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The map label for this gene is yciR [C]

Identifier: 183221125

GI number: 183221125

Start: 1814172

End: 1816280

Strand: Reverse

Name: yciR [C]

Synonym: LEPBI_I1739

Alternate gene names: 183221125

Gene position: 1816280-1814172 (Counterclockwise)

Preceding gene: 183221128

Following gene: 183221124

Centisome position: 50.46

GC content: 38.22

Gene sequence:

>2109_bases
ATGGGAAGCCCAATCAGTGTATTAATCTTAGAAAACGATTCCAGTAGCGTTTTCGATATCGTTCGTGAAATGAAGGCAAA
TGGCCTTAGCCCACTTTACAAGGTTGTGGAATCGTTTGGTTCGTTCGAATCGACTGTATTAGAAGAGGATTGGGATGCCA
TCCTATGTAGCACACGAAAACCCTTTCATTTAGAAATCTCTTTGTATCTAAAATTCTTAAATGAAAAAAAAATCGACATC
CCTGTCATTTTAATCTCCGACCAAGAAGACTTTCAGAAAAACCTCCAGTACATGAAATCAGGTGTCAACGACATCATCGA
CCGTACAACATTACTTCGATTGGCTGAAGTGTTAGAACGGGAGAGGAGAGAGCTCGTATATAGGAAAGAGAAGAATACAA
CGGAAACTTTTTTATTCCAATCCTTAAAGGAAATCCAATTACAAAAATTTGCCTTGGACCAAGCCAATATCGTATCAATC
ACCGATGCCAATGGAATCATCACCTATGTGAATGAAGCATTTGCGAATGCCACAGGTTTTCCTGTCACAGAGTTACTCGG
TCAAAACCACCGCATCCTTAAATGCCAAAATAAAACCAAAGAGGAATGGGAAAAAATTTGGGAATCCATCCACAAAGGTA
AGGTTTGGCGTGGAGAAATACTCAACACGAAAAAAGATGGATCAAGCTTCTGGGTCGACACAACGATAGTTCCTTTTATT
GGAACCGATGGATCTGTATTCCAATACATCGCCATCCATCACGACATCACAGATCGAAAATTAGCAGAAGAACAACTAAC
ACATGATGCATTTTATGATAACCTCACAGGTTTACCCAACCGAGCTTTGTATCTGGCAAGAATTGAACAAAAAATTTTCT
CATACAATATCAAAAACGATGGGTATCCAATTCTTTTTTGTATCAATATCGATAACTTTAAAAGGATCAATCATTCACTC
GGAAACGAGGCAGGTGATAAGATCCTCATCATATTCTCCCAAAGATTGAAACAATTTTCTGATAAAGAAGCAGTGATCAC
TAGACTGGGAGCAGATAATTTCTCCATTCTCCTCAATCACTTACTCTCCATTGAAGAAGCTGTCGATTATGCATACCGTT
TGCTTGAATACATTGGTGATCCAATTCCAATCGGTGGTTATGAAATTTATTTAACGGCTTCTTGTGGGATCTCAGGTTTT
GGACTTGGTGGAAAGGAAGCTGATGTGTTACTTAGAAATGCAGAGATTGCCATGTTCCATGCAAAATCGCAGAAAGTAGG
GCTTGTCTCTGTGTTTAACCAGGCAATGCAGGAAAGAATCCATTTCCAACTGGAAATCCAAAACGATCTTAAAAAAGCTC
TCAACCAAAATGAAATTTCAGTCTTTTACCAACCAATTTTAGATTTAAAGACCAATAAAATTGGACACTGGGAAGCGCTC
GTTAGGTGGCGCCATCCCCAACGTGGAATGGTGTCTCCGGCAGAATTCATCCCCCTTGCAGAAGATTCAGGACTCATTGT
TCCTATTACACGTTTTGTTTTAGAACAAAGTGCAAATGTGATCGAAGAAGTACAGATTAAAAATGGAAAACCGATATCAA
TTGCCGTCAATTTAAGCCCTCAGGTGTTTTTTGATCAAAACATCTTCCATTGGATTGTAGATTTACACAAACAAAGAAAT
ATTCCCTACACATCCTTGCAGGTAGAAATCACCGAAAGTTTGGCCATGAAAAATTTATCAGAGACTGTACCGATCCTTTC
GAATTTGATTGATATTGGTGTCAAAGTTGCTTTGGATGATTTTGGAACCGGCTTTTCTTCCTTATCGTATTTGGAAAAAC
TTCCACTTTCGATTTTAAAAATTGATAAGTCTTTTTTAAATAATGTTCATGTTGGGTCCAAGGAAAGTTTTTTACTCATT
TCCATTATCAATATGGCACACGACCTAGGTTATTCTGTGGTCGCGGAAGGAGTAGAGGAATTAGAACAGTTGGAACTTCT
TAAGTCATACCAATGTGATGAAATCCAAGGGTATTGGTTATCAAAACCAATCCCTTTTCCTGAAATCATTCCATTTTTAG
ATCAGTTTTATCAGAAGGAGAATCAATGA

