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The map label for this gene is ntrY [H]

Identifier: 183221040

GI number: 183221040

Start: 1727727

End: 1729550

Strand: Direct

Name: ntrY [H]

Synonym: LEPBI_I1653

Alternate gene names: 183221040

Gene position: 1727727-1729550 (Clockwise)

Preceding gene: 183221039

Following gene: 183221041

Centisome position: 48.0

GC content: 35.09

Gene sequence:

>1824_bases
ATGCCAAATAAATTCCTTCGATTTTTCCCAAACATCTCTGATGAAAATCGTTATTATTTAAGAGATATCTTTATCTTTTT
TTTGACTCTTGCTATCTCCATTGGGTTTTCAGAACTAGTATTCTTTCGGGAAGAAGAAGACATTTCGTTATATTCAAAAT
TAGATACTTATGTTTTTATTCTCATTCCATTTTTTATCTTATCCTTAATTCTAAGTTATGTTTATCGAAACCGTAGAAAT
CGAGAAACTGGGAAAATTAGAAGTTCTATTCGATACCGACTAACGCTTGCATTTTTATTCGTGGCACTTGTACCTTCCTT
ACCAATTTTCATTTTGTCCTCTAACTTGACAGGAAGGCTCATTGAAGGATTCTATCAAGTTGACATTTCGAATGCATTAC
GTTCTGCCAATTTTTTTGTGAATCAAATTGAAAAAGAAAAGGAAGTTTCCTTTTTGGAAATGATCTCGCGTTTTCGTTCT
ATTTTGCTTCGCGAAAAACCTGATAGTTTTTCCATTTTTCAAAAGGGTATTAAAAACGGATTTTTTGAAAAAAATGAATT
TTATTTAGGATATATTGAAAAAGAAAAAGTTCAATTTGAATCAAAGGGTTTGTACCGGCATTTTCATTCCTTGGAATTTG
ACGAATCCAAAGAAAAAGGTATTTATCTAAGTCGATACTATGATGCCGATAAGGCATATTTAGTTGCTAAGTTTAGTTTG
GATGGTAATGCAAAAGTTTTGATTGCCCAAAGGATCCATAGGGGAATGGAATCCGATGTATTGAATATCGTCAATGCAAC
ATCCACTTATGAGAAAGTGAGTTTATGGAAGGAAAAAATTCCCTTTAGTGTTCGTATCACTATTGCTAGTTTTTCGTTTA
GTATGTTTCTCATTGCCATTCTGTTCTCATTCCTATTTGCCAGGCGAATTTCTAAACCTATCATCAATTTGGCGAACGCA
ACCAAAAAGGTATCTCTTGGAGAATCTGATATCCGTTTGGAAAAAACGGAAGAAGGAGAAATGGGAATTTTGATTGATAG
TTTCAATCAAATGGTGAGTGACTTAAAAGCAAAATCTGATGAACTGATGCACACGCAAAGAATTGCTGCTTGGAAAGAAG
TGGCACAACGAATGGCACATGAAATCAAAAATCCACTGACTCCCATTCAATTATCTGCTCAAAGGATACAAAGGAAATTT
CAGAATCCAAAAAAAGAAAATTTGGAATCTGTGATTTTTGACGCAACGGAAACGATCATTGGGCAAGTGCGTGTTCTGGA
ACATTTGGTAAAGGAATTTAGTGAATTTGCTCGAATGCCGGTACCTGTTCTCATCAACCAACATATCAATCCCATTCTAG
AAGAAGCGGTTGCACTCTTTCGAGATACATCTGACATAGAATTTGAATTGAAACTTGCCGAAGATCTTCCTGAAGTATTT
CTCGATAAACGATTGTTCCTTGGTGTTGTGAATAATCTCATTAAAAATGCGGTAGAAGCCATTTTATCGCAGGAAAATTC
GAAAGAAGAAATGGATTTTCTTGGTTCGAGAAGAAAAAAAATCCGAGTGATGTCGAAATTACAAAAAAAAGCCCTACGTA
GGAGTATTGTTCTTGAGATCGACGATTCAGGCCCTGGTTTAAAAGAGGAATGGCGGGAAAAAATTTTTGAACCCTATTTT
TCAACAAAAGAGAAACATGGATCAGGGATTGGGCTTGCAATTGTCCAAAAAACGATCATTGACCATCATGGGCATATTTC
CGTTGAGAACTCAAAGTTAGGTGGCTGTAAGTTTCGTATTGAACTTCCTTTGGATCTTTCATAA

