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The map label for this gene is glcD [H]

Identifier: 183219996

GI number: 183219996

Start: 579167

End: 580579

Strand: Reverse

Name: glcD [H]

Synonym: LEPBI_I0578

Alternate gene names: 183219996

Gene position: 580579-579167 (Counterclockwise)

Preceding gene: 183219997

Following gene: 183219995

Centisome position: 16.13

GC content: 41.05

Gene sequence:

>1413_bases
ATGGATTTTACAAAAACAAAAACAGAACTAGGGTTACTCATTGGAGAAAAAAAAGTCATCCAAAAAAAAGATGGAACGAT
GGATGATGCTTTGTTTGATTCTTATGGAACAGACAGGACCAAAGTATACCCACCCAATTATCAAATTCTAGTATTCCCTG
AAACCACAGACGATGTGGCCTCCATCGTTTCTTATGCTTATAAAAATGGAATTTCCATCGTTCCTTCTGGTGGTAGAACA
GGGTATGCTGGTGGCGCCGTTGCCAAAAATGATGAAATTGTCATTTCTTTGAACAAAATGAACCAAGTTTTAGATTTTGA
TCCCTTCCTTGGCACCTTACACATCCAAGCTGGTATGATCACAAAAAACTTACACAAAGAAGCAGAAGAGAGAGGATTTT
ATTTTCCCGTTGATTTTGCTGCCACTGGATCGAGCCATATTGGAGGAAACATAGCCACCAATGCAGGTGGAGTTCGTGTG
GTACGGTATGGCCTCATCCGAGATTGGGTCTTAGGTCTCACCGTTGTGACAGGAAAAGGAGAAGTGTTTCGCTTCAACGG
TGAAATCCTGAAAAACAATACAGGTTATGATTTAAAACATTTGTTTATTGGATCGGAAGGAACACTTGGGATCATCACAG
AAGCGGTTGTCAAACTCACAAAACCACCAAAAGACATCCGTGTGATATTTTTAGCAGTACCTGAATACAAAAACATTTTA
GAAATCTTTCGTGAAACACATAACTTTGATTTACCTCTGCTTGCATTTGAATTTTTGACTGATTATTGTTTGGATAAAGT
AAAAGAACACTTAGGAGTCCCGGATCCATTCCAAGCACCGAGCAAGTATTATGTGCTCATGGAATTTGAAGTGAGTGGAG
AATCTGACGAGGAAAAACTCTATTCGATTTTGGAATCCATTACAGAAAAGGAACTCATCACAGATGGTTCTATCGCACAA
AACTCAAGGCAAAATGAAACCTTTTGGAAGTACCGCGAAGGGATTTCGGAATCACTCTCTCTCGCCTATACCGTTCATAA
AAATGATATCTCCCTCCCCCTTCGCAATATGGAGGCATTTTTAGATGAGATGACTACCCTTCTCACAAACAAATACCAAG
GATTTTCCATTGCCCTCTTTGGGCATATTGGGGACGGGAACCTCCACCTCAATATCGTAAAACCGAAAGAACTCTCGGAT
GCCGACTTTTTCCAACAATGCAAACAAGTGGACCCAGATATGTTCCAACTCATCCAAAAATTCAAAGGTTCCATCTCCGC
AGAACATGGAATTGGTCTTTTGAAAAAGGATTATCTTGGATTCTCTCGTTCCGCCTCGGAATTGGACACGATGCGAGCCA
TCAAACTGGCCTTTGACCCCAAGGGGATTCTCAATCCCGGCAAAGTGCTTTGA

Upstream 100 bases:

>100_bases
GTGTTGGAATCGGATGGATCTTATACAAGGCTCGCACCAGGTGATGATGATCCTGCTGTGAATGCACAAATTGACATGGT
TGATATCTAAAGGAACCAAA

Downstream 100 bases:

>100_bases
TTCAAGACAATCCGTTGGTCCTTCTAAATTTTTTGGTCGATCTGCTTAAAATATAGGCAATGGCCAAAAAAATGCTAGAT
TTTAATCAGAGACCGTCTAA

Product: putative FAD dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MDFTKTKTELGLLIGEKKVIQKKDGTMDDALFDSYGTDRTKVYPPNYQILVFPETTDDVASIVSYAYKNGISIVPSGGRT
GYAGGAVAKNDEIVISLNKMNQVLDFDPFLGTLHIQAGMITKNLHKEAEERGFYFPVDFAATGSSHIGGNIATNAGGVRV
VRYGLIRDWVLGLTVVTGKGEVFRFNGEILKNNTGYDLKHLFIGSEGTLGIITEAVVKLTKPPKDIRVIFLAVPEYKNIL
EIFRETHNFDLPLLAFEFLTDYCLDKVKEHLGVPDPFQAPSKYYVLMEFEVSGESDEEKLYSILESITEKELITDGSIAQ
NSRQNETFWKYREGISESLSLAYTVHKNDISLPLRNMEAFLDEMTTLLTNKYQGFSIALFGHIGDGNLHLNIVKPKELSD
ADFFQQCKQVDPDMFQLIQKFKGSISAEHGIGLLKKDYLGFSRSASELDTMRAIKLAFDPKGILNPGKVL

Sequences:

>Translated_470_residues
MDFTKTKTELGLLIGEKKVIQKKDGTMDDALFDSYGTDRTKVYPPNYQILVFPETTDDVASIVSYAYKNGISIVPSGGRT
GYAGGAVAKNDEIVISLNKMNQVLDFDPFLGTLHIQAGMITKNLHKEAEERGFYFPVDFAATGSSHIGGNIATNAGGVRV
VRYGLIRDWVLGLTVVTGKGEVFRFNGEILKNNTGYDLKHLFIGSEGTLGIITEAVVKLTKPPKDIRVIFLAVPEYKNIL
EIFRETHNFDLPLLAFEFLTDYCLDKVKEHLGVPDPFQAPSKYYVLMEFEVSGESDEEKLYSILESITEKELITDGSIAQ
NSRQNETFWKYREGISESLSLAYTVHKNDISLPLRNMEAFLDEMTTLLTNKYQGFSIALFGHIGDGNLHLNIVKPKELSD
ADFFQQCKQVDPDMFQLIQKFKGSISAEHGIGLLKKDYLGFSRSASELDTMRAIKLAFDPKGILNPGKVL
>Mature_470_residues
MDFTKTKTELGLLIGEKKVIQKKDGTMDDALFDSYGTDRTKVYPPNYQILVFPETTDDVASIVSYAYKNGISIVPSGGRT
GYAGGAVAKNDEIVISLNKMNQVLDFDPFLGTLHIQAGMITKNLHKEAEERGFYFPVDFAATGSSHIGGNIATNAGGVRV
VRYGLIRDWVLGLTVVTGKGEVFRFNGEILKNNTGYDLKHLFIGSEGTLGIITEAVVKLTKPPKDIRVIFLAVPEYKNIL
EIFRETHNFDLPLLAFEFLTDYCLDKVKEHLGVPDPFQAPSKYYVLMEFEVSGESDEEKLYSILESITEKELITDGSIAQ
NSRQNETFWKYREGISESLSLAYTVHKNDISLPLRNMEAFLDEMTTLLTNKYQGFSIALFGHIGDGNLHLNIVKPKELSD
ADFFQQCKQVDPDMFQLIQKFKGSISAEHGIGLLKKDYLGFSRSASELDTMRAIKLAFDPKGILNPGKVL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=425, Percent_Identity=39.7647058823529, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI37595756, Length=463, Percent_Identity=27.4298056155508, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI37595754, Length=486, Percent_Identity=27.1604938271605, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI4501993, Length=229, Percent_Identity=31.0043668122271, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1789351, Length=442, Percent_Identity=28.2805429864253, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787977, Length=514, Percent_Identity=24.9027237354086, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI48994914, Length=123, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994907, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=443, Percent_Identity=35.665914221219, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71992373, Length=462, Percent_Identity=25.1082251082251, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71992381, Length=462, Percent_Identity=24.4588744588745, Blast_Score=145, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71992392, Length=353, Percent_Identity=26.9121813031161, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17556096, Length=202, Percent_Identity=26.2376237623762, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320023, Length=446, Percent_Identity=36.0986547085202, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6320764, Length=448, Percent_Identity=33.9285714285714, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6320027, Length=458, Percent_Identity=27.0742358078603, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI18921117, Length=427, Percent_Identity=37.7049180327869, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24639277, Length=427, Percent_Identity=37.7049180327869, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24639275, Length=427, Percent_Identity=37.7049180327869, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24653753, Length=201, Percent_Identity=29.3532338308458, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 52426; Mature: 52426

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTKTKTELGLLIGEKKVIQKKDGTMDDALFDSYGTDRTKVYPPNYQILVFPETTDDVA
CCCCCCHHHHHHEECCHHHHHCCCCCHHHHHHHCCCCCCCEEECCCEEEEEECCCCHHHH
SIVSYAYKNGISIVPSGGRTGYAGGAVAKNDEIVISLNKMNQVLDFDPFLGTLHIQAGMI
HHHHHHHHCCCEEEECCCCCCCCCCCEECCCCEEEEEHHCCHHHCCCCCCEEEEEEECHH
TKNLHKEAEERGFYFPVDFAATGSSHIGGNIATNAGGVRVVRYGLIRDWVLGLTVVTGKG
HHHHHHHHHHCCCEEEEEHCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHEEEEEECCC
EVFRFNGEILKNNTGYDLKHLFIGSEGTLGIITEAVVKLTKPPKDIRVIFLAVPEYKNIL
CEEEECCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHH
EIFRETHNFDLPLLAFEFLTDYCLDKVKEHLGVPDPFQAPSKYYVLMEFEVSGESDEEKL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCHHHH
YSILESITEKELITDGSIAQNSRQNETFWKYREGISESLSLAYTVHKNDISLPLRNMEAF
HHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHCHHHCCEEEEEEECCCCCCCHHHHHHH
LDEMTTLLTNKYQGFSIALFGHIGDGNLHLNIVKPKELSDADFFQQCKQVDPDMFQLIQK
HHHHHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHH
FKGSISAEHGIGLLKKDYLGFSRSASELDTMRAIKLAFDPKGILNPGKVL
HCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDFTKTKTELGLLIGEKKVIQKKDGTMDDALFDSYGTDRTKVYPPNYQILVFPETTDDVA
CCCCCCHHHHHHEECCHHHHHCCCCCHHHHHHHCCCCCCCEEECCCEEEEEECCCCHHHH
SIVSYAYKNGISIVPSGGRTGYAGGAVAKNDEIVISLNKMNQVLDFDPFLGTLHIQAGMI
HHHHHHHHCCCEEEECCCCCCCCCCCEECCCCEEEEEHHCCHHHCCCCCCEEEEEEECHH
TKNLHKEAEERGFYFPVDFAATGSSHIGGNIATNAGGVRVVRYGLIRDWVLGLTVVTGKG
HHHHHHHHHHCCCEEEEEHCCCCCCCCCCEEEECCCCEEEEHHHHHHHHHHEEEEEECCC
EVFRFNGEILKNNTGYDLKHLFIGSEGTLGIITEAVVKLTKPPKDIRVIFLAVPEYKNIL
CEEEECCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHH
EIFRETHNFDLPLLAFEFLTDYCLDKVKEHLGVPDPFQAPSKYYVLMEFEVSGESDEEKL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCHHHH
YSILESITEKELITDGSIAQNSRQNETFWKYREGISESLSLAYTVHKNDISLPLRNMEAF
HHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHCHHHCCEEEEEEECCCCCCCHHHHHHH
LDEMTTLLTNKYQGFSIALFGHIGDGNLHLNIVKPKELSDADFFQQCKQVDPDMFQLIQK
HHHHHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHH
FKGSISAEHGIGLLKKDYLGFSRSASELDTMRAIKLAFDPKGILNPGKVL
HCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]