Upstream 100 bases:

>100_bases
ATTCGACGAGAATTCAAAGAAATTTCGAATCATTTTTAGGTTGAGATTTTTAGATTTTTCCCCATCCTAAACCGAGAGAA
CCGCCACTTCGGCAAACAAA

Downstream 100 bases:

>100_bases
AAGGAATCAAAATTCTTTTGTTCATAGTATTGTCATTTGTTCAGTGTAATACTTCCCCAACCGGAAGGCGTCAAATTACC
TTAGTTGGTGATGAAGAAAT

Product: putative two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MGSPISVLILENDSSSVFDIVREMKANGLSPLYKVVESFGSFESTVLEEDWDAILCSTRKPFHLEISLYLKFLNEKKIDI
PVILISDQEDFQKNLQYMKSGVNDIIDRTTLLRLAEVLERERRELVYRKEKNTTETFLFQSLKEIQLQKFALDQANIVSI
TDANGIITYVNEAFANATGFPVTELLGQNHRILKCQNKTKEEWEKIWESIHKGKVWRGEILNTKKDGSSFWVDTTIVPFI
GTDGSVFQYIAIHHDITDRKLAEEQLTHDAFYDNLTGLPNRALYLARIEQKIFSYNIKNDGYPILFCINIDNFKRINHSL
GNEAGDKILIIFSQRLKQFSDKEAVITRLGADNFSILLNHLLSIEEAVDYAYRLLEYIGDPIPIGGYEIYLTASCGISGF
GLGGKEADVLLRNAEIAMFHAKSQKVGLVSVFNQAMQERIHFQLEIQNDLKKALNQNEISVFYQPILDLKTNKIGHWEAL
VRWRHPQRGMVSPAEFIPLAEDSGLIVPITRFVLEQSANVIEEVQIKNGKPISIAVNLSPQVFFDQNIFHWIVDLHKQRN
IPYTSLQVEITESLAMKNLSETVPILSNLIDIGVKVALDDFGTGFSSLSYLEKLPLSILKIDKSFLNNVHVGSKESFLLI
SIINMAHDLGYSVVAEGVEELEQLELLKSYQCDEIQGYWLSKPIPFPEIIPFLDQFYQKENQ

Sequences:

