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The map label for this gene is murA [H]

Identifier: 183220363

GI number: 183220363

Start: 991321

End: 992625

Strand: Reverse

Name: murA [H]

Synonym: LEPBI_I0959

Alternate gene names: 183220363

Gene position: 992625-991321 (Counterclockwise)

Preceding gene: 183220365

Following gene: 183220362

Centisome position: 27.58

GC content: 49.58

Gene sequence:

>1305_bases
GTGAGCTCTTCCTACTTCAAAATTATCGGCAAAAATCCACTCCACGGGACAATTGTTCCCCAAGGGAATAAAAACGAGGC
CCTTCCACTGCTTGGAGCTCTCCTACTTTGGGAAGGGGACGTCATTTTAGAAAACCTACCTGAAATTGCCGATGTCCTGA
AACTCATGGATGTCCTCCGCCACATTGGTGTAGAGATCACATCTCTGGATACAAAAGGATCCTACCTCTTCCAGAAAAAA
AATCCAGTGAAATCGGACTTACCTTACGAACTTTGTTCCCAACTCCGAGGGGCTGTGACTCTCGCAGGACCAATCCTTGC
CCGTACAGGCCGAGTGTTTTTGCCAAAACCTGGTGGAGACAAAATTGGACGTCGCCGGATGGACACTCACCTTCTCGCCC
TCGAAGCCCTTGGCGCCAAAATCGAAGTTTTCCCAGATGGGTACATGCTCACTGCCGACAGATTGTTCGGAAAAGACATT
TTACTCGATGAAACCTCTGTCACGGCTACAGAAAATGCAGTGATGGCCGCCGTGTTTGCAGAAGGCACCACGATCATTCG
GAATGCCGCATCCGAACCTCATGTCCAAGGCCTTTGCCGATTTTTGGAAGCCGCTGGTGCTAAAATAGATGGAATTGGGA
CAAACCGACTCACGATCACAGGAGTCACTTCCCTTTCTTCTCCAGAAGGTGGTCTCAAACACCGCATTGGTTCCGACTAT
TTAGAAGTGGGTTCCTTTATCAGCCTTGCCGCCGTGACGGGAGGGGAGATCCATATCACCGACGTAAACCCGGAAGACAT
TCGAATGATCCGAATGGTCTACTCAAGACTTGGGATCGAAGTGCGACCCACTGAAACAGGCATCCTTGTCCCATCCGACC
AAAAAATGGAAATCATCCCTGACTACCATGGTGCCACTCCCAAAATTGATGATGCACCTTGGCCAGGTTTCCCGGCCGAC
ATGACTTCCGTTGCTTTGGTCACTGCCACTCAGTGTAAAGGGACAGTCCTCATCCATGAAAAACTCTTTGAATCCAGACT
CTTCTTTGTGGATCATATCATCGCTATGGGTGCCCAAATCATCCTCTGTGACCCGCACCGTGCCATCGTGATTGGTGCCA
ATCGTTTGTATGGACAACGAGTGGCAAGTCCCGACATTCGTGCTGGGATGGCCATGATCATCGCAGCACTCTGCGCAGAA
GGCCAAAGCGAGATCCATAACATTGTTCAAATTGACAGAGGGTTTGAATCCATTGACACAAGGTTACGATCCCTTGGAGC
CCAAATCGAAAGAATTCCGAGTTAA

Upstream 100 bases:

>100_bases
ATGTAGATTGAATCAAATTTTGGAAAAATCCAAACGACCTGTGCCATAAAAATCATAAATTACTTTTCCTCATATCTCTG
TTGTGTCGAATGGAAGTAAG

Downstream 100 bases:

>100_bases
ATGAAACGAAAGGATCTATTCCGAGAAGGTTTTAAATCCGTATTCCAATTTACCTTTACCAAAGCGGAAGAAATCTCAGA
AGCCATCAAAGAAGTTTGGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSSSYFKIIGKNPLHGTIVPQGNKNEALPLLGALLLWEGDVILENLPEIADVLKLMDVLRHIGVEITSLDTKGSYLFQKK
NPVKSDLPYELCSQLRGAVTLAGPILARTGRVFLPKPGGDKIGRRRMDTHLLALEALGAKIEVFPDGYMLTADRLFGKDI
LLDETSVTATENAVMAAVFAEGTTIIRNAASEPHVQGLCRFLEAAGAKIDGIGTNRLTITGVTSLSSPEGGLKHRIGSDY
LEVGSFISLAAVTGGEIHITDVNPEDIRMIRMVYSRLGIEVRPTETGILVPSDQKMEIIPDYHGATPKIDDAPWPGFPAD
MTSVALVTATQCKGTVLIHEKLFESRLFFVDHIIAMGAQIILCDPHRAIVIGANRLYGQRVASPDIRAGMAMIIAALCAE
GQSEIHNIVQIDRGFESIDTRLRSLGAQIERIPS

Sequences:

>Translated_434_residues
MSSSYFKIIGKNPLHGTIVPQGNKNEALPLLGALLLWEGDVILENLPEIADVLKLMDVLRHIGVEITSLDTKGSYLFQKK
NPVKSDLPYELCSQLRGAVTLAGPILARTGRVFLPKPGGDKIGRRRMDTHLLALEALGAKIEVFPDGYMLTADRLFGKDI
LLDETSVTATENAVMAAVFAEGTTIIRNAASEPHVQGLCRFLEAAGAKIDGIGTNRLTITGVTSLSSPEGGLKHRIGSDY
LEVGSFISLAAVTGGEIHITDVNPEDIRMIRMVYSRLGIEVRPTETGILVPSDQKMEIIPDYHGATPKIDDAPWPGFPAD
MTSVALVTATQCKGTVLIHEKLFESRLFFVDHIIAMGAQIILCDPHRAIVIGANRLYGQRVASPDIRAGMAMIIAALCAE
GQSEIHNIVQIDRGFESIDTRLRSLGAQIERIPS
>Mature_433_residues
SSSYFKIIGKNPLHGTIVPQGNKNEALPLLGALLLWEGDVILENLPEIADVLKLMDVLRHIGVEITSLDTKGSYLFQKKN
PVKSDLPYELCSQLRGAVTLAGPILARTGRVFLPKPGGDKIGRRRMDTHLLALEALGAKIEVFPDGYMLTADRLFGKDIL
LDETSVTATENAVMAAVFAEGTTIIRNAASEPHVQGLCRFLEAAGAKIDGIGTNRLTITGVTSLSSPEGGLKHRIGSDYL
EVGSFISLAAVTGGEIHITDVNPEDIRMIRMVYSRLGIEVRPTETGILVPSDQKMEIIPDYHGATPKIDDAPWPGFPADM
TSVALVTATQCKGTVLIHEKLFESRLFFVDHIIAMGAQIILCDPHRAIVIGANRLYGQRVASPDIRAGMAMIIAALCAEG
QSEIHNIVQIDRGFESIDTRLRSLGAQIERIPS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=432, Percent_Identity=35.1851851851852, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47002; Mature: 46871

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSYFKIIGKNPLHGTIVPQGNKNEALPLLGALLLWEGDVILENLPEIADVLKLMDVLR
CCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHH
HIGVEITSLDTKGSYLFQKKNPVKSDLPYELCSQLRGAVTLAGPILARTGRVFLPKPGGD
HCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEECHHHHCCCCEEEECCCCC
KIGRRRMDTHLLALEALGAKIEVFPDGYMLTADRLFGKDILLDETSVTATENAVMAAVFA
HHHHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHCCCEEEEECCCCCCCCCCEEEEEEC
EGTTIIRNAASEPHVQGLCRFLEAAGAKIDGIGTNRLTITGVTSLSSPEGGLKHRIGSDY
CCCHHHHCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCCCHHHHCCCHH
LEVGSFISLAAVTGGEIHITDVNPEDIRMIRMVYSRLGIEVRPTETGILVPSDQKMEIIP
HHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCEEECCCCEEEECCCCCEEECC
DYHGATPKIDDAPWPGFPADMTSVALVTATQCKGTVLIHEKLFESRLFFVDHIIAMGAQI
CCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCEE
ILCDPHRAIVIGANRLYGQRVASPDIRAGMAMIIAALCAEGQSEIHNIVQIDRGFESIDT
EEECCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
RLRSLGAQIERIPS
HHHHHHHHHHCCCC
>Mature Secondary Structure 
SSSYFKIIGKNPLHGTIVPQGNKNEALPLLGALLLWEGDVILENLPEIADVLKLMDVLR
CCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHH
HIGVEITSLDTKGSYLFQKKNPVKSDLPYELCSQLRGAVTLAGPILARTGRVFLPKPGGD
HCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEECHHHHCCCCEEEECCCCC
KIGRRRMDTHLLALEALGAKIEVFPDGYMLTADRLFGKDILLDETSVTATENAVMAAVFA
HHHHHHHHHHHHHHHHCCCEEEECCCCEEEEHHHHCCCEEEEECCCCCCCCCCEEEEEEC
EGTTIIRNAASEPHVQGLCRFLEAAGAKIDGIGTNRLTITGVTSLSSPEGGLKHRIGSDY
CCCHHHHCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCCCCHHHHCCCHH
LEVGSFISLAAVTGGEIHITDVNPEDIRMIRMVYSRLGIEVRPTETGILVPSDQKMEIIP
HHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCEEECCCCEEEECCCCCEEECC
DYHGATPKIDDAPWPGFPADMTSVALVTATQCKGTVLIHEKLFESRLFFVDHIIAMGAQI
CCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCEE
ILCDPHRAIVIGANRLYGQRVASPDIRAGMAMIIAALCAEGQSEIHNIVQIDRGFESIDT
EEECCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
RLRSLGAQIERIPS
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA