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The map label for this gene is trpG2 [H]

Identifier: 183219485

GI number: 183219485

Start: 57274

End: 57843

Strand: Direct

Name: trpG2 [H]

Synonym: LEPBI_I0058

Alternate gene names: 183219485

Gene position: 57274-57843 (Clockwise)

Preceding gene: 183219484

Following gene: 183219486

Centisome position: 1.59

GC content: 38.25

Gene sequence:

>570_bases
ATGTTTTTACTCATCGATAACTACGATTCATTCACTTATATTTTATACCAATACCTGAACAAAATCGCACCTACAACTGT
AATGCGAAATGACGAAAACCTTCCATTGGATACCATTCAAAAATACCAAGCCGTTGTTTTATCACCAGGACCAGGATTAC
CCAAAACTTCAGGCAAACTCGTGTCACATTTTTTTGAACTATATCCAAAAATGCCTGTGTTAGGAATTTGTCTCGGCCAC
CAAACCATTGCAGAATCATTTGGTGCAAAACTAGAACAAACTGAAGACATTTATCATGGTAGACCTTCTCAAATCCAACA
TAATGGCGAAGGAATCTTTAAAAAGATTCCAAATCATTTTTTAGCCAATCGTTACCACTCCTGGGCCGTTTCAAAAGTGA
ATTTTCCGGATGAATTGGAAGTGACAGCAGAAACGAAAGATGGTGTGATCATGGGAATTCGTCACAGAAAATGGAAAAAG
GTTTTTGGGGTTCAGTTCCATCCCGAATCCATCCTCACTGAATATGGGGAAACCTTACTTCGTAACTTCTTTGAGGAAGT
TCATTCATGA

Upstream 100 bases:

>100_bases
AATTCCTCAACGACGGAGTTGGGATCGAAACTCCGAACGCTTAAAAGTTGGAATTGGGATCAGTGGATTTGAGATTCCAC
TCCACTGATCCTATCCGAAT

Downstream 100 bases:

>100_bases
AATATTTTTTAAGACTACTGAGTTATAGCGTTCATTATAGACAACGATTTGTTTTAGGACTGGTCTTTGCTCTATTAACA
GCTGTACTCAATGGTATCTC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MFLLIDNYDSFTYILYQYLNKIAPTTVMRNDENLPLDTIQKYQAVVLSPGPGLPKTSGKLVSHFFELYPKMPVLGICLGH
QTIAESFGAKLEQTEDIYHGRPSQIQHNGEGIFKKIPNHFLANRYHSWAVSKVNFPDELEVTAETKDGVIMGIRHRKWKK
VFGVQFHPESILTEYGETLLRNFFEEVHS

Sequences:

>Translated_189_residues
MFLLIDNYDSFTYILYQYLNKIAPTTVMRNDENLPLDTIQKYQAVVLSPGPGLPKTSGKLVSHFFELYPKMPVLGICLGH
QTIAESFGAKLEQTEDIYHGRPSQIQHNGEGIFKKIPNHFLANRYHSWAVSKVNFPDELEVTAETKDGVIMGIRHRKWKK
VFGVQFHPESILTEYGETLLRNFFEEVHS
>Mature_189_residues
MFLLIDNYDSFTYILYQYLNKIAPTTVMRNDENLPLDTIQKYQAVVLSPGPGLPKTSGKLVSHFFELYPKMPVLGICLGH
QTIAESFGAKLEQTEDIYHGRPSQIQHNGEGIFKKIPNHFLANRYHSWAVSKVNFPDELEVTAETKDGVIMGIRHRKWKK
VFGVQFHPESILTEYGETLLRNFFEEVHS

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=44.6236559139785, Blast_Score=168, Evalue=2e-43,
Organism=Escherichia coli, GI1787517, Length=186, Percent_Identity=40.3225806451613, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI193204318, Length=140, Percent_Identity=30.7142857142857, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=43.7837837837838, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=32.8571428571429, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21744; Mature: 21744

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLIDNYDSFTYILYQYLNKIAPTTVMRNDENLPLDTIQKYQAVVLSPGPGLPKTSGKL
CEEEEECCCHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHEEEECCCCCCCCCHHHH
VSHFFELYPKMPVLGICLGHQTIAESFGAKLEQTEDIYHGRPSQIQHNGEGIFKKIPNHF
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCHHH
LANRYHSWAVSKVNFPDELEVTAETKDGVIMGIRHRKWKKVFGVQFHPESILTEYGETLL
HHHHHHHHEEEECCCCCCEEEEEECCCCEEECCCHHHHHHHHCCEECHHHHHHHHHHHHH
RNFFEEVHS
HHHHHHHCC
>Mature Secondary Structure
MFLLIDNYDSFTYILYQYLNKIAPTTVMRNDENLPLDTIQKYQAVVLSPGPGLPKTSGKL
CEEEEECCCHHHHHHHHHHHHHCCHHEEECCCCCCHHHHHHHHEEEECCCCCCCCCHHHH
VSHFFELYPKMPVLGICLGHQTIAESFGAKLEQTEDIYHGRPSQIQHNGEGIFKKIPNHF
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCHHH
LANRYHSWAVSKVNFPDELEVTAETKDGVIMGIRHRKWKKVFGVQFHPESILTEYGETLL
HHHHHHHHEEEECCCCCCEEEEEECCCCEEECCCHHHHHHHHCCEECHHHHHHHHHHHHH
RNFFEEVHS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]