>Translated_702_residues
MGSPISVLILENDSSSVFDIVREMKANGLSPLYKVVESFGSFESTVLEEDWDAILCSTRKPFHLEISLYLKFLNEKKIDI
PVILISDQEDFQKNLQYMKSGVNDIIDRTTLLRLAEVLERERRELVYRKEKNTTETFLFQSLKEIQLQKFALDQANIVSI
TDANGIITYVNEAFANATGFPVTELLGQNHRILKCQNKTKEEWEKIWESIHKGKVWRGEILNTKKDGSSFWVDTTIVPFI
GTDGSVFQYIAIHHDITDRKLAEEQLTHDAFYDNLTGLPNRALYLARIEQKIFSYNIKNDGYPILFCINIDNFKRINHSL
GNEAGDKILIIFSQRLKQFSDKEAVITRLGADNFSILLNHLLSIEEAVDYAYRLLEYIGDPIPIGGYEIYLTASCGISGF
GLGGKEADVLLRNAEIAMFHAKSQKVGLVSVFNQAMQERIHFQLEIQNDLKKALNQNEISVFYQPILDLKTNKIGHWEAL
VRWRHPQRGMVSPAEFIPLAEDSGLIVPITRFVLEQSANVIEEVQIKNGKPISIAVNLSPQVFFDQNIFHWIVDLHKQRN
IPYTSLQVEITESLAMKNLSETVPILSNLIDIGVKVALDDFGTGFSSLSYLEKLPLSILKIDKSFLNNVHVGSKESFLLI
SIINMAHDLGYSVVAEGVEELEQLELLKSYQCDEIQGYWLSKPIPFPEIIPFLDQFYQKENQ
>Mature_701_residues
GSPISVLILENDSSSVFDIVREMKANGLSPLYKVVESFGSFESTVLEEDWDAILCSTRKPFHLEISLYLKFLNEKKIDIP
VILISDQEDFQKNLQYMKSGVNDIIDRTTLLRLAEVLERERRELVYRKEKNTTETFLFQSLKEIQLQKFALDQANIVSIT
DANGIITYVNEAFANATGFPVTELLGQNHRILKCQNKTKEEWEKIWESIHKGKVWRGEILNTKKDGSSFWVDTTIVPFIG
TDGSVFQYIAIHHDITDRKLAEEQLTHDAFYDNLTGLPNRALYLARIEQKIFSYNIKNDGYPILFCINIDNFKRINHSLG
NEAGDKILIIFSQRLKQFSDKEAVITRLGADNFSILLNHLLSIEEAVDYAYRLLEYIGDPIPIGGYEIYLTASCGISGFG
LGGKEADVLLRNAEIAMFHAKSQKVGLVSVFNQAMQERIHFQLEIQNDLKKALNQNEISVFYQPILDLKTNKIGHWEALV
RWRHPQRGMVSPAEFIPLAEDSGLIVPITRFVLEQSANVIEEVQIKNGKPISIAVNLSPQVFFDQNIFHWIVDLHKQRNI
PYTSLQVEITESLAMKNLSETVPILSNLIDIGVKVALDDFGTGFSSLSYLEKLPLSILKIDKSFLNNVHVGSKESFLLIS
IINMAHDLGYSVVAEGVEELEQLELLKSYQCDEIQGYWLSKPIPFPEIIPFLDQFYQKENQ

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=33.6405529953917, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI87081921, Length=423, Percent_Identity=34.0425531914894, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788502, Length=360, Percent_Identity=28.0555555555556, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081845, Length=241, Percent_Identity=34.8547717842324, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=34.7639484978541, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI226510982, Length=426, Percent_Identity=25.1173708920188, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1790496, Length=259, Percent_Identity=33.2046332046332, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=33.984375, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081743, Length=251, Percent_Identity=33.0677290836653, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787055, Length=455, Percent_Identity=24.8351648351648, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=31.0756972111554, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI87082096, Length=246, Percent_Identity=29.2682926829268, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1788381, Length=319, Percent_Identity=25.705329153605, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1789453, Length=110, Percent_Identity=30, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87081881, Length=251, Percent_Identity=28.6852589641434, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081977, Length=187, Percent_Identity=31.5508021390374, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=29.4478527607362, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 80070; Mature: 79939

