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The map label for this gene is nlpI [C]

Identifier: 182677316

GI number: 182677316

Start: 363146

End: 364051

Strand: Direct

Name: nlpI [C]

Synonym: Bind_0319

Alternate gene names: 182677316

Gene position: 363146-364051 (Clockwise)

Preceding gene: 182677315

Following gene: 182677317

Centisome position: 8.71

GC content: 60.26

Gene sequence:

>906_bases
ATGGAGAGGTTCCGCATCAGGAGCGACATGCGACAGAACCAGAAATGCCTTGCTGCGCGGGCTATCGCGCATGTTGGTCG
CGTCCGCTTCGGCCTTATCGCCTTGAGCGCTGGAGCGCTGGCCGGATGCGGTGCCAACGGCATTTCCGGCATGCATGGCA
CTGGTGTTGCCGAAGTCGCGAACCAGTCCCCGCAAGAGGCTTCCGCCAATCTCGCTTCGCTCAGCGATGTCGTTTCCCGC
AATCCGCGCAGTTCGGAAGCCTATGACACGCGTGGCGTGGCCTATGCCAAGCTTGGCAAATATTCCGAGGCGATCAGCGA
TTTCTCGCAGGCGATCAAGCTCGATCCGAATAATGCCCCAGCCTATACCAATCGCGCGCTCGCCTATCGGCAGAGCAACC
GTAACGATGCCGCGCTGGCTGACTTCAACCGCGCGATCGAGGTCAATCCCCGTCATGCGCCGGCCTATCTCGGCCGCGCC
AATCTGCTGCGCGTCCAGGGCAATCTAGACGAGGCGAAATCCGATCTCGATCAGGCGATCAAGCTCAATCCCGAAAACGC
CCAAGCTTTTCATGCGCGCGGCCTGATCTATCAGCGCGAAGGCAATCAGCCGCAAGCCATTACCGATTTCGACAATGCCA
TTGACCGCGATCCCTTTGCCGGCGCGCCCTATCTGGCGCGCGGCCAAAGCCTCATCGCGACCGGCAAATATGACAAGGCG
ATCGAGGATTTCAACGCGGCCTTGCATGTCGATAATAAGAATCCCGACGCTTGGGCCGGGCTTGGTCTGGCTTATGAAAA
ATCGGGTAATCGCACCAAGGCAGCGGAATCCTATCAAAGGGCGCTGACCTTCGACCCCAGCAACGGCCTCGCCAAGGAAG
GCTCGAGCCGCGTCGGGCGGGGGTGA

Upstream 100 bases:

>100_bases
ATCCCTTCCAGGGTGAGTTGGTGTGTTTTCAAATTGCTGACGTGACACCACTAACGCGACACAAGGGGCCGATGAGGCTA
GGCGCTGGAGAGTGACCCTC

Downstream 100 bases:

>100_bases
TCTGGATAGCCTGTCCAGGTGCCACAAAAGCTTGCAACTGATCGACTGAATGGCTGCTGCGGACCTTCAACGTCAATTGA
AGGTCCAGATCGGATGGGGA

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MERFRIRSDMRQNQKCLAARAIAHVGRVRFGLIALSAGALAGCGANGISGMHGTGVAEVANQSPQEASANLASLSDVVSR
NPRSSEAYDTRGVAYAKLGKYSEAISDFSQAIKLDPNNAPAYTNRALAYRQSNRNDAALADFNRAIEVNPRHAPAYLGRA
NLLRVQGNLDEAKSDLDQAIKLNPENAQAFHARGLIYQREGNQPQAITDFDNAIDRDPFAGAPYLARGQSLIATGKYDKA
IEDFNAALHVDNKNPDAWAGLGLAYEKSGNRTKAAESYQRALTFDPSNGLAKEGSSRVGRG

Sequences:

>Translated_301_residues
MERFRIRSDMRQNQKCLAARAIAHVGRVRFGLIALSAGALAGCGANGISGMHGTGVAEVANQSPQEASANLASLSDVVSR
NPRSSEAYDTRGVAYAKLGKYSEAISDFSQAIKLDPNNAPAYTNRALAYRQSNRNDAALADFNRAIEVNPRHAPAYLGRA
NLLRVQGNLDEAKSDLDQAIKLNPENAQAFHARGLIYQREGNQPQAITDFDNAIDRDPFAGAPYLARGQSLIATGKYDKA
IEDFNAALHVDNKNPDAWAGLGLAYEKSGNRTKAAESYQRALTFDPSNGLAKEGSSRVGRG
>Mature_301_residues
MERFRIRSDMRQNQKCLAARAIAHVGRVRFGLIALSAGALAGCGANGISGMHGTGVAEVANQSPQEASANLASLSDVVSR
NPRSSEAYDTRGVAYAKLGKYSEAISDFSQAIKLDPNNAPAYTNRALAYRQSNRNDAALADFNRAIEVNPRHAPAYLGRA
NLLRVQGNLDEAKSDLDQAIKLNPENAQAFHARGLIYQREGNQPQAITDFDNAIDRDPFAGAPYLARGQSLIATGKYDKA
IEDFNAALHVDNKNPDAWAGLGLAYEKSGNRTKAAESYQRALTFDPSNGLAKEGSSRVGRG

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI310123097, Length=171, Percent_Identity=35.0877192982456, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI310131789, Length=171, Percent_Identity=35.0877192982456, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI310110582, Length=171, Percent_Identity=35.0877192982456, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI170784867, Length=200, Percent_Identity=31, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI32307148, Length=237, Percent_Identity=27.4261603375527, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI32307150, Length=237, Percent_Identity=27.4261603375527, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI167466177, Length=217, Percent_Identity=27.6497695852535, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI167466175, Length=217, Percent_Identity=27.6497695852535, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI5453980, Length=202, Percent_Identity=28.2178217821782, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI54607135, Length=204, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI301336134, Length=260, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI83415184, Length=260, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224809432, Length=236, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI225735593, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI225735591, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=227, Percent_Identity=26.431718061674, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115532690, Length=227, Percent_Identity=26.431718061674, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17563052, Length=236, Percent_Identity=24.1525423728814, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319387, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17647755, Length=221, Percent_Identity=27.1493212669683, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24585827, Length=221, Percent_Identity=27.1493212669683, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24585829, Length=221, Percent_Identity=27.1493212669683, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583797, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583795, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583793, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076610, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920486, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 32366; Mature: 32366

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFRIRSDMRQNQKCLAARAIAHVGRVRFGLIALSAGALAGCGANGISGMHGTGVAEVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHH
NQSPQEASANLASLSDVVSRNPRSSEAYDTRGVAYAKLGKYSEAISDFSQAIKLDPNNAP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
AYTNRALAYRQSNRNDAALADFNRAIEVNPRHAPAYLGRANLLRVQGNLDEAKSDLDQAI
CCCCHHHEEECCCCCCCHHHHCCCEEEECCCCCCHHHCCCEEEEEECCHHHHHHHHHHHH
KLNPENAQAFHARGLIYQREGNQPQAITDFDNAIDRDPFAGAPYLARGQSLIATGKYDKA
CCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHCCCEEEEECCHHHH
IEDFNAALHVDNKNPDAWAGLGLAYEKSGNRTKAAESYQRALTFDPSNGLAKEGSSRVGR
HHHCCCEEEECCCCCCHHHCCCEEEECCCCCHHHHHHHHHHEEECCCCCCHHCCCCCCCC
G
C
>Mature Secondary Structure
MERFRIRSDMRQNQKCLAARAIAHVGRVRFGLIALSAGALAGCGANGISGMHGTGVAEVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHH
NQSPQEASANLASLSDVVSRNPRSSEAYDTRGVAYAKLGKYSEAISDFSQAIKLDPNNAP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCC
AYTNRALAYRQSNRNDAALADFNRAIEVNPRHAPAYLGRANLLRVQGNLDEAKSDLDQAI
CCCCHHHEEECCCCCCCHHHHCCCEEEECCCCCCHHHCCCEEEEEECCHHHHHHHHHHHH
KLNPENAQAFHARGLIYQREGNQPQAITDFDNAIDRDPFAGAPYLARGQSLIATGKYDKA
CCCCCCCHHHHHCCEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHCCCEEEEECCHHHH
IEDFNAALHVDNKNPDAWAGLGLAYEKSGNRTKAAESYQRALTFDPSNGLAKEGSSRVGR
HHHCCCEEEECCCCCCHHHCCCEEEECCCCCHHHHHHHHHHEEECCCCCCHHCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]