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The map label for this gene is cysQ [H]

Identifier: 183221023

GI number: 183221023

Start: 1712028

End: 1712897

Strand: Direct

Name: cysQ [H]

Synonym: LEPBI_I1636

Alternate gene names: 183221023

Gene position: 1712028-1712897 (Clockwise)

Preceding gene: 183221022

Following gene: 183221024

Centisome position: 47.56

GC content: 36.78

Gene sequence:

>870_bases
ATGGAAGAACAAGATTTTCAGGAAGTATGGCGATGGGTCCTTTCAGTAGGAGATTCCATCTTAAACATTTACAAAACTGA
TTTTTTAATCCGTGATAAAGGTGGCAATGATCCTGTTACGGAAGCTGATTTGTTTGCGAGTGAGTTCTTATTTGAAAAAA
TTTCGAATCGATTTCCTGGACATGGATTTTTATCAGAAGAAAAATTGGATTCAAGTTTTCGTTTGGATAAAGAATGGGTT
TGGATTTTAGACCCCATTGATGGCACAAGGGAATTCGTCAAAAAAAATGATCAATTTGCATTGAGTTTGGGTTTAGTTCG
GAACGGAGAGGCGATTTGGGGGATTATTTTTAACCCTGCAACCGGTGAGTTTTTTTCTAAAGGGAAACATAGTTTTTTTG
CCAAACTGCAAGCACCATTCGCAACCGACGAAAACTTTCGAACCCTAGTTGTCGAAAGTAGTTCCGTTTTACATCCGTTA
GAAGAAGAAAAAGAACTAAAACAAAAACCGGTATTACTTGTTTCGTTTTCGGAAATGAAAGAAGGGTTATTTAGTGATCC
TTTTTGGAAGGAAGATTTTGAAATTCGATCCATGGGTAGCATTGCTTACAAATTAGGACTTTTATCTGCAGGCTTCATTG
ATCTAATCGTTTCGTTAAAACCTAAAAATGAATGGGATATTTGTGGTGGGATCGCTCTACTCGATGAGGATCATTTTACT
TTTTTTCCGTTAAAAGATAAATCGTATTCCTTTAACCAAAAAACCACACTATCCTTTGGACTGGTCGCTGGGAAAAAAAA
GGCAGTGGAATACCTTTTCTCTAAAATTGATTTGCACCAACTATCGCTTAAGGTAAAGGAACGATGGTAA

Upstream 100 bases:

>100_bases
TCAGAAGAAATTGTTTTGGAAAAACCAGAAGGTTTGGATTTAGGCTCAAACGCACATAAAGAAGAAAAAAAGAATTAAGA
ATTCCTTATTAAAGGACGGA

Downstream 100 bases:

>100_bases
AAACATATAAAATTGGTGTGGATGCCAGGCCTCTTTCCACCCGAGTATCTGGAGTTGGTCGTCTCATTGCAGAGACATTA
AAAGCATTCCCGAACAAAGA

Product: PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MEEQDFQEVWRWVLSVGDSILNIYKTDFLIRDKGGNDPVTEADLFASEFLFEKISNRFPGHGFLSEEKLDSSFRLDKEWV
WILDPIDGTREFVKKNDQFALSLGLVRNGEAIWGIIFNPATGEFFSKGKHSFFAKLQAPFATDENFRTLVVESSSVLHPL
EEEKELKQKPVLLVSFSEMKEGLFSDPFWKEDFEIRSMGSIAYKLGLLSAGFIDLIVSLKPKNEWDICGGIALLDEDHFT
FFPLKDKSYSFNQKTTLSFGLVAGKKKAVEYLFSKIDLHQLSLKVKERW

Sequences:

>Translated_289_residues
MEEQDFQEVWRWVLSVGDSILNIYKTDFLIRDKGGNDPVTEADLFASEFLFEKISNRFPGHGFLSEEKLDSSFRLDKEWV
WILDPIDGTREFVKKNDQFALSLGLVRNGEAIWGIIFNPATGEFFSKGKHSFFAKLQAPFATDENFRTLVVESSSVLHPL
EEEKELKQKPVLLVSFSEMKEGLFSDPFWKEDFEIRSMGSIAYKLGLLSAGFIDLIVSLKPKNEWDICGGIALLDEDHFT
FFPLKDKSYSFNQKTTLSFGLVAGKKKAVEYLFSKIDLHQLSLKVKERW
>Mature_289_residues
MEEQDFQEVWRWVLSVGDSILNIYKTDFLIRDKGGNDPVTEADLFASEFLFEKISNRFPGHGFLSEEKLDSSFRLDKEWV
WILDPIDGTREFVKKNDQFALSLGLVRNGEAIWGIIFNPATGEFFSKGKHSFFAKLQAPFATDENFRTLVVESSSVLHPL
EEEKELKQKPVLLVSFSEMKEGLFSDPFWKEDFEIRSMGSIAYKLGLLSAGFIDLIVSLKPKNEWDICGGIALLDEDHFT
FFPLKDKSYSFNQKTTLSFGLVAGKKKAVEYLFSKIDLHQLSLKVKERW

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=206, Percent_Identity=29.6116504854369, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI5031789, Length=206, Percent_Identity=29.6116504854369, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790659, Length=128, Percent_Identity=28.125, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788882, Length=274, Percent_Identity=22.2627737226277, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=207, Percent_Identity=29.951690821256, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193202570, Length=103, Percent_Identity=37.8640776699029, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357303, Length=210, Percent_Identity=27.1428571428571, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357957, Length=94, Percent_Identity=38.2978723404255, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24664926, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24664918, Length=92, Percent_Identity=36.9565217391304, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357329, Length=220, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 33223; Mature: 33223

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEQDFQEVWRWVLSVGDSILNIYKTDFLIRDKGGNDPVTEADLFASEFLFEKISNRFPG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
HGFLSEEKLDSSFRLDKEWVWILDPIDGTREFVKKNDQFALSLGLVRNGEAIWGIIFNPA
CCCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEEEEECCCEEEEEEECCC
TGEFFSKGKHSFFAKLQAPFATDENFRTLVVESSSVLHPLEEEKELKQKPVLLVSFSEMK
CCHHHHCCCHHEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCEEEEEHHHHH
EGLFSDPFWKEDFEIRSMGSIAYKLGLLSAGFIDLIVSLKPKNEWDICGGIALLDEDHFT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCEEEEECCCEE
FFPLKDKSYSFNQKTTLSFGLVAGKKKAVEYLFSKIDLHQLSLKVKERW
EEEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCHHHEEEEEECCC
>Mature Secondary Structure
MEEQDFQEVWRWVLSVGDSILNIYKTDFLIRDKGGNDPVTEADLFASEFLFEKISNRFPG
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
HGFLSEEKLDSSFRLDKEWVWILDPIDGTREFVKKNDQFALSLGLVRNGEAIWGIIFNPA
CCCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEEEEECCCEEEEEEECCC
TGEFFSKGKHSFFAKLQAPFATDENFRTLVVESSSVLHPLEEEKELKQKPVLLVSFSEMK
CCHHHHCCCHHEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCEEEEEHHHHH
EGLFSDPFWKEDFEIRSMGSIAYKLGLLSAGFIDLIVSLKPKNEWDICGGIALLDEDHFT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCEEEEECCCEE
FFPLKDKSYSFNQKTTLSFGLVAGKKKAVEYLFSKIDLHQLSLKVKERW
EEEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]