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSPISVLILENDSSSVFDIVREMKANGLSPLYKVVESFGSFESTVLEEDWDAILCSTRK
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCCCEEECCCC
PFHLEISLYLKFLNEKKIDIPVILISDQEDFQKNLQYMKSGVNDIIDRTTLLRLAEVLER
CEEEEHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRELVYRKEKNTTETFLFQSLKEIQLQKFALDQANIVSITDANGIITYVNEAFANATGF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHCCCCCC
PVTELLGQNHRILKCQNKTKEEWEKIWESIHKGKVWRGEILNTKKDGSSFWVDTTIVPFI
CHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEEEEEE
GTDGSVFQYIAIHHDITDRKLAEEQLTHDAFYDNLTGLPNRALYLARIEQKIFSYNIKND
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCC
GYPILFCINIDNFKRINHSLGNEAGDKILIIFSQRLKQFSDKEAVITRLGADNFSILLNH
CCEEEEEEECCHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCHHHHHHHCCCCHHHHHHHH
LLSIEEAVDYAYRLLEYIGDPIPIGGYEIYLTASCGISGFGLGGKEADVLLRNAEIAMFH
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHEEEECCEEEEEE
AKSQKVGLVSVFNQAMQERIHFQLEIQNDLKKALNQNEISVFYQPILDLKTNKIGHWEAL
CCCCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
VRWRHPQRGMVSPAEFIPLAEDSGLIVPITRFVLEQSANVIEEVQIKNGKPISIAVNLSP
HHCCCCCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
QVFFDQNIFHWIVDLHKQRNIPYTSLQVEITESLAMKNLSETVPILSNLIDIGVKVALDD
CEEECCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
FGTGFSSLSYLEKLPLSILKIDKSFLNNVHVGSKESFLLISIINMAHDLGYSVVAEGVEE
CCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHH
LEQLELLKSYQCDEIQGYWLSKPIPFPEIIPFLDQFYQKENQ
HHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSPISVLILENDSSSVFDIVREMKANGLSPLYKVVESFGSFESTVLEEDWDAILCSTRK
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCCCEEECCCC
PFHLEISLYLKFLNEKKIDIPVILISDQEDFQKNLQYMKSGVNDIIDRTTLLRLAEVLER
CEEEEHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRELVYRKEKNTTETFLFQSLKEIQLQKFALDQANIVSITDANGIITYVNEAFANATGF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHCCCCCC
PVTELLGQNHRILKCQNKTKEEWEKIWESIHKGKVWRGEILNTKKDGSSFWVDTTIVPFI
CHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEEEEEE
GTDGSVFQYIAIHHDITDRKLAEEQLTHDAFYDNLTGLPNRALYLARIEQKIFSYNIKND
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCC
GYPILFCINIDNFKRINHSLGNEAGDKILIIFSQRLKQFSDKEAVITRLGADNFSILLNH
CCEEEEEEECCHHHHHHHHHCCCCCCEEEEEEHHHHHHCCCHHHHHHHCCCCHHHHHHHH
LLSIEEAVDYAYRLLEYIGDPIPIGGYEIYLTASCGISGFGLGGKEADVLLRNAEIAMFH
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHEEEECCEEEEEE
AKSQKVGLVSVFNQAMQERIHFQLEIQNDLKKALNQNEISVFYQPILDLKTNKIGHWEAL
CCCCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
VRWRHPQRGMVSPAEFIPLAEDSGLIVPITRFVLEQSANVIEEVQIKNGKPISIAVNLSP
HHCCCCCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
QVFFDQNIFHWIVDLHKQRNIPYTSLQVEITESLAMKNLSETVPILSNLIDIGVKVALDD
CEEECCCHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEC
FGTGFSSLSYLEKLPLSILKIDKSFLNNVHVGSKESFLLISIINMAHDLGYSVVAEGVEE
CCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHH
LEQLELLKSYQCDEIQGYWLSKPIPFPEIIPFLDQFYQKENQ
HHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]