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The map label for this gene is cat1 [H]

Identifier: 183220258

GI number: 183220258

Start: 867961

End: 869463

Strand: Direct

Name: cat1 [H]

Synonym: LEPBI_I0851

Alternate gene names: 183220258

Gene position: 867961-869463 (Clockwise)

Preceding gene: 183220256

Following gene: 183220259

Centisome position: 24.11

GC content: 39.12

Gene sequence:

>1503_bases
ATGACCGTATCCAACTCACTGATAGAAGAAAAATTAAAAACTGCCGAAGAAATCGCCCAATTATTACCAAATCATGTGAC
AATGGGCTGTTCAGGATTCACTCCTGCCGGATATCCAAAACTGATCCCCCAAGCCTTTGCCAATCGTATTGAAACTGAAA
AAAAATCTGGCAAAACTTTTTCTATCAATCTTTACGCTGGTGCCTCCACTGGAGAAGAGTTAGATGGTGTTCTCGCGAAA
ACGGGAGCACTTAAATTAAGAATTCCTTACCAATCCAATTCATATTTACGAAACTTAATCAACCAAGGGGAAACGGATTT
TATTGATATGCACCTTTCCCATGTCGTCAAATACATCGAACATGGAATTTTACCAAAAATTGATGTTGCCATTGTGGAAG
CAATTGATGTGACCAACGATGGAAAAATTTATTTGTCTACATCCTCTGGAATGAGTGCCACATATATCAAAAATGCAGAA
TCCGTTTATATCGAGTTAACCGACACGCATCCTCTGGAACTTAAGAACTACCATGATATTTATTTACCAAGCCATCATTC
CAAAGGTGGGCCGATTCCCATCATCAATCCACAGGATCGAATTGGGGAATCTTATGTACAAGTCCCACCTGAAAAAATAA
AAGGAATTGTTCGATCAAGTAAACCAGATGCCGCAACCGTATTTAAAACTCCTGATTCTGATTGCCAAAACATTGCAGCC
CATGTCTTAGAATTCATCCAACATGAAATCAAAATGGGAAGGATTCCAAAAGAATACCTACCTTTTCAAAATGGGGTGGG
TAACATCGCAAATGCTGTGCTTGCGAGTATGGCAAAAGATCCAAAATTCCACGCCATTCAAATGTATACTGAAGTGGTGC
AAGATTCCGTATTTGATTTGATTGATGCTGGCAAATTAGAGATTGCATCTACATCAGCTCTCACCTTTTCCGAGTTAGGT
TTGAAACGATTTCATGAGAATATATCTGCTTGGAAGTCAAAATTTGTGATCCGACCTCAAGAGATTTCGAATCATCCAGA
AGTGATCCGTCGAATGGGTCTGATTGCCATGAATACAGCGATTGAAATCGATATTTATGGAAATGTAAACTCCACTCATG
TGATGGGTACATCGATGATGAATGGAATTGGAGGATCAGGAGATTTTACACGGAATTCCCATCTTAGTATTTTTATGACA
CCTTCTCTTGCCAAGGATGGAAACATATCTGCCATTGTTCCGATGGTTTCCCATACAGATCATAATGAACATTCAACGAT
GATTTTTGTTACCGAAAATGGATTGGCAGATTTAAGAGGATGCCCACCCAAAAAACGTGCAGAACTGATCATAGAAAAAT
GTGCTCACCCAATCTACAGAGACAAACTTCGCTCTTATTATGAAACTGCACTCAAAGTTTCCAAAGGCAAACACACTCCG
CATGATTTAGAAAATGCATTGTCTTGGCATGTGAAGTTTTTAAAGACAGGAAGTATGAAGTGA

Upstream 100 bases:

>100_bases
ACCGAATAGAAATATAAGAGAAAATCCATACGTTCAGAATTTGGACTTTTTATTTTTAGGCAATCTCTTTATCTTTGGTC
AAAGAAGAGATTTTAGATTT

Downstream 100 bases:

>100_bases
TTGCTATTGTCGGATCAGGAATCACGGGACTCACTGCGGCTTGGGCCCTCAATAAATTTTGTGAAGTTTCTTTATATGAG
AAACATTCAGATGTTGGAAT

Product: putative acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTVSNSLIEEKLKTAEEIAQLLPNHVTMGCSGFTPAGYPKLIPQAFANRIETEKKSGKTFSINLYAGASTGEELDGVLAK
TGALKLRIPYQSNSYLRNLINQGETDFIDMHLSHVVKYIEHGILPKIDVAIVEAIDVTNDGKIYLSTSSGMSATYIKNAE
SVYIELTDTHPLELKNYHDIYLPSHHSKGGPIPIINPQDRIGESYVQVPPEKIKGIVRSSKPDAATVFKTPDSDCQNIAA
HVLEFIQHEIKMGRIPKEYLPFQNGVGNIANAVLASMAKDPKFHAIQMYTEVVQDSVFDLIDAGKLEIASTSALTFSELG
LKRFHENISAWKSKFVIRPQEISNHPEVIRRMGLIAMNTAIEIDIYGNVNSTHVMGTSMMNGIGGSGDFTRNSHLSIFMT
PSLAKDGNISAIVPMVSHTDHNEHSTMIFVTENGLADLRGCPPKKRAELIIEKCAHPIYRDKLRSYYETALKVSKGKHTP
HDLENALSWHVKFLKTGSMK

Sequences:

>Translated_500_residues
MTVSNSLIEEKLKTAEEIAQLLPNHVTMGCSGFTPAGYPKLIPQAFANRIETEKKSGKTFSINLYAGASTGEELDGVLAK
TGALKLRIPYQSNSYLRNLINQGETDFIDMHLSHVVKYIEHGILPKIDVAIVEAIDVTNDGKIYLSTSSGMSATYIKNAE
SVYIELTDTHPLELKNYHDIYLPSHHSKGGPIPIINPQDRIGESYVQVPPEKIKGIVRSSKPDAATVFKTPDSDCQNIAA
HVLEFIQHEIKMGRIPKEYLPFQNGVGNIANAVLASMAKDPKFHAIQMYTEVVQDSVFDLIDAGKLEIASTSALTFSELG
LKRFHENISAWKSKFVIRPQEISNHPEVIRRMGLIAMNTAIEIDIYGNVNSTHVMGTSMMNGIGGSGDFTRNSHLSIFMT
PSLAKDGNISAIVPMVSHTDHNEHSTMIFVTENGLADLRGCPPKKRAELIIEKCAHPIYRDKLRSYYETALKVSKGKHTP
HDLENALSWHVKFLKTGSMK
>Mature_499_residues
TVSNSLIEEKLKTAEEIAQLLPNHVTMGCSGFTPAGYPKLIPQAFANRIETEKKSGKTFSINLYAGASTGEELDGVLAKT
GALKLRIPYQSNSYLRNLINQGETDFIDMHLSHVVKYIEHGILPKIDVAIVEAIDVTNDGKIYLSTSSGMSATYIKNAES
VYIELTDTHPLELKNYHDIYLPSHHSKGGPIPIINPQDRIGESYVQVPPEKIKGIVRSSKPDAATVFKTPDSDCQNIAAH
VLEFIQHEIKMGRIPKEYLPFQNGVGNIANAVLASMAKDPKFHAIQMYTEVVQDSVFDLIDAGKLEIASTSALTFSELGL
KRFHENISAWKSKFVIRPQEISNHPEVIRRMGLIAMNTAIEIDIYGNVNSTHVMGTSMMNGIGGSGDFTRNSHLSIFMTP
SLAKDGNISAIVPMVSHTDHNEHSTMIFVTENGLADLRGCPPKKRAELIIEKCAHPIYRDKLRSYYETALKVSKGKHTPH
DLENALSWHVKFLKTGSMK

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=45.0617283950617, Blast_Score=454, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17538151, Length=253, Percent_Identity=29.2490118577075, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=522, Percent_Identity=38.6973180076628, Blast_Score=349, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55310; Mature: 55179

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSNSLIEEKLKTAEEIAQLLPNHVTMGCSGFTPAGYPKLIPQAFANRIETEKKSGKTF
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
SINLYAGASTGEELDGVLAKTGALKLRIPYQSNSYLRNLINQGETDFIDMHLSHVVKYIE
EEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
HGILPKIDVAIVEAIDVTNDGKIYLSTSSGMSATYIKNAESVYIELTDTHPLELKNYHDI
HCCCCCCHHEEEEEEEECCCCEEEEEECCCCCEEEEECCCEEEEEEECCCCEEECCCCEE
YLPSHHSKGGPIPIINPQDRIGESYVQVPPEKIKGIVRSSKPDAATVFKTPDSDCQNIAA
ECCCCCCCCCCEEEECCHHHHCCHHHCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
HVLEFIQHEIKMGRIPKEYLPFQNGVGNIANAVLASMAKDPKFHAIQMYTEVVQDSVFDL
HHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IDAGKLEIASTSALTFSELGLKRFHENISAWKSKFVIRPQEISNHPEVIRRMGLIAMNTA
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHCCEEECCE
IEIDIYGNVNSTHVMGTSMMNGIGGSGDFTRNSHLSIFMTPSLAKDGNISAIVPMVSHTD
EEEEEECCCCCCEEECHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEHHCCC
HNEHSTMIFVTENGLADLRGCPPKKRAELIIEKCAHPIYRDKLRSYYETALKVSKGKHTP
CCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCH
HDLENALSWHVKFLKTGSMK
HHHHHHHHHHHHEEECCCCC
>Mature Secondary Structure 
TVSNSLIEEKLKTAEEIAQLLPNHVTMGCSGFTPAGYPKLIPQAFANRIETEKKSGKTF
CCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
SINLYAGASTGEELDGVLAKTGALKLRIPYQSNSYLRNLINQGETDFIDMHLSHVVKYIE
EEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
HGILPKIDVAIVEAIDVTNDGKIYLSTSSGMSATYIKNAESVYIELTDTHPLELKNYHDI
HCCCCCCHHEEEEEEEECCCCEEEEEECCCCCEEEEECCCEEEEEEECCCCEEECCCCEE
YLPSHHSKGGPIPIINPQDRIGESYVQVPPEKIKGIVRSSKPDAATVFKTPDSDCQNIAA
ECCCCCCCCCCEEEECCHHHHCCHHHCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
HVLEFIQHEIKMGRIPKEYLPFQNGVGNIANAVLASMAKDPKFHAIQMYTEVVQDSVFDL
HHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IDAGKLEIASTSALTFSELGLKRFHENISAWKSKFVIRPQEISNHPEVIRRMGLIAMNTA
HCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCHHHHHHHCCEEECCE
IEIDIYGNVNSTHVMGTSMMNGIGGSGDFTRNSHLSIFMTPSLAKDGNISAIVPMVSHTD
EEEEEECCCCCCEEECHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEHHCCC
HNEHSTMIFVTENGLADLRGCPPKKRAELIIEKCAHPIYRDKLRSYYETALKVSKGKHTP
CCCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCH
HDLENALSWHVKFLKTGSMK
HHHHHHHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]