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The map label for this gene is ltrA [H]

Identifier: 182677572

GI number: 182677572

Start: 640923

End: 641837

Strand: Direct

Name: ltrA [H]

Synonym: Bind_0577

Alternate gene names: 182677572

Gene position: 640923-641837 (Clockwise)

Preceding gene: 182677570

Following gene: 182677573

Centisome position: 15.37

GC content: 56.5

Gene sequence:

>915_bases
ATGGACGATATAAGTCTTTCGCATATTTTTCTTGTCTGCGCGGATGAGGGGAGTTTCTCGGCGGCTGGCAGGAAACTGAA
CCTTTCTCGCTCGTCGGTCGGCAAAACTGTTGCACGATTGGAAGACATGCTGGGGGTGCGGCTTTTCCATCGCTCAACCC
GGCATCAGGCCCTCACTGAAGAGGGAAAAATCTATTACGAACATGCCCGGCGAGCACACAATGAGTTGGATAGGGCGCGC
CAAATATTCGCGTCCGGTCACCGTTCGCCGAGCGGAATCCTGCGCGTGACCGCTCCAATGAGTTTGGGGCGGTCTTGCAT
CGGCCCGCTCCTTCTTGATTTTACGTCGCGATTTTCCGACCTCAAGCTTGTACTCTCTTTGAATGATCGGCCGGTTGATC
TCATCGACGAGGGATTTGATCTCGCGATCCGCGTTGGAGCCACGATCAACACGACAGGGATAGCGGGGCGAAAGCTCAGT
ACCCAAGCCATGAGGCTTTACGCCTCGCCTTCCTACTTAGGGGCAAGGGGAACCCCTAAGAGCTGCGGGGAATTCGATCA
GCATCAAATCCTCGCCTATGGTCGAGGGCGGACTCTGCGCTGGCGCTTTGCCGGTGTGGGCGGACAAGCGCTCCAAGACG
TAGAGGGCATGAGTCAAGCGCAATTTGACGATCTGGATCTGCTGGCGAATGCGACGGCCCAGGGCTTCGGCATTGCCTCG
CTGCCGACATGGCTGGCGCACCCTCGTGCTTTGCGAGGAGAATTGGTGCCTTTAAAGGCGTTCAATCTGAAGCCGTATGA
TATCAGCGCCCTCTGGCCGCAAAGTCATTTCATGCCACCGAAGGTCCGATATGCGATCGACCATCTGGTTCAGGCCCTGC
CTGGCCTTCTGACAGACGACTTGAAAGGTCACTGA

Upstream 100 bases:

>100_bases
TCATCGCGTCATAAAGCGCTTCTTCCTTACCTGGGCCTGACAGATTGAACCAGTGCTCAGCCCGACAGGAGGGCGTTCCT
TAAAGGAAAGGCAGAGACAG

Downstream 100 bases:

>100_bases
AGCGAAGTCTTCTCTGAAAGATTGTCGCTCTCAACGCGACAGTCATCGGCTCAAACGGATCGAATTGCCCTTCCTGAAGC
ATGCTATTTGTGTATGCAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDDISLSHIFLVCADEGSFSAAGRKLNLSRSSVGKTVARLEDMLGVRLFHRSTRHQALTEEGKIYYEHARRAHNELDRAR
QIFASGHRSPSGILRVTAPMSLGRSCIGPLLLDFTSRFSDLKLVLSLNDRPVDLIDEGFDLAIRVGATINTTGIAGRKLS
TQAMRLYASPSYLGARGTPKSCGEFDQHQILAYGRGRTLRWRFAGVGGQALQDVEGMSQAQFDDLDLLANATAQGFGIAS
LPTWLAHPRALRGELVPLKAFNLKPYDISALWPQSHFMPPKVRYAIDHLVQALPGLLTDDLKGH

Sequences:

>Translated_304_residues
MDDISLSHIFLVCADEGSFSAAGRKLNLSRSSVGKTVARLEDMLGVRLFHRSTRHQALTEEGKIYYEHARRAHNELDRAR
QIFASGHRSPSGILRVTAPMSLGRSCIGPLLLDFTSRFSDLKLVLSLNDRPVDLIDEGFDLAIRVGATINTTGIAGRKLS
TQAMRLYASPSYLGARGTPKSCGEFDQHQILAYGRGRTLRWRFAGVGGQALQDVEGMSQAQFDDLDLLANATAQGFGIAS
LPTWLAHPRALRGELVPLKAFNLKPYDISALWPQSHFMPPKVRYAIDHLVQALPGLLTDDLKGH
>Mature_304_residues
MDDISLSHIFLVCADEGSFSAAGRKLNLSRSSVGKTVARLEDMLGVRLFHRSTRHQALTEEGKIYYEHARRAHNELDRAR
QIFASGHRSPSGILRVTAPMSLGRSCIGPLLLDFTSRFSDLKLVLSLNDRPVDLIDEGFDLAIRVGATINTTGIAGRKLS
TQAMRLYASPSYLGARGTPKSCGEFDQHQILAYGRGRTLRWRFAGVGGQALQDVEGMSQAQFDDLDLLANATAQGFGIAS
LPTWLAHPRALRGELVPLKAFNLKPYDISALWPQSHFMPPKVRYAIDHLVQALPGLLTDDLKGH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=30.3754266211604, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=29.6551724137931, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693193, Length=306, Percent_Identity=31.6993464052288, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787128, Length=239, Percent_Identity=29.7071129707113, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=29.0657439446367, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787589, Length=236, Percent_Identity=27.9661016949153, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789440, Length=282, Percent_Identity=26.241134751773, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788706, Length=140, Percent_Identity=34.2857142857143, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786448, Length=143, Percent_Identity=32.1678321678322, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=33.6206896551724, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33446; Mature: 33446

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDISLSHIFLVCADEGSFSAAGRKLNLSRSSVGKTVARLEDMLGVRLFHRSTRHQALTE
CCCCCEEEEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGKIYYEHARRAHNELDRARQIFASGHRSPSGILRVTAPMSLGRSCIGPLLLDFTSRFSD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCHHHHHHHHHHHHHCCCC
LKLVLSLNDRPVDLIDEGFDLAIRVGATINTTGIAGRKLSTQAMRLYASPSYLGARGTPK
EEEEEEECCCCHHHHCCCCEEEEEECCEEECCCCCCCCHHHHHHHEECCCCCCCCCCCCC
SCGEFDQHQILAYGRGRTLRWRFAGVGGQALQDVEGMSQAQFDDLDLLANATAQGFGIAS
CCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCC
LPTWLAHPRALRGELVPLKAFNLKPYDISALWPQSHFMPPKVRYAIDHLVQALPGLLTDD
CCHHHCCCHHHCCCEEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHC
LKGH
CCCC
>Mature Secondary Structure
MDDISLSHIFLVCADEGSFSAAGRKLNLSRSSVGKTVARLEDMLGVRLFHRSTRHQALTE
CCCCCEEEEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGKIYYEHARRAHNELDRARQIFASGHRSPSGILRVTAPMSLGRSCIGPLLLDFTSRFSD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCHHHHHHHHHHHHHCCCC
LKLVLSLNDRPVDLIDEGFDLAIRVGATINTTGIAGRKLSTQAMRLYASPSYLGARGTPK
EEEEEEECCCCHHHHCCCCEEEEEECCEEECCCCCCCCHHHHHHHEECCCCCCCCCCCCC
SCGEFDQHQILAYGRGRTLRWRFAGVGGQALQDVEGMSQAQFDDLDLLANATAQGFGIAS
CCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCC
LPTWLAHPRALRGELVPLKAFNLKPYDISALWPQSHFMPPKVRYAIDHLVQALPGLLTDD
CCHHHCCCHHHCCCEEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHC
LKGH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]