Upstream 100 bases:

>100_bases
CTCGGTCCGGGTACAGTGTTTTCCGTGAAAGCAGAGGGAAAAATGGAAGAGGAGGCACTACAAGCGTTAGAAACTCTCGT
GGTTCAGAATTTTGAAACCA

Downstream 100 bases:

>100_bases
TGCAAAAATTAATCTATATTTTAGACGATGAAAAAGAAATCCGAAAAACGTTACGAGTGATTTTGGAAGATGAGGAATAT
TCTGTCGAAGATTTTTCGAG

Product: histidine kinase sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MPNKFLRFFPNISDENRYYLRDIFIFFLTLAISIGFSELVFFREEEDISLYSKLDTYVFILIPFFILSLILSYVYRNRRN
RETGKIRSSIRYRLTLAFLFVALVPSLPIFILSSNLTGRLIEGFYQVDISNALRSANFFVNQIEKEKEVSFLEMISRFRS
ILLREKPDSFSIFQKGIKNGFFEKNEFYLGYIEKEKVQFESKGLYRHFHSLEFDESKEKGIYLSRYYDADKAYLVAKFSL
DGNAKVLIAQRIHRGMESDVLNIVNATSTYEKVSLWKEKIPFSVRITIASFSFSMFLIAILFSFLFARRISKPIINLANA
TKKVSLGESDIRLEKTEEGEMGILIDSFNQMVSDLKAKSDELMHTQRIAAWKEVAQRMAHEIKNPLTPIQLSAQRIQRKF
QNPKKENLESVIFDATETIIGQVRVLEHLVKEFSEFARMPVPVLINQHINPILEEAVALFRDTSDIEFELKLAEDLPEVF
LDKRLFLGVVNNLIKNAVEAILSQENSKEEMDFLGSRRKKIRVMSKLQKKALRRSIVLEIDDSGPGLKEEWREKIFEPYF
STKEKHGSGIGLAIVQKTIIDHHGHISVENSKLGGCKFRIELPLDLS

Sequences:

>Translated_607_residues
MPNKFLRFFPNISDENRYYLRDIFIFFLTLAISIGFSELVFFREEEDISLYSKLDTYVFILIPFFILSLILSYVYRNRRN
RETGKIRSSIRYRLTLAFLFVALVPSLPIFILSSNLTGRLIEGFYQVDISNALRSANFFVNQIEKEKEVSFLEMISRFRS
ILLREKPDSFSIFQKGIKNGFFEKNEFYLGYIEKEKVQFESKGLYRHFHSLEFDESKEKGIYLSRYYDADKAYLVAKFSL
DGNAKVLIAQRIHRGMESDVLNIVNATSTYEKVSLWKEKIPFSVRITIASFSFSMFLIAILFSFLFARRISKPIINLANA
TKKVSLGESDIRLEKTEEGEMGILIDSFNQMVSDLKAKSDELMHTQRIAAWKEVAQRMAHEIKNPLTPIQLSAQRIQRKF
QNPKKENLESVIFDATETIIGQVRVLEHLVKEFSEFARMPVPVLINQHINPILEEAVALFRDTSDIEFELKLAEDLPEVF
LDKRLFLGVVNNLIKNAVEAILSQENSKEEMDFLGSRRKKIRVMSKLQKKALRRSIVLEIDDSGPGLKEEWREKIFEPYF
STKEKHGSGIGLAIVQKTIIDHHGHISVENSKLGGCKFRIELPLDLS
>Mature_606_residues
PNKFLRFFPNISDENRYYLRDIFIFFLTLAISIGFSELVFFREEEDISLYSKLDTYVFILIPFFILSLILSYVYRNRRNR
ETGKIRSSIRYRLTLAFLFVALVPSLPIFILSSNLTGRLIEGFYQVDISNALRSANFFVNQIEKEKEVSFLEMISRFRSI
LLREKPDSFSIFQKGIKNGFFEKNEFYLGYIEKEKVQFESKGLYRHFHSLEFDESKEKGIYLSRYYDADKAYLVAKFSLD
GNAKVLIAQRIHRGMESDVLNIVNATSTYEKVSLWKEKIPFSVRITIASFSFSMFLIAILFSFLFARRISKPIINLANAT
KKVSLGESDIRLEKTEEGEMGILIDSFNQMVSDLKAKSDELMHTQRIAAWKEVAQRMAHEIKNPLTPIQLSAQRIQRKFQ
NPKKENLESVIFDATETIIGQVRVLEHLVKEFSEFARMPVPVLINQHINPILEEAVALFRDTSDIEFELKLAEDLPEVFL
DKRLFLGVVNNLIKNAVEAILSQENSKEEMDFLGSRRKKIRVMSKLQKKALRRSIVLEIDDSGPGLKEEWREKIFEPYFS
TKEKHGSGIGLAIVQKTIIDHHGHISVENSKLGGCKFRIELPLDLS

