Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 183220787

GI number: 183220787

Start: 1457697

End: 1458689

Strand: Direct

Name: trpD [H]

Synonym: LEPBI_I1398

Alternate gene names: 183220787

Gene position: 1457697-1458689 (Clockwise)

Preceding gene: 183220786

Following gene: 183220788

Centisome position: 40.5

GC content: 48.04

Gene sequence:

>993_bases
GTGGTGGCGGGACACCATTTGGTGGAAACGCACGCCGAATTCTTTTTGAATGAAGTAATGGATGGAAACGTCGCAGAACC
CGTGCTTGCTTCTTTTCTCACAGCGATGAAAATGAAAGGGGAAACGACGGACGAATTGTACGGCTTTGTCCGTGCGATGC
GTCATCATGCGATCAAACCAAAAAGCAGTTTCGGTTTTGATTTTTTGGATACCTGTGGGACGGGGGGAGATGGAAAGGGG
ACTTTGAATGTGTCCACTCTTTCGGCTCTGACTCTTGCCAGTCTTGGCCACAAGGTTGCCAAACATGGAAACCGGTCAGT
TTCTTCTCTTTCGGGAAGTTCTGACATCCTTTCGGGACTCGGATACCCTTTGGAACGAACCCATGAGGAATCTGAATCAG
AATTTGTCAAAACGGGATTTGTGTTTTTATTTGCACCGTCTTGGCACCCTGCGATGAAGTATGCGGGACCTGTTCGGGCT
GCCCTCGGTTTTCGCACTTTTTTTAATTTGATCGGACCACTTTCCAACCCATTTGCACCCACCCACCAAATTGTGGGGGT
CTATGACCGCTCCCTTTGTTTGCCAATGGCAGAGATTTTAGGGAAATTGGGTTTGAAACAAGCCATCGTTTGCCATTCAG
AAGATGGTTTGGATGAGTTTTCCATTTTTGAACCGACAAACTACGCCCATTTTGACGGAAAGACCACTAAAGAACTGCGA
TTTGATCCGAAGGGACTGAATTTGGCCCCCCGGGAACTCGATCGAAATACAGTGTTCTCTTCTTCGAAAGAAGGAGCCGA
GGCACTGTTTCGGGCCGTTCTGGAACCGAGTGAACCGACGGGTGGCACGGCGATGGTTGCTCTGAACGCGGGTGTGTCTC
TGTTTTTACTCGGTGCGGTGAAAGACATTCCTTCCGGGTATGAAATCGCCAAAGAAGCTCTACTTACGAAAAAAGTTCTC
CGATTCGTTCGTGAAACATTGAATTTAAGATAA

Upstream 100 bases:

>100_bases
GGCCTTCGTTATATCGTGACCAATTACCAACTATTAACCTTTTCCAATCTCAAAAGGATTTTTTATGACCGCTCCCACAA
TTAAAGAAATCCTCCACCAA

Downstream 100 bases:

>100_bases
GGCCTGCAAACATTGGATAAATAGCTATGCTCAATTTAGAATTTTTAACTTCACAATTCCTAATCCTTGCCCAAGAAGAG
GGTGCAAAGTCCTCTCTTCA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MVAGHHLVETHAEFFLNEVMDGNVAEPVLASFLTAMKMKGETTDELYGFVRAMRHHAIKPKSSFGFDFLDTCGTGGDGKG
TLNVSTLSALTLASLGHKVAKHGNRSVSSLSGSSDILSGLGYPLERTHEESESEFVKTGFVFLFAPSWHPAMKYAGPVRA
ALGFRTFFNLIGPLSNPFAPTHQIVGVYDRSLCLPMAEILGKLGLKQAIVCHSEDGLDEFSIFEPTNYAHFDGKTTKELR
FDPKGLNLAPRELDRNTVFSSSKEGAEALFRAVLEPSEPTGGTAMVALNAGVSLFLLGAVKDIPSGYEIAKEALLTKKVL
RFVRETLNLR

Sequences:

>Translated_330_residues
MVAGHHLVETHAEFFLNEVMDGNVAEPVLASFLTAMKMKGETTDELYGFVRAMRHHAIKPKSSFGFDFLDTCGTGGDGKG
TLNVSTLSALTLASLGHKVAKHGNRSVSSLSGSSDILSGLGYPLERTHEESESEFVKTGFVFLFAPSWHPAMKYAGPVRA
ALGFRTFFNLIGPLSNPFAPTHQIVGVYDRSLCLPMAEILGKLGLKQAIVCHSEDGLDEFSIFEPTNYAHFDGKTTKELR
FDPKGLNLAPRELDRNTVFSSSKEGAEALFRAVLEPSEPTGGTAMVALNAGVSLFLLGAVKDIPSGYEIAKEALLTKKVL
RFVRETLNLR
>Mature_330_residues
MVAGHHLVETHAEFFLNEVMDGNVAEPVLASFLTAMKMKGETTDELYGFVRAMRHHAIKPKSSFGFDFLDTCGTGGDGKG
TLNVSTLSALTLASLGHKVAKHGNRSVSSLSGSSDILSGLGYPLERTHEESESEFVKTGFVFLFAPSWHPAMKYAGPVRA
ALGFRTFFNLIGPLSNPFAPTHQIVGVYDRSLCLPMAEILGKLGLKQAIVCHSEDGLDEFSIFEPTNYAHFDGKTTKELR
FDPKGLNLAPRELDRNTVFSSSKEGAEALFRAVLEPSEPTGGTAMVALNAGVSLFLLGAVKDIPSGYEIAKEALLTKKVL
RFVRETLNLR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=242, Percent_Identity=41.3223140495868, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320561, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35798; Mature: 35798

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAGHHLVETHAEFFLNEVMDGNVAEPVLASFLTAMKMKGETTDELYGFVRAMRHHAIKP
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
KSSFGFDFLDTCGTGGDGKGTLNVSTLSALTLASLGHKVAKHGNRSVSSLSGSSDILSGL
CCCCCCHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHC
GYPLERTHEESESEFVKTGFVFLFAPSWHPAMKYAGPVRAALGFRTFFNLIGPLSNPFAP
CCCHHHHCCHHHHHHHHHCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
THQIVGVYDRSLCLPMAEILGKLGLKQAIVCHSEDGLDEFSIFEPTNYAHFDGKTTKELR
HHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCEEECCCCCEECCCCCCHHEE
FDPKGLNLAPRELDRNTVFSSSKEGAEALFRAVLEPSEPTGGTAMVALNAGVSLFLLGAV
ECCCCCCCCHHHHCCHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHH
KDIPSGYEIAKEALLTKKVLRFVRETLNLR
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAGHHLVETHAEFFLNEVMDGNVAEPVLASFLTAMKMKGETTDELYGFVRAMRHHAIKP
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
KSSFGFDFLDTCGTGGDGKGTLNVSTLSALTLASLGHKVAKHGNRSVSSLSGSSDILSGL
CCCCCCHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHC
GYPLERTHEESESEFVKTGFVFLFAPSWHPAMKYAGPVRAALGFRTFFNLIGPLSNPFAP
CCCHHHHCCHHHHHHHHHCEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
THQIVGVYDRSLCLPMAEILGKLGLKQAIVCHSEDGLDEFSIFEPTNYAHFDGKTTKELR
HHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCEEECCCCCEECCCCCCHHEE
FDPKGLNLAPRELDRNTVFSSSKEGAEALFRAVLEPSEPTGGTAMVALNAGVSLFLLGAV
ECCCCCCCCHHHHCCHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHH
KDIPSGYEIAKEALLTKKVLRFVRETLNLR
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA