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The map label for this gene is hflX [H]

Identifier: 183219489

GI number: 183219489

Start: 62138

End: 63694

Strand: Direct

Name: hflX [H]

Synonym: LEPBI_I0062

Alternate gene names: 183219489

Gene position: 62138-63694 (Clockwise)

Preceding gene: 183219487

Following gene: 183219492

Centisome position: 1.73

GC content: 41.23

Gene sequence:

>1557_bases
ATGGAGCTTGCAAGGCTTGTCGGAGAGATATCTGTCGAAATGGGAAGGCAGGTAGGCCTCCTCATAGAGAGGACGGGTTA
TGTCACTCATCTCATTGTCGGTAATGACCATTCCATCGAAATTCCCCATTTAGACCGCTATCGTGTCGCACATTCCAGGC
TTCGTGGCCTTCGTTTGTTTCATACTCATCTCAAAGAACAGCCGTTAAACCAAGAAGACTTGATGGACCTTGTCCTCAAC
CGATTTGATTCCATCACGGCCGCTTGTGTGGACAAAGAGGGAATCCCAAAATTCTTTTTTTCTGCCTTCATCAATCCAGA
CCCAGATGCAAAAGAACCCTGGATCTTATCACCCAAACAATACCCTGGACAAATTAAGTATGGGTATTCAGAACAAGTAG
ACGCACTCGAATCCGAATTCACTAAAAAGACATCCAACCTCAAAGAATCTCAAAAAGAAAATAGAGCTTTCCTTGTGGGA
GTGTATGATGTGAGAAAAATGAAACGTTCTCCCGAACATTCTATGGATGAATTAAAAGAACTCTGTAGGACGGCTGGTAT
TCATGTTGTGGATACCTATGTACAAAAAAGAGATCCTGATCCTAGGACAGTTGTGGGAAAAGGGAAATTACAAGAAATCA
TTCTCACTTCGGTTCATAAAGACATAGAACATTTGATTTTTGATTTGGAACTCACTCCTTCCCAAGCTAAAAAAATCTCG
GATGCAAGTGACTTAAAAATCATCGACCGAACCCAACTCATATTAGATATCTTTTCCAAAAATGCCAAGTCACGAGATGG
AAAGTTACAAGTAGAACTTGCTCAGTTGAAATACCTTAAAAATCGACTCTCCGAGTTGGATGATAATATGAGTCGTCTAA
CGGGTGGAATCGGTGGAAGGGGACCTGGGGAAACCAAATTAGAAATTGGAAACAGACGTGTTGAAGAAAAAATCAATCGT
TTGGAAAATGAACTAAAGGATCTCAAACGAAGAAGGGAACTCAATCGTAAGTCTCGTTCTCGTAATGAAATTCCGATCGT
GGGGATTGTGGGTTACACCAATGCAGGCAAATCAACCTTACTCAACGCCCTAACCAATTCCACAGTCATTGCCGAAGACA
AACTTTTTGCCACTCTTGATCCCACTACGAGAAGGATCCGGTTTCCTGAGGAAAGAGAAATCATCATTTCCGATACGGTA
GGATTCATCCATGATCTTCCTCCCGATCTGTCGCAAGCATTCAAAGCCACTTTAGAAGAATTAGGTGATGCCGACTTACT
CTTACATGTAGTCGATGTCACCAATCCAAATTATACAGAACAAATGGATGCTGTTGATACCATTTTGAATTCACTTCATT
TGAACGAGATTCCAAGAATGGTGGTGTTTAATAAAGCCGATGGACTGGATGAAGAAACACACGATATCTTACAAAAAAAT
GGCGCCTTACTTGTGTCTGCTGTGACGAGAGAAGGCCTTTCCAAATTGTTAGATTTGATCGAGTATGAGATTTGGAAAAA
GAAGGAACAAAAATTATTGGAAGTTACGTCCAGTTGA

Upstream 100 bases:

>100_bases
AAGTAAAATTAGCGGCAACCTCGCTGGTCTCAAGCCAAACCAGCTAAAAAAGTTAAAATCTCTCTCAGAAAGGCGACTTC
GAGAGGATTCTATCATCTCC

Downstream 100 bases:

>100_bases
GGATGGCTTCCTCTTTTGTATGGTAAATCTGCACTTTTTTTGGAAGGTCCATCAGTTGGATCACATTTTCCAAAAAATGA
TTTAGACCTCCAATCTTAAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MELARLVGEISVEMGRQVGLLIERTGYVTHLIVGNDHSIEIPHLDRYRVAHSRLRGLRLFHTHLKEQPLNQEDLMDLVLN
RFDSITAACVDKEGIPKFFFSAFINPDPDAKEPWILSPKQYPGQIKYGYSEQVDALESEFTKKTSNLKESQKENRAFLVG
VYDVRKMKRSPEHSMDELKELCRTAGIHVVDTYVQKRDPDPRTVVGKGKLQEIILTSVHKDIEHLIFDLELTPSQAKKIS
DASDLKIIDRTQLILDIFSKNAKSRDGKLQVELAQLKYLKNRLSELDDNMSRLTGGIGGRGPGETKLEIGNRRVEEKINR
LENELKDLKRRRELNRKSRSRNEIPIVGIVGYTNAGKSTLLNALTNSTVIAEDKLFATLDPTTRRIRFPEEREIIISDTV
GFIHDLPPDLSQAFKATLEELGDADLLLHVVDVTNPNYTEQMDAVDTILNSLHLNEIPRMVVFNKADGLDEETHDILQKN
GALLVSAVTREGLSKLLDLIEYEIWKKKEQKLLEVTSS

Sequences:

>Translated_518_residues
MELARLVGEISVEMGRQVGLLIERTGYVTHLIVGNDHSIEIPHLDRYRVAHSRLRGLRLFHTHLKEQPLNQEDLMDLVLN
RFDSITAACVDKEGIPKFFFSAFINPDPDAKEPWILSPKQYPGQIKYGYSEQVDALESEFTKKTSNLKESQKENRAFLVG
VYDVRKMKRSPEHSMDELKELCRTAGIHVVDTYVQKRDPDPRTVVGKGKLQEIILTSVHKDIEHLIFDLELTPSQAKKIS
DASDLKIIDRTQLILDIFSKNAKSRDGKLQVELAQLKYLKNRLSELDDNMSRLTGGIGGRGPGETKLEIGNRRVEEKINR
LENELKDLKRRRELNRKSRSRNEIPIVGIVGYTNAGKSTLLNALTNSTVIAEDKLFATLDPTTRRIRFPEEREIIISDTV
GFIHDLPPDLSQAFKATLEELGDADLLLHVVDVTNPNYTEQMDAVDTILNSLHLNEIPRMVVFNKADGLDEETHDILQKN
GALLVSAVTREGLSKLLDLIEYEIWKKKEQKLLEVTSS
>Mature_518_residues
MELARLVGEISVEMGRQVGLLIERTGYVTHLIVGNDHSIEIPHLDRYRVAHSRLRGLRLFHTHLKEQPLNQEDLMDLVLN
RFDSITAACVDKEGIPKFFFSAFINPDPDAKEPWILSPKQYPGQIKYGYSEQVDALESEFTKKTSNLKESQKENRAFLVG
VYDVRKMKRSPEHSMDELKELCRTAGIHVVDTYVQKRDPDPRTVVGKGKLQEIILTSVHKDIEHLIFDLELTPSQAKKIS
DASDLKIIDRTQLILDIFSKNAKSRDGKLQVELAQLKYLKNRLSELDDNMSRLTGGIGGRGPGETKLEIGNRRVEEKINR
LENELKDLKRRRELNRKSRSRNEIPIVGIVGYTNAGKSTLLNALTNSTVIAEDKLFATLDPTTRRIRFPEEREIIISDTV
GFIHDLPPDLSQAFKATLEELGDADLLLHVVDVTNPNYTEQMDAVDTILNSLHLNEIPRMVVFNKADGLDEETHDILQKN
GALLVSAVTREGLSKLLDLIEYEIWKKKEQKLLEVTSS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=242, Percent_Identity=34.297520661157, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310133116, Length=189, Percent_Identity=38.0952380952381, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310124269, Length=171, Percent_Identity=39.766081871345, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310124267, Length=171, Percent_Identity=39.766081871345, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310124171, Length=171, Percent_Identity=39.766081871345, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI310124169, Length=171, Percent_Identity=39.766081871345, Blast_Score=122, Evalue=1e-27,
Organism=Escherichia coli, GI1790615, Length=328, Percent_Identity=41.7682926829268, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17561038, Length=339, Percent_Identity=28.9085545722714, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24650079, Length=319, Percent_Identity=33.8557993730408, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 58897; Mature: 58897

