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The map label for this gene is dctB [H]

Identifier: 183220871

GI number: 183220871

Start: 1542430

End: 1544061

Strand: Direct

Name: dctB [H]

Synonym: LEPBI_I1484

Alternate gene names: 183220871

Gene position: 1542430-1544061 (Clockwise)

Preceding gene: 183220868

Following gene: 183220872

Centisome position: 42.85

GC content: 36.03

Gene sequence:

>1632_bases
ATGGTGACCTCTTCCTATTTACTCTCCCAGTTTGCCAATCAAATGAAGTCGAAAGGACTCCTCATTTTGATTTCCATTCG
GATGGTGATTGTTTGGATCGGGGTAGTCGCCTCATTTTTGAATTTTGGAAAACCTCCGTTTTTCATTGCAGTTTCGTTTA
CCATTTATTTCCTAAGCACTTCCATTTTGGGAAAACAATTCATCCAAAAATCGCATACAAGTAAAATTTCGAATCCTATC
ATCATGTTTTTTTTATGCATTGATTACTTGGTTTTGCTCCTTGGTTTTTACTTAGCCATCATGGCTCATCCCATCGGTAC
GAAATCCTTACCCATTCAAAATTCAATTTTTTTCACATTGTTTTTTTTATTCCAACTCTACATTTCCTTTTTTTTACATA
GAAGATTTTCTGCAGTGATGGGTGTTGTTGTGATCCTTGGTTATCTTGGTGGGATTTATATCGCCAAATTAAATGGTGCG
GAAATTGACTTTGGATACCAACTGGTTCCGCAAGGTCCCAATCGTGTTGTATTTGTATTAGAGTTTTTGAAATTGATCTT
ACTTGCAGCGAAAACAATTTGTATTGTCAAATTAGTTTCCTTTTTACTGGATATCTTAGATAATAATAACCAGAAGTTAT
CAGAAGAATTAAACCAGAGAGAAACCACCTTAATCCAAAATGATCGGCTGGTGACACTTGGTTCACTAGCATCAAATGTT
GCCCACGAGATCAAAAATCCACTCGCTGGCATCAAATCAATGGTTTCTTATTTACTATCGGAAGAAAAAAATTTCCTTTC
GAACAAAGATCCACTTTGGTATGAAAAAGAAAAAAGTATTCTATGGAAACATCGTACAAGAAAAGAAAAAAGAGAGGAGA
TGGATATCATTTTGCAATTGTTCCATTTTTTAGAAAGGCGAGACCTGTTTTATTTTGCAGATCGTTGTATTGAGCTCGGT
ATCAATTATAAAAGTTTCGAAGACATCCCATCACAGGATACAAAATCTTGGGAATCAATTTTTTTATGGCTCAAATACAA
GACAATGGAAAATGCTAGTATACTCATCACGAATGCCATCGATCGAACAGAAAAGGTCATTTCTACCTTCCAACAATTTT
CAAAACCATTTAGCACAAAAGAAAAGGAAAAGGTGCGGATCTCCGATGGGATTCGAGACATCCTCATTCTCTACCATCAG
TATTGGGATGAGAACAGAATCCTTATCACTGATATCGATGATCATTTAGAAACCTACGTCAATGAAGCGGCGATCAAGTT
AGTTTGGTCCCACCTAATTTTTAATGCGATCCAAGCAACCGACCCTAAAACGGGAGAGATCAAAGTAGAAGTTAAGTTGA
ATCCATCCAATCAAATTGAAATCAGAGTGATCGATAATGGAGTCGGGATTCCAGTTGACCTTCAAAAAAATATCTTCCAA
CCCTTTTATACTACGAAACAAAAAGGAGAAGGGATTGGGCTTGGCCTTTATATTTCAAATTCCATTCTTTCTGAAGAGAA
TGGTTCGATCACATTTTTTTCTGTCCCAGGCAAAACTGAGTTTATTGTTACCTTACCTATGATGGAATCAAATACACAAA
AGGAGATTCAAAATGAAAACAAATCGATTTAG

Upstream 100 bases:

>100_bases
GGTCAAGATTTTGGGATTCTCCTCCCATGTCAAACGGCTCTGCAAGAGAAATGCTTGATTTTCCCAAACTTTAGCAATGG
AATGATCATACTAAAAAATT

Downstream 100 bases:

>100_bases
ACTGATATTCATAATTTTTTCTACGTTCTTTGTATGGAATTGCCAAAAACAGACGATCGATTATGAGAAAATTGCGATCG
AAATCACAAAGGAAGCAAAA

Product: putative sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MVTSSYLLSQFANQMKSKGLLILISIRMVIVWIGVVASFLNFGKPPFFIAVSFTIYFLSTSILGKQFIQKSHTSKISNPI
IMFFLCIDYLVLLLGFYLAIMAHPIGTKSLPIQNSIFFTLFFLFQLYISFFLHRRFSAVMGVVVILGYLGGIYIAKLNGA
EIDFGYQLVPQGPNRVVFVLEFLKLILLAAKTICIVKLVSFLLDILDNNNQKLSEELNQRETTLIQNDRLVTLGSLASNV
AHEIKNPLAGIKSMVSYLLSEEKNFLSNKDPLWYEKEKSILWKHRTRKEKREEMDIILQLFHFLERRDLFYFADRCIELG
INYKSFEDIPSQDTKSWESIFLWLKYKTMENASILITNAIDRTEKVISTFQQFSKPFSTKEKEKVRISDGIRDILILYHQ
YWDENRILITDIDDHLETYVNEAAIKLVWSHLIFNAIQATDPKTGEIKVEVKLNPSNQIEIRVIDNGVGIPVDLQKNIFQ
PFYTTKQKGEGIGLGLYISNSILSEENGSITFFSVPGKTEFIVTLPMMESNTQKEIQNENKSI

Sequences:

>Translated_543_residues
MVTSSYLLSQFANQMKSKGLLILISIRMVIVWIGVVASFLNFGKPPFFIAVSFTIYFLSTSILGKQFIQKSHTSKISNPI
IMFFLCIDYLVLLLGFYLAIMAHPIGTKSLPIQNSIFFTLFFLFQLYISFFLHRRFSAVMGVVVILGYLGGIYIAKLNGA
EIDFGYQLVPQGPNRVVFVLEFLKLILLAAKTICIVKLVSFLLDILDNNNQKLSEELNQRETTLIQNDRLVTLGSLASNV
AHEIKNPLAGIKSMVSYLLSEEKNFLSNKDPLWYEKEKSILWKHRTRKEKREEMDIILQLFHFLERRDLFYFADRCIELG
INYKSFEDIPSQDTKSWESIFLWLKYKTMENASILITNAIDRTEKVISTFQQFSKPFSTKEKEKVRISDGIRDILILYHQ
YWDENRILITDIDDHLETYVNEAAIKLVWSHLIFNAIQATDPKTGEIKVEVKLNPSNQIEIRVIDNGVGIPVDLQKNIFQ
PFYTTKQKGEGIGLGLYISNSILSEENGSITFFSVPGKTEFIVTLPMMESNTQKEIQNENKSI
>Mature_543_residues
MVTSSYLLSQFANQMKSKGLLILISIRMVIVWIGVVASFLNFGKPPFFIAVSFTIYFLSTSILGKQFIQKSHTSKISNPI
IMFFLCIDYLVLLLGFYLAIMAHPIGTKSLPIQNSIFFTLFFLFQLYISFFLHRRFSAVMGVVVILGYLGGIYIAKLNGA
EIDFGYQLVPQGPNRVVFVLEFLKLILLAAKTICIVKLVSFLLDILDNNNQKLSEELNQRETTLIQNDRLVTLGSLASNV
AHEIKNPLAGIKSMVSYLLSEEKNFLSNKDPLWYEKEKSILWKHRTRKEKREEMDIILQLFHFLERRDLFYFADRCIELG
INYKSFEDIPSQDTKSWESIFLWLKYKTMENASILITNAIDRTEKVISTFQQFSKPFSTKEKEKVRISDGIRDILILYHQ
YWDENRILITDIDDHLETYVNEAAIKLVWSHLIFNAIQATDPKTGEIKVEVKLNPSNQIEIRVIDNGVGIPVDLQKNIFQ
PFYTTKQKGEGIGLGLYISNSILSEENGSITFFSVPGKTEFIVTLPMMESNTQKEIQNENKSI

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=177, Percent_Identity=31.638418079096, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=134, Percent_Identity=35.0746268656716, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62420; Mature: 62420

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSSYLLSQFANQMKSKGLLILISIRMVIVWIGVVASFLNFGKPPFFIAVSFTIYFLST
CCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHH
SILGKQFIQKSHTSKISNPIIMFFLCIDYLVLLLGFYLAIMAHPIGTKSLPIQNSIFFTL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FFLFQLYISFFLHRRFSAVMGVVVILGYLGGIYIAKLNGAEIDFGYQLVPQGPNRVVFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEECCCEEECCCCCCCEEHHH
EFLKLILLAAKTICIVKLVSFLLDILDNNNQKLSEELNQRETTLIQNDRLVTLGSLASNV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCEEEHHHHHHHH
AHEIKNPLAGIKSMVSYLLSEEKNFLSNKDPLWYEKEKSILWKHRTRKEKREEMDIILQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
FHFLERRDLFYFADRCIELGINYKSFEDIPSQDTKSWESIFLWLKYKTMENASILITNAI
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHEEEEEEEEECCCCEEEEEEHH
DRTEKVISTFQQFSKPFSTKEKEKVRISDGIRDILILYHQYWDENRILITDIDDHLETYV
HHHHHHHHHHHHHCCCCCCCCHHHEEHHCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHH
NEAAIKLVWSHLIFNAIQATDPKTGEIKVEVKLNPSNQIEIRVIDNGVGIPVDLQKNIFQ
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCEECHHHHCC
PFYTTKQKGEGIGLGLYISNSILSEENGSITFFSVPGKTEFIVTLPMMESNTQKEIQNEN
HHHCCCCCCCCCEEEEEEECCHHCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHCC
KSI
CCC
>Mature Secondary Structure
MVTSSYLLSQFANQMKSKGLLILISIRMVIVWIGVVASFLNFGKPPFFIAVSFTIYFLST
CCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHH
SILGKQFIQKSHTSKISNPIIMFFLCIDYLVLLLGFYLAIMAHPIGTKSLPIQNSIFFTL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FFLFQLYISFFLHRRFSAVMGVVVILGYLGGIYIAKLNGAEIDFGYQLVPQGPNRVVFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEECCCEEECCCCCCCEEHHH
EFLKLILLAAKTICIVKLVSFLLDILDNNNQKLSEELNQRETTLIQNDRLVTLGSLASNV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCEEEHHHHHHHH
AHEIKNPLAGIKSMVSYLLSEEKNFLSNKDPLWYEKEKSILWKHRTRKEKREEMDIILQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
FHFLERRDLFYFADRCIELGINYKSFEDIPSQDTKSWESIFLWLKYKTMENASILITNAI
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHEEEEEEEEECCCCEEEEEEHH
DRTEKVISTFQQFSKPFSTKEKEKVRISDGIRDILILYHQYWDENRILITDIDDHLETYV
HHHHHHHHHHHHHCCCCCCCCHHHEEHHCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHH
NEAAIKLVWSHLIFNAIQATDPKTGEIKVEVKLNPSNQIEIRVIDNGVGIPVDLQKNIFQ
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCEECHHHHCC
PFYTTKQKGEGIGLGLYISNSILSEENGSITFFSVPGKTEFIVTLPMMESNTQKEIQNEN
HHHCCCCCCCCCEEEEEEECCHHCCCCCCEEEEECCCCCEEEEEECCCCCCCHHHHHHCC
KSI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]