Click here to switch to the map view.

The map label for this gene is queC [H]

Identifier: 182677257

GI number: 182677257

Start: 296560

End: 297285

Strand: Direct

Name: queC [H]

Synonym: Bind_0258

Alternate gene names: 182677257

Gene position: 296560-297285 (Clockwise)

Preceding gene: 182677256

Following gene: 182677258

Centisome position: 7.11

GC content: 60.19

Gene sequence:

>726_bases
ATGCCGGAACACAGTTCAGACACGGGCAACAACAAGGCCCTGGTCCTGTTTTCCGGCGGCCAGGATTCCACGACCTGCCT
CGCATGGGCGCTCGATCGATTCGCCTTTGTCGAGACGATTGGTTTTTCCTACGGACAGCGCCATGTGATCGAACTCACGC
AGCGCCAAGTGGTGCGCGCTTCGATCGCGCGGCAATTCCCGGCCTGGGCTGAGAGGCTTGGGGACGATCATCTCGTCACC
ATCGAGGCCCTAGCGGAGATTTCGCAAACCGCGCTTACGCGGGATATGGCCATTGAAATGGATGCGCAGGGCCTGCCCAA
TACATTTGTGCCGGGGCGTAATCTGCTCTTTTTGACTTTCGCCGGCGCGCTCGGCTATCGGCGCGGCCTCAAACATATCG
TCGGCGGCATGTGCGAGACGGATTTTTCCGGTTACCCCGATTGCCGTGACGACACGGTGAAGGCCATGCAAGTCGCGCTC
AATCTCGGCATGGATCGCCGCTTTGTTTTAGAAACGCCCTTGATGTGGCTCGATAAGGCGGAGACTTGGCGGCTCGCCGA
AGCGCTCGGCGGCCAAGCCCTCGTCGATCTCATTATCGAGGAGACCCATACCTGTTATCTCGGCGAACGCGGTGCGCTTC
ACGCCTGGGGACATGGCTGTGGTCAATGTCCGGCCTGCGTCCTGCGGGCCAAAGGCTATGCGGCTTATCGCGACGGCGTG
GCTTAA

Upstream 100 bases:

>100_bases
TGCTCCTGCGCCGCTGGGCTTCCGAGAGTTTAACCTTTTGACTTTGGCGCCGCCCTGTTGAACATGCCCGGATTTCACGA
AAGCGACGGGATAGACAGCC

Downstream 100 bases:

>100_bases
GCCGGAAACGATGGAAAGAAAATTTTCGCGCGGGCCTTTGTAATAGTTTCGGCCGGCCGAACGAAAGATCTCATGTGGCC
AAGTTGAAGCCATATCCGCT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MPEHSSDTGNNKALVLFSGGQDSTTCLAWALDRFAFVETIGFSYGQRHVIELTQRQVVRASIARQFPAWAERLGDDHLVT
IEALAEISQTALTRDMAIEMDAQGLPNTFVPGRNLLFLTFAGALGYRRGLKHIVGGMCETDFSGYPDCRDDTVKAMQVAL
NLGMDRRFVLETPLMWLDKAETWRLAEALGGQALVDLIIEETHTCYLGERGALHAWGHGCGQCPACVLRAKGYAAYRDGV
A

Sequences:

>Translated_241_residues
MPEHSSDTGNNKALVLFSGGQDSTTCLAWALDRFAFVETIGFSYGQRHVIELTQRQVVRASIARQFPAWAERLGDDHLVT
IEALAEISQTALTRDMAIEMDAQGLPNTFVPGRNLLFLTFAGALGYRRGLKHIVGGMCETDFSGYPDCRDDTVKAMQVAL
NLGMDRRFVLETPLMWLDKAETWRLAEALGGQALVDLIIEETHTCYLGERGALHAWGHGCGQCPACVLRAKGYAAYRDGV
A
>Mature_240_residues
PEHSSDTGNNKALVLFSGGQDSTTCLAWALDRFAFVETIGFSYGQRHVIELTQRQVVRASIARQFPAWAERLGDDHLVTI
EALAEISQTALTRDMAIEMDAQGLPNTFVPGRNLLFLTFAGALGYRRGLKHIVGGMCETDFSGYPDCRDDTVKAMQVALN
LGMDRRFVLETPLMWLDKAETWRLAEALGGQALVDLIIEETHTCYLGERGALHAWGHGCGQCPACVLRAKGYAAYRDGVA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=230, Percent_Identity=46.9565217391304, Blast_Score=196, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 26498; Mature: 26366

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEHSSDTGNNKALVLFSGGQDSTTCLAWALDRFAFVETIGFSYGQRHVIELTQRQVVRA
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SIARQFPAWAERLGDDHLVTIEALAEISQTALTRDMAIEMDAQGLPNTFVPGRNLLFLTF
HHHHHCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEEE
AGALGYRRGLKHIVGGMCETDFSGYPDCRDDTVKAMQVALNLGMDRRFVLETPLMWLDKA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCC
ETWRLAEALGGQALVDLIIEETHTCYLGERGALHAWGHGCGQCPACVLRAKGYAAYRDGV
HHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCEECCCCCCCCHHHHHHHHCCCHHHCCCC
A
C
>Mature Secondary Structure 
PEHSSDTGNNKALVLFSGGQDSTTCLAWALDRFAFVETIGFSYGQRHVIELTQRQVVRA
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SIARQFPAWAERLGDDHLVTIEALAEISQTALTRDMAIEMDAQGLPNTFVPGRNLLFLTF
HHHHHCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEEE
AGALGYRRGLKHIVGGMCETDFSGYPDCRDDTVKAMQVALNLGMDRRFVLETPLMWLDKA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCC
ETWRLAEALGGQALVDLIIEETHTCYLGERGALHAWGHGCGQCPACVLRAKGYAAYRDGV
HHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCEECCCCCCCCHHHHHHHHCCCHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA