Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 183221145

GI number: 183221145

Start: 1837520

End: 1838632

Strand: Reverse

Name: mraY

Synonym: LEPBI_I1759

Alternate gene names: 183221145

Gene position: 1838632-1837520 (Counterclockwise)

Preceding gene: 183221146

Following gene: 183221144

Centisome position: 51.08

GC content: 39.35

Gene sequence:

>1113_bases
ATGTTCCAATGGATTTATGAATCATTTGGTAATGATTATGGTTTTTTAAGAGTGTTTAGTTATGTAACCCTTCGGGCAAT
GATGGCGGGACTTACGTCTATGTTCATTACCTTTATTTTTGGAAAATCTCTTATTTCGTTTTTGCTTTCCTTAAAATTCC
GAGAGTCGGTTCGAAATGATGGACCCCAGTCCCATGCTAACAAATCGGGAACCCCAACCATGGGTGGTTTGATCATGATC
TTATCACTCACCATCTCAACTCTGTTATGGGGTAATTTGTCTAATTGGAATGTGATTTTACTCCTTATCTCAGCTATCCT
TTTTGCAGGCCTTGGATTTACAGACGATTATATGAAATCTGTAAAAAAAATAAAAGGTGGGATGAGAGCTCGTACCAAAT
TCATCGTGACGATACTTTTTGCTGTGACGATTACCACCTTGTATTTTTATTATACAGGTAAATCAAATGTGAATCTTCAA
AAAGGAATCGTTTTTTCTATTACCGATTTGTTTTTACCATTTGTGAAAGGACCTGTTTGGAACTTAGGTATATTTGCAGT
TCCATTCGCCATTATCGTGTTAATCGGAAGTTCTCATGCTGTGAATTTAACAGATGGATTGGATGGGTTGGCTTCTGGAA
CTGTAGTCATCTCCACGGCAACATTTGCTTTGATTGCTTATGTTTCTGGAACTCCTTCGGCAGCAAACTATTTGCATATT
CCGTATCTTCCAGGTTCCCATGAATATTCCGTATTTCTTGCTGGCCTTTCCGGTGCGTTACTTGGTTTCCTATGGTTCAA
TTGCCACCCAGCGCAAGTGTTTATGGGTGATACAGGTTCCTTGTTTTTAGGATCCACCTTGGGTCTAGTTGCCATTATGT
TAAAAAAAGAAATCCTACTTGTCATCCTCGGTGGAATCTTTGTTGCAGAGGCTGTTAGCGTGATTTTGCAAGTGGGATCG
TTTAAACTGACGGGAAAACGGATTTTTAAAATGGCGCCTTTGCACCATCATTTTGAACTTTCCGGTTGGTCAGAAGAGAA
GGTGGTGATTCGGTTTTGGATCATTGGGATCATTCTTGCGATCATCACACTCTCTACCTTAAAAATCCAATAA

Upstream 100 bases:

>100_bases
ACTTACCAAATCATCGGCAAAGAAAAAACCAATTTTGTCGACTTTTTAGAAATTGAAAATGCGTTTTTAAATTTAGATAC
CGGGTTATAGAGGATTTAGT

Downstream 100 bases:

>100_bases
TGGAATTGATTCGAAATTTTCGAAATTTATTTCGATATGGAGCATCCCGATTTGATGCTCCCATGCTTTTTTTTATGTTT
TTGTTATTTGGAATGGGAAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MFQWIYESFGNDYGFLRVFSYVTLRAMMAGLTSMFITFIFGKSLISFLLSLKFRESVRNDGPQSHANKSGTPTMGGLIMI
LSLTISTLLWGNLSNWNVILLLISAILFAGLGFTDDYMKSVKKIKGGMRARTKFIVTILFAVTITTLYFYYTGKSNVNLQ
KGIVFSITDLFLPFVKGPVWNLGIFAVPFAIIVLIGSSHAVNLTDGLDGLASGTVVISTATFALIAYVSGTPSAANYLHI
PYLPGSHEYSVFLAGLSGALLGFLWFNCHPAQVFMGDTGSLFLGSTLGLVAIMLKKEILLVILGGIFVAEAVSVILQVGS
FKLTGKRIFKMAPLHHHFELSGWSEEKVVIRFWIIGIILAIITLSTLKIQ

Sequences:

>Translated_370_residues
MFQWIYESFGNDYGFLRVFSYVTLRAMMAGLTSMFITFIFGKSLISFLLSLKFRESVRNDGPQSHANKSGTPTMGGLIMI
LSLTISTLLWGNLSNWNVILLLISAILFAGLGFTDDYMKSVKKIKGGMRARTKFIVTILFAVTITTLYFYYTGKSNVNLQ
KGIVFSITDLFLPFVKGPVWNLGIFAVPFAIIVLIGSSHAVNLTDGLDGLASGTVVISTATFALIAYVSGTPSAANYLHI
PYLPGSHEYSVFLAGLSGALLGFLWFNCHPAQVFMGDTGSLFLGSTLGLVAIMLKKEILLVILGGIFVAEAVSVILQVGS
FKLTGKRIFKMAPLHHHFELSGWSEEKVVIRFWIIGIILAIITLSTLKIQ
>Mature_370_residues
MFQWIYESFGNDYGFLRVFSYVTLRAMMAGLTSMFITFIFGKSLISFLLSLKFRESVRNDGPQSHANKSGTPTMGGLIMI
LSLTISTLLWGNLSNWNVILLLISAILFAGLGFTDDYMKSVKKIKGGMRARTKFIVTILFAVTITTLYFYYTGKSNVNLQ
KGIVFSITDLFLPFVKGPVWNLGIFAVPFAIIVLIGSSHAVNLTDGLDGLASGTVVISTATFALIAYVSGTPSAANYLHI
PYLPGSHEYSVFLAGLSGALLGFLWFNCHPAQVFMGDTGSLFLGSTLGLVAIMLKKEILLVILGGIFVAEAVSVILQVGS
FKLTGKRIFKMAPLHHHFELSGWSEEKVVIRFWIIGIILAIITLSTLKIQ

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=370, Percent_Identity=46.7567567567568, Blast_Score=327, Evalue=9e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_LEPBA (B0S986)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001962791.1
- GeneID:   6388296
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_1706
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- ProtClustDB:   PRK00108
- BioCyc:   LBIF355278:LBF_1706-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 40504; Mature: 40504

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b744dd4)-; HASH(0x18aceb28)-; HASH(0x1b4701c0)-; HASH(0x40859af4)-; HASH(0x1aafb8ec)-; HASH(0x1bbc81c4)-; HASH(0x1bbc0194)-; HASH(0x1bbc80bc)-; HASH(0x1bbbd3d8)-; HASH(0x1b74a8d0)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQWIYESFGNDYGFLRVFSYVTLRAMMAGLTSMFITFIFGKSLISFLLSLKFRESVRND
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPQSHANKSGTPTMGGLIMILSLTISTLLWGNLSNWNVILLLISAILFAGLGFTDDYMKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VKKIKGGMRARTKFIVTILFAVTITTLYFYYTGKSNVNLQKGIVFSITDLFLPFVKGPVW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCC
NLGIFAVPFAIIVLIGSSHAVNLTDGLDGLASGTVVISTATFALIAYVSGTPSAANYLHI
CCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEE
PYLPGSHEYSVFLAGLSGALLGFLWFNCHPAQVFMGDTGSLFLGSTLGLVAIMLKKEILL
CCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
VILGGIFVAEAVSVILQVGSFKLTGKRIFKMAPLHHHFELSGWSEEKVVIRFWIIGIILA
HHHHHHHHHHHHHHHHHHCCEEECHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
IITLSTLKIQ
HHHHHHHCCH
>Mature Secondary Structure
MFQWIYESFGNDYGFLRVFSYVTLRAMMAGLTSMFITFIFGKSLISFLLSLKFRESVRND
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GPQSHANKSGTPTMGGLIMILSLTISTLLWGNLSNWNVILLLISAILFAGLGFTDDYMKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VKKIKGGMRARTKFIVTILFAVTITTLYFYYTGKSNVNLQKGIVFSITDLFLPFVKGPVW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEHHHHHHHHHHCCCCC
NLGIFAVPFAIIVLIGSSHAVNLTDGLDGLASGTVVISTATFALIAYVSGTPSAANYLHI
CCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEE
PYLPGSHEYSVFLAGLSGALLGFLWFNCHPAQVFMGDTGSLFLGSTLGLVAIMLKKEILL
CCCCCCCCCEEEEECHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
VILGGIFVAEAVSVILQVGSFKLTGKRIFKMAPLHHHFELSGWSEEKVVIRFWIIGIILA
HHHHHHHHHHHHHHHHHHCCEEECHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
IITLSTLKIQ
HHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA