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The map label for this gene is yafC [H]

Identifier: 182677541

GI number: 182677541

Start: 603905

End: 604819

Strand: Direct

Name: yafC [H]

Synonym: Bind_0546

Alternate gene names: 182677541

Gene position: 603905-604819 (Clockwise)

Preceding gene: 182677539

Following gene: 182677551

Centisome position: 14.48

GC content: 59.89

Gene sequence:

>915_bases
ATGGATAATCGTGCGGGCGAGATGCTGGTTTTCGTGCGCGTGGTGGAGGCGGGAAGCTTTTCGGAAGCGGCTCGTCAGAT
GCTGATGACACCCTCCACGATCAGCAAACTGATCGCCCGGCTTGAGGAACGCCTGGGGCTGAGGTTGCTTGAGCGTTCGA
CGCGCCGGCTTTCGCTGACGGATGAAGGGAGGATCTATTACGAGCGTAGCGCGGCCTTGCTTGCCGAGCTTGACGATATC
GAAGGCGCGCTTGCAAAAGGGGCTCGAAATGCCGGAGGAATTGTCCGGGTCAACGCCTCCGTGGCTTTCGGTGTCTTGGG
AATCGAACCGCTTCTCCCTGCCTTCTGGGAGGCCTATCCGCACATTGTCGTTGATCTCTCCCTTTCTGATGAAATCGTCG
ATCTCTATCTCGACCGCACCGATATTGCCTTTCGGGTCGGCGCTCTGTCCGATTCAGGCCTGATCGCGGTGCGGATCGGC
GTCTGCCGGCGCCGGATCGTGGCCTCCCCGGAATATCTCGAGCGCCATGGTACGCCTCAGACGATGGAGGATCTCGAGGG
GCATAATTGCCTTGGATTCAATTTCCGAAGGGCGGCCCCTGTCTGGCCTTTCAGGGAAGGGGGCCGGATCGTCGATCGGA
TCCTCGCTGGCACGCTCTTGGCCAATAATGGGGAGACTGTCCATCGCATGGCTAAAGCGGGGGTCGGGCTTGCGCGGCTC
GCGGATTTTCATACGCGCGCCGACATCGCTTCCGGTTGCCTGGTCGAGGTTTTGGATGGCATCGGCTATGATGACGAGGA
GGAAATCCACGCGCTTTACCTTGGTGGCCAGCGCATGCCGCAGCGTATCCGCCTGTTCCTCGATTTCATGGTGCCCAGAC
TGCAGCAGTTTCTGCGCGGCGGGGTCAAAGAGTAA

Upstream 100 bases:

>100_bases
CCCAAGCCTCAGCCGGCCCGGAACGCGGCTCCTATGCCTCTTGGTCATTGCCTCTCTTCCCGCATCGTTTTAGACGGGAG
TTCATAGAGGAAAGGGCAAG

Downstream 100 bases:

>100_bases
TCAGCCCCTTATCATGTTGCCGCCGACGCTCCGTGCTATGCGATATTTCAAGGCTTCAACAATTCGAAGGACTGGTCGGA
GGCTCGCAGTGCGTTTGTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDNRAGEMLVFVRVVEAGSFSEAARQMLMTPSTISKLIARLEERLGLRLLERSTRRLSLTDEGRIYYERSAALLAELDDI
EGALAKGARNAGGIVRVNASVAFGVLGIEPLLPAFWEAYPHIVVDLSLSDEIVDLYLDRTDIAFRVGALSDSGLIAVRIG
VCRRRIVASPEYLERHGTPQTMEDLEGHNCLGFNFRRAAPVWPFREGGRIVDRILAGTLLANNGETVHRMAKAGVGLARL
ADFHTRADIASGCLVEVLDGIGYDDEEEIHALYLGGQRMPQRIRLFLDFMVPRLQQFLRGGVKE

Sequences:

>Translated_304_residues
MDNRAGEMLVFVRVVEAGSFSEAARQMLMTPSTISKLIARLEERLGLRLLERSTRRLSLTDEGRIYYERSAALLAELDDI
EGALAKGARNAGGIVRVNASVAFGVLGIEPLLPAFWEAYPHIVVDLSLSDEIVDLYLDRTDIAFRVGALSDSGLIAVRIG
VCRRRIVASPEYLERHGTPQTMEDLEGHNCLGFNFRRAAPVWPFREGGRIVDRILAGTLLANNGETVHRMAKAGVGLARL
ADFHTRADIASGCLVEVLDGIGYDDEEEIHALYLGGQRMPQRIRLFLDFMVPRLQQFLRGGVKE
>Mature_304_residues
MDNRAGEMLVFVRVVEAGSFSEAARQMLMTPSTISKLIARLEERLGLRLLERSTRRLSLTDEGRIYYERSAALLAELDDI
EGALAKGARNAGGIVRVNASVAFGVLGIEPLLPAFWEAYPHIVVDLSLSDEIVDLYLDRTDIAFRVGALSDSGLIAVRIG
VCRRRIVASPEYLERHGTPQTMEDLEGHNCLGFNFRRAAPVWPFREGGRIVDRILAGTLLANNGETVHRMAKAGVGLARL
ADFHTRADIASGCLVEVLDGIGYDDEEEIHALYLGGQRMPQRIRLFLDFMVPRLQQFLRGGVKE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=304, Percent_Identity=34.8684210526316, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=31.5789473684211, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI145693193, Length=308, Percent_Identity=30.1948051948052, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=29.1525423728814, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=30.7958477508651, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787589, Length=262, Percent_Identity=29.7709923664122, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=27.1777003484321, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788481, Length=265, Percent_Identity=26.7924528301887, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=28.6290322580645, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI157672245, Length=133, Percent_Identity=32.3308270676692, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786448, Length=186, Percent_Identity=28.494623655914, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33675; Mature: 33675

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRAGEMLVFVRVVEAGSFSEAARQMLMTPSTISKLIARLEERLGLRLLERSTRRLSLT
CCCCHHCEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
DEGRIYYERSAALLAELDDIEGALAKGARNAGGIVRVNASVAFGVLGIEPLLPAFWEAYP
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHEEEHHCHHHHHHHHHHCCC
HIVVDLSLSDEIVDLYLDRTDIAFRVGALSDSGLIAVRIGVCRRRIVASPEYLERHGTPQ
CEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCC
TMEDLEGHNCLGFNFRRAAPVWPFREGGRIVDRILAGTLLANNGETVHRMAKAGVGLARL
HHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
ADFHTRADIASGCLVEVLDGIGYDDEEEIHALYLGGQRMPQRIRLFLDFMVPRLQQFLRG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
GVKE
CCCC
>Mature Secondary Structure
MDNRAGEMLVFVRVVEAGSFSEAARQMLMTPSTISKLIARLEERLGLRLLERSTRRLSLT
CCCCHHCEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
DEGRIYYERSAALLAELDDIEGALAKGARNAGGIVRVNASVAFGVLGIEPLLPAFWEAYP
CCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHEEEHHCHHHHHHHHHHCCC
HIVVDLSLSDEIVDLYLDRTDIAFRVGALSDSGLIAVRIGVCRRRIVASPEYLERHGTPQ
CEEEEECCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHCCHHHHHHCCCCC
TMEDLEGHNCLGFNFRRAAPVWPFREGGRIVDRILAGTLLANNGETVHRMAKAGVGLARL
HHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
ADFHTRADIASGCLVEVLDGIGYDDEEEIHALYLGGQRMPQRIRLFLDFMVPRLQQFLRG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
GVKE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]