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=290, Percent_Identity=26.551724137931, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=309, Percent_Identity=26.8608414239482, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=309, Percent_Identity=27.5080906148867, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787894, Length=318, Percent_Identity=25.1572327044025, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790300, Length=267, Percent_Identity=25.0936329588015, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=26.6932270916335, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=356, Percent_Identity=24.1573033707865, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70454; Mature: 70322

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNKFLRFFPNISDENRYYLRDIFIFFLTLAISIGFSELVFFREEEDISLYSKLDTYVFI
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHEEECCCCHHHHHHHHHHHHH
LIPFFILSLILSYVYRNRRNRETGKIRSSIRYRLTLAFLFVALVPSLPIFILSSNLTGRL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHH
IEGFYQVDISNALRSANFFVNQIEKEKEVSFLEMISRFRSILLREKPDSFSIFQKGIKNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
FFEKNEFYLGYIEKEKVQFESKGLYRHFHSLEFDESKEKGIYLSRYYDADKAYLVAKFSL
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEEEC
DGNAKVLIAQRIHRGMESDVLNIVNATSTYEKVSLWKEKIPFSVRITIASFSFSMFLIAI
CCCCEEEEHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHH
LFSFLFARRISKPIINLANATKKVSLGESDIRLEKTEEGEMGILIDSFNQMVSDLKAKSD
HHHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHH
ELMHTQRIAAWKEVAQRMAHEIKNPLTPIQLSAQRIQRKFQNPKKENLESVIFDATETII
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GQVRVLEHLVKEFSEFARMPVPVLINQHINPILEEAVALFRDTSDIEFELKLAEDLPEVF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
LDKRLFLGVVNNLIKNAVEAILSQENSKEEMDFLGSRRKKIRVMSKLQKKALRRSIVLEI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
DDSGPGLKEEWREKIFEPYFSTKEKHGSGIGLAIVQKTIIDHHGHISVENSKLGGCKFRI
CCCCCCHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCEEEEE
ELPLDLS
ECCCCCC
>Mature Secondary Structure 
PNKFLRFFPNISDENRYYLRDIFIFFLTLAISIGFSELVFFREEEDISLYSKLDTYVFI
CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHEEECCCCHHHHHHHHHHHHH
LIPFFILSLILSYVYRNRRNRETGKIRSSIRYRLTLAFLFVALVPSLPIFILSSNLTGRL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHH
IEGFYQVDISNALRSANFFVNQIEKEKEVSFLEMISRFRSILLREKPDSFSIFQKGIKNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
FFEKNEFYLGYIEKEKVQFESKGLYRHFHSLEFDESKEKGIYLSRYYDADKAYLVAKFSL
CCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEEEC
DGNAKVLIAQRIHRGMESDVLNIVNATSTYEKVSLWKEKIPFSVRITIASFSFSMFLIAI
CCCCEEEEHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEEHHHHHHHHHHH
LFSFLFARRISKPIINLANATKKVSLGESDIRLEKTEEGEMGILIDSFNQMVSDLKAKSD
HHHHHHHHHHHHHHHHHHCCHHEEECCCCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHH
ELMHTQRIAAWKEVAQRMAHEIKNPLTPIQLSAQRIQRKFQNPKKENLESVIFDATETII
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GQVRVLEHLVKEFSEFARMPVPVLINQHINPILEEAVALFRDTSDIEFELKLAEDLPEVF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
LDKRLFLGVVNNLIKNAVEAILSQENSKEEMDFLGSRRKKIRVMSKLQKKALRRSIVLEI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
DDSGPGLKEEWREKIFEPYFSTKEKHGSGIGLAIVQKTIIDHHGHISVENSKLGGCKFRI
CCCCCCHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCEEEEE
ELPLDLS
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]