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The map label for this gene is atpB [H]

Identifier: 183220209

GI number: 183220209

Start: 816568

End: 817497

Strand: Direct

Name: atpB [H]

Synonym: LEPBI_I0801

Alternate gene names: 183220209

Gene position: 816568-817497 (Clockwise)

Preceding gene: 183220208

Following gene: 183220210

Centisome position: 22.68

GC content: 43.98

Gene sequence:

>930_bases
ATGGCGCACCACTTAGGTGATGCTCCCATCTTCCCTCTCAACTTCGGTGGCACAATTGTCACAGAAGGCCAACCTGGTTA
CGATGCGGAAAACCATGATGTGTTTGTGAACCACGATGGAGTGAAGTATCACTACGTTGGTGGACTTGACTTACATATCA
CCAAACGAGTGACCATGATGTGGATTGCTTGTTTCTTTATGTTTCTCGTTTTTATCCCAGCGGCAAACCTGATCTCTAAG
AACCCAAAAAAGGTTCACAATAAATTCACATCAGGTGTAGAAGCATTTGTAAGTTACTTAAAAGAAAACGTTGTGGACTC
CTCACTCGACCACCACGGACATTCGTATTACCACTACATCTTCTCATTGTTTTTCTTTATCCTTTTCTGTAACTTGTTTG
GCCTCATCCCATCGGTTGGTGAGCTTACAGTTGCCGCATCGGATGGACTTGTTGCTCTTGGTGTTATGGACCACACACCC
CACGCACTCCATACATTCGGAGAAGTTTGGTCAGGCATCACACCAACAGGGGACATTAGTGTTACCCTTTCACTTGCATC
CATTACCTTACTCACTATTTACGGAACCGCATTCTCTTACCAAGGGATCTCCTTCGTAGCCCATGCTGTTCCTAAGGGTG
TTCCTCTTTTACTATGGCCACTCATGTGGGCATTGGAATTTATCGTAACTCACATCGCTCGCTCTTTTGCGTTAACGATG
AGGTTACTAGCCAATATGACAGCAGGACACGTTATGATCCTTGCGTTACTTGGGTTTATTTTTATGAGCGAAAGTTGGCT
CATTGCACCTGTATCTGTTCTCAGTTCAGTGCTCATTTACTTTTTAGAACTACTTGTAGCATTTCTACAAGCGTTCATTT
TCTCACTGCTCACAACCGTCTTCATCGGAACTGTGATGCATAGACATTAA

Upstream 100 bases:

>100_bases
TTTATCATTTTTATTAGTTTTTTCCCTTAGTTTTACGAATGTTTTTGCAAACGATTCGGAAGGGCACAGCTCTGATGAGG
GCTTCGATTTCAGCGAAGTG

Downstream 100 bases:

>100_bases
GATTGGTTTTATTTATATTATAAAACACACAGGAGTGAAACGAAAACAATGGAATTCGGTTTAGGATACATCGCAGTAGG
ACTCGCAGCAGGACTTGCAT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAHHLGDAPIFPLNFGGTIVTEGQPGYDAENHDVFVNHDGVKYHYVGGLDLHITKRVTMMWIACFFMFLVFIPAANLISK
NPKKVHNKFTSGVEAFVSYLKENVVDSSLDHHGHSYYHYIFSLFFFILFCNLFGLIPSVGELTVAASDGLVALGVMDHTP
HALHTFGEVWSGITPTGDISVTLSLASITLLTIYGTAFSYQGISFVAHAVPKGVPLLLWPLMWALEFIVTHIARSFALTM
RLLANMTAGHVMILALLGFIFMSESWLIAPVSVLSSVLIYFLELLVAFLQAFIFSLLTTVFIGTVMHRH

Sequences:

>Translated_309_residues
MAHHLGDAPIFPLNFGGTIVTEGQPGYDAENHDVFVNHDGVKYHYVGGLDLHITKRVTMMWIACFFMFLVFIPAANLISK
NPKKVHNKFTSGVEAFVSYLKENVVDSSLDHHGHSYYHYIFSLFFFILFCNLFGLIPSVGELTVAASDGLVALGVMDHTP
HALHTFGEVWSGITPTGDISVTLSLASITLLTIYGTAFSYQGISFVAHAVPKGVPLLLWPLMWALEFIVTHIARSFALTM
RLLANMTAGHVMILALLGFIFMSESWLIAPVSVLSSVLIYFLELLVAFLQAFIFSLLTTVFIGTVMHRH
>Mature_308_residues
AHHLGDAPIFPLNFGGTIVTEGQPGYDAENHDVFVNHDGVKYHYVGGLDLHITKRVTMMWIACFFMFLVFIPAANLISKN
PKKVHNKFTSGVEAFVSYLKENVVDSSLDHHGHSYYHYIFSLFFFILFCNLFGLIPSVGELTVAASDGLVALGVMDHTPH
ALHTFGEVWSGITPTGDISVTLSLASITLLTIYGTAFSYQGISFVAHAVPKGVPLLLWPLMWALEFIVTHIARSFALTMR
LLANMTAGHVMILALLGFIFMSESWLIAPVSVLSSVLIYFLELLVAFLQAFIFSLLTTVFIGTVMHRH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 34197; Mature: 34065

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHHLGDAPIFPLNFGGTIVTEGQPGYDAENHDVFVNHDGVKYHYVGGLDLHITKRVTMM
CCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCEEEECCCEEEEEECCEEEEHHHHHHHH
WIACFFMFLVFIPAANLISKNPKKVHNKFTSGVEAFVSYLKENVVDSSLDHHGHSYYHYI
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FSLFFFILFCNLFGLIPSVGELTVAASDGLVALGVMDHTPHALHTFGEVWSGITPTGDIS
HHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEE
VTLSLASITLLTIYGTAFSYQGISFVAHAVPKGVPLLLWPLMWALEFIVTHIARSFALTM
EEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLANMTAGHVMILALLGFIFMSESWLIAPVSVLSSVLIYFLELLVAFLQAFIFSLLTTV
HHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGTVMHRH
HHHHHHHCC
>Mature Secondary Structure 
AHHLGDAPIFPLNFGGTIVTEGQPGYDAENHDVFVNHDGVKYHYVGGLDLHITKRVTMM
CCCCCCCCEEEEECCCEEEECCCCCCCCCCCCEEEECCCEEEEEECCEEEEHHHHHHHH
WIACFFMFLVFIPAANLISKNPKKVHNKFTSGVEAFVSYLKENVVDSSLDHHGHSYYHYI
HHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FSLFFFILFCNLFGLIPSVGELTVAASDGLVALGVMDHTPHALHTFGEVWSGITPTGDIS
HHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEE
VTLSLASITLLTIYGTAFSYQGISFVAHAVPKGVPLLLWPLMWALEFIVTHIARSFALTM
EEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLANMTAGHVMILALLGFIFMSESWLIAPVSVLSSVLIYFLELLVAFLQAFIFSLLTTV
HHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIGTVMHRH
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA