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The map label for this gene is bioD [H]

Identifier: 183220233

GI number: 183220233

Start: 839044

End: 839751

Strand: Direct

Name: bioD [H]

Synonym: LEPBI_I0826

Alternate gene names: 183220233

Gene position: 839044-839751 (Clockwise)

Preceding gene: 183220230

Following gene: 183220234

Centisome position: 23.31

GC content: 39.97

Gene sequence:

>708_bases
TTGATAAAACTTGCTCTTATGGGCCAAGCTTTTTATGTAACGGGGACAGGAACCGATGTCGGGAAAACCTTTTTTTCCAG
TCTGTTCATGGCAAAATATGCAAAAAAGTATGGATTTCGTTATTGGAAACCGATCCAAACAGGATCTATCAGCGCGGATG
ATACAACCTTTGTCCAAAAGACGACAAGTTTACCAGATTCTTATTTTTTAAAACCAAACTATGTTTTTAAAACACCAGCA
AGCCCTCATTACGCGGCAAAAATAGAAGGTCAAACCATTGATCCAAAATCACTTTTGTCCTCCGTCTCAAAAGAGAGAAA
AACTAATACTTTGATTGAAGGGGCAGGGGGAGTGTTTGTACCCATCACGGAAGATTATCTCACGATCCGCGCCATCCAAG
AATCCAATTTGGGTGTGGTGGTGGTAGGATCTACTGAACTAGGAACCATCAATCATACCTTAATGACATTGGAAGTGTTA
ACCTCACGTTTTATACCCGTATTTGGATTTTATTTGGTGGGCCCCGAAAACTCTCTCCAAGAAGACAATGCCACTATGAT
ACAAAGATTAGGTGGGGCTTCCTTTTTGGGATTTACCAATTTCCCTGAACAAAAATTGACATCTGATGAGTTTATCAGAT
TTGCCTCAGAACATTTTGATCCAAACCGAAATGTGATCGATGTTGTATTGAATGCAGATGAGGAATGA

Upstream 100 bases:

>100_bases
AATCTCTGTAATGGGATTGTCATCGCGTTTGAGAATGGATTTCCAAAGGGGAAGTTGCATATTGCCTCTACTATATAAAT
CGGATGGACGAGGTCTGGAA

Downstream 100 bases:

>100_bases
AAATCCCGTAAACACATACACTTGGGTGCCTCTCACAATCCAAGATGAATCGGAAACATTATTAAATATCGTTTCTGCAG
AAAAAGAATTTGTAACTGAT

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIKLALMGQAFYVTGTGTDVGKTFFSSLFMAKYAKKYGFRYWKPIQTGSISADDTTFVQKTTSLPDSYFLKPNYVFKTPA
SPHYAAKIEGQTIDPKSLLSSVSKERKTNTLIEGAGGVFVPITEDYLTIRAIQESNLGVVVVGSTELGTINHTLMTLEVL
TSRFIPVFGFYLVGPENSLQEDNATMIQRLGGASFLGFTNFPEQKLTSDEFIRFASEHFDPNRNVIDVVLNADEE

Sequences:

>Translated_235_residues
MIKLALMGQAFYVTGTGTDVGKTFFSSLFMAKYAKKYGFRYWKPIQTGSISADDTTFVQKTTSLPDSYFLKPNYVFKTPA
SPHYAAKIEGQTIDPKSLLSSVSKERKTNTLIEGAGGVFVPITEDYLTIRAIQESNLGVVVVGSTELGTINHTLMTLEVL
TSRFIPVFGFYLVGPENSLQEDNATMIQRLGGASFLGFTNFPEQKLTSDEFIRFASEHFDPNRNVIDVVLNADEE
>Mature_235_residues
MIKLALMGQAFYVTGTGTDVGKTFFSSLFMAKYAKKYGFRYWKPIQTGSISADDTTFVQKTTSLPDSYFLKPNYVFKTPA
SPHYAAKIEGQTIDPKSLLSSVSKERKTNTLIEGAGGVFVPITEDYLTIRAIQESNLGVVVVGSTELGTINHTLMTLEVL
TSRFIPVFGFYLVGPENSLQEDNATMIQRLGGASFLGFTNFPEQKLTSDEFIRFASEHFDPNRNVIDVVLNADEE

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=205, Percent_Identity=30.2439024390244, Blast_Score=88, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324385, Length=197, Percent_Identity=36.0406091370558, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26033; Mature: 26033

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLALMGQAFYVTGTGTDVGKTFFSSLFMAKYAKKYGFRYWKPIQTGSISADDTTFVQK
CEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEH
TTSLPDSYFLKPNYVFKTPASPHYAAKIEGQTIDPKSLLSSVSKERKTNTLIEGAGGVFV
HCCCCCCEEECCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCEEE
PITEDYLTIRAIQESNLGVVVVGSTELGTINHTLMTLEVLTSRFIPVFGFYLVGPENSLQ
EECCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCC
EDNATMIQRLGGASFLGFTNFPEQKLTSDEFIRFASEHFDPNRNVIDVVLNADEE
CCHHHHHHHCCCCEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MIKLALMGQAFYVTGTGTDVGKTFFSSLFMAKYAKKYGFRYWKPIQTGSISADDTTFVQK
CEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEH
TTSLPDSYFLKPNYVFKTPASPHYAAKIEGQTIDPKSLLSSVSKERKTNTLIEGAGGVFV
HCCCCCCEEECCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCEEE
PITEDYLTIRAIQESNLGVVVVGSTELGTINHTLMTLEVLTSRFIPVFGFYLVGPENSLQ
EECCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCC
EDNATMIQRLGGASFLGFTNFPEQKLTSDEFIRFASEHFDPNRNVIDVVLNADEE
CCHHHHHHHCCCCEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA