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The map label for this gene is gmhA

Identifier: 183221008

GI number: 183221008

Start: 1694726

End: 1695313

Strand: Direct

Name: gmhA

Synonym: LEPBI_I1621

Alternate gene names: 183221008

Gene position: 1694726-1695313 (Clockwise)

Preceding gene: 183221007

Following gene: 183221009

Centisome position: 47.08

GC content: 41.16

Gene sequence:

>588_bases
ATGGAGCATGATACATTAATCCAATCGCAAATTGAAGATTCCATTCGGGTAAAAGCACAACTTTTGCCGTCACTTTTGCC
AAATATCAAAGCCGCAGGAAAGGTACTTGTGGATTCCTTAAAGGGCGATGGAATTTTATATTTTGCAGGGAATGGTGGGT
CTAGTTGTGATGCATCTCACATTGCGGCAGAGCTTGTCATTCGATACAAATCAGGAAATGAGCGAAAGGCAATTCCTGCG
ATAGCACTGAACAGTGACCAGGCGGTTCTCACTGCTTGTGCCAATGATTATGGATATGAATTCCTTTTCCAAAGACAACT
CCAAGCTTTCGGAAAATCCAAAGATGTTTTCATCGGACTCACAACTTCAGGGAACTCCAAGAATATCATTTTAGCAGTAG
AAGAAGCCAAAAAAAATGGGATGAAGGTTGTTTTACTCCTTGGTGGAGATGGTGGAAAATTAAAAGGAAAAGCGGATGTG
GAAATCATCATTCCATCCAGTGTCACAGCAAGGATCCAAGAGTCCCATATTTTGATCGGTCATATCCTTTGTAGCATCAT
TGAAAAGGAATTGTTTGGACTCGATTGA

Upstream 100 bases:

>100_bases
CATTCCAAAACCAAATCGATTTTTGGATTCGGATCTGCTTTGAAAGAATTTGGACAGAAAATAAATCTCATACGGGAAAG
AAGAGAGAAGGAATTAGAAC

Downstream 100 bases:

>100_bases
TCGGCCGATCATCCAAATTCAAAATGCCACACTCCAAACACGAGAAGGGCATTTCATTTGGAAATCCATTGGACTTCAAG
TCAAAAAAGGTAGCATTCAT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASHIAAELVIRYKSGNERKAIPA
IALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGLTTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADV
EIIIPSSVTARIQESHILIGHILCSIIEKELFGLD

Sequences:

>Translated_195_residues
MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASHIAAELVIRYKSGNERKAIPA
IALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGLTTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADV
EIIIPSSVTARIQESHILIGHILCSIIEKELFGLD
>Mature_195_residues
MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASHIAAELVIRYKSGNERKAIPA
IALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGLTTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADV
EIIIPSSVTARIQESHILIGHILCSIIEKELFGLD

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1786416, Length=193, Percent_Identity=42.4870466321244, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=42.3280423280423, Blast_Score=137, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_LEPBA (B0SHL8)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001962657.1
- ProteinModelPortal:   B0SHL8
- SMR:   B0SHL8
- GeneID:   6388501
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_1571
- HOGENOM:   HBG671955
- OMA:   IIAHARD
- ProtClustDB:   PRK13937
- BioCyc:   LBIF355278:LBF_1571-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR020620
- InterPro:   IPR001347

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 20850; Mature: 20850

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS51464 SIS

Important sites: BINDING 64-64 BINDING 126-126 BINDING 173-173

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHEEECCCCCEEEEEECCCCCCCCHHH
IAAELVIRYKSGNERKAIPAIALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGL
HEEEEEEEECCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
TTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADVEIIIPSSVTARIQESHILIG
EECCCCCEEEEEEECCCCCCCEEEEEEECCCCEECCCCCEEEEECCCCEEEHHCCEEHHH
HILCSIIEKELFGLD
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHDTLIQSQIEDSIRVKAQLLPSLLPNIKAAGKVLVDSLKGDGILYFAGNGGSSCDASH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHEEECCCCCEEEEEECCCCCCCCHHH
IAAELVIRYKSGNERKAIPAIALNSDQAVLTACANDYGYEFLFQRQLQAFGKSKDVFIGL
HEEEEEEEECCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEE
TTSGNSKNIILAVEEAKKNGMKVVLLLGGDGGKLKGKADVEIIIPSSVTARIQESHILIG
EECCCCCEEEEEEECCCCCCCEEEEEEECCCCEECCCCCEEEEECCCCEEEHHCCEEHHH
HILCSIIEKELFGLD
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA