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The map label for this gene is aroE [H]

Identifier: 182677106

GI number: 182677106

Start: 117724

End: 118578

Strand: Direct

Name: aroE [H]

Synonym: Bind_0104

Alternate gene names: 182677106

Gene position: 117724-118578 (Clockwise)

Preceding gene: 182677105

Following gene: 182677110

Centisome position: 2.82

GC content: 57.43

Gene sequence:

>855_bases
ATGTCCGAACATCATTTCCTGAGCCTTTTGACCGGCTCTTTTTCAACGCCTTCGGATGATAATCCGACCGTGGCTATGGT
CGAGGCGGCTTATCGTCATCATGGCATCAATGCCCGTTACATCAATTGCGATGTCAAGAAAGACAATCTTGCCGATGCCA
TTCGCGGCGCCAAGGCGATGGAATGGATCGGCTTCAATTGCTCCATGCCGCATAAGGTGGCGGTCATCGATCATTTGGAC
GGGCTCGCCGAATCCGCTGCCATCATCGGTGCTGTCAATTGCGTGGTCATCGCCGACGGCAAGCTGACGGGTCATAATAC
TGATGGCCAGGGCTTTCTGACCTCCCTGCAAAGCGTGACCGATCCCAAGGATAAACGCATTACCTTGCTCGGCGCTGGTG
GCGCGGCGCGGGCCATTGCCGTGGAATTGGCGCTCGCCGGTGCCACGCATATTGGCATTGTCAATCGTGATCAGAGCCGT
GGCGAATCACTTGCCAAATTGATCAGCGAGAAGACCAAGGCCAAGGCGGATTTCATTCCCTGGACCAGCGGCTATCGCGT
TCCTGAAACAACCGATGTGCTGGTCAATGCGACGTCCATCGGGCTTGGCGACGCCGAGGCACTGCCTGACATTGACACGG
GCTCCTTGCGCAAGGGAATGATCGTCGCCGATGTCATTTTCAATCCGCCGCGCACACATCTTCTGCGCAAGGCGGAGGAA
CAAGGTGCCGTCACGCTCGACGGGCTCGGAATGCTGGTTAATCAAGGCCGTGTCGGCATCAAGCTCTGGACCGGCAAGGA
TGTCGAAGCCTCTGTCATGCACGCGACGCTGGCGACCCTGTTCGGCGTCGCCTGA

Upstream 100 bases:

>100_bases
CTGAGATCGTCCGTCACCAAATCACGTCCAGATTTTTGAAAATGCATCAAATTGAGTCCAAAAGCGTTCTTCGCTTGGGG
TTTGATGCGGGGGGAAGCAT

Downstream 100 bases:

>100_bases
CACACGATCCTATTCATAAAAAATCGGCCCCGCAGCGATGTGCTGACGGGGCCGATTTTGCGTTTCGTTTGCATCATCCA
TCGACTTCACGAATGCGGCT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSEHHFLSLLTGSFSTPSDDNPTVAMVEAAYRHHGINARYINCDVKKDNLADAIRGAKAMEWIGFNCSMPHKVAVIDHLD
GLAESAAIIGAVNCVVIADGKLTGHNTDGQGFLTSLQSVTDPKDKRITLLGAGGAARAIAVELALAGATHIGIVNRDQSR
GESLAKLISEKTKAKADFIPWTSGYRVPETTDVLVNATSIGLGDAEALPDIDTGSLRKGMIVADVIFNPPRTHLLRKAEE
QGAVTLDGLGMLVNQGRVGIKLWTGKDVEASVMHATLATLFGVA

Sequences:

>Translated_284_residues
MSEHHFLSLLTGSFSTPSDDNPTVAMVEAAYRHHGINARYINCDVKKDNLADAIRGAKAMEWIGFNCSMPHKVAVIDHLD
GLAESAAIIGAVNCVVIADGKLTGHNTDGQGFLTSLQSVTDPKDKRITLLGAGGAARAIAVELALAGATHIGIVNRDQSR
GESLAKLISEKTKAKADFIPWTSGYRVPETTDVLVNATSIGLGDAEALPDIDTGSLRKGMIVADVIFNPPRTHLLRKAEE
QGAVTLDGLGMLVNQGRVGIKLWTGKDVEASVMHATLATLFGVA
>Mature_283_residues
SEHHFLSLLTGSFSTPSDDNPTVAMVEAAYRHHGINARYINCDVKKDNLADAIRGAKAMEWIGFNCSMPHKVAVIDHLDG
LAESAAIIGAVNCVVIADGKLTGHNTDGQGFLTSLQSVTDPKDKRITLLGAGGAARAIAVELALAGATHIGIVNRDQSRG
ESLAKLISEKTKAKADFIPWTSGYRVPETTDVLVNATSIGLGDAEALPDIDTGSLRKGMIVADVIFNPPRTHLLRKAEEQ
GAVTLDGLGMLVNQGRVGIKLWTGKDVEASVMHATLATLFGVA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=268, Percent_Identity=33.2089552238806, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789675, Length=215, Percent_Identity=35.8139534883721, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30001; Mature: 29869

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHHFLSLLTGSFSTPSDDNPTVAMVEAAYRHHGINARYINCDVKKDNLADAIRGAKAM
CCCCEEEEEEECCCCCCCCCCCCEEEEEHHHHHCCCCEEEEEEECCCCHHHHHHHCCHHH
EWIGFNCSMPHKVAVIDHLDGLAESAAIIGAVNCVVIADGKLTGHNTDGQGFLTSLQSVT
EEECCCCCCCCEEEEEHHHHHHHHHHHHEEEEEEEEEECCEEECCCCCCCHHHHHHHHHC
DPKDKRITLLGAGGAARAIAVELALAGATHIGIVNRDQSRGESLAKLISEKTKAKADFIP
CCCCCEEEEEECCCCHHHEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
WTSGYRVPETTDVLVNATSIGLGDAEALPDIDTGSLRKGMIVADVIFNPPRTHLLRKAEE
CCCCCCCCCCCEEEEEEEECCCCCHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
QGAVTLDGLGMLVNQGRVGIKLWTGKDVEASVMHATLATLFGVA
CCCEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEHHFLSLLTGSFSTPSDDNPTVAMVEAAYRHHGINARYINCDVKKDNLADAIRGAKAM
CCCEEEEEEECCCCCCCCCCCCEEEEEHHHHHCCCCEEEEEEECCCCHHHHHHHCCHHH
EWIGFNCSMPHKVAVIDHLDGLAESAAIIGAVNCVVIADGKLTGHNTDGQGFLTSLQSVT
EEECCCCCCCCEEEEEHHHHHHHHHHHHEEEEEEEEEECCEEECCCCCCCHHHHHHHHHC
DPKDKRITLLGAGGAARAIAVELALAGATHIGIVNRDQSRGESLAKLISEKTKAKADFIP
CCCCCEEEEEECCCCHHHEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCC
WTSGYRVPETTDVLVNATSIGLGDAEALPDIDTGSLRKGMIVADVIFNPPRTHLLRKAEE
CCCCCCCCCCCEEEEEEEECCCCCHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
QGAVTLDGLGMLVNQGRVGIKLWTGKDVEASVMHATLATLFGVA
CCCEEEECCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]