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELARLVGEISVEMGRQVGLLIERTGYVTHLIVGNDHSIEIPHLDRYRVAHSRLRGLRLF
CCHHHHHHHHHHHHCCHHCEEEEECCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHH
HTHLKEQPLNQEDLMDLVLNRFDSITAACVDKEGIPKFFFSAFINPDPDAKEPWILSPKQ
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEECCCC
YPGQIKYGYSEQVDALESEFTKKTSNLKESQKENRAFLVGVYDVRKMKRSPEHSMDELKE
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHH
LCRTAGIHVVDTYVQKRDPDPRTVVGKGKLQEIILTSVHKDIEHLIFDLELTPSQAKKIS
HHHHCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHEEEEECHHHHHHCC
DASDLKIIDRTQLILDIFSKNAKSRDGKLQVELAQLKYLKNRLSELDDNMSRLTGGIGGR
CCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPGETKLEIGNRRVEEKINRLENELKDLKRRRELNRKSRSRNEIPIVGIVGYTNAGKSTL
CCCCCEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
LNALTNSTVIAEDKLFATLDPTTRRIRFPEEREIIISDTVGFIHDLPPDLSQAFKATLEE
HHHHHCCEEEECCCEEEEECCCHHCCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHH
LGDADLLLHVVDVTNPNYTEQMDAVDTILNSLHLNEIPRMVVFNKADGLDEETHDILQKN
HCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCC
GALLVSAVTREGLSKLLDLIEYEIWKKKEQKLLEVTSS
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELARLVGEISVEMGRQVGLLIERTGYVTHLIVGNDHSIEIPHLDRYRVAHSRLRGLRLF
CCHHHHHHHHHHHHCCHHCEEEEECCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHH
HTHLKEQPLNQEDLMDLVLNRFDSITAACVDKEGIPKFFFSAFINPDPDAKEPWILSPKQ
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEECCCC
YPGQIKYGYSEQVDALESEFTKKTSNLKESQKENRAFLVGVYDVRKMKRSPEHSMDELKE
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHH
LCRTAGIHVVDTYVQKRDPDPRTVVGKGKLQEIILTSVHKDIEHLIFDLELTPSQAKKIS
HHHHCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHEEEEECHHHHHHCC
DASDLKIIDRTQLILDIFSKNAKSRDGKLQVELAQLKYLKNRLSELDDNMSRLTGGIGGR
CCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPGETKLEIGNRRVEEKINRLENELKDLKRRRELNRKSRSRNEIPIVGIVGYTNAGKSTL
CCCCCEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
LNALTNSTVIAEDKLFATLDPTTRRIRFPEEREIIISDTVGFIHDLPPDLSQAFKATLEE
HHHHHCCEEEECCCEEEEECCCHHCCCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHH
LGDADLLLHVVDVTNPNYTEQMDAVDTILNSLHLNEIPRMVVFNKADGLDEETHDILQKN
HCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCC
GALLVSAVTREGLSKLLDLIEYEIWKKKEQKLLEVTSS
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]