIGNALNHGCLYRYLSKPWDAHDLELTIKQAIDAYFQEKSLEEKNKELADTLYYHRDTKYPNF
ESLVKELKGNNLSNTNQSILLLKIVTFPTIIKTFGIEVYRKIFRKVLQLLSVHLQNEHKVFHLYSDEIAILSNLSEQALV
DAVRSFRMILKSDEFFLDGVGFHLDCRYASASGQEDCYYKAKLALFQAEFQNTMDFVSYTEDLSTDHHLQNFQVSQKIHT
AISQKNIIPYFQGILDNQTKEIRKFECLARIRDRDTILTPDVFLKLAKVTGSIRMIGLQMIDESMQYFSNHPYDFSINLT
ESELEYKSFSKWVESRLSQYKIDPTRVTFEILEDISFSEHKHSLSTIKDLKTIGCQIAIDDFGVQYSNLSRLLEFNPDFL
KIDGKFIKNLPENKTAYLLVQGIVELARGIGAKVVAEFVDRPAIQDLVESLGIEYSQGYLFMKPSAAIPEASSLKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082096, Length=413, Percent_Identity=29.0556900726392, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788849, Length=412, Percent_Identity=28.6407766990291, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790496, Length=234, Percent_Identity=31.1965811965812, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787055, Length=442, Percent_Identity=25.1131221719457, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081743, Length=247, Percent_Identity=29.1497975708502, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=21.9399538106236, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786507, Length=266, Percent_Identity=25.5639097744361, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI226510982, Length=224, Percent_Identity=24.1071428571429, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081921, Length=234, Percent_Identity=26.4957264957265, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081845, Length=235, Percent_Identity=25.1063829787234, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788502, Length=237, Percent_Identity=24.8945147679325, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787410, Length=133, Percent_Identity=33.0827067669173, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895 [H]

Pfam domain/function: PF00563 EAL; PF05231 MASE1 [H]

EC number: NA

Molecular weight: Translated: 63825; Mature: 63825

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKPYILCIDDEFFILWNLKEQLKKVFGTSFTIETAESAEAAKEIIKEIDTANADLCVV
CCCCCEEEEECCCEEEEECHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCCEEEE
ICDHVMPGQKGDEFLIEMQKTHPRTKKIMLTGQAPAQAIGNALNHGCLYRYLSKPWDAHD
EECCCCCCCCCCHHHHEEHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCH
LELTIKQAIDAYFQEKSLEEKNKELADTLYYHRDTKYPNFESLVKELKGNNLSNTNQSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEE
LLKIVTFPTIIKTFGIEVYRKIFRKVLQLLSVHLQNEHKVFHLYSDEIAILSNLSEQALV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCHHHHHH
DAVRSFRMILKSDEFFLDGVGFHLDCRYASASGQEDCYYKAKLALFQAEFQNTMDFVSYT
HHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EDLSTDHHLQNFQVSQKIHTAISQKNIIPYFQGILDNQTKEIRKFECLARIRDRDTILTP
HHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECH
DVFLKLAKVTGSIRMIGLQMIDESMQYFSNHPYDFSINLTESELEYKSFSKWVESRLSQY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
KIDPTRVTFEILEDISFSEHKHSLSTIKDLKTIGCQIAIDDFGVQYSNLSRLLEFNPDFL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEE
KIDGKFIKNLPENKTAYLLVQGIVELARGIGAKVVAEFVDRPAIQDLVESLGIEYSQGYL
EECCHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCEECCCEE
FMKPSAAIPEASSLKL
EECCCCCCCCCCCCCC
>Mature Secondary Structure
MNEKPYILCIDDEFFILWNLKEQLKKVFGTSFTIETAESAEAAKEIIKEIDTANADLCVV
CCCCCEEEEECCCEEEEECHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCCCCEEEE
ICDHVMPGQKGDEFLIEMQKTHPRTKKIMLTGQAPAQAIGNALNHGCLYRYLSKPWDAHD
EECCCCCCCCCCHHHHEEHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCH
LELTIKQAIDAYFQEKSLEEKNKELADTLYYHRDTKYPNFESLVKELKGNNLSNTNQSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEE
LLKIVTFPTIIKTFGIEVYRKIFRKVLQLLSVHLQNEHKVFHLYSDEIAILSNLSEQALV
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCHHHHHH
DAVRSFRMILKSDEFFLDGVGFHLDCRYASASGQEDCYYKAKLALFQAEFQNTMDFVSYT
HHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EDLSTDHHLQNFQVSQKIHTAISQKNIIPYFQGILDNQTKEIRKFECLARIRDRDTILTP
HHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECH
DVFLKLAKVTGSIRMIGLQMIDESMQYFSNHPYDFSINLTESELEYKSFSKWVESRLSQY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
KIDPTRVTFEILEDISFSEHKHSLSTIKDLKTIGCQIAIDDFGVQYSNLSRLLEFNPDFL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCEE
KIDGKFIKNLPENKTAYLLVQGIVELARGIGAKVVAEFVDRPAIQDLVESLGIEYSQGYL
EECCHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHCCCEECCCEE
FMKPSAAIPEASSLKL
EECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2201776 [H]