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The map label for this gene is 183220022

Identifier: 183220022

GI number: 183220022

Start: 608599

End: 610212

Strand: Reverse

Name: 183220022

Synonym: LEPBI_I0606

Alternate gene names: NA

Gene position: 610212-608599 (Counterclockwise)

Preceding gene: 183220038

Following gene: 183220021

Centisome position: 16.95

GC content: 40.02

Gene sequence:

>1614_bases
ATGGAGATCAAAAAATACGATGTGACGATCATCGGCGCTGGAATTGCAGGGATGGTTGCCGCATACGAATGTTTAAATAA
AGGTTTGAAGGTTTTACTCATAGATCGGAACACAAAAGAACATTTTGGTGGACTCGCAAAACTTTCCTTTGGTGGAATGG
CATTGGTAAATACCCCACTACAAAGAAGATTAGGGATTAAAGATTCACCATCAATCGCTTTAAAAGACTGGCATTCCTTT
GCCAATTTCAAAAAAGAAGATCGATTCCCGAAACTTTGGGCCGAGATGTATGTGAATGAAAGTTTAGGACAGGTATACCA
CTGGCTTTATGGATTTGGATTAAAATTTTTTCCAGCTGTGAATTGGGTGGAAAGAGGAATGTACCAAAGCGGAAATTCCG
TTCCCAGATACCATGTTCTTTGGGGTACAGGGCATAGATTAGTAGAACGGTTCCAAGAACTATTACTCCAACACCAAAAC
GTTCGCAAATTAGAAATCATTTTTGAATGCAAAGTTACTGATCTCATCAAAGAAAACGAAAAAATCATAGGTTGCACTGC
TGAAAAAGAAGGAATCAAAAATCAAAAATTCAGGTTTCATTCTGATTTTACCATTGTGGCAACTGGTGGAATAACAGGAA
ACTTAGAAGCCGTAAGAAACAATTGGTACAAACCTTGGGGGAAAGCACCTAACGAAATGTTAAATGGATCACATCCGTTT
GCAGATGGGTTAGTACATACAGCTGTGAGTCGGCTTGGTGGGAATGTCACTCACTTAGATAAAATGTGGAATTATGCTGC
TGGAATTCCACATCCAAAACCTGAATTTGATCACCATGGATTGAGTTTGATCCCTTGTAAATCAGCATTATGGTTGGATC
ATACTGGCAATCGAATTGGACCAGAGCCACTAGTGACAGGGTATGACACAAATGAACTTTGCCGTCGCATTTCAAGTTTG
GAAAAACCATACACTTGGCAAGTGTTAAACTGGAAGATTGCATCAAAGGAATTAGCAGTCTCCGGATCGGAACACAATCC
AATGATCAGGGATCGAAAACTATTTTCCTTTCTGAAAGAGATCCTCTTTGGAAACCATCGATTGATTCACCAACTTAAAA
AAGAAAGTGATCACTTCATCGTTGCAGATGATTTACAAACATTGGTAAAAGAAATGAATCATTTAAACCAAGACAGTTCC
ATTGATTATGATGTGATCCATGACGTAATTCGTTCTTATGATGAAATGATCAAACGAGGGAAATCTTTTTGGAATGATGA
GCAAATCAGAAAGATCCAACAAGCGCGAGCTTGGCGATCTGAAAAATTTCGCACCTGCTCTCCAAAACCGATTCTCAATG
CAAACTCAGGGCCACTCATTGCCATTAAGTTACGACTCATCACAAGGAAAAGTTTAGGTGGAATCCAAACGGATTTAGAG
AGCCGTGTTTTAGATCCTTTGGGAAACCCAATACCAGGTTTGTATGCGATCGGTGAAGCTGCAGGGTTTGGTGGTGGGGG
AGCGAGTGGCTTCAAGTCGTTGGAAGGAACATTTTTATCAGGGTGTATCCTTACGGCACGAAGTGCAGCAAAATCAATCT
GTAGTTTAAAATAG

Upstream 100 bases:

>100_bases
ACACTTTGTTACAAAAATTCGATATACCGTATCGGAAGTAATCATTCCTTACAGTCGTACCTAAATGGATTATGAAGAAT
TTAAAAAAGGAGAATCGTAA

Downstream 100 bases:

>100_bases
ATGTTCGTGATATTTAAGGAGATACTGTTATGAAAAAAACTGGCGCATGGTTATTACGTTTTGCACTCGAAGAAATTGGA
GTGCGTTATACATTCGGAAT

Product: putative FAD binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MEIKKYDVTIIGAGIAGMVAAYECLNKGLKVLLIDRNTKEHFGGLAKLSFGGMALVNTPLQRRLGIKDSPSIALKDWHSF
ANFKKEDRFPKLWAEMYVNESLGQVYHWLYGFGLKFFPAVNWVERGMYQSGNSVPRYHVLWGTGHRLVERFQELLLQHQN
VRKLEIIFECKVTDLIKENEKIIGCTAEKEGIKNQKFRFHSDFTIVATGGITGNLEAVRNNWYKPWGKAPNEMLNGSHPF
ADGLVHTAVSRLGGNVTHLDKMWNYAAGIPHPKPEFDHHGLSLIPCKSALWLDHTGNRIGPEPLVTGYDTNELCRRISSL
EKPYTWQVLNWKIASKELAVSGSEHNPMIRDRKLFSFLKEILFGNHRLIHQLKKESDHFIVADDLQTLVKEMNHLNQDSS
IDYDVIHDVIRSYDEMIKRGKSFWNDEQIRKIQQARAWRSEKFRTCSPKPILNANSGPLIAIKLRLITRKSLGGIQTDLE
SRVLDPLGNPIPGLYAIGEAAGFGGGGASGFKSLEGTFLSGCILTARSAAKSICSLK

Sequences:

>Translated_537_residues
MEIKKYDVTIIGAGIAGMVAAYECLNKGLKVLLIDRNTKEHFGGLAKLSFGGMALVNTPLQRRLGIKDSPSIALKDWHSF
ANFKKEDRFPKLWAEMYVNESLGQVYHWLYGFGLKFFPAVNWVERGMYQSGNSVPRYHVLWGTGHRLVERFQELLLQHQN
VRKLEIIFECKVTDLIKENEKIIGCTAEKEGIKNQKFRFHSDFTIVATGGITGNLEAVRNNWYKPWGKAPNEMLNGSHPF
ADGLVHTAVSRLGGNVTHLDKMWNYAAGIPHPKPEFDHHGLSLIPCKSALWLDHTGNRIGPEPLVTGYDTNELCRRISSL
EKPYTWQVLNWKIASKELAVSGSEHNPMIRDRKLFSFLKEILFGNHRLIHQLKKESDHFIVADDLQTLVKEMNHLNQDSS
IDYDVIHDVIRSYDEMIKRGKSFWNDEQIRKIQQARAWRSEKFRTCSPKPILNANSGPLIAIKLRLITRKSLGGIQTDLE
SRVLDPLGNPIPGLYAIGEAAGFGGGGASGFKSLEGTFLSGCILTARSAAKSICSLK
>Mature_537_residues
MEIKKYDVTIIGAGIAGMVAAYECLNKGLKVLLIDRNTKEHFGGLAKLSFGGMALVNTPLQRRLGIKDSPSIALKDWHSF
ANFKKEDRFPKLWAEMYVNESLGQVYHWLYGFGLKFFPAVNWVERGMYQSGNSVPRYHVLWGTGHRLVERFQELLLQHQN
VRKLEIIFECKVTDLIKENEKIIGCTAEKEGIKNQKFRFHSDFTIVATGGITGNLEAVRNNWYKPWGKAPNEMLNGSHPF
ADGLVHTAVSRLGGNVTHLDKMWNYAAGIPHPKPEFDHHGLSLIPCKSALWLDHTGNRIGPEPLVTGYDTNELCRRISSL
EKPYTWQVLNWKIASKELAVSGSEHNPMIRDRKLFSFLKEILFGNHRLIHQLKKESDHFIVADDLQTLVKEMNHLNQDSS
IDYDVIHDVIRSYDEMIKRGKSFWNDEQIRKIQQARAWRSEKFRTCSPKPILNANSGPLIAIKLRLITRKSLGGIQTDLE
SRVLDPLGNPIPGLYAIGEAAGFGGGGASGFKSLEGTFLSGCILTARSAAKSICSLK

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids [H]

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=536, Percent_Identity=23.3208955223881, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60535; Mature: 60535

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKKYDVTIIGAGIAGMVAAYECLNKGLKVLLIDRNTKEHFGGLAKLSFGGMALVNTPL
CCCEEEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCEEEECCCCCCEECCCH
QRRLGIKDSPSIALKDWHSFANFKKEDRFPKLWAEMYVNESLGQVYHWLYGFGLKFFPAV
HHHCCCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NWVERGMYQSGNSVPRYHVLWGTGHRLVERFQELLLQHQNVRKLEIIFECKVTDLIKENE
HHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHCCC
KIIGCTAEKEGIKNQKFRFHSDFTIVATGGITGNLEAVRNNWYKPWGKAPNEMLNGSHPF
EEEEECCHHCCCCCCCEEEECCEEEEEECCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCH
ADGLVHTAVSRLGGNVTHLDKMWNYAAGIPHPKPEFDHHGLSLIPCKSALWLDHTGNRIG
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCC
PEPLVTGYDTNELCRRISSLEKPYTWQVLNWKIASKELAVSGSEHNPMIRDRKLFSFLKE
CCCCEECCCHHHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCCCCCHHHHHHHHHHHH
ILFGNHRLIHQLKKESDHFIVADDLQTLVKEMNHLNQDSSIDYDVIHDVIRSYDEMIKRG
HHCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KSFWNDEQIRKIQQARAWRSEKFRTCSPKPILNANSGPLIAIKLRLITRKSLGGIQTDLE
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHCCCHHHHHH
SRVLDPLGNPIPGLYAIGEAAGFGGGGASGFKSLEGTFLSGCILTARSAAKSICSLK
HHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIKKYDVTIIGAGIAGMVAAYECLNKGLKVLLIDRNTKEHFGGLAKLSFGGMALVNTPL
CCCEEEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCEEEECCCCCCEECCCH
QRRLGIKDSPSIALKDWHSFANFKKEDRFPKLWAEMYVNESLGQVYHWLYGFGLKFFPAV
HHHCCCCCCCCCHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NWVERGMYQSGNSVPRYHVLWGTGHRLVERFQELLLQHQNVRKLEIIFECKVTDLIKENE
HHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHCCC
KIIGCTAEKEGIKNQKFRFHSDFTIVATGGITGNLEAVRNNWYKPWGKAPNEMLNGSHPF
EEEEECCHHCCCCCCCEEEECCEEEEEECCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCH
ADGLVHTAVSRLGGNVTHLDKMWNYAAGIPHPKPEFDHHGLSLIPCKSALWLDHTGNRIG
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCC
PEPLVTGYDTNELCRRISSLEKPYTWQVLNWKIASKELAVSGSEHNPMIRDRKLFSFLKE
CCCCEECCCHHHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCCCCCHHHHHHHHHHHH
ILFGNHRLIHQLKKESDHFIVADDLQTLVKEMNHLNQDSSIDYDVIHDVIRSYDEMIKRG
HHCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
KSFWNDEQIRKIQQARAWRSEKFRTCSPKPILNANSGPLIAIKLRLITRKSLGGIQTDLE
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHCCCHHHHHH
SRVLDPLGNPIPGLYAIGEAAGFGGGGASGFKSLEGTFLSGCILTARSAAKSICSLK
HHHHHHCCCCCCCHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]